Amit X Garg

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Relationship between glomerular filtration rate and the prevalence of metabolic abnormalities: results from the Third National Health and Nutrition Examination Survey (NHANES III)
    Catherine M Clase
    Department of Medicine, McMaster University, Hamilton, Ont, Canada
    Nephron Clin Pract 105:c178-84. 2007
  2. ncbi Cardiovascular disease in kidney donors: matched cohort study
    Amit X Garg
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, ON, Canada
    BMJ 344:e1203. 2012
  3. ncbi The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
  4. ncbi Absence of renal sequelae after childhood Escherichia coli O157:H7 gastroenteritis
    A X Garg
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:807-12. 2006
  5. ncbi Identifying individuals with a reduced GFR using ambulatory laboratory database surveillance
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London Kidney Clinical Research Unit, Room A01, Westminster Tower, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada
    J Am Soc Nephrol 16:1433-9. 2005
  6. ncbi Long-term health sequelae following E. coli and campylobacter contamination of municipal water. Population sampling and assessing non-participation biases
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario
    Can J Public Health 96:125-30. 2005
  7. ncbi Risk of hypertension and reduced kidney function after acute gastroenteritis from bacteria-contaminated drinking water
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ont
    CMAJ 173:261-8. 2005
  8. ncbi Microalbuminuria three years after recovery from Escherichia coli O157 hemolytic uremic syndrome due to municipal water contamination
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, London, Canada
    Kidney Int 67:1476-82. 2005
  9. ncbi Lost in publication: Half of all renal practice evidence is published in non-renal journals
    A X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:1995-2005. 2006
  10. ncbi Proteinuria and reduced kidney function in living kidney donors: A systematic review, meta-analysis, and meta-regression
    A X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:1801-10. 2006

Detail Information

Publications125 found, 100 shown here

  1. ncbi Relationship between glomerular filtration rate and the prevalence of metabolic abnormalities: results from the Third National Health and Nutrition Examination Survey (NHANES III)
    Catherine M Clase
    Department of Medicine, McMaster University, Hamilton, Ont, Canada
    Nephron Clin Pract 105:c178-84. 2007
    ..73 m(2) undergo evaluation for anaemia and metabolic bone disease. We aim to report the prevalence of metabolic complications in adults with low GFR...
  2. ncbi Cardiovascular disease in kidney donors: matched cohort study
    Amit X Garg
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, ON, Canada
    BMJ 344:e1203. 2012
    ..To determine whether people who donate a kidney have an increased risk of cardiovascular disease...
  3. ncbi The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
    ..Previous studies on hospital-acquired AKI have important methodological limitations, especially their retrospective study designs and limited ability to control for potential confounding factors...
  4. ncbi Absence of renal sequelae after childhood Escherichia coli O157:H7 gastroenteritis
    A X Garg
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:807-12. 2006
    ..With no existing data to support screening after self-limited E. coli O157:H7 gastroenteritis, we recommend that only those children who develop recognized features of hemolytic uremic syndrome be followed for long-term renal health...
  5. ncbi Identifying individuals with a reduced GFR using ambulatory laboratory database surveillance
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London Kidney Clinical Research Unit, Room A01, Westminster Tower, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada
    J Am Soc Nephrol 16:1433-9. 2005
    ..Whether such identification leads to improved health outcomes warrants further study...
  6. ncbi Long-term health sequelae following E. coli and campylobacter contamination of municipal water. Population sampling and assessing non-participation biases
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario
    Can J Public Health 96:125-30. 2005
    ..We explored whether the association between the acute exposure and preliminary long-term health outcomes may have been biased through differences between early- and late-recruited study participants...
  7. ncbi Risk of hypertension and reduced kidney function after acute gastroenteritis from bacteria-contaminated drinking water
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ont
    CMAJ 173:261-8. 2005
    ..We studied the risk of hypertension and reduced kidney function after an outbreak of acute gastroenteritis due to contamination of a regional drinking water supply with Escherichia coli O157:H7 and Campylobacter species...
  8. ncbi Microalbuminuria three years after recovery from Escherichia coli O157 hemolytic uremic syndrome due to municipal water contamination
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, London, Canada
    Kidney Int 67:1476-82. 2005
    ..However, estimates of long-term risk are highly variable, with previous studies not using a healthy control group...
  9. ncbi Lost in publication: Half of all renal practice evidence is published in non-renal journals
    A X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:1995-2005. 2006
    ..However, relevant studies are also scattered across a large range of journals that may not be routinely scanned by busy physicians, and keeping up with this literature requires other continuing education strategies...
