Research Topics
| C van WalravenSummaryAffiliation: Ottawa Health Research Institute Country: Canada Publications
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Publications
Administrative database research has unique characteristics that can risk biased resultsCarl van Walraven
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario K1Y 4E9, Canada
J Clin Epidemiol 65:126-31. 2012....
Does adding risk-trends to survival models improve in-hospital mortality predictions? A cohort studyJenna Wong
Clinical Epidemiology Program, Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, K1Y 4E9, Canada
BMC Health Serv Res 11:171. 2011..In this study, we used a unique approach to measure trends in patient hospital death risk and determined whether the incorporation of these trend measures into a survival model improved the accuracy of its risk predictions...
Anticoagulation control in the peri-hospitalization periodCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute C404, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada
J Gen Intern Med 22:727-35. 2007..Anticoagulated patients discharged after medical hospitalizations could be targeted for improved anticoagulation control...
Continuity of care and patient outcomes after hospital dischargeCarl van Walraven
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Gen Intern Med 19:624-31. 2004..Transfer of information between physicians can be poor. We determined whether early postdischarge outcomes changed when patients were seen after discharge by physicians who treated them in the hospital...
The usefulness of administrative databases for identifying disease cohorts is increased with a multivariate modelCarl van Walraven
Clinical Epidemiology Program, Ottawa Hospital Research Institute, F660 1053 Carling Avenue, Ottawa, Ontario, Canada
J Clin Epidemiol 63:1332-41. 2010..This would allow the accurate identification of a disease cohort in an administrative database...
Oral anticoagulants vs. aspirin for stroke prevention in patients with non-valvular atrial fibrillation: the verdict is inCarl van Walraven
Clinical Epidemiology Unit Ottawa Health Research Institute, Ottawa, Ontario, Canada
Card Electrophysiol Rev 7:374-8. 2003..Since high-risk AF patients appear to benefit most from OAC, determining stroke risk in AF patients is very important...
Incidence, follow-up, and outcomes of incidental abdominal aortic aneurysmsCarl van Walraven
Faculty of Medicine, University of Ottawa, Ontario, Canada
J Vasc Surg 52:282-9.e1-2. 2010..Incidental AAAs are important findings because they require monitoring and surgical treatment, when indicated, to prevent rupture. The prevalence of incidental AAAs and their management has not been extensively studied...
The association between continuity of care and outcomes: a systematic and critical reviewCarl van Walraven
Department of Medicine, University of Ottawa, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada
J Eval Clin Pract 16:947-56. 2010..Studies doing so must actually measure continuity. If continuity and outcomes are measured concurrently, their association can only be determined with time-dependent methods...
Population-based study of repeat laboratory testingCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, C405, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ON K1Y 4E9, Canada
Clin Chem 49:1997-2005. 2003..Laboratory test repetition has not been rigorously studied at a population-based level. Our objective was to determine the prevalence of, and charges associated with, repetition of eight common laboratory tests...
A prospective cohort study found that provider and information continuity was low after patient discharge from hospitalCarl van Walraven
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Clin Epidemiol 63:1000-10. 2010..This study is a detailed examination of continuity of care in patients discharged from hospital that simultaneously measured separate components of continuity over time or determined the factors with which they are associated...
Derivation and validation of a MEDLINE search strategy for research studies that use administrative dataCarl van Walraven
Ottawa Hospital Research Institute, Institute for Clinical Evaluative Sciences, ASB 1 003 1053 Carling Avenue, Ottawa, ON
Health Serv Res 45:1836-45. 2010..To derive and validate a search strategy that identifies administrative database research (ADR) in the MEDLINE database...
Time-dependent bias was common in survival analyses published in leading clinical journalsCarl van Walraven
Department of Medicine, University of Ottawa, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, F 660, Ottawa, ON K1Y 4E9, Canada
J Clin Epidemiol 57:672-82. 2004..Time-dependent bias can occur if such variables are not analyzed appropriately. This study sought to determine the prevalence of such time-dependent bias in highly-cited medical journals...
