Research Topics
| Monica TaljaardSummaryAffiliation: Ottawa Health Research Institute Country: Canada Publications
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Detail Information
Publications
Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research studyMonica Taljaard
Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa Hospital, 1053 Carling Avenue, Civic Campus, C409, Ottawa, ON K1Y4E9, Canada
Trials 10:61. 2009....- Inadequate reporting of research ethics review and informed consent in cluster randomised trials: review of random sample of published trialsMonica Taljaard
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, Canada K1Y 4E9
BMJ 342:d2496. 2011.... - When is informed consent required in cluster randomized trials in health research?Andrew D McRae
Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON N6A5C1, Canada
Trials 12:202. 2011..Fifth, while health professionals may have a moral obligation to participate as subjects in research, this does not diminish the necessity of informed consent to study participation... - Who is the research subject in cluster randomized trials in health research?Andrew D McRae
Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada
Trials 12:183. 2011..Individuals who are indirectly affected by CRT study interventions, including patients of healthcare providers participating in knowledge translation CRTs, are not human research subjects unless at least one of these conditions is met... - Improved delivery of cardiovascular care (IDOCC) through outreach facilitation: study protocol and implementation details of a cluster randomized controlled trial in primary careClare Liddy
C, T, Lamont Primary Health Care Research Centre, Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
Implement Sci 6:110. 2011..abstract:.. - Comparison of primary care models in the prevention of cardiovascular disease - a cross sectional studyClare Liddy
C, T, Lamont Primary Health Care Research Centre, Elisabeth Bruyere Research Institute, 43 Bruyere St, Ottawa, Ontario, K1N 5C8, Canada
BMC Fam Pract 12:114. 2011..abstract:.. - Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): the first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarctionMonica Taljaard
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada
Am Heart J 159:354-60. 2010..However, a major limitation of autologous cell therapy is the deleterious influence of age and cardiac risk factors on progenitor cell activity... - Electronic search strategies to identify reports of cluster randomized trials in MEDLINE: low precision will improve with adherence to reporting standardsMonica Taljaard
Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa, Canada
BMC Med Res Methodol 10:15. 2010.... - Understanding the factors associated with differences in caesarean section rates at hospital level: the case of Latin AmericaMonica Taljaard
Ottawa Health Research Institute and University of Ottawa, Ottawa, Canada
Paediatr Perinat Epidemiol 23:574-81. 2009..The involvement of local quality control departments is an essential component in achieving success. Our results can be used to identify institutions that can be targets for further interventions to reduce CS rates... - Imputation strategies for missing continuous outcomes in cluster randomized trialsMonica Taljaard
Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa Hospital, 1053 Carling Avenue, Ottawa, Ontario, Canada
Biom J 50:329-45. 2008..Within-cluster multiple imputation is shown to be the least powerful among the procedures considered... - Intracluster correlation coefficients from the 2005 WHO Global Survey on Maternal and Perinatal Health: implications for implementation researchMonica Taljaard
Ottawa Health Research Institute and University of Ottawa, Ottawa, Ontario, Canada
Paediatr Perinat Epidemiol 22:117-25. 2008..We demonstrate that ICCs generally tend to increase with higher prevalences (close to 0.5). These results can help researchers calculate the required sample size for future research studies in maternal and perinatal health... - Accounting for expected attrition in the planning of community intervention trialsMonica Taljaard
Ottawa Health Research Institute, Clinical Epidemiology Program, The Ottawa Hospital, Ottawa, Canada
Stat Med 26:2615-28. 2007..To aid in the planning of future trials, we recommend that estimates for tau be reported in published community intervention trials... - Does clinical equipoise apply to cluster randomized trials in health research?Ariella Binik
Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
Trials 12:118. 2011..Finally, clinical equipoise provides research ethics committees with formal and procedural guidelines that form an important part of the assessment of the benefits and harms of CRTs in health research... - Ethical issues posed by cluster randomized trials in health researchCharles Weijer
Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
Trials 12:100. 2011..Our hope is that these papers will serve as the basis for the creation of international ethical guidelines for the design and conduct of cluster randomized trials... - International survey of emergency physicians' awareness and use of the Canadian Cervical-Spine Rule and the Canadian Computed Tomography Head RuleDebra Eagles
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 15:1256-61. 2008..The objectives were to determine: 1) physician awareness and use of these rules in Australasia, Canada, the United Kingdom, and the United States and 2) physician characteristics associated with awareness and use... - Emergency physicians' management of transient ischemic attack and desired sensitivity of a clinical decision rule for stroke in three countriesJeffrey J Perry
Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Canada