  10. ncbi Proteinuria and reduced kidney function in living kidney donors: A systematic review, meta-analysis, and meta-regression
    A X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 70:1801-10. 2006
    ..An initial decrement in GFR is not followed by accelerated losses over a subsequent 15 years. Future studies will provide better estimates, and identify those donors at least risk of long-term morbidity...
  11. ncbi Evaluating the impact of MEDLINE filters on evidence retrieval: study protocol
    Salimah Z Shariff
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Implement Sci 5:58. 2010
    ..The 'content' filters help identify articles in the discipline of renal medicine. We will now test the utility of these filters for physician MEDLINE searching...
  12. ncbi A gradient of acute gastroenteritis was characterized, to assess risk of long-term health sequelae after drinking bacterial-contaminated water
    Amit X Garg
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Clin Epidemiol 59:421-8. 2006
    ..We aimed to develop a method to grade the accuracy and severity of self-reported acute symptoms...
  13. ncbi Systematic review and meta-analysis: when one study is just not enough
    Amit X Garg
    Division of Nephrology and Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 3:253-60. 2008
  14. ncbi Albuminuria and estimated GFR 5 years after Escherichia coli O157 hemolytic uremic syndrome: an update
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Canada
    Am J Kidney Dis 51:435-44. 2008
    ..Estimates in the literature are highly variable, and previous studies did not use a healthy control group to establish outcomes attributable to HUS...
  15. ncbi Long-term renal prognosis of diarrhea-associated hemolytic uremic syndrome: a systematic review, meta-analysis, and meta-regression
    Amit X Garg
    Division of Adult and Pediatric Nephrology, University of Western Ontario, London, Canada
    JAMA 290:1360-70. 2003
    ..The long-term renal prognosis of patients with diarrhea-associated hemolytic uremic syndrome (HUS) remains controversial...
  16. ncbi Cardiovascular disease and hypertension risk in living kidney donors: an analysis of health administrative data in Ontario, Canada
    Amit X Garg
    1Division of Nephrology, University of Western Ontario, London, Canada
    Transplantation 86:399-406. 2008
    ..Risk estimates in the literature are variable, and most studies did not use a healthy control group to assess outcomes attributable to donation...
  17. ncbi Estimating the prevalence of renal insufficiency in seniors requiring long-term care
    Amit X Garg
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 65:649-53. 2004
    ..The objective of this study was to estimate the prevalence of low glomerular filtration rate (GFR) in a large sample of elderly adults living in long-term care facilities, and to compare two commonly used methods for estimating GFR...
  18. ncbi Filtering Medline for a clinical discipline: diagnostic test assessment framework
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, ON, Canada N6A 5C1
    BMJ 339:b3435. 2009
    ..To develop and test a Medline filter that allows clinicians to search for articles within a clinical discipline, rather than searching the entire Medline database...
  19. ncbi An outbreak of acute bacterial gastroenteritis is associated with an increased incidence of irritable bowel syndrome in children
    Marroon Thabane
    Division of Gastroenterology, Department of Medicine, and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 105:933-9. 2010
    ..We assessed this association among a cohort of children enrolled in the Walkerton Health Study (WHS)...
  20. ncbi Long term risk for hypertension, renal impairment, and cardiovascular disease after gastroenteritis from drinking water contaminated with Escherichia coli O157:H7: a prospective cohort study
    William F Clark
    Division of Nephrology, Department of Medicine, London Health Sciences Centre, London, ON, Canada
    BMJ 341:c6020. 2010
    ..To evaluate the risk for hypertension, renal impairment, and cardiovascular disease within eight years of gastroenteritis from drinking water contaminated with Escherichia coli O157:H7 and Campylobacter...
  21. ncbi Urine volume and change in estimated GFR in a community-based cohort study
    William F Clark
    Division of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada
    Clin J Am Soc Nephrol 6:2634-41. 2011
    ..The effect of increased fluid intake on kidney function is unclear. This study evaluates the relationship between urine volume and renal decline over 6 years in a large community-based cohort...
  22. ncbi Risk of pregnancy-related hypertension within 5 years of exposure to drinking water contaminated with Escherichia coli O157:H7
    Louise Moist
    Division of Nephrology, Department of Medicine, Victoria Hospital London Health Sciences Centre, 800 Commissioners Road East, London, Ontario, Canada
    J Clin Hypertens (Greenwich) 12:613-20. 2010
    ..05-5.4). A trend toward higher chronic hypertension and mean arterial pressure in early pregnancy was observed among women who experienced gastroenteritis after exposure to bacterially-contaminated drinking water...