Predicting potential survival benefit of renal transplantation in patients with chronic kidney diseaseCarl van Walraven
Faculty of Medicine, University of Ottawa, Ont
CMAJ 182:666-72. 2010..To facilitate decision-making about treatment options for patients with end-stage renal disease considering kidney transplantation, we sought to develop an index for clinical prediction of risk for death...
Burden of potentially avoidable anticoagulant-associated hemorrhagic and thromboembolic events in the elderlyCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, Ontario, Canada
Chest 131:1508-15. 2007..However, not all anticoagulation-associated events are attributable to poor anticoagulation control, nor do all hemorrhagic or thromboembolic events occur in anticoagulated patients...
Information exchange among physicians caring for the same patient in the communityCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, ASB1 003, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ONK1Y4E9
CMAJ 179:1013-8. 2008..This study determined the probability that patient information from previous visits with other physicians was available for a current physician visit...
Effect of provider continuity on test repetitionCarl van Walraven
Network of Eastern Ontario Medical Laboratories NEO MeL, Ottawa, ONT Canada
Clin Chem 52:2219-28. 2006..A perceived benefit of PC is decreased test repetition. Repeat tests make up a significant proportion of overall laboratory utilization. This study determined whether test repetition increases when PC decreases...
Effect of age on stroke prevention therapy in patients with atrial fibrillation: the atrial fibrillation investigatorsCarl van Walraven
University of Ottawa and Ottawa Health Research Institute Canada, Ottawa, Canada
Stroke 40:1410-6. 2009....
Effect of study setting on anticoagulation control: a systematic review and metaregressionCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, C405, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ON, K1Y 4E9 Canada
Chest 129:1155-66. 2006..The effect of study-level factors, especially study setting, on anticoagulation control is unknown...
A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative dataCarl van Walraven
Ottawa Health Research Institute, Ottawa, Ontario, Canada
Med Care 47:626-33. 2009..However, the Elixhauser classification system requires 30 binary variables, making its use for reporting and analysis of comorbidity cumbersome...
Correlation between serial tests made disease probability estimates erroneousCarl van Walraven
Ottawa Health Research Institute, Ontario, Canada
J Clin Epidemiol 62:1301-5. 2009..The probability of a disease, given the result of two diagnostic tests, can be calculated by multiplying the odds of disease after the first test by the likelihood ratio of the second test...
The Kaiser Permanente inpatient risk adjustment methodology was valid in an external patient populationCarl van Walraven
Ottawa Health Research Institute, A581 003 Carling Ave, Ottawa, Ontario K1Y 4E9, Canada
J Clin Epidemiol 63:798-803. 2010..This study assessed the Kaiser Permanente inpatient risk adjustment methodology for hospital mortality in a patient population distinct from that used for its derivation...
Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the communityCarl van Walraven
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa Hospital, and the Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario
CMAJ 182:551-7. 2010..We sought to derive and validate an index to predict the risk of death or unplanned readmission within 30 days after discharge from hospital to the community...
A clinical prediction rule to identify patients with atrial fibrillation and a low risk for stroke while taking aspirinCarl van Walraven
Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa Hospital, Ontario, Canada
Arch Intern Med 163:936-43. 2003....
Proportion of hospital readmissions deemed avoidable: a systematic reviewCarl van Walraven
Faculty of Medicine, University of Ottawa, Ottawa, Ont
CMAJ 183:E391-402. 2011..We conducted a systematic review of studies that measured the proportion of readmissions deemed avoidable. We examined how such readmissions were measured and estimated their prevalence...
The effect of participation in a weight loss programme on short-term health resource utilizationCarl van Walraven
Department of Medicine, Institute for Clinical Evaluative Sciences, University of Ottawa, Ottawa, Ontario, Canada
J Eval Clin Pract 8:37-44. 2002..Further study is required to determine if patients who maintain their weight loss experience a decrease in health utilization...
Radiographic monitoring of incidental abdominal aortic aneurysms: a retrospective population-based cohort studyCarl van Walraven
University of Ottawa, Canada
Open Med 5:e67-76. 2011..No population-based studies have assessed the management of incidental AAAs. The objective of this study was to measure the completeness of radiographic monitoring of incidental AAAs by means of a population-based analysis...
Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: retrospective cohort studyC van Walraven
Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa Hospital, Civic Campus, Ottawa, ON, Canada K1Y 4E9
BMJ 323:655-8. 2001..To determine the association between inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding...
Influence of house-staff experience on teaching-hospital mortality: The "July Phenomenon" revisitedCarl van Walraven
Faculty of Medicine, University of Ottawa, Ontario, Canada
J Hosp Med 6:389-94. 2011..Previous quantitative studies of new house-staff and increased mortality have been limited primarily by a focused patient population and the use of limited data to adjust for severity of patient illness...
Dissemination of discharge summaries. Not reaching follow-up physiciansCarl van Walraven
Can Fam Physician 48:737-42. 2002..To discover how often hospital discharge summaries were available to physicians seeing patients for follow-up visits after hospitalization...
The Procedural Index for Mortality Risk (PIMR): an index calculated using administrative data to quantify the independent influence of procedures on risk of hospital deathCarl van Walraven
Clinical Epidemiology Program, Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, K1Y 4E9, Canada
BMC Health Serv Res 11:258. 2011..This study derived and internally validated an index that can be calculated using administrative data to quantify the independent risk of hospital death after a procedure...
Changes in surrogate outcomes can be translated into clinical outcomes using a Monte Carlo modelCarl van Walraven
Ottawa Health Research Institute, University of Ottawa, Ontario, Canada
J Clin Epidemiol 62:1306-15. 2009..Formulae to do this are uncommon because they require primary data from multiple randomized trials that measure both the surrogate and clinical outcome...
Risk of subsequent thromboembolism for patients with pre-eclampsiaCarl van Walraven
Ottawa Health Research Institute, Ottawa, Canada K1Y 4E9
BMJ 326:791-2. 2003
The independent association of provider and information continuity on outcomes after hospital discharge: implications for hospitalistsCarl van Walraven
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Hosp Med 5:398-405. 2010..To determine how this influenced patient outcomes, we examined the independent association of several physician continuity and information continuity measures on death or urgent readmission after discharge from hospital...
Association of diagnostic radiation exposure and second abdominal-pelvic malignancies after testicular cancerCarl van Walraven
University of Ottawa, Ottawa, Ontario, Canada
J Clin Oncol 29:2883-8. 2011..Men recovering from low-grade testicular cancer frequently undergo serial abdominal-pelvic computerized tomography (CT) scanning to monitor for recurrent disease...
The influence of incidental abdominal aortic aneurysm monitoring on patient outcomesCarl van Walraven
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Vasc Surg 54:1290-1297.e2. 2011..These are common, and many undergo incomplete radiological monitoring. The association between monitoring completeness and population-based outcomes has not been studied...
Incidence of potentially avoidable urgent readmissions and their relation to all-cause urgent readmissionsCarl van Walraven
Faculty of Medicine, University of Ottawa, Ottawa, Ont
CMAJ 183:E1067-72. 2011..Urgent, unplanned hospital readmissions are increasingly being used to gauge the quality of care. We reviewed urgent readmissions to determine which were potentially avoidable and compared rates of all-cause and avoidable readmissions...
Risk of death or readmission is highest for Friday discharges from hospitalC van Walraven
, University of Ottawa, Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa, Ont
Hosp Q 5:25-6. 2002
The effect of a hepatitis serology testing algorithm on laboratory utilizationCarl van Walraven
Institute for Clinical Evaluative Sciences, Toronto, Canada
J Eval Clin Pract 8:327-32. 2002..Since over-utilization of hepatitis serological tests was suspected, a hepatitis serology testing algorithm was initiated in Ontario, Canada. This study determined the effects of this algorithm on utilization...
Administrative database research infrequently used validated diagnostic or procedural codesCarl van Walraven
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Clin Epidemiol 64:1054-9. 2011..Measure the proportion of ADR studies using diagnostic or procedural codes that measured or referenced code accuracy...
