Research Topics
| Colin M ShapiroSummaryAffiliation: University of Toronto Country: Canada Publications
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Detail Information
Publications
Development of an adjective checklist to measure five FACES of fatigue and sleepiness. Data from a national survey of insomniacsColin M Shapiro
Department of Psychiatry, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada
J Psychosom Res 52:467-73. 2002..The resulting five-scale FACES questionnaire appears to offer a promising self-report instrument for the measurement of fatigue and related subjective experiences...
"Sleepiness" is serious in adolescence: two surveys of 3235 Canadian studentsEdward S Gibson
Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada
BMC Public Health 6:116. 2006..of the study were to determine the level of sleepiness among students in high school, to identify factors to explain it, and to determine the association between sleepiness and performance in both academic and extracurricular activities..
Chronic fatigue: listen and measureColin M Shapiro
Department of Psychiatry, University of Toronto and University Health Network, Canada
J Psychosom Res 52:427-36. 2002
Sexsomnia--a new parasomnia?Colin M Shapiro
Sleep and Alertness Clinic, University Health Network, University of Toronto, Toronto Western Hospital, Toronto, Ontario
Can J Psychiatry 48:311-7. 2003..To describe a distinct parasomnia involving sexual behaviour, which we have named sexsomnia...
Mirtazapine, a sedating antidepressant, and improved driving safety in patients with major depressive disorder: a prospective, randomized trial of 28 patientsJianhua Shen
Sleep Research Unit, Department of Psychiatry, Toronto Western Hospital, Ontario, Canada
J Clin Psychiatry 70:370-7. 2009..The objectives of the study were to investigate the effects of mirtazapine, a sedating antidepressant, on driving safety in major depressive disorder (MDD) patients and to observe the effect of mirtazapine on daytime alertness...
Spectral modulation attenuates molecular, endocrine, and neurobehavioral disruption induced by nocturnal light exposureShadab A Rahman
Samuel Lunenfeld Research Institute, 25 Orde St, Mount Sinai Hospital, Toronto, Ontario, Canada
Am J Physiol Endocrinol Metab 300:E518-27. 2011..The current data suggest that spectral modulation may provide an effective method of regulating the effects of light on physiological processes...
Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patientsFrances Chung
Department of Anesthesia, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
Anesthesiology 108:822-30. 2008..This study was conducted to validate the Berlin questionnaire and the American Society of Anesthesiologists (ASA) checklist in surgical patients and to compare them with the STOP questionnaire...
Simulator performance, microsleep episodes, and subjective sleepiness: normative data using convergent methodologies to assess driver drowsinessHenry J Moller
Human Performance Laboratory and Sleep Research Unit, Neuropsychiatry Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
J Psychosom Res 61:335-42. 2006..Our objective was to examine a novel standardized assessment methodology of detecting impaired driving performance due to drowsiness in a normative cohort...
Excessive daytime sleepiness and fatigue in depressed patients and therapeutic response of a sedating antidepressantJianhua Shen
Sleep Research Laboratory, Department of Psychiatry, University Health Network, University of Toronto, Toronto, Ontario, Canada
J Affect Disord 134:421-6. 2011..The main objective of this study was to investigate the therapeutic effects of a sedating antidepressant on sleepiness and fatigue in patients with depression...
Positive sleep state misperception - a new concept of sleep misperceptionNikola N Trajanovic
Sleep and Alertness Clinic, University Health Network, Fell 3B 178, 399 Bathurst Street, Toronto, Ont, Canada M5T 2S8
Sleep Med 8:111-8. 2007..Overestimation of sleep has also been reported in the past, with no clear reference to corresponding polysomnographic (PSG) findings or its clinical significance...
Patients with difficult intubation may need referral to sleep clinicsFrances Chung
Department of Anesthesia, University of Toronto, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada
Anesth Analg 107:915-20. 2008..We hypothesized that patients who presented with difficult intubation would have a very high prevalence of OSA and that those with unexpected difficult intubation may require referral to sleep clinics for polysomnography (PSG)...
Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndromeShadab A Rahman
Sleep Research Laboratory, University Health Network, Toronto, Ont, Canada
Sleep Med 10:549-55. 2009..The objective of the study was to determine the sensitivity and specificity of the Dim Light Melatonin Onset (DLMO) Test in diagnosing DSPS in a clinical setting...