  23. ncbi Cost-effectiveness analysis of a randomized trial comparing care models for chronic kidney disease
    Robert B Hopkins
    PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Clin J Am Soc Nephrol 6:1248-57. 2011
    ..This study examines the cost-effectiveness of a chronic disease management model for chronic kidney disease...
  24. ncbi Impact of PubMed search filters on the retrieval of evidence by physicians
    Salimah Z Shariff
    Division of Nephrology, University of Western Ontario, London, Ont
    CMAJ 184:E184-90. 2012
    ..We investigated whether the use of search filters in PubMed improves searching by physicians...
  25. ncbi Angiotensin inhibition in renovascular disease: a population-based cohort study
    Daniel G Hackam
    Division of Clinical Pharmacology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 156:549-55. 2008
    ....
  26. ncbi Albuminuria and renal insufficiency prevalence guides population screening: results from the NHANES III
    Amit X Garg
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 61:2165-75. 2002
    ..S. non-institutionalized population. Such knowledge guides the utility of population screening to prevent ESRD...
  27. ncbi Hemodialysis in a satellite unit: clinical performance target attainment and health-related quality of life
    Michael J Diamant
    Division of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada
    Clin J Am Soc Nephrol 6:1692-9. 2011
    ..The objective of this study is to compare clinical performance target attainment and health-related quality of life (HRQOL) in patients receiving HD in satellite versus in-center units...
  28. ncbi Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery
    John K Marshall
    Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, Canada
    Gut 59:605-11. 2010
    ....
  29. ncbi Elevated blood pressure in relation to overweight and obesity among children in a rural Canadian community
    Marina Salvadori
    Department of Pediatrics, Children s Hospital, London, Ontario, Canada
    Pediatrics 122:e821-7. 2008
    ..Rural populations in North America may be at increased risk for overweight. We evaluated whether overweight and obesity were associated with prehypertension and hypertension in a well-characterized population of children in rural Canada...
  30. ncbi Prevalence of uninvestigated dyspepsia 8 years after a large waterborne outbreak of bacterial dysentery: a cohort study
    Alexander C Ford
    Department of Medicine, Division of Gastroenterology, and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 138:1727-36; quiz e12. 2010
    ..We assessed prevalence of uninvestigated dyspepsia in a cohort of individuals, some of whom were exposed to bacterial dysentery in May 2000, as well as risk factors for dyspepsia in exposed individuals...
  31. ncbi Beta-blockers, trimethoprim-sulfamethoxazole, and the risk of hyperkalemia requiring hospitalization in the elderly: a nested case-control study
    Matthew A Weir
    University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 5:1544-51. 2010
    ..The simultaneous use of beta adrenergic receptor blockers (beta-blockers) and trimethoprim-sulfamethoxazole (TMP-SMX) may confer a high risk of hyperkalemia...
  32. ncbi Searching for medical information online: a survey of Canadian nephrologists
    Salimah Z Shariff
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
    J Nephrol 24:723-32. 2011
    ..Physicians often search for information to improve patient care. We evaluated how nephrologists use online information sources for this purpose...
  33. ncbi Discovering misattributed paternity in living kidney donation: prevalence, preference, and practice
    Ann Young
    Division of Nephrology, University of Western Ontario, London, ON, Canada
    Transplantation 87:1429-35. 2009
    ..Opinions on how to deal with this sensitive information are variable. Discussion among transplant professionals will facilitate best practices and policies. Strategies adopted by some centers can be considered...
  34. ncbi Dipstick proteinuria as a screening strategy to identify rapid renal decline
    William F Clark
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Am Soc Nephrol 22:1729-36. 2011
    ..In summary, inexpensive screening with urine dipstick should allow primary care physicians to follow fewer patients with serial eGFR assessment but still identify those with rapid decline of kidney function...
  35. ncbi Living kidney donors' experiences with the health care system
    Judith Belle Brown
    Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, Suite 245, 100 Collip Circle, London, ON, Canada N6G 4X8
    Soc Work Health Care 46:53-68. 2008
    ..The findings of this study provide suggestions for the role of social work and improvement in the health care system to better address the needs of living kidney donors...
  36. ncbi Impaired renal function modifies the risk of severe hypoglycaemia among users of insulin but not glyburide: a population-based nested case-control study
    Matthew A Weir
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Canada
    Nephrol Dial Transplant 26:1888-94. 2011
    ..Little evidence justifies the avoidance of glyburide in patients with impaired renal function. We aimed to determine if renal function modifies the risk of hypoglycaemia among patients using glyburide...
