Research Topics
| Samantha KimballSummaryAffiliation: University of Toronto Location: Toronto, Canada Publications
| Collaborators
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Detail Information
Publications
Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patientsReinhold Vieth
Department of Laboratory Medicine and Pathology, University of Toronto, Canada
Nutr J 3:8. 2004..For adults, vitamin D intake of 100 mcg (4000 IU)/day is physiologic and safe. The adequate intake (AI) for older adults is 15 mcg (600 IU)/day, but there has been no report focusing on use of this dose...
Cholecalciferol plus calcium suppresses abnormal PBMC reactivity in patients with multiple sclerosisSamantha Kimball
Departments of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
J Clin Endocrinol Metab 96:2826-34. 2011..The active metabolite of vitamin D, 1,25-dihydroxyvitamin D [1,25(OH)(2)D], is a potent modulator of immune cells in vitro...
The ratio of serum 24,25-dihydroxyvitamin D(3) to 25-hydroxyvitamin D(3) is predictive of 25-hydroxyvitamin D(3) response to vitamin D(3) supplementationDennis Wagner
Department of Nutritional Sciences, University of Toronto, Canada
J Steroid Biochem Mol Biol 126:72-7. 2011..The 24,25:25VD(3) ratio may therefore have clinical utility as a marker for VD(3) catabolism and a predictor of serum 25VD(3) response to VD(3) supplementation...
Urinary calcium response to high dose vitamin D3 with calcium supplementation in patients with multiple sclerosisSamantha M Kimball
University of Toronto, Department of Nutritional Sciences and Mount Sinai Hospital, Department of Pathology and Laboratory Medicine, Toronto, ON, Canada M5G 1X5
Clin Biochem 44:930-2. 2011..To characterize the effect of vitamin D(3) intake on urinary calcium:creatinine ratios across predefined ranges of serum 25(OH)D...
A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosisJ M Burton
Division of Neurology, St Michael s Hospital, Toronto, Canada
Neurology 74:1852-9. 2010..Our aim was to assess the tolerability of high-dose oral vitamin D and its impact on biochemical, immunologic, and clinical outcomes in patients with MS prospectively...
Vitamin D and multiple sclerosis hospital admissions in ScotlandG Disanto
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford, OX3 7BN, UK
QJM 104:1001-3. 2011
Short- and long-term safety of weekly high-dose vitamin D3 supplementation in school childrenJoyce Maalouf
Calcium Metabolism and Osteoporosis Program, American University of Beirut Medical Center, Bliss Street, Beirut, Lebanon
J Clin Endocrinol Metab 93:2693-701. 2008..Hypovitaminosis D is prevalent in youth worldwide, but the safety of vitamin D at doses exceeding 200 IU/d is unknown in this age group. We assessed the safety of high doses of vitamin D(3) administered to apparently healthy schoolchildren...
Self-prescribed high-dose vitamin D3: effects on biochemical parameters in two menSamantha Kimball
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Ann Clin Biochem 45:106-10. 2008..Close monitoring of biochemical responses confirmed that an increase in urinary calcium:creatinine ratio precedes hypercalcaemia as serum 25(OH)D concentrations rise...
A comparison of automated methods for the quantitation of serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin DSamantha M Kimball
Department of Nutritional Sciences, University of Toronto, Department of Laboratory Medicine and Pathology, Mt Sinai Hospital, Ontario, Canada
Clin Biochem 40:1305-10. 2007..To compare automated platforms with the routinely used methods in our clinical laboratory for the quantitation of 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D]...
Safety of vitamin D3 in adults with multiple sclerosisSamantha M Kimball
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Am J Clin Nutr 86:645-51. 2007....
Vitamin D: a growing perspectiveSamantha Kimball
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Crit Rev Clin Lab Sci 45:339-414. 2008..Here we review the available data concerning vitamin D status and health effects of vitamin D in pregnancy through to and including adolescence...