The Berlin questionnaire for sleep apnea in a sleep clinic population: relationship to polysomnographic measurement of respiratory disturbanceNegar Ahmadi
Department of Psychiatry, Toronto Western Hospital, ON, Canada
Sleep Breath 12:39-45. 2008..Due to the low sensitivity and specificity as well as the large number of false negatives and positives, the Berlin questionnaire is not an appropriate instrument for identifying patients with sleep apnea in a sleep clinic population...
Moderate exercise and bright light treatment in overweight and obese individualsAndrea Dunai
Sleep Research Unit, Department of Psychiatry, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada M5T 2S8
Obesity (Silver Spring) 15:1749-57. 2007..The aim of this study is to conduct a controlled investigation of the effects of bright light therapy and exercise on weight loss and body composition in overweight and obese individuals...
Antidepressant action of melatonin in the treatment of Delayed Sleep Phase SyndromeShadab A Rahman
Sleep Research Laboratory, University Health Network, Toronto, Ont, Canada
Sleep Med 11:131-6. 2010..This study used a randomized, double-blind, crossover, placebo-controlled approach to test the hypothesis that exogenous melatonin (5mg) can attenuate depressive symptomatology in DSPS patients...
Sleepiness is not the inverse of alertness: evidence from four sleep disorder patient groupsHenry J Moller
Sleep Research Unit, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, ON, Canada, M5T 2S8
Exp Brain Res 173:258-66. 2006..The specific primary sleep disorder diagnosis may play a relevant role in mitigating this interrelationship...
Sleep-disordered breathing, cardiac arrhythmia, and panic disorderNikola N Trajanovic
University Health Network, Toronto, Canada
J Clin Sleep Med 1:288-9. 2005..Such presentation may lead to suboptimal diagnostic and therapeutic decisions. The authors present a case in which a patient's condition improved only after the primary disorder was diagnosed and properly managed...
A new approach to the construct of alertnessColin M Shapiro
Sleep and Alertness Clinic, University Health Network, Toronto, Canada
J Psychosom Res 60:595-603. 2006....
STOP questionnaire: a tool to screen patients for obstructive sleep apneaFrances Chung
Department of Psychiatry, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
Anesthesiology 108:812-21. 2008..However, no screening tool for OSA has been validated in surgical patients. This study was conducted to develop and validate a concise and easy-to-use questionnaire for OSA screening in surgical patients...
Clinical diagnosis of sleep apnea based on single night of polysomnography vs. two nights of polysomnographyNegar Ahmadi
Sleep Research Unit, Toronto Western Research Institute, University Health Network, ON, Canada
Sleep Breath 13:221-6. 2009..The purpose of this study was to investigate apnea-hypopnea index (AHI) across two polysomnographies (PSGs) to examine AHI variability and impact on clinical diagnosis...
Oxygen desaturation index from nocturnal oximetry: a sensitive and specific tool to detect sleep-disordered breathing in surgical patientsFrances Chung
FRCPC, Department of Anesthesia, University Health Network, University of Toronto, 399, Bathurst Street, Toronto, ON, Canada M5T 2S8
Anesth Analg 114:993-1000. 2012..It is impractical to perform polysomnography (PSG) in all surgical patients suspected of having sleep disordered breathing (SDB). We investigated the role of nocturnal oximetry in diagnosing SDB in surgical patients...
Measurements of sleepiness and fatigueAzmeh Shahid
Department of Psychiatry, University Health Network, University of Toronto, Toronto, Canada
J Psychosom Res 69:81-9. 2010..Establishing objective assessing instruments to evaluate fatigue and clarifying the relationship between objective and subjective assessments of sleepiness are crucially needed...
Acupuncture increases nocturnal melatonin secretion and reduces insomnia and anxiety: a preliminary reportD Warren Spence
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
J Neuropsychiatry Clin Neurosci 16:19-28. 2004..004) anxiety scores were also found. These objective findings are consistent with clinical reports of acupuncture's relaxant effects. Acupuncture treatment may be of value for some categories of anxious patients with insomnia...
Perioperative practical experiences in using a level 2 portable polysomnographyFrances Chung
Department of Anesthesia, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, ON, Canada
Sleep Breath 15:367-75. 2011..The objective of the study is to test the hypothesis that a level 2 portable sleep device (Embletta X100) is a reliable alternative for standard PSG in surgical patients...