  37. ncbi Meta-analysis: risk for hypertension in living kidney donors
    Neil Boudville
    University of Western Ontario, London, Ontario, Canada
    Ann Intern Med 145:185-96. 2006
    ..Future controlled, prospective studies with long periods of follow-up will better delineate safety and identify donors at lowest risk for long-term morbidity...
  38. ncbi Optimal search filters for renal information in EMBASE
    Arthur V Iansavichus
    Division of Nephrology, University of Western Ontario, London, Canada
    Am J Kidney Dis 56:14-22. 2010
    ..EMBASE is a popular database used to retrieve biomedical information. Our objective was to develop and test search filters to help clinicians and researchers efficiently retrieve articles with renal information in EMBASE...
  39. ncbi Impact of estimated GFR reporting on patients, clinicians, and health-care systems: a systematic review
    Yoan K Kagoma
    Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
    Am J Kidney Dis 57:592-601. 2011
    ..A summary of the impact of eGFR reporting in health care systems around the world for which it has been adopted is lacking...
  40. ncbi Diabetes during diarrhea-associated hemolytic uremic syndrome: a systematic review and meta-analysis
    Rita S Suri
    Kidney Clinical Research Unit, Division of Nephrology, London Health Sciences Center, University of Western Ontario, Room ELL 111 Victoria Hospital, 800 Commissioners Rd East, London, Ontario, Canada N6A 4G5
    Diabetes Care 28:2556-62. 2005
    ..To quantify the incidence of diabetes during the acute phase of diarrhea-associated hemolytic uremic syndrome (D + HUS) and to identify features associated with its development...
  41. ncbi New fibrate use and acute renal outcomes in elderly adults: a population-based study
    Ying Y Zhao
    The Yale University School of Medicine, New Haven, Connecticut University of Western Ontario, London, Ontario, Canada Institute for Clinical Evaluative Sciences, University of Toronto, and Keenan Research Centre in the Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada and McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 156:560-9. 2012
    ..The mechanism and clinical significance of the increase in serum creatinine level with fibrates is unclear. Primary Funding Source: Ontario Ministry of Health and Long-Term Care Drug Innovation Fund...
  42. ncbi When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase
    Arsh K Jain
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Kidney Int 76:318-23. 2009
    ..However, it remains to be seen whether the routine reporting of eGFR results in improved treatment and outcomes for those with chronic kidney disease...
  43. ncbi Global trends in the rates of living kidney donation
    Lucy Diane Horvat
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 75:1088-98. 2009
    ..Our study shows that rates of living donor kidney transplant have steadily risen in most regions of the world, increasing its global significance as a treatment option for kidney failure...
  44. ncbi Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis
    Alexandra Chloe Villani
    Division of Gastroenterology, Department of Medicine, McGill University, Montreal, Quebec, Canada
    Gastroenterology 138:1502-13. 2010
    ..2% of these developed IBS. We used this cohort to study genetic susceptibility to post-infectious (PI)-IBS...
  45. ncbi Optimal method of coronary revascularization in patients receiving dialysis: systematic review
    Immaculate F Nevis
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 4:369-78. 2009
    ..Patients receiving dialysis have a high burden of cardiovascular disease. Some receive coronary artery revascularization but the optimal method is controversial...
  46. ncbi Excessive fluid intake as a novel cause of proteinuria
    William F Clark
    Department of Medicine Nephrology, London Health Sciences Centre, University of Western Ontario, London, Ont
    CMAJ 178:173-5. 2008
    ..We do not know at this time whether the proteinuria associated with excessive fluid intake in these otherwise healthy people will affect their kidney function in the long term...
  47. ncbi Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: nested case-control study
    Tony Antoniou
    University of Toronto, Toronto, ON, Canada
    BMJ 343:d5228. 2011
    ..To characterise the risk of admission to hospital for hyperkalaemia in elderly patients treated with trimethoprim-sulfamethoxazole in combination with spironolactone...
  48. ncbi Current Canadian initiatives to reimburse live organ donors for their non-medical expenses
    Sorina Vlaicu
    Department of Political Science, University of Western Ontario, London, ON, Canada
    Can J Public Health 98:481-3. 2007
    ..Developing future reimbursement policies will remove a disincentive faced by some potential donors, and may increase rates of transplantation in Canada...
  49. ncbi Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery
    John K Marshall
    Department of Medicine, Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 131:445-50; quiz 660. 2006
    ..To better define its incidence and epidemiology, a large cohort study was initiated after the contamination of a municipal water supply led to a large outbreak of acute Escherichia coli 0157:H7 and Campylobacter jejuni gastroenteritis...
