Research Topics
Species | Jianxun HanSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibitionJianxun Han
Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2
Breast Cancer Res 11:R57. 2009....
Notch signaling as a therapeutic target for breast cancer treatment?Jianxun Han
Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, AB, Canada T6G 1Z2
Breast Cancer Res 13:210. 2011....
Quantitative analysis reveals asynchronous and more than DSB-associated histone H2AX phosphorylation after exposure to ionizing radiationJianxun Han
Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta T6G 1Z2, Canada
Radiat Res 165:283-92. 2006..In addition, we found that increased histone H2AX phosphorylation also occurred outside of DSB sites after exposure to ionizing radiation. The function of this DSB-unassociated phosphorylation is not known...
Characterization and comparison of protein complexes initiated by the intracellular domain of individual Notch paralogsJianxun Han
Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada T6G 1Z2
Biochem Biophys Res Commun 407:479-85. 2011..These results help to explain the dose-dependent and paralog-specific activities of NICD. These results are informative for the development of new reagents to block Notch signaling for therapeutic benefit...
