Research Topics
| Marcela FerresSummaryCountry: Chile Publications
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Detail Information
Publications
Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeabilityDelphine Marsac
UMR MD3 University Montpellier 1, Comparative Molecular Immuno Physiopathology Lab, Faculte de Pharmacie, 34093 Montpellier, France
Virol J 8:223. 2011..Activated immune cells, including DC, secrete gelatinolytic matrix metalloproteases (gMMP-2 and -9) that modulate the vascular permeability for their trafficking...
Hantavirus infection in childrenMarcela Ferres
Department of Pediatrics, Pontificia Universidad Catolica de Chile, Santiago, Chile
Curr Opin Pediatr 16:70-5. 2004..We highlight clinical characterization, epidemiology, pathogenesis, diagnostic techniques, and current alternatives for treatment and prevention...
[Hantavirosis: clinical and epidemiological characteristics of pediatric patients in Chile]Marcela Ferres G
Departamento de Pediatría y Laboratorio de Infectología y Virología Molecular, Pontificia Universidad Catolica de Chile, Santiago, Chile
Rev Chilena Infectol 27:52-9. 2010..The first cases of Hantavirus cardiopulmonary syndrome in children were described in the United States and represented 8% of the total reported cases; in Chile, the proportion of pediatric cases represents 15% of all national cases...
[Presence of Bartonella henselae in cats: natural reservoir quantification and human exposition risk of this zoonoses in Chile]Marcela Ferres
Departamento de Pediatria, Facultad de Medicina, Pontificia Universidad Catolica de Chile
Rev Med Chil 133:1465-71. 2005..The availability of a serologic test for cat scratch disease in humans has allowed the diagnosis of an increasing number of cases of this disease in Chile...
[Importance of images and etiological diagnosis of central nervous system involvement in immunocompromised patient]Marcela Ferres G
Hospital Clinico, Pontificia Universidad Católica de ChileSantiago, Chile
Rev Chilena Infectol 27:541-3. 2010..The invasive fungal CNS compromise has medical treatment and the surgical drainage has to be considered for lesions greater than 2 cm or for those making a mass effect or have failed with medical treatment...
[Prevalence of Bartonella henselae antibodies in Chilean children, adolescents and veterinary workers]Marcela Ferres G
Laboratorio de Infectología y Virología Molecular, Pontificia Universidad Catolica de Chile, Santiago, Chile
Rev Med Chil 134:863-7. 2006..Bartonella henselae is the causative agent of cat-scratch disease...
[Importance of images and etiological diagnosis in the immunocompromised patient with central nervous system envolvement. Part II]Marcela Zubieta
Hospital Exequiel Gonzalez Cortes, Santiago, Chile
Rev Chilena Infectol 28:359-62. 2011....
Highly differentiated, resting gn-specific memory CD8+ T cells persist years after infection by andes hantavirusTobias Manigold
Institute of Science, Medical School, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile
PLoS Pathog 6:e1000779. 2010..Furthermore, it remains to be seen whether Gn-specific T cells are critical for viral control and protective immunity. If so, Gn-derived immunodominant epitopes could be of high value for future ANDV vaccines...
Andes virus antigens are shed in urine of patients with acute hantavirus cardiopulmonary syndromePaula Godoy
Laboratorio de Infectología y Virología Molecular, Centro de Investigaciones Médicas y Departamento de Pediatría, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Marcoleta 391, Santiago, Chile
J Virol 83:5046-55. 2009..In addition, we report that ANDV-antigens and infectious virus are shed in urine of HCPS patients...
Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in chileMarcela Ferres
Department of Pediatrics and Virology Laboratory, Pontificia Universidad Catolica, Santiago, Chile
J Infect Dis 195:1563-71. 2007..Andes virus (ANDV) infection, which has a case fatality rate of 37% in Chile, often occurs in household clusters and may be transmitted from person to person...
Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infectionFrancisca Valdivieso
Universidad del Desarrollo, Santiago, Chile
Emerg Infect Dis 12:166-8. 2006..All but 1 patient had high titers of NAb. None of the plasma samples showed high titers against the heterologous virus...
