Eric C Y Chan

Summary

Publications

  1. ncbi An automated LC method for the small-scale purification of organic molecules derived from combinatorial libraries
    Eric C Y Chan
    Analytical Chemistry, Chemistry Discovery, S B10 Pte Ltd, 1 Science Park Road, 05 09, The Capricon, Singapore Science Park II, Singapore 117528, Singapore
    J Pharm Biomed Anal 29:139-46. 2002
  2. ncbi Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng
    Eric C Y Chan
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore
    Rapid Commun Mass Spectrom 21:519-28. 2007
  3. ncbi Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry
    Lee Sun New
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543
    Rapid Commun Mass Spectrom 21:982-8. 2007
  4. ncbi Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine
    Su Ching Tan
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Toxicol Lett 180:174-81. 2008
  5. ncbi Development and validation of a gas chromatography/mass spectrometry metabonomic platform for the global profiling of urinary metabolites
    Kishore K Pasikanti
    Department of Pharmacy, National University of Singapore, Singapore 117543
    Rapid Commun Mass Spectrom 22:2984-92. 2008

Collaborators

  • Lee Sun New
  • Kishore K Pasikanti
  • Su Ching Tan
  • Paul C Ho
  • Sudipta Saha
  • Michie M K Ong
  • Lee-Sun New
  • Urs Alex Boelsterli

Detail Information

Publications5

  1. ncbi An automated LC method for the small-scale purification of organic molecules derived from combinatorial libraries
    Eric C Y Chan
    Analytical Chemistry, Chemistry Discovery, S B10 Pte Ltd, 1 Science Park Road, 05 09, The Capricon, Singapore Science Park II, Singapore 117528, Singapore
    J Pharm Biomed Anal 29:139-46. 2002
    ..It was also found that the C.V.% of recovery were less than 15% at both concentration levels. The development of this automated method was found to be straightforward. The importance and implications of this study were discussed...
  2. ncbi Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng
    Eric C Y Chan
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore
    Rapid Commun Mass Spectrom 21:519-28. 2007
    ..The application of this approach in herbal extract discrimination and ginsenoside biomarker discovery of raw and steamed Panax notoginseng (Burk.) F.H. Chen is demonstrated and discussed...
  3. ncbi Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry
    Lee Sun New
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543
    Rapid Commun Mass Spectrom 21:982-8. 2007
    ..1%; the overall accuracy ranged from 86.4-110.2% and recovery from spiked plasma was more than 60%. The developed method was successfully applied to determine troglitazone in mouse plasma after intraperitoneal administration...
  4. ncbi Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine
    Su Ching Tan
    Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Toxicol Lett 180:174-81. 2008
    ..We concluded that inhibition of NAPQI formation is not a probable pathway that LEF protects APAP-induced hepatotoxicity in human...
  5. ncbi Development and validation of a gas chromatography/mass spectrometry metabonomic platform for the global profiling of urinary metabolites
    Kishore K Pasikanti
    Department of Pharmacy, National University of Singapore, Singapore 117543
    Rapid Commun Mass Spectrom 22:2984-92. 2008
    ..This validated GC/MS metabolic profiling method may be further applied to the metabonomic screening of urinary biomarkers in clinical studies...