Polysomnographic and symptomatological analyses of major depressive disorder patients treated with mirtazapineJianhua Shen
Department of Psychiatry, University Health Network, University of Toronto, Toronto, Ontario
Can J Psychiatry 51:27-34. 2006....
Sexual behaviour in sleep: an internet surveyNikola N Trajanovic
Sleep and Alertness Clinic, University Health Network, Toronto, ON, Canada
Soc Psychiatry Psychiatr Epidemiol 42:1024-31. 2007....
Impact of orthodontic appliances on sleep qualityAkbar Rawji
Bowmanville and Oshawa, Ontario, Canada
Am J Orthod Dentofacial Orthop 134:606-14. 2008..Many young patients are asked to wear headgear or functional appliances during sleep as part of their orthodontic treatment. The objective of this clinical study was to assess the impact of these appliances on sleep quality...
Distinguishing sleepiness and fatigue: focus on definition and measurementJianhua Shen
Sleep Research Laboratory, Department of Psychiatry, University Health Network and University of Toronto, 399 Bathurst Street, 7M 417, Toronto, Ont, Canada M5T 2S8
Sleep Med Rev 10:63-76. 2006..Despite a high prevalence and high degree of morbidity, fatigue has remained a relatively under appreciated symptom, from both a clinical and research point of view...
Evaluation and treatment of sleep complaints: patients' subjective responsesNaheed K Hossain
Sleep and Alertness Clinic, Department of Psychiatry, Toronto Western Hospital, Toronto, Canada
Psychother Psychosom 76:395-9. 2007..This study set out to evaluate whether patients' expectations affected their responses to treatment of a sleep disorder...
Fatigue and shift workJianhua Shen
Department of Psychiatry, University Health Network, University of Toronto, Toronto, ON, Canada
J Sleep Res 15:1-5. 2006..Future research should address the possibility of using the FSS as an indicator when the frequency of shift work has become high enough to adversely affect work performance or cause health problems...
What is the driving performance of ambulatory surgical patients after general anesthesia?Frances Chung
Department of Anesthesia, Toronto Western Hospital, University of Toronto, Ontario, Canada
Anesthesiology 103:951-6. 2005..The purpose of this study was to determine whether impaired driver alertness had been restored to normal by 2 and 24 h after general anesthesia in patients who underwent ambulatory surgery...
Factors that influence CPAP adherence: an overviewGilla K Shapiro
Youthdale Child and Adolescent Sleep, 227 Victoria St, Lower Level 2, Toronto, ON, M5B 1T8, Canada
Sleep Breath 14:323-35. 2010..However, nonadherence is a significant contributor to the growing burden of untreated OSAS, and is associated with negative consequences for the patient, public safety, and the healthcare system...
Effect of sleeping in a head-up position on intraocular pressure in patients with glaucomaYvonne M Buys
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada
Ophthalmology 117:1348-51. 2010..To determine whether a 30-degree head-up sleeping position decreases nocturnal intraocular pressure (IOP) compared with lying flat in patients with glaucoma...
The effect of one versus two nights of in-laboratory continuous positive airway pressure titration on continuous positive airway pressure complianceJulia L Kaplan
Department of Psychiatry, Toronto Western Hospital, Toronto, Ontario, Canada
Behav Sleep Med 5:117-29. 2007..To investigate continuous positive airway pressure (CPAP) compliance after one versus two nights of CPAP titration...
Predictors of impaired daytime sleep and wakefulness in patients with Parkinson disease treated with older (ergot) vs newer (nonergot) dopamine agonistsAjmal Razmy
Divisions of Psychiatry and Neurology, Department of Medicine, University of Toronto, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
Arch Neurol 61:97-102. 2004..Physicians concerned with daytime hypersomnolence in PD patients treated with dopamine agonists and receiving high levodopa dosage equivalents should consider polysomnographic monitoring for impaired daytime sleep latency...
Subjective fatigue and subjective sleepiness: two independent consequences of sleep disorders?Jamil L Hossain
Sleep Research Unit and Department of Psychiatry, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
J Sleep Res 14:245-53. 2005..Furthermore, predominantly fatigued individuals with sleep disorders seem vulnerable to additional negative consequences due to possible interplay between amplified fatigue and psychological distress...
