Paul J Karanicolas

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Mesenteric angiography for the localization and treatment of acute lower gastrointestinal bleeding
    Paul J Karanicolas
    Department of Surgery, University of Western Ontario, and University Hospital, London, Ontario
    Can J Surg 51:437-41. 2008
  2. ncbi The more the better?: the impact of surgeon and hospital volume on in-hospital mortality following colorectal resection
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Ann Surg 249:954-9. 2009
  3. ncbi The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
    Ann Surg Oncol 14:1825-34. 2007
  4. ncbi The cost of laparoscopic myotomy versus pneumatic dilatation for esophageal achalasia
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Surg Endosc 21:1198-206. 2007
  5. ncbi Interobserver reliability of classification systems to rate the quality of femoral neck fracture reduction
    Paul J Karanicolas
    Department of Surgery, London Health Sciences Centre, London, Canada
    J Orthop Trauma 23:408-12. 2009
  6. ncbi The impact of prophylactic dexamethasone on nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis
    Paul J Karanicolas
    Department of Surgery, University of Western Ontario, London, Canada
    Ann Surg 248:751-62. 2008
  7. ncbi Radiographs of hip fractures were digitally altered to mask surgeons to the type of implant without compromising the reliability of quality ratings or making the rating process more difficult
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, University Hospital, Room C8 114, 339 Windermere Rd, London, Ontario N6A 5A5, Canada
    J Clin Epidemiol 62:214-223.e1. 2009
  8. ncbi Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
    Dirk Bassler
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 303:1180-7. 2010
  9. ncbi Treatment of displaced femoral neck fractures in the elderly: a cost-benefit analysis
    Bashar Alolabi
    Department of Surgery, University of Western Ontario, Ontario, Canada
    J Orthop Trauma 23:442-6. 2009
  10. ncbi The development of a decision aid to elicit treatment preferences for displaced femoral neck fractures
    Bashar Alolabi
    Department of Surgery, The University of Western Ontario, London, Ontario, Canada
    Indian J Orthop 46:22-8. 2012

