Research Topics
| Christopher S ParshuramSummaryAffiliation: The Hospital for Sick Children Country: Canada Publications
| Collaborators
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Detail Information
Publications
Development and initial validation of the Bedside Paediatric Early Warning System scoreChristopher S Parshuram
Department of Critical Care Medicine, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
Crit Care 13:R135. 2009..Identification of children for referral to critical care experts remains problematic. Our objective was to develop and validate a simple bedside score to quantify severity of illness in hospitalized children...- Pharmacotherapeutic friendly fire in the intensive care unit: high stakes seeking high calibreChristopher S Parshuram
Department of Critical Care Medicine, Hospital for Sick Children, Toronto, Ontario, Canada
Crit Care 12:137. 2008.... - Systematic evaluation of errors occurring during the preparation of intravenous medicationChristopher S Parshuram
Department of Critical Care Medicine, and the Center for Safety Research, Child Health Evaluative Sciences Program, The Research Institute, The Hospital for Sick Children, Toronto, Ont
CMAJ 178:42-8. 2008..Errors in the concentration of intravenous medications are not uncommon. We evaluated steps in the infusion-preparation process to identify factors associated with preventable medication errors... - The impact of fatigue on patient safetyChristopher S Parshuram
Department of Critical Care Medicine, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
Pediatr Clin North Am 53:1135-53. 2006..Appropriate evaluations are essential if well-meaning but larger scale errors in the name of patient safety are to be avoided... - Pharmacotherapy in pediatric critical illness: a prospective observational studyConor McDonnell
Department of Critical Care Medicine, Hospital for Sick Children, University of Toronto, Ontario, Canada
Paediatr Drugs 11:323-31. 2009..In order to better understand pharmacotherapy in pediatric critical illness, we evaluated a cohort of emergency admissions to a university-affiliated pediatric intensive care unit (PICU)... - A cross-sectional survey of levels of care and response mechanisms for evolving critical illness in hospitalized childrenStephanie D VandenBerg
Department of Critical Care Medicine, Research Institute, Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Pediatrics 119:e940-6. 2007..We describe here the levels of care, the frequency of near or actual cardiopulmonary arrest (code-blue events), identification mechanisms, and responses to evolving critical illness in hospitalized children... - Documentation of pediatric drug safety in manufacturers' product monographs: a cross-sectional evaluation of the canadian compendium of pharmaceuticals and specialitiesNavjeet K Uppal
Department of Critical Care Medicine, Hospital for Sick Children, Toronto, Ontario, Canada
Paediatr Drugs 10:193-7. 2008..To describe the provision of pediatric drug safety information in a national formulary of manufacturers' drug product monographs... - Occurrence and impact of unanticipated variation in intravenous methotrexate dosingChristopher S Parshuram
Department of Critical Care Medicine, Hospital for Sick Children Toronto, ON, Canada
Ann Pharmacother 40:805-11. 2006..Subsequent studies in this model of dosing error will require larger sample sizes, and other drugs should be evaluated... - Hypothermia therapy after pediatric cardiac arrestDermot R Doherty
Department of Anaesthesia, Division of Pediatric Intensive Care, Children s Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada
Circulation 119:1492-500. 2009..Hypothermia therapy improves mortality and functional outcome after cardiac arrest and birth asphyxia in adults and newborns. The effect of hypothermia therapy in infants and children with cardiac arrest is unknown... - Prospective evaluation of residents on call: before and after duty-hour reductionZia Bismilla
Department of Paediatrics, Research Institute, Toronto, Ontario, Canada
Pediatrics 127:1080-7. 2011..We evaluated the effect of regulation on residents in 3 eras: 2 before (2005 and early 2009) and 1 after (late 2009) the duty-hour reduction... - Quantifying the volume of documented clinical information in critical illnessOrit Manor-Shulman
Department of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
J Crit Care 23:245-50. 2008..The purpose of this study is to describe the volume of clinical information documented in critical illness, its relationship to the use of intensive care unit (ICU) technology, and changes over time... - Prolonged time to alarm in infusion devices operated at low flow ratesRoy Ilan