  50. ncbi Diagnostic accuracy of cystatin C-based eGFR equations at different GFR levels in children
    Ajay P Sharma
    Department of Pediatrics, Division of Pediatric Nephrology, Children s Hospital, London Health Sciences Centre, University of Western Ontario, London, Ontario, N6A 5W9 Canada
    Clin J Am Soc Nephrol 6:1599-608. 2011
    ..The diagnostic accuracy of cystatin C estimated GFR (eGFR) by various cystatin C equations have varied in different studies. We hypothesized that the GFR level of enrolled patients affects the diagnostic accuracy of a cystatin C equation...
  51. ncbi Big mother or small baby: which predicts hypertension?
    Guido Filler
    Department of Pediatrics, Division of Pediatric Nephrology, Children s Hospital, London, Ontario, Canada
    J Clin Hypertens (Greenwich) 13:35-41. 2011
    ..This study suggests that a high BMI, a big mom, and a high birth weight are more important risk factors for hypertension during childhood than low birth weight or gestational age...
  52. ncbi Impact of contraindications, barriers to self-care and support on incident peritoneal dialysis utilization
    Matthew J Oliver
    Division of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada
    Nephrol Dial Transplant 25:2737-44. 2010
    ..The objectives of this study were to determine the impact that contraindications and barriers to self-care have on incident PD use, and to determine whether family support increased PD utilization when home care support is available...
  53. ncbi Beta-blockers and cardiovascular outcomes in dialysis patients: a cohort study in Ontario, Canada
    Abhijat Kitchlu
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Nephrol Dial Transplant 27:1591-8. 2012
    ..Beta-blockers may be cardioprotective in patients receiving chronic dialysis. We examined cardiovascular outcomes among incident dialysis patients receiving beta-blocker therapy...
  54. ncbi Computerized clinical decision support systems for chronic disease management: a decision-maker-researcher partnership systematic review
    Pavel S Roshanov
    Health Research Methodology Program, McMaster University, 1280 Main Street West, Hamilton, ON, Canada
    Implement Sci 6:92. 2011
    ....
  55. ncbi Choosing peritoneal dialysis reduces the risk of invasive access interventions
    Matthew J Oliver
    Division of Nephrology, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, Canada
    Nephrol Dial Transplant 27:810-6. 2012
    ..The objective of this study was to compare the risk of access interventions between the two modalities...
  56. ncbi Informing the debate: rates of kidney transplantation in nations with presumed consent
    Lucy D Horvat
    University of Western Ontario, London University of Waterloo, Waterloo and University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 153:641-9. 2010
    ..The organ shortage has caused policymakers in many nations to debate the merits of adopting presumed consent legislation as a way to increase donor organ donation from deceased donors...
  57. ncbi Classifying kidney problems: can we avoid framing risks as diseases?
    Catherine M Clase
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    BMJ 329:912-5. 2004
  58. ncbi Results of a randomized controlled trial on statin use in dialysis patients had no influence on statin prescription
    Ngan N Lam
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Canada
    Kidney Int 76:1172-9. 2009
    ..The use of a common cardiovascular medication in this patient population appears to be influenced by other factors...
  59. ncbi Intensive hemodialysis associates with improved survival compared with conventional hemodialysis
    Gihad E Nesrallah
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    J Am Soc Nephrol 23:696-705. 2012
    ..In conclusion, there is a strong association between intensive home hemodialysis and improved survival, but whether this relationship is causal remains unknown...
  60. ncbi Do biochemical measures change in living kidney donors? A systematic review
    Ann Young
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Nephron Clin Pract 107:c82-9. 2007
    ..We reviewed studies which followed 5 or more healthy donors, where changes in biochemical measures or anemia were assessed at least 4 months after nephrectomy...
  61. ncbi Need for quality improvement in renal systematic reviews
    Marko Mrkobrada
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 3:1102-14. 2008
    ..This study assessed the methodologic quality of all systematic reviews relevant to the practice of nephrology published in 2005...
  62. ncbi Use of clinical decision support systems for kidney-related drug prescribing: a systematic review
    Davy Tawadrous
    Schulich School of Medicine, University of Western Ontario, London, Ontario, Canada Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Am J Kidney Dis 58:903-14. 2011
    ..Clinical decision support systems (CDSSs) have the potential to improve kidney-related drug prescribing by supporting the appropriate initiation, modification, monitoring, or discontinuation of drug therapy...
