Research Topics
| M OuelletteSummaryCountry: Canada Publications
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Detail Information
Publications
Biochemical and molecular mechanisms of drug resistance in parasitesM Ouellette
Centre de Recherche en Infectiologie du Centre de Recherche du CHUL and Département de Microbiologie, Faculte de Medecine, Universite Laval, Quebec, Canada
Trop Med Int Health 6:874-82. 2001..Understanding drug resistance is essential for the control of parasitic diseases...
Multidrug resistance and ABC transporters in parasitic protozoaM Ouellette
Centre de Recherche en Infectiologie du Centre de Recherche du CHUL and Département de Microbiologie, Faculte de Medecine, Universite Laval, Ste Foy, Quebec, Canada
J Mol Microbiol Biotechnol 3:201-6. 2001..We review here the role of ABC transporters in drug resistance in parasites. We have concentrated on gene and gene products for which there is a strong evidence for their role in resistance...
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in LeishmaniaW Moreira
Centre de Recherche en Infectiologie du CHUL, Universite Laval, Quebec, Quebec, Canada
Cell Death Dis 2:e201. 2011..Our results therefore link the mode of killing of drugs to tolerance to cell death and to a facilitated emergence of multidrug resistance. These findings may have fundamental implications in the field of chemotherapeutic interventions...