Risk of death or readmission among people discharged from hospital on FridaysCarl van Walraven
Clinical and Epidemiology Unit, Ottawa Health Research Institute, Ottawa Hospital, ON
CMAJ 166:1672-3. 2002
Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysisCarl van Walraven
Clinical Epidemiology Unit, Ottawa Health Research Institute, F 6, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, Ontario, Canada K1Y 4E9
JAMA 288:2441-8. 2002..Patients with nonvalvular atrial fibrillation (AF) have an increased risk of stroke and other vascular events...
Long-term outcomes and resource utilization of endovascular versus open repair of abdominal aortic aneurysms in OntarioPrasad Jetty
Division of Vascular Surgery, The Ottawa Hospital, University of Ottawa, Ontario, Canada
J Vasc Surg 51:577-83, 583.e1-3. 2010..Despite these data, the use of EVAR continues to increase in North America. Currently, there are very limited adjusted population-based data examining long-term outcomes and resource utilization...
An introduction to multilevel regression modelsP C Austin
Institute for Clinical Evaluative Sciences, G 160, 2075 Bayview Avenue, North York, ON, M4N 3M5
Can J Public Health 92:150-4. 2001..In comparing the resultant models, we see that false inferences can be drawn by ignoring the structure of the data...
Effect of population-based interventions on laboratory utilization: a time-series analysisC van Walraven
Clinical Epidemiology Unit, Ottawa Hospital, Ontario, Canada
JAMA 280:2028-33. 1998..Previous studies have identified methods of decreasing laboratory utilization. However, most were hospital-based, relatively small, single-centered, or of limited duration...
Clinical inertia in response to inadequate glycemic control: do specialists differ from primary care physicians?Baiju R Shah
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, ON, Canada M4N 3M5
Diabetes Care 28:600-6. 2005..quot; Because data suggest that specialist care results in better control than primary care, we evaluated whether specialists demonstrated less clinical inertia than primary care physicians...
What is necessary for high-quality discharge summaries?C van Walraven
Loeb Research Institute, University of Ottawa, Ottawa Hospital, Canada
Am J Med Qual 14:160-9. 1999..For this sample of physicians, summaries were of high quality when they were short, delivered quickly, and contained pertinent data that concentrated upon discharge information...
Dictated versus database-generated discharge summaries: a randomized clinical trialC van Walraven
Department of Medicine, Loeb Research Institute, University of Ottawa, Ont
CMAJ 160:319-26. 1999..They are most commonly generated by voice dictation and are often of poor quality. The objective of this study was to compare discharge summaries created by voice dictation with those generated from a clinical database...
Interactive voice response systems for improving delivery of ambulatory careNatalie Oake
Clinical Epidemiology Program, Ottawa Health Research Institute, 1053 Carling Ave, Ottawa, Ontario K1Y 4E9, Canada
Am J Manag Care 15:383-91. 2009..To comprehensively describe the populations, interventions, and outcomes of interactive voice response system (IVRS) clinical trials...
Maternal age and risk of stillbirth: a systematic reviewLing Huang
Health Surveillance and Epidemiology Division, Centre for Health Promotion, Public Health Agency of Canada, Ottawa, Ont
CMAJ 178:165-72. 2008..In this systematic review we explored whether older maternal age is associated with an increased risk of stillbirth...
Automated patient assessments after outpatient surgery using an interactive voice response systemAlan J Forster
Department of Medicine, University of Ottawa, Ontario, Canada
Am J Manag Care 14:429-36. 2008..To test the feasibility and utility of an interactive voice response system (IVRS) for monitoring patients after outpatient surgery...
Anticoagulation intensity and outcomes among patients prescribed oral anticoagulant therapy: a systematic review and meta-analysisNatalie Oake
Department of Medicine, University of Ottawa, and the Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ont
CMAJ 179:235-44. 2008..We sought to determine the association between anticoagulation intensity and the risk of hemorrhagic and thromboembolic events. We also sought to determine how under-or overanticoagulation would influence patient outcomes...
