Marc Tini

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription
    Marc Tini
    Gene Expression Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Mol Cell 9:265-77. 2002
  2. ncbi The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation
    Hina Naeem
    Cancer Research Laboratories, London Regional Cancer Program, London, Ontario, Canada N6A 4L6
    Mol Cell Biol 27:120-34. 2007
  3. ncbi SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment
    Ryan D Mohan
    Department of Physiology and Pharmacology, Siebens Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6G 2V4
    Mol Cell Biol 27:229-43. 2007
  4. ncbi Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex
    Gobi Thillainadesan
    Department of Oncology, London Regional Cancer Program and The Lawson Health Research Institute, London, Ontario, Canada
    Mol Cell Biol 28:6066-77. 2008

Collaborators

  • Pierre Chambon
  • Gobi Thillainadesan
  • Joseph Torchia
  • Hina Naeem
  • Ryan D Mohan
  • Majdina Isovic
  • Joseph Andrews
  • Esther Loney
  • Anita Rao
  • Qingshi Zhao
  • Caroline Underhill
  • Jason Gagliardi
  • Donghang Cheng
  • Marc T Bedford

Detail Information

Publications4

  1. ncbi Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription
    Marc Tini
    Gene Expression Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Mol Cell 9:265-77. 2002
    ..These observations reveal a potential regulatory role for protein acetylation in base mismatch repair and a role for CBP/p300 in maintaining genomic stability...
  2. ncbi The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation
    Hina Naeem
    Cancer Research Laboratories, London Regional Cancer Program, London, Ontario, Canada N6A 4L6
    Mol Cell Biol 27:120-34. 2007
    ..Collectively, our data highlight coactivator methylation as an important regulatory mechanism in hormonal signaling...
  3. ncbi SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment
    Ryan D Mohan
    Department of Physiology and Pharmacology, Siebens Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6G 2V4
    Mol Cell Biol 27:229-43. 2007
    ..These findings suggest that TDG sumoylation promotes intramolecular interactions with amino- and carboxy-terminal SUMO-1 binding motifs that dramatically alter the biochemical properties and subcellular localization of TDG...
  4. ncbi Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex
    Gobi Thillainadesan
    Department of Oncology, London Regional Cancer Program and The Lawson Health Research Institute, London, Ontario, Canada
    Mol Cell Biol 28:6066-77. 2008
    ..Collectively, these results establish the ZNF217 complex as a novel negative regulator of the p15(ink4b) gene and may constitute an important link between amplification of ZNF217 and the loss of TGF-beta responsiveness in breast cancer...