  63. ncbi Helping patients follow prescribed treatment: clinical applications
    R Brian Haynes
    Department of Clinical Epidemiology and Biostatistics, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada
    JAMA 288:2880-3. 2002
    ..Successful interventions for long-term regimens are all labor-intensive but ultimately can be cost-effective...
  64. ncbi The International Quotidian Dialysis Registry: annual report 2006
    Gihad E Nesrallah
    Humber River Regional Hospital, Toronto, ON, Canada
    Hemodial Int 10:219-24. 2006
    ..This paper constitutes the second annual update on patient and center recruitment, patient and treatment characteristics, and future directions for the registry...
  65. ncbi Statins and renovascular disease in the elderly: a population-based cohort study
    Daniel G Hackam
    Stroke Prevention and Atherosclerosis Research Centre, University of Western Ontario, Siebens Drake Research Institute, London, Ontario, Canada
    Eur Heart J 32:598-610. 2011
    ..More than 90% of cases of renovascular disease (RVD) are caused by atherosclerosis; thus patients with this condition are at high risk for vascular events. We examined the association of statins with prognosis in patients with RVD...
  66. ncbi Evaluation of GFR estimating equations in the general community: implications for screening
    William F Clark
    University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada
    Clin J Am Soc Nephrol 1:787-95. 2006
    ..The calibrated Rule equation seems to perform better than CG and MDRD (CKD 3 versus 11.3 to 12%) but lacks validation against gold standards for community-based screening...
  67. ncbi Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery
    Michael Zappitelli
    Division of Nephrology, Department of Pediatrics, Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Kidney Int 80:655-62. 2011
    ..Thus, postoperative serum CysC is useful to risk-stratify patients for AKI treatment trials. More research, however, is needed to understand the relation between preoperative renal function and the risk of AKI...
  68. ncbi Diagnostic test systematic reviews: bibliographic search filters ("Clinical Queries") for diagnostic accuracy studies perform well
    Monika Kastner
    Department of Clinical Epidemiology and Biostatistics, Health Information Research Unit, McMaster University, Hamilton, Ontario, Canada
    J Clin Epidemiol 62:974-81. 2009
    ..Systematic reviews of health care topics are valuable summaries of all pertinent studies on focused questions. However, finding all relevant primary studies for systematic reviews remains challenging...
  69. ncbi Plasma exchange when myeloma presents as acute renal failure: a randomized, controlled trial
    William F Clark
    University of Western Ontario, London, Ontario, Canada
    Ann Intern Med 143:777-84. 2005
    ..29 mL.s(-2).m(-2) (<30 mL/min per 1.73 m2) at 6 months...
  70. ncbi A method for defining a journal subset for a clinical discipline using the bibliographies of systematic reviews
    Nancy L Wilczynski
    Health Information Research Unit, McMaster University, Hamilton, Ontario, Canada
    Stud Health Technol Inform 129:721-4. 2007
    ..If "virtual journal subsets" that are likely to include all relevant articles can be defined for clinical discipline areas or disease content areas this will likely improve search precision...
  71. ncbi An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods
    P J Devereaux
    Department of Medicine, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    J Clin Epidemiol 57:1232-6. 2004
    ..We undertook an observational study to determine whether concealment of randomization or blinding was used in RCTs that failed to report these bias-reducing strategies...
  72. ncbi Statin use associates with a lower incidence of acute kidney injury after major elective surgery
    Amber O Molnar
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Canada
    J Am Soc Nephrol 22:939-46. 2011
    ..79; 95% CI, 0.74 to 0.85). Propensity score matching produced similar results. These data suggest that statins may protect against renal complications after major elective surgery and reduce perioperative mortality...
  73. ncbi Daily hemodialysis: a systematic review
    Rita S Suri
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 1:33-42. 2006
    ..Randomized trials with adequate statistical power are required to establish the efficacy and the safety of DHD...
  74. ncbi Minutes to recovery after a hemodialysis session: a simple health-related quality of life question that is reliable, valid, and sensitive to change
    Robert M Lindsay
    Division of Nephrology and Optimal Dialysis Research Unit, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 1:952-9. 2006
    ..As such, it should be considered as a standard question in HD-related studies in which a health-related quality-of-life outcome is examined...
  75. ncbi Prevalence of low glomerular filtration rate in nondiabetic Americans: Third National Health and Nutrition Examination Survey (NHANES III)
    Catherine M Clase
    Department of Medicine, McMaster University, Hamilton, Ontario
    J Am Soc Nephrol 13:1338-49. 2002
    ..The prognosis (in terms of risk for progression and end-stage renal disease) of low clearance in unreferred populations may differ from that in referred populations and requires further study...