The impact of adverse events in the intensive care unit on hospital mortality and length of stayAlan J Forster
Department of Medicine, University of Ottawa, Ottawa, Canada
BMC Health Serv Res 8:259. 2008..We performed this study to measure the independent influence of intensive care unit (ICU) based AEs on in-hospital mortality and hospital length of stay...
Identifying patients with post-discharge care problems using an interactive voice response systemAlan J Forster
Department of Medicine, University of Ottawa, Ottawa, Canada
J Gen Intern Med 24:520-5. 2009..We designed an interactive voice response system (IVRS) with the intent of identifying patients who might be experiencing an AE following discharge or were at risk of developing one...
Combining ratings from multiple physician reviewers helped to overcome the uncertainty associated with adverse event classificationAlan J Forster
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Clin Epidemiol 60:892-901. 2007..We performed this study to quantify the misclassification rate obtained using current AE detection methods and to evaluate the effect of combining physician AE ratings...
Using an interactive voice response system to improve patient safety following hospital dischargeAlan J Forster
Department of Medicine, University of Ottawa, Ottawa, ON, Canada
J Eval Clin Pract 13:346-51. 2007..Patients often experience complications when transitioning from hospital to home. These complications are frequently related to poor monitoring. An interactive voice response system (IVRS) could improve post-discharge monitoring...
Effect of a nurse team coordinator on outcomes for hospitalized medicine patientsAlan J Forster
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Am J Med 118:1148-53. 2005..We do not know if adding a clinical nurse specialist (CNS) to physician teams in hospitals that already have discharge planning services makes a difference...
Adverse events detected by clinical surveillance on an obstetric serviceAlan J Forster
Ottawa Health Research Institute, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Obstet Gynecol 108:1073-83. 2006..We performed this study to estimate the rate of adverse events and potential adverse events-errors that have a high likelihood of causing patient harm-occurring during obstetric care...
Validation of a discharge summary term search method to detect adverse eventsAlan J Forster
FRCPC, C406 1053 Carling Avenue, Ottawa, ON, Canada K1Y 4E9
J Am Med Inform Assoc 12:200-6. 2005..We performed this study to validate a previously derived method of adverse event detection using term searching in physician-dictated discharge summaries...
Ottawa Hospital Patient Safety Study: incidence and timing of adverse events in patients admitted to a Canadian teaching hospitalAlan J Forster
Ottawa Health Research Institute, Ottawa, Ont
CMAJ 170:1235-40. 2004..We evaluated characteristics of adverse events affecting patients admitted to a Canadian teaching hospital, paying particular attention to timing...
Adverse events among medical patients after discharge from hospitalAlan J Forster
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
CMAJ 170:345-9. 2004..However, few data describe AEs after hospital discharge. We determined the incidence, severity, preventability and ameliorability of AEs in patients discharged from the general internal medicine service of a Canadian hospital...
Prevalence of information gaps in the emergency department and the effect on patient outcomesAndrew Stiell
Clinical Epidemiology Unit, Ottawa Health Research Institute, ON
CMAJ 169:1023-8. 2003..INTERPRETATION: Information gaps were present in almost one-third of the visits to our emergency department. They were more common in sicker patients and were independently associated with a prolonged stay in the emergency department...
The effect of hospital occupancy on emergency department length of stay and patient dispositionAlan J Forster
Departments of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 10:127-33. 2003..Emergency department (ED) overcrowding is a common problem. Despite a widespread belief that low hospital bed availability contributes to ED overcrowding, there are few data demonstrating this effect...
Did publication of a clinical practice guideline recommendation to screen for type 2 diabetes in women with gestational diabetes change practice?Heather D Clark
Ottawa Health Research Institute, Ontario, Canada
Diabetes Care 26:265-8. 2003..To determine whether women with previous gestational diabetes mellitus (GDM) were screened postpartum for type 2 diabetes according to the Canadian Diabetes Association (CDA) guidelines...
Improving patient safety: moving beyond the "hype" of medical errorsAlan J Forster
Department of Medicine and the Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont
CMAJ 173:893-4. 2005
Adverse events following an emergency department visitAlan J Forster
Ottawa Health Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada
Qual Saf Health Care 16:17-22. 2007..Many studies demonstrate a high rate of treatment-related adverse outcomes or adverse events. No studies have prospectively evaluated adverse events in patients discharged home from the emergency department (ED)...
