J Peter McPherson

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi Assessing the metabolic and toxic effects of anticonvulsant doses of polyunsaturated fatty acids on the liver in rats
    Ameer Y Taha
    Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, Canada
    J Toxicol Environ Health A 72:1191-200. 2009
  2. ncbi UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiation
    Helena Mistry
    Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, M5 S 1A8, Canada
    Genome Integr 1:7. 2010
  3. ncbi Essential role for Bclaf1 in lung development and immune system function
    J Peter McPherson
    Department of Pharmacology, University of Toronto, Toronto, ON, Canada
    Cell Death Differ 16:331-9. 2009
  4. ncbi In search of a function for BCLAF1
    Haya Sarras
    Department of Pharmacology and Toxicology, University of Toronto, Canada
    ScientificWorldJournal 10:1450-61. 2010
  5. ncbi A role for Mus81 in the repair of chromium-induced DNA damage
    Laura Tamblyn
    Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    Mutat Res 660:57-65. 2009
  6. ncbi A role for Brca1 in chromosome end maintenance
    J Peter McPherson
    Advanced Medical Discovery Institute, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 2C1
    Hum Mol Genet 15:831-8. 2006

Collaborators

  • M P Hande
  • Razqallah Hakem
  • Ameer Y Taha
  • Haya Sarras
  • Laura Tamblyn
  • Helena Mistry
  • Kalpana Gopalakrishnan
  • Solmaz Alizadeh Azami
  • Aileen Gracias
  • Hussein Butt
  • Daniel Sisgoreo
  • Meghan Larin
  • Prarthana Srikanth
  • Erica Li

Detail Information

Publications6

  1. ncbi Assessing the metabolic and toxic effects of anticonvulsant doses of polyunsaturated fatty acids on the liver in rats
    Ameer Y Taha
    Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, Canada
    J Toxicol Environ Health A 72:1191-200. 2009
    ..These findings suggest that PUFA, given for 3 wk at anticonvulsant doses, result in significant changes in liver lipid metabolism, but do not alter measured genetic markers of liver toxicity...
  2. ncbi UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiation
    Helena Mistry
    Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, M5 S 1A8, Canada
    Genome Integr 1:7. 2010
    ..Previous studies have demonstrated that loss of UHRF1 increases the sensitivity of cells to DNA damage however the role of UHRF1 in this response is unclear...
  3. ncbi Essential role for Bclaf1 in lung development and immune system function
    J Peter McPherson
    Department of Pharmacology, University of Toronto, Toronto, ON, Canada
    Cell Death Differ 16:331-9. 2009
    ..Our findings show a critical role for Bclaf1 in developmental processes independent of apoptosis...
  4. ncbi In search of a function for BCLAF1
    Haya Sarras
    Department of Pharmacology and Toxicology, University of Toronto, Canada
    ScientificWorldJournal 10:1450-61. 2010
    ..We also present recent findings from our laboratory and others indicating a role for BCLAF1 in post-transcriptional processes that impact mRNA metabolism, instead of a direct role for this protein in apoptosis or transcription...
  5. ncbi A role for Mus81 in the repair of chromium-induced DNA damage
    Laura Tamblyn
    Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    Mutat Res 660:57-65. 2009
    ..Our findings support a role for Mus81 in the resolution of replication-associated DNA damage associated with this genotoxic agent, by converting Cr[VI]-DNA lesions into a form more amenable for homologous recombination...
  6. ncbi A role for Brca1 in chromosome end maintenance
    J Peter McPherson
    Advanced Medical Discovery Institute, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 2C1
    Hum Mol Genet 15:831-8. 2006
    ..The telomere dysfunction phenotype in Brca1-deficient cells suggests that loss of telomere integrity might contribute to chromosome end dysfunction and permit the formation of potentially oncogenic translocations...