  76. ncbi Effect of antitubercular medications on blood pressure control in chronic kidney disease patients with tuberculosis: a prospective cohort study
    Ajay P Sharma
    Department of Pediatrics, University of Western Ontario, London, Ontario, Canada
    J Nephrol 19:771-7. 2006
    ..This interaction could be unpredictable in presence of renal failure due to increased half-lives of most commonly used antihypertensive medications...
  77. ncbi Randomized trials of frequent hemodialysis--infinite possibilities
    Rita S Suri
    Division of Nephrology, London Health Sciences Center, University of Western Ontario, London, Ont, Canada
    Blood Purif 24:123-7. 2006
    ..The 'ideal' trial in terms of methods must be balanced against the feasibility of implementation and budgetary constraints. Here, we explore some of these issues...
  78. ncbi A validation study of the Canadian Organ Replacement Register
    Louise M Moist
    Division of Nephrology, London Health Sciences Centre, and the University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 6:813-8. 2011
    ..The objectives of this study were to assess the quality of data collected in the Canadian Organ Replacement Register (CORR) compared with the patient's medical charts...
  79. ncbi Frequent Hemodialysis Network (FHN) randomized trials: study design
    R S Suri
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 71:349-59. 2007
    ....
  80. ncbi Insurability of living organ donors: a systematic review
    R C Yang
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Am J Transplant 7:1542-51. 2007
    ..If better understood, this potential barrier to donation could be corrected through fair health and underwriting policies...
  81. ncbi Transplant professionals vary in the long-term medical risks they communicate to potential living kidney donors: an international survey
    A A Housawi
    Division of Nephrology, University of Western Ontario, London, Canada
    Nephrol Dial Transplant 22:3040-5. 2007
    ..Discussing long-term medical risks with potential living donors is a vital aspect of informed consent. We considered whether there are global practice variations in the information communicated to potential living kidney donors...
  82. ncbi Accepting kidneys from older living donors: impact on transplant recipient outcomes
    A Young
    Division of Nephrology, University of Western Ontario, Canada
    Am J Transplant 11:743-50. 2011
    ..29 (0.80-2.08)]. In light of an observed trend towards potential differences beyond 4 years, uncertainty remains, and extended follow-up of this and other cohorts is warranted...
  83. ncbi Imputing variance estimates do not alter the conclusions of a meta-analysis with continuous outcomes: a case study of changes in renal function after living kidney donation
    H Thiessen Philbrook
    Division of Nephrology, University of Western Ontario, London, Canada
    J Clin Epidemiol 60:228-40. 2007
    ..To assess how different imputation methods used to account for missing variance data in primary studies influence tests of heterogeneity and pooled results from a meta-analysis with continuous outcomes...
  84. ncbi Recipient outcomes for expanded criteria living kidney donors: the disconnect between current evidence and practice
    Y Iordanous
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Am J Transplant 9:1558-73. 2009
    ..This disconnect between donor selection and a lack of knowledge of recipient outcomes should give transplant decision-makers pause and sets an agenda for future research...
  85. ncbi Plasma exchange for myeloma kidney: cast(s) away?
    W F Clark
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Kidney Int 73:1211-3. 2008
    ..The analysis supports restitution of a better RCT of plasma exchange for myeloma kidney rather than off-label use...
  86. ncbi Carotid endarterectomy benefits patients with CKD and symptomatic high-grade stenosis
    Anna Mathew
    University of Western Ontario, London, Ontario, Canada
    J Am Soc Nephrol 21:145-52. 2010
    ..In conclusion, patients with stage 3 CKD and symptomatic high-grade carotid stenosis gain a large benefit in stroke risk reduction after endarterectomy...
  87. ncbi Psychosocial health of living kidney donors: a systematic review
    K K Clemens
    Division of Nephrology, University of Western Ontario, London, Canada
    Am J Transplant 6:2965-77. 2006
    ..A small proportion of donors had adverse psychosocial outcomes. Most kidney donors experience no change or an improvement in their psychosocial health after donation. Harms may be minimized through careful selection and follow-up...
  88. ncbi Life insurance for living kidney donors: a Canadian undercover investigation
    R C Yang
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Transplant 9:1585-90. 2009
    ..We found no evidence that kidney donors were disadvantaged in the first step of applying for life insurance. The effect donation has on subsequent phases of insurance underwriting remains to be studied...