Effect of discharge summary availability during post-discharge visits on hospital readmissionCarl van Walraven
Department of Medicine, University of Ottawa, Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa, ON, Canada
J Gen Intern Med 17:186-92. 2002..To determine if the delivery of hospital discharge summaries to follow-up physicians decreases the risk of hospital readmission...
The effect of hospitalization on oral anticoagulation control: a population-based studyCarl van Walraven
Department of Medicine, University of Ottawa, Clinical Epidemiology Program, Ottawa Health Research Institute, C405, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa ON, K1Y 4E9, Canada
Thromb Res 119:705-14. 2007..Previous studies examining OAC control may not generalize because the patient population was select or INR capture was incomplete...
Frequency of adverse events in patients with poor anticoagulation: a meta-analysisNatalie Oake
Department of Medicine, University of Ottawa, Ottawa, Ont
CMAJ 176:1589-94. 2007..To gauge the potential effect of improved anticoagulation control, we undertook to determine the proportion of anticoagulant-associated events that occur when INRs are outside the therapeutic range...
Validation of a clinical decision aid to discontinue in-hospital cardiac arrest resuscitationsC van Walraven
Department of Medicine, University of Ottawa, Ontario, Canada
JAMA 285:1602-6. 2001..In a previous study, we developed a clinical decision aid for identifying all patients undergoing resuscitation who survived to hospital discharge...
Do we know what inappropriate laboratory utilization is? A systematic review of laboratory clinical auditsC van Walraven
Institute for Clinical Evaluative Sciences, North York, Ontario, Canada
JAMA 280:550-8. 1998..Laboratory utilization has steadily increased, and some studies suggest inappropriate utilization. Therefore, we wished to assess studies that measure inappropriate laboratory use in light of methodological criteria...
Impact of immunosuppressive medication on the risk of renal allograft failure due to recurrent glomerulonephritisA V Mulay
Division of Nephrology, Kidney Research Centre, University of Ottawa, Ottawa, Ontario, Canada
Am J Transplant 9:804-11. 2009..The selection of immunosuppression for kidney transplant recipients should not be made with the goal of reducing graft failure due to recurrent glomerulonephritis...
Diabetic patients with prior specialist care have better glycaemic control than those with prior primary careBaiju R Shah
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
J Eval Clin Pract 11:568-75. 2005..To compare glycaemic control, as reflected in the A1c level, of diabetic patients with primary care vs. with specialist care...
Effect of an interactive voice response system on oral anticoagulant managementNatalie Oake
Clinical Epidemiology Program, Ottawa Health Research Institute, The Ottawa Hospital, Ottawa, ON K1Y 4E9
CMAJ 180:927-33. 2009..Monitoring oral anticoagulants is logistically challenging for both patients and medical staff. We evaluated the effect of adding an interactive voice response system to computerized decision support for oral anticoagulant management...
Quantifying the impact of survivor treatment bias in observational studiesPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Eval Clin Pract 12:601-12. 2006..Survivor treatment bias can arise when the time dependent nature of treatment exposure is ignored since patients who survived to receive treatment may be healthier than patients who died prior to receipt of treatment...
An hypothesis paper on practice environment and the provision of health care: could hospital occupancy rates effect quality?A Forster
Department of Medicine, University of Ottawa, ON, Canada
J Qual Clin Pract 20:69-74. 2000..We conclude that the relationship requires further exploration since revealing 'system' problems may compel clinicians to expose problems medical errors...
Mycophenolate mofetil dose reduction and the risk of acute rejection after renal transplantationGreg A Knoll
Division of Nephrology, Kidney Research Centre, and Department of Medicine, University of Ottawa, and Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa, Ontario, Canada
J Am Soc Nephrol 14:2381-6. 2003..Clinicians need to be aware of the rejection risk when the MMF dose is reduced and maintain close surveillance on such patients...