Prevention of melatonin suppression by nocturnal lighting: relevance to cancerLeonid Kayumov
Sleep Research Laboratory, University Health Network, University of Toronto, Ontario, Canada
Eur J Cancer Prev 16:357-62. 2007..Preventing melatonin deficiencies using lenses that block light of low wavelength from reaching the retina presents a cost-effective, practical solution to the problem of increased malignancy rates in shift workers...
Depressive symptomatology in tertiary-care glaucoma patientsPer O Lundmark
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont
Can J Ophthalmol 44:198-204. 2009..To investigate depressive symptomatology among patients with glaucoma and to relate the findings to disease stability...
Sleep apnea, hypertension, and the effects of continuous positive airway pressureSukhjeet Dhillon
Sleep Research Laboratory, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
Am J Hypertens 18:594-600. 2005..This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations...
Subjective and objective evaluation of sleep and performance in daytime versus nighttime sleep in extended-hours shift-workers at an underground mineJamil L Hossain
Sleep Research Laboratory and the Department of Psychiatry, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
J Occup Environ Med 46:212-26. 2004..We suggest that these benefits are mostly the result of the timing of the new nightshift start and end times rather than other shift-schedule factors...
Memory enhancement induced by hypothalamic/fornix deep brain stimulationClement Hamani
Division of Neurosurgery, Toronto Western Hospital and Research Institute, University of Toronto, Toronto, Ontario, Canada
Ann Neurol 63:119-23. 2008..This shows that hypothalamic stimulation in this patient modulates limbic activity and improves certain memory functions...
Hypocretin/Orexin: a molecular link between sleep, energy regulation, and pleasureHooman Ganjavi
University of Toronto, Toronto, Canada
J Neuropsychiatry Clin Neurosci 19:413-9. 2007..This article reviews the recent literature with regard to the many functions of this single molecule. The authors suggest that eating habits and impulsivity may be topics worth exploring in the evaluation of narcoleptic patients...
Sleep and health consequences of shift work in womenSharon A Chung
Sleep Research Unit, University of Toronto, Ontario, Canada
J Womens Health (Larchmt) 18:965-77. 2009..The literature suggests that women shift workers report poor sleep quality and experience reproductive disturbances, an increased risk of breast cancer, and a greater risk of metabolic and cardiovascular disorders...
Sleep disorders presenting as common pediatric problemsJohanna C Goll
Department of Psychiatry and Youthdale Child and Adolescent Sleep Clinic, University of Toronto, University Health Network, Toronto Western Hospital, Toronto, Ont
CMAJ 174:617-9. 2006
The effects of nefazodone on women with seasonal affective disorder: clinical and polysomnographic analysesJianhua Shen
Department of Psychiatry, University of Toronto, University Health Network, Toronto, ON
J Psychiatry Neurosci 30:11-6. 2005..To outline the clinical and polysomnographic changes induced by nefazodone in patients with seasonal affective disorder...
The prevalence, cost implications, and management of sleep disorders: an overviewJamil L Hossain
Sleep Research Laboratory, Ontario, Canada
Sleep Breath 6:85-102. 2002....
Increased utilization of health services by insomniacs--an epidemiological perspectiveMarta Novak
Department of Psychiatry, University Health Network, University of Toronto, Toronto, Canada
J Psychosom Res 56:527-36. 2004..We assessed the prevalence of sleep complaints, insomnia in particular, in a nationally representative sample of the Hungarian population and assessed health care utilization by insomniacs...
Psychiatric aspects of late-life insomniaHenry J Moller
Department of Psychiatry, Sleep and Alertness Clinic, Toronto Western Hospital, University of Toronto, 399 Bathurst St, Toronto, Ont M5T 2S8, Canada
Sleep Med Rev 8:31-45. 2004..Light therapy and behavior therapies are important in multimodal treatment of insomnia, and sleep hygiene includes both regular physical and social activities to preserve entrainment of circadian rhythms affecting sleep...
Validation of a short questionnaire in English and French for use in patients with persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy: the PASS (Proton pump inhibitor Acid Suppression Symptom) testDavid Armstrong
Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
Can J Gastroenterol 19:350-8. 2005....