  89. ncbi Moderate renal insufficiency and the risk of cardiovascular mortality: results from the NHANES I
    Amit X Garg
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 61:1486-94. 2002
    ..S. general non-institutionalized population...
  90. ncbi Chronic kidney disease and mortality risk: a systematic review
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Alberta T6B 2B7, Canada
    J Am Soc Nephrol 17:2034-47. 2006
    ..0 in 71% of cohorts. This review supports current guidelines that identify individuals with CKD as being at high risk for cardiovascular mortality. Determining which interventions best offset this risk remains a health priority...
  91. ncbi The direct and indirect economic costs incurred by living kidney donors-a systematic review
    Katherine S Clarke
    Division of Nephrology, University of Western Ontario, Canada
    Nephrol Dial Transplant 21:1952-60. 2006
    ..To guide informed consent and fair reimbursement policies, further data on all relevant costs, preferably from a detailed prospective multi-centre cohort study, are required...
  92. ncbi Living organ donors face financial barriers: a national reimbursement policy is needed
    Scott Klarenbach
    Department of Medicine, Division of Nephrology, University of Alberta and the Institute of Health Economics, Edmonton, Alta
    CMAJ 174:797-8. 2006
  93. ncbi Attitudes to sharing personal health information in living kidney donation
    Patricia Hizo-Abes
    London Kidney Clinical Research Unit, Room ELL 101, Westminster, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada
    Clin J Am Soc Nephrol 5:717-22. 2010
    ..In incompatible kidney exchange, personal health information from multiple living donors and recipients may affect decision making and outcomes...
  94. ncbi Interventions to enhance patient adherence to medication prescriptions: scientific review
    Heather P McDonald
    Health Research Methodology Program, McMaster University School of Graduate Studies, Hamilton, Ontario, Canada
    JAMA 288:2868-79. 2002
    ..The full benefits of medications cannot be realized at currently achievable levels of adherence; therefore, more studies of innovative approaches to assist patients to follow prescriptions for medications are needed...
  95. ncbi Age affects outcomes in chronic kidney disease
    ANN M O'HARE
    Department of Medicine, University of Washington, VA Puget Sound Healthcare System, Division of Nephrology, Building 100 Room 5B113, 1660 S Columbian Way, Seattle, WA 98108, USA
    J Am Soc Nephrol 18:2758-65. 2007
    ..73 m(2). In conclusion, age is a major effect modifier among patients with an eGFR of <60 ml/min per 1.73 m(2), challenging us to move beyond a uniform stage-based approach to managing CKD...
  96. ncbi Reimbursing live organ donors for incurred non-medical expenses: a global perspective on policies and programs
    M Sickand
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Am J Transplant 9:2825-36. 2009
    ..Many nations have programs that help living donors with their financial costs. These programs differ in operation and scope. Donors in other regions of the world are without support...
  97. ncbi Causes of reversible nephrogenic diabetes insipidus: a systematic review
    Camelia G Garofeanu
    Division of Nephrology, Walkerton Health Study, London Health Science Centre, Westminster Campus, Canada
    Am J Kidney Dis 45:626-37. 2005
    ..CONCLUSION: Most risk factors for reversible NDI were medications, and their identification and removal resulted in resolution of the condition. Long-term treatment with lithium seemed to result in irreversible NDI...
  98. ncbi Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis
    Normand L Proulx
    Department of Medicine, University of Western Ontario, London, Ontario N6A 4G5, Canada
    Nephrol Dial Transplant 20:1617-22. 2005
    ..The objective of this study was to review the accuracy of measured creatinine clearance (MCrCl) from timed urine collections for estimating true GFR...
  99. ncbi Campylobacter reactive arthritis: a systematic review
    Janet E Pope
    Division of Rheumatology, Department of Medicine, The University of Western Ontario, Ontario, Canada
    Semin Arthritis Rheum 37:48-55. 2007
    ..To review the literature on the epidemiology of Campylobacter-associated reactive arthritis (ReA)...
  100. ncbi Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis
    P J Devereaux
    Depatment of Medicine, McMaster University, Faculty of Health Sciences, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 288:2449-57. 2002
    ..There has been extensive debate about whether the profit status of these facilities influences patient mortality...
  101. ncbi Health outcomes for living kidney donors with isolated medical abnormalities: a systematic review
    A Young
    Division of Nephrology, Univerity of Western Ontario, London, ON, Canada
    Am J Transplant 8:1878-90. 2008
    ..As transplant centers continue to cautiously screen and counsel potential IMA donors, rigorously conducted, longer term prospective cohort studies are needed...