Philip AinslieSummaryAffiliation: University of Calgary Country: Canada Publications
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Physiological and metabolic aspects of very prolonged exercise with particular reference to hill walkingPhilip N Ainslie
Department of Physiology and Biophysics, University of Calgary, Faculty of Medicine, Calgary, Canada
Sports Med 35:619-47. 2005..Periods of adverse weather, low energy intake, lowered fitness or increased age, can all increase the participants' susceptibility to injury, fatigue and hypothermia in the mountainous environment...- Estimating human energy expenditure: a review of techniques with particular reference to doubly labelled waterPhilip Ainslie
Department of Physiology and Biophysics, University of Calgary, Faculty of Medicine, Heritage Medical Research Building Room 209, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
Sports Med 33:683-98. 2003..A consideration of the relevant techniques used for the estimation of EE may also help improve the quality of these frequently reported measurements... - Effect of five nights of normobaric hypoxia on cardiovascular responses to acute isocapnic hypoxia in humans: relationship to ventilatory chemosensitivityPhilip N Ainslie
Department of Physiology and Biophysics, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
Ergonomics 48:1523-34. 2005..The relationship between the enhanced AHVR and MAP sensitivity raises the possibility of a common pathway in the regulation of peripheral chemosensitivity and MAP responses during periods of isocapnic hypoxia... - Alterations in cerebral autoregulation and cerebral blood flow velocity during acute hypoxia: rest and exercisePhilip N Ainslie
Department of Physiology, University of Otago, Dunedin, New Zealand
Am J Physiol Heart Circ Physiol 292:H976-83. 2007..Despite maintaining MCAV, such hypoxic exercise can potentially compromise cerebral autoregulation and oxygenation... - Cardiorespiratory and cerebrovascular responses to acute poikilocapnic hypoxia following intermittent and continuous exposure to hypoxia in humansPhilip N Ainslie
Dept of Physiology, University of Otago, Dunedin, New Zealand
J Appl Physiol 102:1953-61. 2007..Our findings indicate that IH and/or mild CH can equally enhance the HVR, which, by either direct or indirect mechanisms, facilitates alterations in BP and MCAV... - Morning attenuation in cerebrovascular CO2 reactivity in healthy humans is associated with a lowered cerebral oxygenation and an augmented ventilatory response to CO2Kevin J Cummings
Dept of Zoology, LaTrobe University, Melbourne, Australia
J Appl Physiol 102:1891-8. 2007.... - Alterations in autonomic function and cerebral hemodynamics to orthostatic challenge following a mountain marathonCarissa Murrell
Department of Physiology, University of Otago, Dunedin, New Zealand
J Appl Physiol 103:88-96. 2007..Such changes may be critical factors in collapse following prolonged exercise... - Effects of intermittent hypoxia on SaO(2), cerebral and muscle oxygenation during maximal exercise in athletes with exercise-induced hypoxemiaHelen C Marshall
Lincoln University, Christchurch, Canterbury 7647, New Zealand
Eur J Appl Physiol 104:383-93. 2008..We speculate that the unchanged VO(2peak) following IHE might reflect a balance between these central (cerebral) and peripheral (muscle) adaptations... - Differential effects of acute hypoxia and high altitude on cerebral blood flow velocity and dynamic cerebral autoregulation: alterations with hyperoxiaPhilip N Ainslie
Dept of Physiology, Univ of Otago, Dunedin, New Zealand
J Appl Physiol 104:490-8. 2008..05). Findings indicate that hyperoxia at HA can partially improve CA and lower BP, with little effect on MCAv... - Cardiorespiratory and cerebrovascular responses to hyperoxic and hypoxic rebreathing: effects of acclimatization to high altitudePhilip N Ainslie
Department of Physiology, University of Otago, Dunedin, New Zealand
Respir Physiol Neurobiol 161:201-9. 2008.... - Mechanisms of orthostatic intolerance following very prolonged exerciseSamuel J E Lucas
School of Physical Education, University of Otago, Dunedin, New Zealand
J Appl Physiol 105:213-25. 2008..Recovery was complete within 48 h. During prolonged exercise, postural-induced hypotension and hypocapnia exacerbate cerebral hypoperfusion and facilitate syncope... - Physiological, metabolic, and performance implications of a prolonged hill walk: influence of energy intakePhilip N Ainslie
Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1
J Appl Physiol 94:1075-83. 2003..The modestly impaired performance (particularly with respect to balance) and thermoregulation during the LEI condition may increase susceptibility to both fatigue and injury during the pursuit of recreational activity outdoors... - Differential responses to CO2 and sympathetic stimulation in the cerebral and femoral circulations in humansPhilip N Ainslie
Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
J Physiol 566:613-24. 2005..In contrast, HG increased FVR during conditions of ISO, HC5 and HC10. Therefore, the cerebral circulation is more responsive to alterations in PCO2, and less responsive to sympathetic stimulation than the femoral circulation... - Ventilatory, cerebrovascular, and cardiovascular interactions in acute hypoxia: regulation by carbon dioxidePhilip N Ainslie
