Unique insertional translocation in a childhood Wilms' tumor survivor detected when his daughter developed bilateral retinoblastomaAngela Punnett
Division of Hematology/Oncology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada
Am J Med Genet A 120:105-9. 2003
..The estimated risk for an offspring of this father to develop Wilms' tumor is up to 50%, to develop retinoblastoma up to 25%, to have neither tumor 25%, and to have both tumors 0%...
- Chemotherapy for retinoblastoma
Helen S L Chan
Division of Hematology Oncology, Department of Pediatrics, Institute of Medical Science, University of Toronto, Ontario, Canada
Ophthalmol Clin North Am 18:55-63, viii. 2005
..Chemotherapy alone reduces tumor size but does not cure retinoblastoma. Focal therapy, consisting of photocoagulation, thermotherapy, cryotherapy, or brachytherapy, is necessary to consolidate chemotherapy response...
- Retinoblastoma CSF metastasis cured by multimodality chemotherapy without radiation
Helen Dimaras
Division of Hematology Oncology, The Hospital for Sick Children, and the University of Toronto, Toronto, Ontario, Canada
Ophthalmic Genet 30:121-6. 2009
..High-dose craniospinal radiation is too morbid for treatment of young children. To cure CSF metastasis without radiation, we designed an intensive multimodality chemotherapy regimen...
- Using RB1 mutations to assess minimal residual disease in metastatic retinoblastoma
Helen Dimaras
Divisions of Hematology Oncology, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
Transl Res 156:91-7. 2010
..A prospective international multicenter trial of the rare patients with metastatic retinoblastoma would assess the role of molecular monitoring in surveillance for minimal residual disease and recurrence...
- Trilateral retinoblastoma with pituitary-hypothalamic dysfunction
Shuan Dai
Department of Ophthalmology Visual Science, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Ophthalmic Genet 29:120-5. 2008
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- Periocular topotecan for intraocular retinoblastoma
Ashwin C Mallipatna
Departments of Ophthalmology and Visual Sciences, The Hospital for Sick Children, Ontario, Canada
Arch Ophthalmol 129:738-45. 2011
..To review the effectiveness and toxicity of periocular topotecan hydrochloride in fibrin sealant (Tisseel) for the control of intraocular retinoblastoma...
- Toxocariasis mimicking liver, lung, and spinal cord metastases from retinoblastoma
Kaede V Ota
Division of Infectious Diseases, University of Toronto, Toronto, Ontario, Canada
Pediatr Infect Dis J 28:252-4. 2009
..This is the first report of early, asymptomatic spinal cord toxocariasis diagnosed incidentally through metastatic surveillance...
- Retinoblastoma with central retinal artery thrombosis that mimics extraocular disease
Kathia Valverde
Division of Hematology and Oncology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
Med Pediatr Oncol 38:277-9. 2002
- Ocular motility changes after subtenon carboplatin chemotherapy for retinoblastoma
Alan Mulvihill
Department of Ophthalmology and Division of Hematology-Oncology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario
Arch Ophthalmol 121:1120-4. 2003
..Subtenon carboplatin is not free of toxicity, and its use is best restricted to specific indications...
- Global issues and opportunities for optimized retinoblastoma care
Brenda L Gallie
Retinoblastoma Program, Hospital for Sick Children and Applied Molecular Oncology, Ontario Cancer Institute Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Pediatr Blood Cancer 49:1083-90. 2007
..Global collaboration is building for the dramatic change in mortality that awareness, simple expertise and therapies could achieve in less developed countries...
- A visual approach to providing prognostic information to parents of children with retinoblastoma
Rachel L Panton
Department of Ophthalmology, Hospital for Sick Children, University of Toronto, Toronto, Ont, Canada
Psychooncology 18:300-4. 2009
..Education correlates with the ability to process and use medical information. Graphic tools aid reasoning and communicate complex ideas with precision and efficiency...
- Predilection of retinoblastoma metastases for the mandible
Jayshree Pandya
Division of Hematology and Oncology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
Med Pediatr Oncol 38:271-3. 2002
- Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation
Steven Gallinger
Familial Gastrointestinal Cancer Registry and Centre for Cancer Genetics and Department of Surgery, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, ON, Canada
Gastroenterology 126:576-85. 2004
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