Department of Medicine, Queen s University and Kingston General Hospital, Kingston, ON, Canada
Crit Care Med 36:2763-5. 2008..To evaluate the time to occlusion alarm for peristaltic infusion devices used in Toronto adult critical care units... - Discrepancies between ordered and delivered concentrations of opiate infusions in critical careChristopher S Parshuram
Department of Critical Care Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
Crit Care Med 31:2483-7. 2003..These findings are likely to be broadly representative of intravenous drug administration in hospitalized children and pediatric pharmacokinetic studies. Further study of the causes and clinical impact is required... - In-house, overnight physician staffing: a cross-sectional survey of Canadian adult and pediatric intensive care unitsChristopher S Parshuram
Department of Critical Care Medicine and Division of Clinical Pharmacology, Population Health Sciences, The Research Institute, The Hospital for Sick Children, Toronto, and McMaster University, Hamilton, Ontario, Canada
Crit Care Med 34:1674-8. 2006..The duration of most ICU shifts raises concern about workload-associated fatigue and medical error. The impact of current nighttime staffing requires further evaluation with respect to patient outcomes... - Multicentre validation of the bedside paediatric early warning system score: a severity of illness score to detect evolving critical illness in hospitalised childrenChristopher S Parshuram
Department of Critical Care Medicine, Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada
Crit Care 15:R184. 2011..The objective of this study was to validate the Bedside PEWS score in a large patient population at multiple hospitals... - Fellowship training, workload, fatigue and physical stress: a prospective observational studyChristopher S Parshuram
Department of Critical Care Medicine, Hospital for Sick Children, Tornto, ON
CMAJ 170:965-70. 2004..Anecdotal evidence suggests that the on-call workload and physical demands experienced by trainees are significant despite duty-hour regulation and support from nursing staff, other trainees and staff physicians... - Use of milrinone in critically ill childrenTeresa Bishara
Staff Pharmacist with the Department of Pharmacy, North York General Hospital, Toronto, Ontario
Can J Hosp Pharm 63:420-8. 2010..Optimal dose adjustment of milrinone in critically ill children is challenging because of conflicting information about the association between dose and outcomes in this age group... - Parental attitudes to digital recording: A paediatric hospital surveyKatherine Taylor
Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada
J Paediatr Child Health 47:335-9. 2011..As participants in this process, the perspectives of families are important to inform practice. We surveyed family members of hospitalized children to evaluate their opinions... - Pediatric in-intensive-care-unit cardiac arrest: incidence, survival, and predictive factorsNienke de Mos
Department of Critical Care Medicine, Toronto, Ontario, Canada
Crit Care Med 34:1209-15. 2006..The use of post-arrest ECMO within 24 hrs was associated with reduced mortality. Rigorous prospective evaluation of the role of ECMO following cardiac arrest is needed... - Have changes in ventilation practice improved outcome in children with acute lung injury?Waleed H Albuali
Department of Pediatrics and Pediatric Critical Care Unit, Children s Hospital of Western Ontario, London Health Sciences Center, University of Western Ontario, London, ON, Canada
Pediatr Crit Care Med 8:324-30. 2007.... - The Pediatric Early Warning System score: a severity of illness score to predict urgent medical need in hospitalized childrenHeather Duncan
Paediatric Intensive Care Unit, Diana, Princess of Wales Children's Hospital, Steelhouse Lane, B4 6NH Birmingham, UK
J Crit Care 21:271-8. 2006..After further refinement and validation, the PEWS score has great potential to increase the efficiency of care delivery and to improve the outcomes of care provided to hospitalized children... - Learning in patient-based education sessions: a prospective evaluationMegan R Smith
Nottingham University Hospital Trust, Nottingham, UK
Pediatr Crit Care Med 9:86-90. 2008..The objective was to evaluate the impact of in-house call on cognitive attention, learning, and recall of critical care medicine trainees, before and after a reduction in call period...