Department of Physiology and Biophysics, Faculty of Medicine, Univiversity of Calgary, Calgary Alberta, Canada T2N 4N1
J Appl Physiol 97:149-59. 2004..In summary, the between-individual variability in AHVR is shown to be firmly linked to the variability in V(p) and MAP responses to hypoxia. Individuals with a high AHVR are found also to have high V(p) and MAP responses to hypoxia... - Human cerebral arteriovenous vasoactive exchange during alterations in arterial blood gasesKaren C Peebles
Department of Physiology, University of Otago, Dunedin, New Zealand
J Appl Physiol 105:1060-8. 2008..05). These data indicate that there is a differential exchange of NO across the brain during hypercapnia and hypoxia and that CNP may play a complementary role in CO(2)-induced CBF changes... - Effects of five nights of normobaric hypoxia on the ventilatory responses to acute hypoxia and hypercapniaPhilip N Ainslie
Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Heritage Medical Research Building Room 209, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
Respir Physiol Neurobiol 138:193-204. 2003..7 +/- 4.3 Torr; P<0.05) of the AHCVR. These results show that five nights of hypoxia can elicit similar perturbations, in both AHVR and AHCVR, as have been reported during more chronic altitude exposures... - Effects of five consecutive nocturnal hypoxic exposures on the cerebrovascular responses to acute hypoxia and hypercapnia in humansJon C Kolb
Faculty of Kinesiology, Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada T2N 4N1
J Appl Physiol 96:1745-54. 2004..94 +/- 0.04). These results show that discontinuous hypoxia elicits increases in the sensitivity of CBF to acute variations in O2 and CO2, which are similar to those observed during chronic hypoxia... - Multivariate system identification for cerebral autoregulationTingying Peng
Department of Engineering Science, University of Oxford, Oxford, OX1 3PJ, UK
Ann Biomed Eng 36:308-20. 2008..Finally, a physiologically based model and its linear transfer function are used as a simulation tool to investigate possible causes of low univariate coherence... - Protocol to measure acute cerebrovascular and ventilatory responses to isocapnic hypoxia in humansJon C Kolb
Faculty of Kinesiology, University of Calgary, Calgary, Alta, T2N 4N1, Canada
Respir Physiol Neurobiol 141:191-9. 2004..Coefficients of variation for AHR(CBF), AHRSr(O2) and AHVR were small (range = 8.0-15.2%). This protocol appears suitable to quantify cerebrovascular and ventilatory responses to acute isocapnic hypoxia... - Human cerebrovascular and ventilatory CO2 reactivity to end-tidal, arterial and internal jugular vein PCO2Karen Peebles
Department of Physiology, University of Otago, Dunedin, New Zealand
J Physiol 584:347-57. 2007..Differences in the P(ET,CO(2)), P(a,CO(2)) and P(jv,CO(2))-MCAv relationships have implications for the true representation and physiological interpretation of cerebrovascular CO(2) reactivity... - Evidence against redox regulation of energy homoeostasis in humans at high altitudeDamian M Bailey
Colorado Center for Altitude Medicine and Physiology, Departments of Anesthesiology and Surgery, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Clin Sci (Lond) 107:589-600. 2004..Thus free radicals do not appear to be involved in the inflammatory response and subsequent control of eating behaviour at high altitude... - Respiratory, cerebrovascular and pressor responses to acute hypoxia: dependency on PET(CO2)Philip N Ainslie
Departments of Physiology and Biophysics, University of Calgary, Calgary Alberta, T2N 4N1 Canada
Adv Exp Med Biol 551:243-9. 2004 - Nonlinear modeling of the dynamic effects of arterial pressure and blood gas variations on cerebral blood flow in healthy humansGeorgios D Mitsis
Department of Biomedical Engineering, University of Southern California, University Park, Los Angeles, CA 90089-1451, USA
Adv Exp Med Biol 551:259-65. 2004 - Alterations in cerebral dynamics at high altitude following partial acclimatization in humans: wakefulness and sleepPhilip N Ainslie
Dept of Physiology, Univ of Otago, Dunedin, New Zealand
J Appl Physiol 102:658-64. 2007..05 vs. low altitude). Lowered cerebrovascular reactivity to CO2 and reduction in both dynamic cerebral autoregulation and MCAv during sleep at high altitude may be factors in the pathogenesis of breathing instability... - Effects of 5 consecutive nocturnal hypoxic exposures on respiratory control and hematogenesis in humansJon C Kolb
Faculty of Kinesiology, and Departments of Physiology and Biophysics and Clinical Neurosciences, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1 Canada
Adv Exp Med Biol 551:305-10. 2004 - Elevation in cerebral blood flow velocity with aerobic fitness throughout healthy human ageingPhilip N Ainslie
Department of Physiology, University of Otago, Dunedin, New Zealand
J Physiol 586:4005-10. 2008..The persistence of this finding in older endurance-trained men may therefore help explain why there is a lower risk of cerebrovascular disease in this population...