Coding diagnoses and procedures using a high-quality clinical database instead of a medical record reviewC van Walraven
Clinical Epidemiology Unit, Loeb Research Institute, Ottawa Hospital, Ottawa ON, Canada
J Eval Clin Pract 7:289-97. 2001..3 vs. C = 1.4; P = NS) were similar. Coding from a clinical database may circumvent the need for HRAs to review doctors' progress notes, while maintaining the quality of coding in the discharge abstract...
Outcomes of surveillance mammography after treatment of primary breast cancer: a population-based case seriesLawrence Paszat
Institute for Clinical Evaluative Sciences, Toronto, Canada
Breast Cancer Res Treat 114:169-78. 2009..To ascertain outcomes of surveillance mammography (SM) following treatment of early stage unilateral primary breast cancer (PBC) in a population based case series...
Restricted driver licensing for medical impairments: does it work?Shawn C Marshall
Department of Medicine, University of Ottawa, Ont
CMAJ 167:747-51. 2002....
Incidence and contributors to potential drug-drug interactions in hospitalized patientsLeanne Reimche
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Clin Pharmacol 51:1043-50. 2011..27 [2.23-2.30] for logarithm), and patient service (adjusted rate ratio, 1.49 [1.46-1.52] for surgical vs medical service). Potential DDIs were present during one fifth of hospitalization time...
How far is the sternal angle from the mid-right atrium?Ratika Seth
Department of Medicine, University of Ottawa, Ontario, Canada
J Gen Intern Med 17:852-6. 2002..When using the JVP to calculate the CVP, physicians need to consider specific patient factors and the patient's position...
When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increaseArsh K Jain
Division of Nephrology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
Kidney Int 76:318-23. 2009..However, it remains to be seen whether the routine reporting of eGFR results in improved treatment and outcomes for those with chronic kidney disease...
Effect of a controlled feedback intervention on laboratory test ordering by community physiciansPeter S Bunting
Gamma Dynacare Medical Laboratories, Brampton, Ontario, Canada
Clin Chem 50:321-6. 2004..We determined whether laboratory test utilization by community physicians could be reduced by a multifaceted program of education and feedback...
Utilization and outcomes of HbA1c testing: a population-based studyGraham Woodward
CMAJ 174:327-9. 2006
Effect of follow-up physician visits on emergency readmissionsCarl van Walraven
Am J Med 113:347; author reply 347. 2002
Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirinBrian F Gage
Division of General Medical Sciences, Washington University School of Medicine Campus Box 8005, 660 S Euclid Ave, St Louis, MO 63110, USA
Circulation 110:2287-92. 2004..This prospective cohort study tested the predictive accuracy of 5 stroke risk stratification schemes...
Additive role of plasma von Willebrand factor levels to clinical factors for risk stratification of patients with atrial fibrillationGregory Y H Lip
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, England
Stroke 37:2294-300. 2006..This study determined the additive role of plasma vWf levels to clinical factors for risk stratification in patients with AF...
Impact of specialist follow-up in outpatients with congestive heart failureJustin A Ezekowitz
Division of Cardiology, University of Alberta, Edmonton, Alta
CMAJ 172:189-94. 2005..Methods to improve timely and appropriate access to specialists and to improve collaborative care structures are needed...
Identifying individuals with a reduced GFR using ambulatory laboratory database surveillanceAmit X Garg
Division of Nephrology, University of Western Ontario, London Kidney Clinical Research Unit, Room A01, Westminster Tower, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada
J Am Soc Nephrol 16:1433-9. 2005..Whether such identification leads to improved health outcomes warrants further study...
Comparison of 12 risk stratification schemes to predict stroke in patients with nonvalvular atrial fibrillationRobert G Hart
Stroke 39:1901-10. 2008..Additional research to identify an optimum scheme for primary prevention and subsequent standardization of recommendations may lead to more uniform selection of patients for anticoagulant prophylaxsis...
Practice guidelines and practicing physicians-who's guiding whom?Carl van Walraven
Clin Chem 48:9-10. 2002
Bias in revascularization studyCarl van Walraven
CMAJ 176:1125; author reply 1125. 2007
