Research Topics
| Mojgan HodaieSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
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Detail Information
Publications
Involvement of the basal ganglia and cerebellar motor pathways in the preparation of self-initiated and externally triggered movements in humansJamie Purzner
The Krembil Neuroscience Centre and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada M5T 2S8
J Neurosci 27:6029-36. 2007..The CTC pathway is involved in the preparation of self-paced but not externally cued movements, although the pathway may still be involved in the execution of these movements...- Tractography delineates microstructural changes in the trigeminal nerve after focal radiosurgery for trigeminal neuralgiaMojgan Hodaie
Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
PLoS ONE 7:e32745. 2012..Changes in specific diffusivities may provide insight into the mechanism of action of radiosurgery on the trigeminal nerve... - In vivo visualization of cranial nerve pathways in humans using diffusion-based tractographyMojgan Hodaie
Division of Neurosurgery, University of Toronto and Toronto Western Hospital, Toronto, Canada
Neurosurgery 66:788-95; discussion 795-6. 2010..In particular, the feasibility of tractography of the individual cranial nerves has not been previously assessed... - The dopaminergic nigrostriatal system and Parkinson's disease: molecular events in development, disease, and cell death, and new therapeutic strategiesMojgan Hodaie
Division of Neurosurgery, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Canada
Neurosurgery 60:17-28; discussion 28-30. 2007..These advancements are used as a template to review emerging therapeutic techniques, including neuroprotection strategies, surgical treatment of trophic factors, gene therapy, and neural transplantation... - Spinal cord stimulators and radiotherapy: first case report and practice guidelinesLorraine Walsh
Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto M5G2M9, Ontario, Canada
Radiat Oncol 6:143. 2011..We also provide useful practical recommendations on the management of this scenario within a radiation oncology department... - Dopamine-dependent high-frequency oscillatory activity in thalamus and subthalamic nucleus of patients with Parkinson's diseaseAbdoul Kane
Department of Physiology, University of Toronto, Toronto, Ontario, Canada
Neuroreport 20:1549-53. 2009..These findings confirm and extend earlier findings suggesting that in PD there are marked changes in basal ganglia oscillatory activity and that these can be reversed after dopaminergic therapy... - High-frequency microstimulation in human globus pallidus and substantia nigraMyriam Lafreniere-Roula
Department of Physiology, University of Toronto, Medical Sciences Building Room 3302, 1 King s College Circle, Toronto, ON, M5S 1A8, Canada
Exp Brain Res 205:251-61. 2010..The findings suggest that high-frequency microstimulation of the GPi and SNr depresses local neuronal activity and synaptic transmission, and such mechanisms may contribute to the therapeutic effects of DBS... - Movement related potentials and oscillatory activities in the human internal globus pallidus during voluntary movementsEric W Tsang
Division of Brain Imaging and Behaviour Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Canada
J Neurol Neurosurg Psychiatry 83:91-7. 2012..To study internal globus pallidus (GPi) activities and the interactions among the bilateral GPi and motor cortical areas during voluntary movements... - Oscillatory activity in the globus pallidus internus: comparison between Parkinson's disease and dystoniaMoran Weinberger
Department of Physiology, University of Toronto, Toronto, ON, Canada
Clin Neurophysiol 123:358-68. 2012.... - Microstimulation-induced inhibition as a tool to aid targeting the ventral border of the subthalamic nucleusMyriam Lafreniere-Roula
Department of Physiology, University of Toronto, Ontario, Canada
J Neurosurg 111:724-8. 2009..The presence of inhibition in the SNr but not in the STN could be used as an additional criterion to help identify the location of the border between the STN and SNr... - Deep brain stimulation of the ventral intermediate nucleus of the thalamus for tremor in patients with multiple sclerosisCristina V Torres
Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, Ontario, Canada
Neurosurgery 67:646-51; discussion 651. 2010..Tremor is an important cause of disability in patients with multiple sclerosis (MS). Deep brain stimulation (DBS) in the ventral intermediate nucleus (VIM) of the thalamus is said to be beneficial for MS tremor... - The nature and time course of cortical activation following subthalamic stimulation in Parkinson's diseaseRenju Kuriakose
Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5T 2S8
Cereb Cortex 20:1926-36. 2010..Cortical activation may be related to the clinical effects of STN DBS in PD... - The dominant-STN phenomenon in bilateral STN DBS for Parkinson's diseaseAnna Castrioto
Movement Disorders Center, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, ON, Canada
Neurobiol Dis 41:131-7. 2011..In our sample 50% of the patients presented with a dominant-STN, suggesting that a non-negligible part of PD patients might not need bilateral STN-DBS surgery... - Anterior thalamus deep brain stimulation at high current impairs memory in ratsClement Hamani
Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada
Exp Neurol 225:154-62. 2010..Though translating data from animals to humans has to be considered with caution, our study underscores the need for carefully monitoring memory function while selecting stimulation parameters during the clinical evaluation of AN DBS... - Enhanced synchronization of thalamic theta band local field potentials in patients with essential tremorAbdoul Kane
Department of Physiology, University of Toronto, Toronto, ON, Canada
Exp Neurol 217:171-6. 2009.... - Unilateral pallidal deep brain stimulation in a patient with cervical dystonia and tremorCristina V Torres
Division of Neurosurgery, Department of Surgery, Movement Disorders Center, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, Ontario, Canada
J Neurosurg 113:1230-3. 2010..The authors report on a case of unilateral GPi implantation that resulted in sustained benefit with marked improvement in pain and dystonia... - Deep brain stimulation for the treatment of epilepsyClement Hamani
Division of Neurosurgery Toronto Western Hospital University of Toronto, Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada
Int J Neural Syst 19:213-26. 2009..We review the published literature on DBS, cortical and cerebellar stimulation for the treatment of epilepsy focusing predominantly on the rationale and clinical outcome in each target... - Clinical evaluation of stereotactic target localization using 3-Tesla MRI for radiosurgery planningDerek MacFadden
University of Toronto Faculty of Medicine, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 76:1472-9. 2010..The objectives of the present study were to spatially investigate the effect of 3-Tesla (3T) MRI on clinical target localization for stereotactic radiosurgery... - Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractographyDavid Qixiang Chen
Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
Neurosurgery 68:1077-83. 2011..However, imaging of the CN fibers surrounding vestibular schwannomas has been limited with 2-dimensional imaging alone... - Saccade-related potentials recorded from human subthalamic nucleusAdrian P Fawcett
Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ont, Canada
Clin Neurophysiol 118:155-63. 2007..To investigate an ocular motor role for the STN in Parkinson's disease (PD) patients... - Complications of Gamma Knife surgery: an early report from 2 Canadian centersShobhan Vachhrajani
Division of Neurosurgery, University of Toronto, Ontario, Canada
J Neurosurg 109:2-7. 2008..The authors report treatment complications from the early experience of 2 Canadian GKS programs in Toronto and Sherbrooke... - Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticusClement Hamani
Division of Neurosurgery, Toronto Western Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada
Epilepsy Res 78:117-23. 2008..As the optimal stimulation settings remain elusive, we studied the effects of different stimulation parameters against pilocarpine induced seizures and status epilepticus (SE)... - Beta oscillatory activity in the subthalamic nucleus and its relation to dopaminergic response in Parkinson's diseaseMoran Weinberger
Department of Physiology, Med Sci Building 3302, 1 King's College Circle, University of Toronto, Toronto, Ontario M5S 1A8, Canada
J Neurophysiol 96:3248-56. 2006..The study also suggests that LFP beta oscillatory activity is generated largely within the dorsal portion of the STN and can produce synchronous oscillatory activity of the local neuronal population... - Advances in technology for intracranial stereotactic radiosurgeryArjun Sahgal
Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, The Princess Margaret Hospital, and the Joey Toby Tanenbaum family Gamma Knife Center, University of Toronto, Toronto, Ontario, Canada
Technol Cancer Res Treat 8:271-80. 2009..The focus of this review is to highlight recent advances and major innovations in SRS technologies relevant to clinical practice and developments allowing for non-invasive frame SRS... - Glioblastoma multiforme after stereotactic radiotherapy for acoustic neuroma: case report and review of the literatureAnandh Balasubramaniam
Arthur and Sonia Labatt Brain Tumor Center, Hospital for Sick Children, University of Toronto, 399 Bathurst St, 4W 446, Toronto, ON M5T 2S8, Canada
Neuro Oncol 9:447-53. 2007..However, the risk is not zero and requires discussion with the patient, with specific consideration in young patients and those with a cancer predisposition... - Bursting activity of neurons in the human anterior thalamic nucleusMojgan Hodaie
Division of Neurosurgery, University of Toronto, Toronto, ON M5S 1A8, Canada
Brain Res 1115:1-8. 2006..This study describes for the first time the properties of this nucleus in humans and may be important in furthering our knowledge of thalamic mechanisms of epileptogenesis... - Anesthesia for functional neurosurgery: review of complicationsLakshmi Venkatraghavan
Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
J Neurosurg Anesthesiol 18:64-7. 2006..Awareness and vigilance can improve the identification and early treatment of intraoperative complications such as seizures, loss of airway, and changes in the neurologic status...