Jagdish W Butany

..The microorganism was Streptococcus viridans and the vegetations were surprisingly large and led to prosthesis obstruction...

..The goal of this work was to determine wall shear stress (WSS) patterns in the human abdominal aorta and to compare these patterns to measurements of intimal thickness (IT) from autopsy samples...

..Hypersensitivity myocarditis is also discussed...

..Consequently, cardiac neoplasms, especially metastatic ones, are often not discovered until autopsy...

..Patients with sarcomas live for a mean of 3 months to 1 year, and those with lymphomas live up to 5 years if treated, but usually die within 1 month if untreated...

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..With good patient compliance, this mechanical heart valve prosthesis is an example of good prosthetic valve durability...

..However, the majority of CP cases are idiopathic. This report presents three cases of postoperative, tuberculous and idiopathic CP, highlighting the clinical and pathological changes seen in CP, and a review of the literature...

..Eosinophilic myocarditis has been reported with an incidence of 2.4% to 7.2% in explanted hearts and may be related to multidrug therapy...

..0 cm in diameter. While myxomas commonly arise from the interatrial septum, we present the rare example of a large papillary fibroelastoma arising from the left side of the interatrial septum...

..The summaries accompanying each stent include concise physical descriptions and documented complications, intended to serve as a guide for the investigating pathologist...

..Inflammatory cells were composed mainly of lymphocytes and macrophages, and were located primarily near areas of neovascularization. There was no significant difference in the pathological findings between men and women...

..Stentless porcine valves have many documented advantages over stented valves. Since its introduction in 1991, the Toronto stentless porcine valve (T-SPV) has shown excellent hemodynamic performance...

..The incidence, characteristics, and the therapeutic options for such membranes in adults have not been well documented. This report documents the clinical and pathological features of DSM in adults...

..This study presents the pathological findings of the ascending aorta in patients with UAV...

..Clinically, IMT mimics malignancy, making a definitive diagnosis difficult, prior to histopathological examination...

..This valve reportedly has excellent clinical and hemodynamic results, but little has been reported about its long-term pathology...

..Although second-generation bioprosthetic valves have improved functionality over their first-generation counterparts, they still often fail due to primary tissue degeneration...

..Pathological examination confirmed tissue destruction, friable thrombotic vegetations, and microorganisms in the leaflet tissue...

..We present the first series of human morphological data on the failure of these valves...

..The longevity of this pericardial valve may have been related to excessive pannus growth, which most likely protected the valve from earlier failure...

..Successful diagnosis of this disease is difficult due to its nonspecific symptoms which mimic those of idiopathic dilated cardiomyopathy (IDCM)...

..This can manifest as pigmentation in the skin and other tissues, including heart valves. Accumulation of this pigment can lead to an inflammatory reaction and to progressive valve dysfunction...

..We report the first instance (in the literature) of rupture of a synthetic (PTFE) chordae tendinae. The synthetic suture (PTFE) was associated with calcification...

..This review highlights some of the growing body of evidence implicating endothelial dysfunction as an important mediator of diverse diseases...

..Two cases of failure of this prosthesis, with a clinical diagnosis of infective endocarditis, are presented...

..This article reviews the modes of failure of bioprosthetic heart valves...

..Deficiency or degeneration of one or more of these structures may result in dysfunction of the valvular apparatus leading to mitral valve prolapse during systole...

..Of these, cardiac angiosarcomas are uncommon and, until recently, almost invariably diagnosed at the time of autopsy, primarily because the symptoms are initially nonspecific and do not become manifest until the tumour is advanced...

..This accuracy of identification as well as tracking of abnormalities noted will, we hope, permit the identification of new failure modes and the recording of causes of failure of new (or even modified) prosthetic heart valves...

..Further, contrary to previous thinking, the frequency of aortic valvular dysfunction does not appear to be related to valve morphology...

..Transcatheter aortic valve implantation (TCAVI) is an emerging alternative therapy to open-heart surgery in high-risk patients with symptomatic aortic stenosis...

..Diagnosis, treatment and preventive measures, if taken in a timely manner, can help reduce their impact and further enhance the quality of life of patients with prosthetic heart valves...

..The durability of this PH was likely due to a combination of low pressure on the right side of the heart and the patient's age at surgery...

..This study evaluates the clinical outcomes and the risk of dilation and rupture of porcine aortic roots after implantation...

..There was a perforation in the patch with fibrosis, thickening due to pannus, and calcification of the pericardial tissue and the leaflet tissue, leading to stiffening of the tissue...

..Herein, we report the morphological findings in inflow and outflow explanted bioprostheses from seven such devices...

..A review of the literature suggests that this case is the first reported experience with the three pathologies occurring in combination...

..The valve itself was intact and fully functional. We believe the longevity of this valve was due to the decreased flow velocities and the lower pressure in the mitral valve position...

..The role of the inflammatory cell reaction in the bioprosthetic valve is discussed...

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..We report a patient who had an acute cerebral hemorrhage, developed a progressive mass lesion obstructing his mechanical mitral valve, and discuss contemporary diagnostic and management strategies...

..The patient did well for 17 years, but needed further reconstruction when the pulmonary valve started getting stenosed and RV pressures went up significantly. The pulmonary valve showed fibroses, thickening, and focal calcification...

..To aid in the differential diagnosis and management of SARS, radiologists must be familiar with the typical clinical and histopathologic findings, as well as the radiologic features of the disease...

..In the homograft, maturation of pannus had produced shortening of the 3 cusps with resultant incompetence...

..Diagnosis, treatment, prognosis and literature are reviewed, and consideration of this tumour in the differential diagnosis of other pulmonary diseases is emphasized...

..Primary tumors of the pericardium are extremely rare and occur in a broad age range. This review describes several of the more common lesions: germ cell tumors, solitary fibroma, pericardial mesothelioma, and metastatic disease...

..This process of vascular matrix remodeling in patients with bicuspid aortic valves offers novel therapeutic targets to prevent the aortic degeneration and dilatation characteristic of this disease...

..Cases of SARS may be complicated by coexistent infections and therapy-related lung injury...

..Percutaneous mitral repair with the MitraClip device ("clip") is currently being evaluated in a Phase II clinical trial (EVEREST II). This device was evaluated in an animal model prior to use in humans...

..We describe a combined thyroidectomy, aortic valve replacement, and coronary artery bypass graft surgery on a patient with an asymptomatic retrosternal thyroid mass...

..The tumors are, in general, treated by surgical resection, but may require a little or at times more significant reconstruction. Among these tumors, the myxomas are associated with a higher rate of recurrences...