[Human metapneumovirus as hospitalization cause in children under 3 years old with acute respiratory infections during 2004]M Alejandra Prado S
Pontificia Universidad Católica de Chile y Hospital Clínico Pontificia Universidad Católica de Chile
Rev Chilena Infectol 24:19-26. 2007..A rapid and sensitive diagnostic method is required to improve diagnosis and treatment of these patients...
[Clinical and epidemiological characteristics of respiratory virus infections among adults hospitalized during 2004 influenza season]Ricardo Rabagliati B
Departamento de Medicina Interna, Pontificia Universidad Catolica de Chile, Santiago, Chile
Rev Chilena Infectol 23:111-7. 2006....
[Influenza-A as etiology of fever and respiratory insufficiency in adults hospitalized during an outbreak in Chile]Ricardo Rabagliati
Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Santiago, Chile
Rev Med Chil 132:317-24. 2004..Influenza-A (IA) occurs every winter, is mostly observed among outpatients...
[Source of infection in young infants hospitalized with Bordetella pertussis]Cecilia Perret
División de Pediatría, Facultad de Medicina, Pontificia Universidad Católica de ChileTemuco, Chile
Rev Med Chil 139:448-54. 2011..Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile...
Dengue-1 virus isolation during first dengue fever outbreak on Easter Island, ChileCecilia Perret
Pontificia Universidad Catolica de Chile School of Medicine, Virology Laboratory, Santiago, Chile
Emerg Infect Dis 9:1465-7. 2003..Dengue virus was detected for the first time in Chile, in an outbreak of dengue fever on Easter Island. The virus was isolated in tissue culture and characterized by reverse transcription-polymerase chain reaction as being dengue type 1...
[Utility of real time polymerase chain reaction in the diagnosis of respiratory syncytial virus infection among adult patients]Ricardo Rabagliati
Programa de Enfermedades Infecciosas del adulto, Departamento de Medicina Interna, Pontificia Universidad Catolica de Chile, Santiago, Chile
Rev Chilena Infectol 24:441-5. 2007..Aim: To assess the impact of real time reverse transcriptase-polymerase chain reaction (real time RT-PCR) technique in RSV diagnosis in adult hospitalized patients; to characterize RSV infection among these patients...
[Clinical characteristics of respiratory infection due to Mycoplasma pneumoniae in hospitalized children]M de Los Angeles Paul D
Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago
Rev Chilena Infectol 26:343-9. 2009..Studies on Mycoplasma pneumoniae infection are scarce in Chile...
[Clinical and epidemiological manifestations of parainfluenza infection in hospitalized children]Luis E Vega-Briceño
Departamento de Pediatria, Pontificia Universidad Católica de ChileSantiago, Chile
Rev Chilena Infectol 24:377-83. 2007..Human parainfluenza viruses (hPIV) are a common cause of respiratory illness of children but published data on clinical characteristics of hPIV infection in South America is scarce...
[Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alíeles in Chilean patients]Pablo Ferrer C
Programa de Genética Humana, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
Rev Chilena Infectol 24:351-9. 2007..Although the association was marginally significant, alíele HLA-B*08 may be linked to an increased susceptibility to the severe clinical course of HCPS by ANDV...
Functional and Structural Analysis of the Internal Ribosome Entry Site Present in the mRNA of Natural Variants of the HIV-1Maricarmen Vallejos
Laboratorio de Virologia Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Medicas, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
PLoS ONE 7:e35031. 2012..3-5'UTR. Thus, the increased IRES-activity observed for some of the HIV-1 variants cannot be ascribed to a specific structural modification. A model to explain these findings is proposed...
[Presence of mutations associated with ganciclovir resistance in cytomegalovirus UL97 gene]María Angélica Oyarzún
Departamento de Pediatria, Centro de Investigaciones Medicas, Pontificia Universidad Catolica de Chile, Chile
Rev Med Chil 138:421-7. 2010..Long term use of ganciclovir (GCV) is associated with acquired resistance to it. Ninety percent of the responsible mutations occur in cytomegalovirus (CMV) UL 97 gene...