Collaborators

Detail Information

Publications21

  1. ncbi Mesenteric angiography for the localization and treatment of acute lower gastrointestinal bleeding
    Paul J Karanicolas
    Department of Surgery, University of Western Ontario, and University Hospital, London, Ontario
    Can J Surg 51:437-41. 2008
    ..Our objective was to determine the complications and outcomes of mesenteric angiography in patients with ALGIB and to identify predictors of a positive result at angiography...
  2. ncbi The more the better?: the impact of surgeon and hospital volume on in-hospital mortality following colorectal resection
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Ann Surg 249:954-9. 2009
    ....
  3. ncbi The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
    Ann Surg Oncol 14:1825-34. 2007
    ..Our objective was to determine the relative effects of pylorus-preserving pancreaticoduodenectomy (PPPD) and standard Whipple pancreaticoduodenectomy (SWPD) in patients with pancreatic or periampullary cancer...
  4. ncbi The cost of laparoscopic myotomy versus pneumatic dilatation for esophageal achalasia
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Surg Endosc 21:1198-206. 2007
    ..The two main treatment options for esophageal achalasia are laparoscopic distal esophageal myotomy (LM) and pneumatic dilatation (PD). Our objective was to compare the costs of these management strategies...
  5. ncbi Interobserver reliability of classification systems to rate the quality of femoral neck fracture reduction
    Paul J Karanicolas
    Department of Surgery, London Health Sciences Centre, London, Canada
    J Orthop Trauma 23:408-12. 2009
    ..We compared the interrater reliability of five classification systems and surgeons' global impressions of the quality of femoral neck fracture reduction...
  6. ncbi The impact of prophylactic dexamethasone on nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis
    Paul J Karanicolas
    Department of Surgery, University of Western Ontario, London, Canada
    Ann Surg 248:751-62. 2008
    ..To determine the impact of prophylactic corticosteroid administration on postoperative nausea, vomiting, pain and complications in patients undergoing laparoscopic cholecystectomy...
  7. ncbi Radiographs of hip fractures were digitally altered to mask surgeons to the type of implant without compromising the reliability of quality ratings or making the rating process more difficult
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, University Hospital, Room C8 114, 339 Windermere Rd, London, Ontario N6A 5A5, Canada
    J Clin Epidemiol 62:214-223.e1. 2009
    ..To devise and test techniques to blind outcome assessors in trials of hip fracture fixation...
  8. ncbi Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
    Dirk Bassler
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 303:1180-7. 2010
    ..Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping...
  9. ncbi Treatment of displaced femoral neck fractures in the elderly: a cost-benefit analysis
    Bashar Alolabi
    Department of Surgery, University of Western Ontario, Ontario, Canada
    J Orthop Trauma 23:442-6. 2009
    ..Compared with hemiarthroplasty (HA), internal fixation (IF) is associated with less operative trauma, bleeding, and possibly lower mortality at the expense of a higher reoperation rate and possibly increased cost...
  10. ncbi The development of a decision aid to elicit treatment preferences for displaced femoral neck fractures
    Bashar Alolabi
    Department of Surgery, The University of Western Ontario, London, Ontario, Canada
    Indian J Orthop 46:22-8. 2012
    ..There is a lack of use of decision aids in the orthopedic literature. The purpose of this study was to develop a decision board to elicit preferences for treatment of displaced femoral neck fractures in patients over 60 years old...
  11. ncbi Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  12. ncbi Arthroplasty versus internal fixation of femoral neck fractures: a clinical decision analysis
    Ilyas S Aleem
    Departments of Surgery, McMaster University, Hamilton, Ontario, Canada
    Ortop Traumatol Rehabil 11:233-41. 2009
    ..We sought to compare arthroplasty and internal fixation alternatives and determine the key factors influencing final outcomes using a clinical decision analysis...
  13. ncbi Evaluating agreement: conducting a reliability study
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 293 Wellington Street North, Suite 110, Hamilton, ON L8L 2X2, Canada
    J Bone Joint Surg Am 91:99-106. 2009
    ..Readers interested in critically appraising reliability studies or in developing their own reliability studies may find this review helpful...
  14. ncbi Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, ON, Canada
    BMJ 338:b92. 2009
    ....
  15. ncbi A new 'mechanistic-practical" framework for designing and interpreting randomized trials
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada
    J Clin Epidemiol 62:479-84. 2009
    ..e., the conventional pragmatic trial. Instead we will design, implement, and apply the results of practical trials to our patients...
  16. ncbi Hemodynamic performance of stentless versus stented valves: a systematic review and meta-analysis
    Darrin M Payne
    London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    J Card Surg 23:556-64. 2008
    ..The goal of this review was to systematically locate, critically appraise, and quantitatively combine results to determine if stentless valves improve cardiac hemodynamics...
  17. ncbi Blinding of outcomes in trials of orthopaedic trauma: an opportunity to enhance the validity of clinical trials
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    J Bone Joint Surg Am 90:1026-33. 2008
    ..Trials of surgical interventions present blinding challenges not seen in drug trials. How often orthopaedic trauma investigators undertake blinding, and the frequency with which they could potentially utilize blinding, remains uncertain...
  18. ncbi Better late than never? Impact of local analgesia timing on postoperative pain in laparoscopic surgery: a systematic review and metaanalysis
    Shaun M Coughlin
    Department of Surgery, University of Western Ontario, London, ON, Canada
    Surg Endosc 24:3167-76. 2010
    ..This study aimed to determine the effect of local anesthesia administered before laparoscopic surgery (preemptive anesthesia) on postoperative pain...
  19. ncbi Surgical preferences of patients at risk of hip fractures: hemiarthroplasty versus total hip arthroplasty
    Noor Alolabi
    Division of Orthopaedic Surgery, McMaster University, Hamilton, Canada
    BMC Musculoskelet Disord 12:289. 2011
    ..The purpose of this study was to elicit surgical preferences of patients at risk of sustaining hip fracture using a novel decision board...
  20. ncbi Randomized controlled trials of surgical interventions
    Forough Farrokhyar
    Department of Surgery, McMaster University, Hamilton, Ontario, Canada
    Ann Surg 251:409-16. 2010
    ..Surgical trials pose many methodological challenges often not present in trials of medical interventions. If not properly accounted for, these challenges may introduce significant biases and threaten the validity of the results...
  21. ncbi The fastest route between two points is not always a straight line: An analysis of air and land transfer of nonpenetrating trauma patients
    Paul J Karanicolas
    Department of Surgery, London Health Sciences Centre, London, Ontario, Canada
    J Trauma 61:396-403. 2006
    ....