Research Topics
| Rob NicolsonSummaryAffiliation: University of Western Ontario Country: Canada Publications
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Detail Information
Publications
Brain magnetic resonance spectroscopy in Tourette's disorderTimothy J DeVito
Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
J Am Acad Child Adolesc Psychiatry 44:1301-8. 2005..CONCLUSIONS: The results of this study suggest compromised neuronal integrity and deficits in density of neuronal and nonneuronal cells in components of the neural circuits implicated in Tourette's disorder...- Detection and mapping of hippocampal abnormalities in autismRob Nicolson
Department of Psychiatry, The University of Western Ontario, London, Ontario, Canada
Psychiatry Res 148:11-21. 2006..The increased statistical and spatial power of computational mapping methods provided the ability to detect these differences, which were not found with traditional volumetric methods... - Three-dimensional mapping of the lateral ventricles in autismChristine N Vidal
Laboratory of Neuro Imaging, Brain Mapping Division, Department Neurology, UCLA School of Medicine, Los Angeles, California, USA
Psychiatry Res 163:106-15. 2008..These localized reductions in the lateral ventricles may result from exaggerated brain growth early in life... - Genetic and neurodevelopmental influences in autistic disorderRob Nicolson
Department of Psychiatry, University of Western Ontario, London, Ontario
Can J Psychiatry 48:526-37. 2003..However, research in the last 2 decades indicates that autism is largely caused by genetic factors that lead to abnormal brain development. This article reviews research into the genetic and neurodevelopmental factors underlying autism... - A prospective, open-label trial of galantamine in autistic disorderRob Nicolson
Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
J Child Adolesc Psychopharmacol 16:621-9. 2006..The purpose of this study was to assess the use of galantamine, an acetylcholinesterase inhibitor and nicotinic receptor modulator, in the treatment of interfering behaviors in children with autism... - White matter abnormalities in autism detected through transverse relaxation time imagingJanet Hendry
Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada
Neuroimage 29:1049-57. 2006.... - Evidence for cortical dysfunction in autism: a proton magnetic resonance spectroscopic imaging studyTimothy J DeVito
Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada
Biol Psychiatry 61:465-73. 2007..The purpose of this study was to examine cerebral gray and white matter cellular neurochemistry in autism with proton magnetic resonance spectroscopic imaging (MRSI)... - A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorderRob Nicolson
Department of Psychiatry, The University of Western Ontario, London, Ontario, Canada
J Am Acad Child Adolesc Psychiatry 44:640-6. 2005..The purpose of this study was to examine the efficacy and safety of metoclopramide in the treatment of children and adolescents with tic disorders... - Parental perception of sleep problems in children of normal intelligence with pervasive developmental disorders: prevalence, severity, and patternJennifer L Couturier
Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
J Am Acad Child Adolesc Psychiatry 44:815-22. 2005..This study compares parents' perceptions of the prevalence, severity, and pattern of sleep problems in children of normal intelligence with pervasive developmental disorders (PDDs) with a normative comparison group of children... - A retrospective assessment of citalopram in children and adolescents with pervasive developmental disordersJennifer L Couturier
Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
J Child Adolesc Psychopharmacol 12:243-8. 2002..The results of this case series suggest that citalopram has beneficial effects on some interfering behaviors associated with PDDs with few adverse effects. Controlled trials are warranted... - Mapping corpus callosum deficits in autism: an index of aberrant cortical connectivityChristine N Vidal
Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, UCLA School of Medicine, Los Angeles, California 90095-7332, USA
Biol Psychiatry 60:218-25. 2006..These abnormalities suggest aberrant connections between cortical regions, which is consistent with the hypothesis of abnormal cortical connectivity in autism... - Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophreniaChristine N Vidal
Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, David Geffen School of Medicine at UCLA, 90095-1769, USA
Arch Gen Psychiatry 63:25-34. 2006..CONCLUSION: Frontal and limbic regions may not be equally vulnerable to gray matter attrition, which is consistent with the cognitive, metabolic, and functional vulnerability of the frontal cortices in schizophrenia... - Childhood onset schizophrenia: familial neurocognitive measuresPeter A Gochman
Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3N202, Bethesda, MD 20892 1600, USA
Schizophr Res 71:43-7. 2004..Neurocognitive deficits which are seen in families of adult onset schizophrenic patients were examined in healthy family members of patients with childhood-onset schizophrenia (COS)... - Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychosesNitin Gogtay
Child Psychiatry Branch, National Institute of Mental Health NIH, Building 10, Room 3N202, 10 Center Drive, MSC 1600, Bethesda, MD 20892 1600, USA
Arch Gen Psychiatry 61:17-22. 2004..We hypothesized that cortical GM loss would occur in patients with COS but not in adolescents with atypical psychoses... - Amoxapine treatment of interfering behaviors in autistic disorderBeth Craven-Thuss
J Am Acad Child Adolesc Psychiatry 42:515-6. 2003 - Structural variation of chromosomes in autism spectrum disorderChristian R Marshall
The Centre for Applied Genomics, The Hospital for Sick Children, Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
Am J Hum Genet 82:477-88. 2008..Structural variants were found in sufficiently high frequency influencing ASD to suggest that cytogenetic and microarray analyses be considered in routine clinical workup... - Structural MRI and brain developmentPaul M Thompson
Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, California 90095-1769, USA
Int Rev Neurobiol 67:285-323. 2005