Research Topics
| Matthew W GilmourSummaryAffiliation: Public Health Agency of Canada Country: Canada Publications
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Detail Information
Publications
Multilocus sequence typing of Escherichia coli O26:H11 isolates carrying stx in canada does not identify genetic diversityMatthew W Gilmour
Emerging Bacterial Pathogens Program, National Microbiology Laboratory, Winnipeg, Manitoba, Canada
J Clin Microbiol 43:5319-23. 2005....- Genetic characterization of clinical and agri-food isolates of multi drug resistant Salmonella enterica serovar Heidelberg from CanadaAshleigh K Andrysiak
Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada
BMC Microbiol 8:89. 2008..Heidelberg in chicken agri-food sources and the simultaneous increase of MDR S. Heidelberg in human clinical samples... - Use of the espZ gene encoded in the locus of enterocyte effacement for molecular typing of shiga toxin-producing Escherichia coliMatthew W Gilmour
National Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, Canada
J Clin Microbiol 44:449-58. 2006..The study focused on the characterization of three clinically significant seropathotypes of LEE-positive STEC, and we have used the observed genetic variation at a pathogen-specific locus for detection and subtyping of STEC... - Sequence-based typing of genetic targets encoded outside of the O-antigen gene cluster is indicative of Shiga toxin-producing Escherichia coli serogroup lineagesMatthew W Gilmour
National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada
J Med Microbiol 56:620-8. 2007.... - High-throughput genome sequencing of two Listeria monocytogenes clinical isolates during a large foodborne outbreakMatthew W Gilmour
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada
BMC Genomics 11:120. 2010..monocytogenes isolates was used to rapidly provide the genome sequence of the primary outbreak strain and to investigate the extent of genetic diversity associated with a change of a single restriction enzyme fragment during PFGE... - Molecular typing of a Legionella pneumophila outbreak in Ontario, CanadaMatthew W Gilmour
National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada
J Med Microbiol 56:336-41. 2007..These molecular typing methods confirmed the outbreak source as a contaminated air conditioning cooling tower... - Rapid detection of Vibrio species using liquid microsphere arrays and real-time PCR targeting the ftsZ locusDobryan M Tracz
National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada
J Med Microbiol 56:56-65. 2007..cholerae, V. parahaemolyticus and V. vulnificus. These assays permitted the identification of a presumptive V. parahaemolyticus isolate as Vibrio alginolyticus, which was verified using additional molecular characterization... - Limited genetic diversity in Salmonella enterica serovar Enteritidis PT13Adam B Olson
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada
BMC Microbiol 7:87. 2007..Enteritidis PT13... - Isolation and genetic characterization of a coinfection of non-O157 Shiga toxin-producing Escherichia coliMatthew W Gilmour
National Microbiology Laboratory, Winnipeg, Manitoba, Canada
J Clin Microbiol 45:3771-3. 2007..However, both STEC serotypes are known to cause serious disease, and the significant repertoire of virulence determinants in both strains made it impossible to determine their individual contributions to the clinical symptoms... - Genetic determinants and polymorphisms specific for human-adapted serovars of Salmonella enterica that cause enteric feverDobryan M Tracz
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
J Clin Microbiol 44:2007-18. 2006..These determinants provided phylogenetic data on the genetic relatedness of serovars Typhi, Paratyphi A, and Sendai; and the protocols developed might allow the rapid identification of these Salmonella serovars that cause enteric fever... - Comparative genomics of Vibrio cholerae from Haiti, Asia, and AfricaAleisha R Reimer
Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Emerg Infect Dis 17:2113-21. 2011..However, because no identical genetic match was found among sequenced contemporary isolates, a definitive genetic origin for the outbreak in Haiti remains speculative... - Isolation and detection of Shiga toxin-producing Escherichia coli in clinical stool samples using conventional and molecular methodsMatthew W Gilmour
National Microbiology Laboratory, Winnipeg, MN, Canada
J Med Microbiol 58:905-11. 2009..This toolbox of molecular methods provided robust detection capabilities for STEC in clinical stool samples, including co-infection of multiple serogroups... - Phylogenetic relationships of Campylobacter jejuni based on porA sequencesClifford G Clark
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB
Can J Microbiol 53:27-38. 2007..Different MOMP sequence groups may have different biological or antigenic properties, which in turn may be associated with survival in different environments, host adaptation, or virulence... - Vibrio cholerae in Traveler from Haiti to CanadaMatthew W Gilmour
Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Emerg Infect Dis 17:1124-5. 2011..In these instances, illness was related to travel to Haiti or consumption of contaminated water on the island of Hispaniola (which is shared by Haiti and Dominican Republic)... - Interaction between the co-inherited TraG coupling protein and the TraJ membrane-associated protein of the H-plasmid conjugative DNA transfer system resembles chromosomal DNA translocasesJames E Gunton
Department of Medical Microbiology and Immunology, 1 63 Medical Sciences Building, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
Microbiology 153:428-41. 2007..It is proposed that TraJ is a functional part of the IncH-type coupling protein complex required for translocation of DNA through the cytoplasmic membrane... - The complete nucleotide sequence of the resistance plasmid R478: defining the backbone components of incompatibility group H conjugative plasmids through comparative genomicsMatthew W Gilmour
Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alta, Canada T6G 2R3
Plasmid 52:182-202. 2004..The similarity to a diverse set of bacterial sequences highlights the ability of horizontally transferable DNA elements to acquire and disseminate genetic traits through the bacterial gene pool... - Interaction between the IncHI1 plasmid R27 coupling protein and type IV secretion system: TraG associates with the coiled-coil mating pair formation protein TrhBMatthew W Gilmour
Department of Medical Microbiology, 1-28 Medical Sciences Building, University of Alberta, Edmonton, Canada T6G 2R3
Mol Microbiol 49:105-16. 2003..These data support a model in which the coupling protein interacts with an Mpf component to target the transferring DNA strand held by the relaxosome to the transmembrane Mpf complex... - Functional and mutational analysis of conjugative transfer region 2 (Tra2) from the IncHI1 plasmid R27Trevor D Lawley
Department of Biological Sciences, University of Alberta, Edmonton, Canada T6G 2R3
J Bacteriol 185:581-91. 2003..Furthermore, the Mpf/type IV secretion systems encoded by IncH and IncF transfer systems are distinct from that of the IncP transfer system. The phenotypic and ecological significance of these observations is discussed... - Subcellular localization and functional domains of the coupling protein, TraG, from IncHI1 plasmid R27James E Gunton
Department of Medical Microbiology and Immunology, 1-63 Medical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2R3
Microbiology 151:3549-61. 2005..These results allow the definition of domains within TraG that are involved in conjugative transfer, and determination of the cellular location of the R27 coupling protein... - A subassembly of R27-encoded transfer proteins is dependent on TrhC nucleoside triphosphate-binding motifs for function but not formationMatthew W Gilmour
Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta T6G 2R3, Canada
J Bacteriol 186:1606-13. 2004..These results indicate that TrhC requires intact NTP-binding motifs to function during conjugative transfer but that these motifs are not essential for the assembly of TrhC into a complex with other transfer proteins... - Functional and mutational analysis of conjugative transfer region 1 (Tra1) from the IncHI1 plasmid R27Trevor D Lawley
Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2R3
J Bacteriol 184:2173-80. 2002..This analysis indicates that the Mpf components of R27 share a common lineage with those of the IncF transfer system, whereas the relaxase of R27 is ancestrally related to that of the IncP transfer system...