CJEM 13:19-27. 2011.... - Performer fatigue and CPR quality comparing 30:2 to 15:2 compression to ventilation ratios in older bystanders: A randomized crossover trialChristian Vaillancourt
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Resuscitation 82:51-6. 2011..We sought to compare bystander fatigue and CPR quality after 5min of CPR using the 30:2 vs. the 15:2 chest compression:ventilation ratios in a population of older participants... - The independent association of provider and information continuity on outcomes after hospital discharge: implications for hospitalistsCarl van Walraven
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Hosp Med 5:398-405. 2010..To determine how this influenced patient outcomes, we examined the independent association of several physician continuity and information continuity measures on death or urgent readmission after discharge from hospital... - A prospective cohort study found that provider and information continuity was low after patient discharge from hospitalCarl van Walraven
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
J Clin Epidemiol 63:1000-10. 2010..This study is a detailed examination of continuity of care in patients discharged from hospital that simultaneously measured separate components of continuity over time or determined the factors with which they are associated... - Changes in surrogate outcomes can be translated into clinical outcomes using a Monte Carlo modelCarl van Walraven
Ottawa Health Research Institute, University of Ottawa, Ontario, Canada
J Clin Epidemiol 62:1306-15. 2009..Formulae to do this are uncommon because they require primary data from multiple randomized trials that measure both the surrogate and clinical outcome... - Measuring acceptability of clinical decision rules: validation of the Ottawa acceptability of decision rules instrument (OADRI) in four countriesJamie C Brehaut
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, ON, Canada
Med Decis Making 30:398-408. 2010..No existing instrument measures the acceptability of a rule. The current study validated such an instrument... - Information exchange among physicians caring for the same patient in the communityCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, ASB1 003, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ONK1Y4E9
CMAJ 179:1013-8. 2008..This study determined the probability that patient information from previous visits with other physicians was available for a current physician visit... - National survey of Canadian neurologists' current practice for transient ischemic attack and the need for a clinical decision ruleJeffrey J Perry
Department of Emergency Medicine, Clinical Epidemiology Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada
Stroke 41:987-91. 2010..This national survey examined Canadian neurologists' current practice for managing TIA, the need for a clinical decision rule to identify high-risk patients, and the required sensitivity of such a rule... - The effect of hospital-acquired infection with Clostridium difficile on length of stay in hospitalAlan J Forster
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont
CMAJ 184:37-42. 2012..We determined the independent impact of hospital-acquired infection with C. difficile on length of stay in hospital... - Does adding risk-trends to survival models improve in-hospital mortality predictions? A cohort studyJenna Wong
Clinical Epidemiology Program, Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, K1Y 4E9, Canada
BMC Health Serv Res 11:171. 2011..In this study, we used a unique approach to measure trends in patient hospital death risk and determined whether the incorporation of these trend measures into a survival model improved the accuracy of its risk predictions... - Audit and feedback using the brief Decision Support Analysis Tool (DSAT-10) to evaluate nurse-standardized patient encountersDawn Stacey
School of Nursing, University of Ottawa, Ottawa, Ont, Canada
Patient Educ Couns 73:519-25. 2008..To evaluate the brief Decision Support Analysis Tool (DSAT-10) for auditing the quality of nurse-standardized patient encounters, structuring feedback for nurses, and testing instrument reliability... - Intravenous lidocaine does not reduce length of hospital stay following abdominal hysterectomyGregory L Bryson
Department of Anesthesiology, The Ottawa Hospital Civic Campus, Ottawa, ON, Canada
Can J Anaesth 57:759-66. 2010..The purpose of this trial was to determine if intravenous lidocaine limited to the intraoperative period reduces length of hospital stay and improves functional recovery following abdominal hysterectomy... - A pilot study to assess the feasibility of a multicenter cluster randomized trial for the management of asymptomatic persons with a thrombophiliaPhilip S Wells
University of Ottawa, ON, Canada
J Genet Couns 18:475-82. 2009..The question of the best educational approach in these patients remains unanswered. The value of testing and following asymptomatic carriers of probands with VTE and thrombophilia remains unknown... - Fluid resuscitation in the management of early septic shock (FINESS): a randomized controlled feasibility trialLauralyn A McIntyre
University of Ottawa Centre for Transfusion and Critical Care Research, Ottawa Hospital, Ottawa, Ontario, Canada
Can J Anaesth 55:819-26. 2008..This randomized controlled trial determined the feasibility of conducting a large trial testing resuscitation with pentastarch vs normal saline in early septic shock, powered for a difference in mortality... - The merits of breaking the matches: a cautionary taleAllan Donner
Department of Epidemiology and Biostatistics, Schulich School of Medicine, University of Western Ontario, London, Canada
Stat Med 26:2036-51. 2007....