REM sleep behaviour disorder in a child with Tourette's syndromeNikola N Trajanovic
Sleep and Alertness Clinic, Toronto, ON, Canada
Can J Neurol Sci 31:572-5. 2004..RESULTS: The co-existence of Tourette's syndrome and RBD was confirmed after polysomnographic studies using the standard criteria. The authors propose possible overlap in the pathophysiological mechanisms underlying the two disorders...
Diagnosis and management of insomnia in dialysis patientsMarta Novak
Institute of Behavioral Sciences, Semmelweis University, Budapest, Hungary, and Department of Nephrology, Humber River Regional Hospital, Toronto, Ontario, Canada
Semin Dial 19:25-31. 2006..Considering the polypharmacy and altered metabolism in this patient population, treatment trials are clearly needed. This article reviews the diagnosis of sleep disorders with a focus on insomnia in patients on dialysis...
Blocking low-wavelength light prevents nocturnal melatonin suppression with no adverse effect on performance during simulated shift workLeonid Kayumov
Sleep Research Laboratory, Department of Psychiatry, University Health Network, ECW 3D 035, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
J Clin Endocrinol Metab 90:2755-61. 2005..Unfiltered bright light drastically suppressed melatonin production. Normalization of endogenous melatonin production while wearing goggles did not impair measures of performance, subjective sleepiness, or alertness...
How, what, and why of sleep apnea. Perspectives for primary care physiciansSharon A Chung
Department of Psychiatry, Toronto Western Hospital, 399 Bathurst St, ECW 3D 008, Toronto, ON M5T 2S8
Can Fam Physician 48:1073-80. 2002..To review the need for primary care physicians to screen for patients with obstructive sleep apnea (OSA)...
Disturbed sleep and burnout: implications for long-term healthPhilip Saleh
J Psychosom Res 65:1-3. 2008
Psychomotor disturbance in depression: assessment using a driving simulator paradigmEric L Bulmash
Department of Clinical Psychology, Queens University, Canada
J Affect Disord 93:213-8. 2006..The goal of this investigation was to examine the association between MDD and driving ability assessed within a simulated driving paradigm...
Tenses of insomnia epidemiologyMaurice M Ohayon
J Psychosom Res 53:525-7. 2002
Chronic insomnia in kidney transplant recipientsMarta Novak
Institute of Behavioral Sciences, First Department of Internal Medicine, Semmelweis University, Budapest, Hungary
Am J Kidney Dis 47:655-65. 2006..Because this condition potentially is treatable, attention should be directed to the appropriate diagnosis and management of insomnia in the kidney transplant recipient population...
Depression and vital exhaustion before and after myocardial infarctionColin M Shapiro
J Psychosom Res 58:391-2. 2005
Diagnosis and management of sleep apnea syndrome and restless legs syndrome in dialysis patientsMarta Novak
Institute of Behavioral Sciences, Semmelweis University, Budapest, Hungary
Semin Dial 19:210-6. 2006..Appropriate management of sleep disorders could improve the quality of life and possibly even impact upon survival of renal patients...
Chronic fatigue and chronic fatigue syndrome: pathogenesis and measurement scalesColin M Shapiro
J Psychosom Res 60:549-50. 2006
Health and socioeconomic status differences among antibody hepatitis C positive and negative transfusion recipients, 1986-1990Robert S Hogg
Division of Epidemiology, British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC
Can J Public Health 94:130-4. 2003..To characterize the socioeconomic and health status, disease symptoms of anti-HCV-positive and negative transfusion recipients...
Sleep-disordered breathing and effects on ocular healthSukhjeet Dhillon
University of Waterloo, School of Optometry, Waterloo, Ont, Canada
Can J Ophthalmol 42:238-43. 2007..The importance of understanding these relationships is the positive benefits to ocular health that can derive when sleep-disordered breathing is diagnosed and treated...
Cardiovascular disease and health-care utilization in snorers: a population surveyAndrea Dunai
Institute of Behavioral Sciences, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Sleep 31:411-6. 2008..We assessed the prevalence of self-reported snoring in the Hungarian population and established whether different types of snoring are associated with cardiovascular disorders and increased health-care utilization...
Cognitive effects of long-term benzodiazepine use in older adultsMary Pat McAndrews
Department of Psychology, Toronto Western Hospital and University of Toronto, Canada
Hum Psychopharmacol 18:51-7. 2003..However, the magnitude of these effects is quite small and may be of little clinical significance in the healthy elderly...
