Linda A Larcombe

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. ncbi Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA
    Linda A Larcombe
    Department of Anthropology, University of Manitoba, 435 Fletcher Argue Bldg, Winnipeg, Manitoba, Canada R3T 5V5
    Infect Genet Evol 5:117-22. 2005
  2. ncbi Differential cytokine genotype frequencies among Canadian Aboriginal and Caucasian populations
    L Larcombe
    Department of Anthropology, University of Manitoba, 435 Fletcher Argue Bldg Winnipeg, Manitoba, Canada
    Genes Immun 6:140-4. 2005
  3. ncbi Functional gene polymorphisms in canadian aboriginal populations with high rates of tuberculosis
    Linda A Larcombe
    Department of Medical Microbiology, University of Manitoba, Manitoba, Canada
    J Infect Dis 198:1175-9. 2008

Detail Information

Publications3

  1. ncbi Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA
    Linda A Larcombe
    Department of Anthropology, University of Manitoba, 435 Fletcher Argue Bldg, Winnipeg, Manitoba, Canada R3T 5V5
    Infect Genet Evol 5:117-22. 2005
    ..The analysis of cytokine SNPs of ancient nuclear DNA may provide novel insights into the genetic basis of autoimmune diseases and the susceptibility/resistance to infectious agents...
  2. ncbi Differential cytokine genotype frequencies among Canadian Aboriginal and Caucasian populations
    L Larcombe
    Department of Anthropology, University of Manitoba, 435 Fletcher Argue Bldg Winnipeg, Manitoba, Canada
    Genes Immun 6:140-4. 2005
    ..We postulate that the evolution of this unique cytokine genotype profile may be linked to the Aboriginal adaptation to selection pressures related to an environment in which helminthic, parasitic and fungal infections predominated...
  3. ncbi Functional gene polymorphisms in canadian aboriginal populations with high rates of tuberculosis
    Linda A Larcombe
    Department of Medical Microbiology, University of Manitoba, Manitoba, Canada
    J Infect Dis 198:1175-9. 2008
    ..tuberculosis and the opposing role of MCP-1 and IL-6, the observed allelic variation by ethnicity may in part contribute to the high rates of tuberculosis among the Dené...