Research Topics
| Michael T ClandininSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
The effect of treating infected skin grafts with Acticoat on immune cellsVera C Mazurak
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alta, Canada T6G 2P5
Burns 33:52-8. 2007....- Cholesterolaemic effect of palmitic acid in relation to other dietary fatty acidsMargaret A French
Nutrition and Metabolism Research Group, Departments of Agricultural, Food and Nutritional Science and Medicine, University of Alberta, Edmonton, Canada
Asia Pac J Clin Nutr 11:S401-7. 2002..5% of energy. When the diet contained trans fatty acids plasma total and low-density lipoprotein-cholesterol increased and cholesterol synthesis increased with a decrease in high-density lipoprotein-cholesterol... - The role of dietary long-chain n-3 fatty acids in anti-cancer immune defense and R3230AC mammary tumor growth in rats: influence of diet fat compositionLindsay E Robinson
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
Breast Cancer Res Treat 73:145-60. 2002..These findings warrant further consideration when designing dietary recommendations... - Effect of providing a formula supplemented with long-chain polyunsaturated fatty acids on immunity in full-term neonatesCatherine J Field
Nutrition and Metabolism Research Group, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
Br J Nutr 99:91-9. 2008..Since many diseases have a strong immunological component, these immune changes may be of physiological importance to the developing infant... - Exchanging partially hydrogenated fat for palmitic acid in the diet increases LDL-cholesterol and endogenous cholesterol synthesis in normocholesterolemic womenKalyana Sundram
Malaysian Palm Oil Board Kuala Lumpur, Malaysia
Eur J Nutr 42:188-94. 2003..Consumption of hydrogenated fats containing trans fatty acids in comparison to a mixtur e of palmitic and oleic acids increase plasma cholesterol levels apparently by increasing endogenous synthesis of cholesterol... - Alterations in lymphocyte function and relation to phospholipid composition after burn injury in humansVera C Pratt
Department of Agricultural, Food, and Nutritional Science, University of Alberta, Ed-monton, Alberta, Canada
Crit Care Med 30:1753-61. 2002..This study suggests that there is release or impaired synthesis of 20:4n-6 early after burn injury that may be related to functional changes in immune cells... - Dietary lipids alter the effect of steroids on transport of glucose after intestinal resection: Part II. Signalling of the responseAducio L Thiesen
Nutrition and Metabolism Research Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
J Pediatr Surg 38:575-8. 2003..Ornithine decarboxylase (ODC) expression was reduced in the jejunum. CONCLUSIONS: c-jun, ODC, and proglucagon may be involved in the adaptive response that occurs with steroids and variations in dietary lipids after intestinal resection... - Postnatal dietary supplementation with either gangliosides or choline: effects on spatial short-term memory in artificially-reared ratsPatricia E Wainwright
Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ont, Canada
Nutr Neurosci 10:67-77. 2007..Thus, all rats were equally proficient at using spatial short-term memory, regardless of the choline or ganglioside content of the preweaning diet... - Influence of dietary saturated fatty acids on the regulation of plasma cholesterol concentrationMichaelann S Wilke
Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Alberta, Canada T6G 2H1
Lipids 40:1207-13. 2005..Some of the relevant research regarding dietary fat and plasma cholesterol levels is reviewed... - 20:5n-3 but not 22:6n-3 is a preferred substrate for synthesis of n-3 very-long- chain fatty acids (C24-C36) in retinaMiyoung Suh
Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
Curr Eye Res 30:959-68. 2005..These observations suggest that 22:6n-3 is incorporated directly into retinal phospholipids without further metabolism, whereas 20:5n-3 and 22:5n-3 are metabolically active precursors for synthesis of VLCFAs... - Dietary gangliosides increase the content and molecular percentage of ether phospholipids containing 20:4n-6 and 22:6n-3 in weanling rat intestineEek J Park
Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Canada T6G 2P5
J Nutr Biochem 17:337-44. 2006..The present data demonstrate that dietary GG increases the content and composition of EPL containing PUFA in the weanling rat intestine... - Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retinaEek Joong Park
Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Canada
Invest Ophthalmol Vis Sci 46:2571-5. 2005..Feeding animals dietary LCPs also affected ganglioside metabolism in the developing retina, suggesting a new mechanism by which these dietary lipids may promote maturation of photoreceptor cells... - Dietary ganglioside decreases cholesterol content, caveolin expression and inflammatory mediators in rat intestinal microdomainsEek Joong Park
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
Glycobiology 15:935-42. 2005..Dietary gangliosides decrease the cholesterol/ganglioside ratio, caveolin, PAF and DG content in microdomains thus exerting a potential anti-inflammatory effect during gut development... - Dietary lipids alter the effect of steroids on the transport of glucose after intestinal resection: Part I. Phenotypic changes and expression of transportersAducio L Thiesen
Nutrition and Metabolism Research Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Canada
J Pediatr Surg 38:150-60. 2003..Thus, the desired intestinal adaptive response after intestinal resection may be enhanced further by the administration of the locally acting steroid budesonide and by feeding a saturated compared with a polyunsaturated fatty acid diet... - Diet-induced changes in membrane gangliosides in rat intestinal mucosa, plasma and brainEek Joong Park
Nutrition and Metabolism Research Group, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
J Pediatr Gastroenterol Nutr 40:487-95. 2005.... - Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegansGiovanni M Lesa
Molecular Neuropathobiology Laboratory, Cancer Research UK, London Research Institute, Lincoln s Inn Fields Laboratories, 44 Lincoln s Inn Fields, London WC2A 3PX, UK
J Cell Sci 116:4965-75. 2003..These data indicate that LC-PUFAs are essential for efficient neurotransmission in C. elegans and may account for the clinical conditions associated with mis-regulation of LC-PUFAs in humans... - Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acidM Thomas Clandinin
University of Alberta, Edmonton, Alberta, Canada
J Pediatr 146:461-8. 2005..CONCLUSIONS: Feeding formulas with DHA and ARA from algal and fungal oils resulted in enhanced growth. Both supplemented formulas provided better developmental outcomes than unsupplemented formulas...