Research Topics
| Kenneth LoSummaryAffiliation: University of British Columbia Country: Canada Publications
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Detail Information
Publications
Flexible empirical Bayes models for differential gene expressionKenneth Lo
Department of Statistics, University of British Columbia, 333 6356 Agricultural Road, Vancouver, BC, Canada V6T 1Z2
Bioinformatics 23:328-35. 2007..However, to facilitate inference, some unrealistic assumptions have been made. One such assumption is that of a common coefficient of variation across genes, which can adversely affect the resulting inference...
Automated gating of flow cytometry data via robust model-based clusteringKenneth Lo
Department of Statistics, University of British Columbia, Vancouver, British Columbia V6T 1Z2, Canada
Cytometry A 73:321-32. 2008..It tends to give more reproducible results, and helps reduce the significant subjectivity and human time cost encountered in manual gating analysis...
flowClust: a Bioconductor package for automated gating of flow cytometry dataKenneth Lo
Department of Statistics, University of British Columbia, 333 6356 Agricultural Road, Vancouver, BC, V6T1Z2, Canada
BMC Bioinformatics 10:145. 2009..This is a time-consuming task that ignores the high-dimensionality of FCM data...
B cells with high side scatter parameter by flow cytometry correlate with inferior survival in diffuse large B-cell lymphomaAli Bashashati
Terry Fox Laboratory, British Columbia Cancer Agency, 675 W 10th Ave, Vancouver, BC V5Z 1L3, Canada
Am J Clin Pathol 137:805-14. 2012..This is of particular interest because this biomarker is readily available in most clinical laboratories without significant alteration to existing routine diagnostic strategies or incurring additional costs...
A pipeline for automated analysis of flow cytometry data: preliminary results on lymphoma sub-type diagnosisAli Bashashati
British Columbia Cancer Research Center, Vancouver, Canada
Conf Proc IEEE Eng Med Biol Soc 2009:4945-8. 2009..Preliminary results show more than 90% accuracy in differentiating between some sub-types of lymphoma. The proposed pipeline also finds biologically meaningful biomarkers that differ between lymphoma subtypes...
