Research Topics
| P A McFarlaneSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
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Detail Information
Publications
Cost savings of home nocturnal versus conventional in-center hemodialysisPhilip A McFarlane
Home Dialysis, St Michael s Hospital, Toronto, Ontario, Canada
Kidney Int 62:2216-22. 2002..We hypothesized that HNHD would provide more dialysis treatments at a lower total cost than IHD...
Nocturnal hemodialysis: effects on solute clearance, quality of life, and patient survivalPhilip A McFarlane
Division of Nephrology, University of Toronto and Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada
Curr Opin Nephrol Hypertens 20:182-8. 2011..This review will examine how long nocturnal treatments have impact on the clearance of small and larger retention products, and how these treatments influence quality of life and survival...
Should patients remain on intensive hemodialysis rather than choosing to receive a kidney transplant?Philip A McFarlane
Division of Nephrology, St Michael s Hospital, Toronto, Ontario, Canada
Semin Dial 23:516-9. 2010..Clinicians should explore the reasons behind such a decision to ensure that the patient is properly informed; however, appropriately reasoned decisions should be respected...
International trends in erythropoietin use and hemoglobin levels in hemodialysis patientsPhilip A McFarlane
Division of Nephrology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Kidney Int 78:215-23. 2010..Thus, our study found that prescribing higher doses of ESAs and achieving higher hemoglobin levels by physicians reflects a broad trend across DOPPS countries regardless of the reimbursement policies...
More of the same: improving outcomes through intensive hemodialysisPhilip A McFarlane
St Michael s Hospital, Toronto, Ontario, Canada
Semin Dial 22:598-602. 2009..Future research will help to define the optimal treatment duration and frequency in hemodialysis patients...
Lessons for dialysis investigators from the Steno-2 StudyPhilip A McFarlane
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Canada
J Nephrol 21:6-13. 2008..Despite the limitations, the Steno-2 design should currently be an attractive option for dialysis investigators...
A change from subcutaneous to intravenous erythropoietin increases the cost of anemia therapyPhilip A McFarlane
Home Dialysis, St Michael s Hospital, Toronto, Ontario, Canada
Nephron Clin Pract 107:c90-6. 2007..Concerns about pure red cell aplasia led our program to switch from SC to IV EPO, so we studied the impact of this change on the cost of anemia therapy...
Estimating preference scores in conventional and home nocturnal hemodialysis patientsPhilip A McFarlane
Home Dialysis, Inner City Health Research Unit, St Michael s Hospital, Toronto, Ontario, Canada
Clin J Am Soc Nephrol 2:477-83. 2007..The operational performance of SG was good in this study, whereas biases and methodologic concerns were identified with the TTO and WTP in this population...
Improving outcomes in diabetes and chronic kidney disease: the basis for Canadian guidelinesPhilip A McFarlane
St Michael s Hospital, Toronto, Ontario
Can J Cardiol 23:585-90. 2007..In the present article, the studies that have influenced these Canadian guidelines are examined, and areas in which further research is still required are identified...
Economic considerations in frequent home hemodialysisPhil McFarlane
Department of Medicine, St Michael s Hospital Division of Nephrology, University of Toronto, Toronto, Canada
Semin Dial 24:678-83. 2011..Modifications to conventional dialysis funding are needed to accommodate for the additional costs of supplies and technology needed to support intensive modalities...
The quality of life and cost utility of home nocturnal and conventional in-center hemodialysisPhilip A McFarlane
Department of Medicine, Home Dialysis Clinic, Inner City Health Research Unit, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Kidney Int 64:1004-11. 2003..We hypothesized that individuals performing home nocturnal hemodialysis would have a higher quality of life and superior cost utility than in-center hemodialysis patients...
The impact of home nocturnal hemodialysis on end-stage renal disease therapies: a decision analysisP A McFarlane
St Michael s Hospital, 61 Queen Street East, 9th Floor, Toronto, Ontario, Canada M5C 2T2
Kidney Int 69:798-805. 2006..Our model suggests that HNHD improves quality-adjusted survival over IHD at an economically attractive cost-effectiveness ratio...
Acceptance and rejection: cost-effectiveness and the working nephrologistPhilip A McFarlane
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Kidney Int 66:1735-41. 2004....
Reducing hemodialysis costs: conventional and quotidian home hemodialysis in CanadaPhilip A McFarlane
St Michael s Hospital, 61 Queen Street East, 9th Floor, Toronto, Ontario, Canada M5C 2T2
Semin Dial 17:118-24. 2004..Home conventional hemodialysis is less expensive than in-center hemodialysis. Much of these savings are lost when dialysis frequency increases; however, quotidian home hemodialysis remains less expensive than in-center hemodialysis...
Pharyngeal narrowing in end-stage renal disease: implications for obstructive sleep apnoeaJ M Beecroft
Department of Medicine, University of Calgary, Calgary, AB, Canada
Eur Respir J 30:965-71. 2007..In conclusion, since a narrower upper airway predisposes to upper airway occlusion during sleep, it is suggested that this factor contributes to the pathogenesis of sleep apnoea in dialysis-dependent patients...
Interpreting cost-effectiveness in dialysis: can the most expensive be more expensive?P A McFarlane
Department of Medicine, University of Toronto, Toronto, Canada
Kidney Int 69:2120-1. 2006....
Treatment gaps in the management of cardiovascular risk factors in patients with type 2 diabetes in CanadaManoela Braga
Keenan Research Center, Li Ka Shing Knowledge Institute at St Michael s Hospital, University of Toronto, ON, Canada
Can J Cardiol 26:297-302. 2010..To evaluate vascular protection treatment patterns and attainment of the 2003 Canadian Diabetes Association's recommended targets in ambulatory patients with type 2 diabetes...
Glutathione and riboflavin status in supplemented patients undergoing home nocturnal hemodialysis versus standard hemodialysisJovil Kannampuzha
The Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital Toronto, Ontario, Canada Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
J Ren Nutr 20:199-208. 2010..Glutathione (GSH), an important intracellular antioxidant, requires cysteine as a rate-limiting amino acid for its synthesis and riboflavin for its regeneration...
A numerical scale comparison of renal transplant recipient experience with and opinions about calcineurin inhibitorsG V Ramesh Prasad
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Ont, Canada
Nephron Clin Pract 97:c35-40. 2004..Many studies compare the relative benefits of cyclosporine and tacrolimus with respect to graft and patient outcomes, but comparative renal transplant recipient opinion on calcineurin inhibitor (CI) use has not been directly sought...
A simple method to create buttonhole cannulation tracks in a busy hemodialysis unitRosa M Marticorena
St Michael s Hospital, Toronto, Ontario, Canada
Hemodial Int 13:316-21. 2009..Initial cannulation of the fistula using a Clampcath hemodialysis needle, leaving the polyurethane catheter indwelling for 10 days, is a simple, safe, and effective technique for the creation of buttonhole tunnel tracks...
Renal transplant recipient attitudes toward steroid use and steroid withdrawalG V Ramesh Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
Clin Transplant 17:135-9. 2003..Demographic data may be used to predict prednisone-related side-effects and guide steroid use in this population. Study designs related to steroid withdrawal should account for patient preferences in this context...
Intensified hemodialysis regimens: neglected treatment options for children and adolescentsDominik Muller
Department of Pediatric Nephrology, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
Pediatr Nephrol 23:1729-36. 2008....
