Research Topics
Species | Iwona RudkowskaSummaryCountry: Canada Publications
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Detail Information
Publications
Functional foods for health: focus on diabetesIwona Rudkowska
Lipid Research Center, CHUQ CHUL Pavilion, Quebec, Canada
Maturitas 62:263-9. 2009....
Functional foods for cardiovascular disease in womenIwona Rudkowska
Lipid Research Center, CHUQ CHUL, 2705 Laurier Blvd, TR 93, Quebec, Canada, G1V 4G2
Menopause Int 14:63-9. 2008..Overall, incorporating functional foods into a healthy diet may be beneficial in helping to reduce lipids levels and thus the risk of CVD...
Fish oils for cardiovascular disease: Impact on diabetesIwona Rudkowska
Lipid Research Center, CHUQ CHUL Pavilion, Laval University, 2705 Laurier Blvd, TR 93, Quebec, Quebec, Canada G1V 4G2
Maturitas 67:25-8. 2010..Overall, n-3 PUFA supplementation represents a reasonable therapeutic strategy in individuals with T2DM to decrease the risk of complications...
Plant sterols and stanols for healthy ageingIwona Rudkowska
Lipid Research Center, CHUQ CHUL Pavilion, Quebec, Quebec, Canada
Maturitas 66:158-62. 2010..Overall, dietary intervention strategies, such as incorporating PS into a healthy diet, should be recommended and implemented in older adult populations in order to prevent ageing-associated diseases and hence promote healthy ageing...
PPARalpha L162V polymorphism alters the potential of n-3 fatty acids to increase lipoprotein lipase activityIwona Rudkowska
Lipid Research Center, CHUL Research Center, Sainte Foy, Quebec, Canada
Mol Nutr Food Res 54:543-50. 2010..Overall, these results indicate that n-3 FA supplementation increases the transcription rate of LPL to a greater extent in L162-PPARalpha than V162-PPARalpha...
Effects of a supplementation of n-3 polyunsaturated fatty acids with or without fish gelatin on gene expression in peripheral blood mononuclear cells in obese, insulin-resistant subjectsIwona Rudkowska
Institute of Nutraceuticals and Functional Foods INAF, Laval University, Quebec, Quebec, Canada
J Nutrigenet Nutrigenomics 4:192-202. 2011..To investigate gene expression changes in peripheral blood mononuclear cells (PBMCs) following an n-3 polyunsaturated fatty acid (PUFA) and n-3 PUFA plus fish gelatin (+FG) supplementation...
Cholesterol-lowering efficacy of plant sterols in low-fat yogurt consumed as a snack or with a mealIwona Rudkowska
School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Ste Anne de Bellevue, Quebec, Canada
J Am Coll Nutr 27:588-95. 2008..6 g/d) with a meal over an afternoon snack will lead to favourable changes in plasma lipids, plasma PS concentrations, and cholesterol synthesis without negatively affecting alpha-tocopherol or carotenoids levels...
Validation of the use of peripheral blood mononuclear cells as surrogate model for skeletal muscle tissue in nutrigenomic studiesIwona Rudkowska
Institute of Nutraceuticals and Functional Foods INAF, Laval University, Quebec, Canada
OMICS 15:1-7. 2011..Further research on PBMC and SMT gene expression in response to other nutritional exposures is warranted...
Fish nutrients decrease expression levels of tumor necrosis factor-alpha in cultured human macrophagesIwona Rudkowska
Lipid Research Center, CHUL Research Center, and Nutraceuticals and Functional Foods Institute INAF, Laval University, Quebec City, Quebec, Canada G1V 4G2
Physiol Genomics 40:189-94. 2010..Hence, follow-up studies should be performed to confirm the effects of a diet rich in FPH and omega-3 FA on serum proinflammatory cytokine concentrations...
Effect of the PPAR-Alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 polyunsaturated fatty acidsDominique Caron-Dorval
Lipid Research Center, CHUQ CHUL Pavilion, Quebec, Canada
J Nutrigenet Nutrigenomics 1:205-12. 2008..Since fatty acids, including n-3 PUFAs, are natural ligands of PPARalpha, a gene-diet interaction effect could be observed...
Omega-3 fatty acids regulate gene expression levels differently in subjects carrying the PPARalpha L162V polymorphismIwona Rudkowska
Lipid Research Center, CHUL Research Center, The Nutraceuticals and Functional Foods Institute INAF, Quebec, Canada
Genes Nutr 4:199-205. 2009..Consequently, individuals carrying the PPARalpha-V162 allele may demonstrate inferior improvements in their lipid profile due to alterations in gene expression rates in response to omega-3 FA supplementation...
Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone diseaseIwona Rudkowska
School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Ste Anne de Bellevue, Quebec, Canada
Nutr Rev 66:343-8. 2008..Clearly, the ABCG5 and ABCG8 genes play an important role in cholesterol homeostasis. However, more research is needed to establish how specific polymorphisms of these genes confer to higher risk of these diseases...
Functional foods for the prevention and treatment of cardiovascular diseases: cholesterol and beyondIwona Rudkowska
School of Dietetics and Human Nutrition McGill University, St Anne de Bellevue, Quebec, Canada
Expert Rev Cardiovasc Ther 5:477-90. 2007..Overall, these functional foods should be considered as an addition to current lipid-lowering recommendations for improving CVD risk...
Differences in Transcriptional Activation by the Two Allelic (L162V Polymorphic) Variants of PPARalpha after Omega-3 Fatty Acids TreatmentIwona Rudkowska
Lipid Research Center, CHUL Research Center, QC, Canada G1V 4G2
PPAR Res 2009:369602. 2009..In conclusion, both allelic variants of the PPARalpha L162V are activated by omega-3 FAs; however, the V162 allelic form displays a lower transcriptional activity than the wild-type variant...
Phytosterols mixed with medium-chain triglycerides and high-oleic canola oil decrease plasma lipids in overweight menIwona Rudkowska
School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, , Canada H9X 3V9
Metabolism 55:391-5. 2006....
