Research Topics
| I G StiellSummaryAffiliation: Ottawa Health Research Institute Country: Canada Publications
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Publications
What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation?Ian G Stiell
Department of Emergency Medicine and Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Crit Care Med 40:1192-8. 2012..We sought to study patterns of cardiopulmonary resuscitation compression depth and their associations with patient outcomes in out-of-hospital cardiac arrest cases treated by the 2005 guideline standards...
The Chest Pain Choice trial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency departmentMeghan A Pierce
Knowledge and Encounter Research Unit, Mayo Clinic, Rochester, Minnesota, USA
Trials 11:57. 2010..The aims of this study are (1) to develop a decision aid (CHEST PAIN CHOICE) that communicates the short-term risk of ACS and (2) to evaluate the impact of the decision aid on patient participation in decision-making and resource use...
Evaluation of the safety of C-spine clearance by paramedics: design and methodologyChristian Vaillancourt
Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital Civic Campus, 1053 Carling Avenue, Room F 658, Ottawa, ON, K1Y 4E9, Canada
BMC Emerg Med 11:1. 2011..The prolonged immobilization is often unnecessary and adds to the burden of already overtaxed emergency medical services systems and crowded emergency departments...
A survey of factors associated with the successful recognition of agonal breathing and cardiac arrest by 9-1-1 call takers: design and methodologyChristian Vaillancourt
Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital Civic Campus Floor 6, Box 685, 1053 Carling Avenue, Ottawa Ontario, K1Y 4E9, Canada
BMC Emerg Med 9:14. 2009..Improving 9-1-1 call takers' ability to recognize agonal breathing as a sign of cardiac arrest could result in improved bystander cardiopulmonary resuscitation and survival rates for out-of-hospital cardiac arrest victims...
A study to derive a clinical decision rule for triage of emergency department patients with chest pain: design and methodologyErik P Hess
Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
BMC Emerg Med 8:3. 2008..Currently no methodologically robust clinical decision rule identifies patients safe for early discharge...
A survey of attitudes and factors associated with successful cardiopulmonary resuscitation (CPR) knowledge transfer in an older population most likely to witness cardiac arrest: design and methodologyChristian Vaillancourt
Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, Canada
BMC Emerg Med 8:13. 2008..However, interest in CPR training appears to decrease with advancing age. Behaviour surrounding CPR training and performance has never been studied using well validated behavioural theories...
An evaluation of 9-1-1 calls to assess the effectiveness of dispatch-assisted cardiopulmonary resuscitation (CPR) instructions: design and methodologyChristian Vaillancourt
Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, Canada
BMC Emerg Med 8:12. 2008..Dispatch-assisted CPR instructions are recommended by the International Guidelines on Emergency Cardiovascular Care, but their ability to improve cardiac arrest survival remains unclear...
BIPHASIC Trial: a randomized comparison of fixed lower versus escalating higher energy levels for defibrillation in out-of-hospital cardiac arrestIan G Stiell
Department of Emergency Medicine, Ottawa Health Research Institute, University of Ottawa, Ontario, Canada, K1Y 4E9
Circulation 115:1511-7. 2007..The present study compared fixed lower- and escalating higher-energy regimens for out-of-hospital cardiac arrest...
Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trialIan G Stiell
Department of Emergency Medicine, University of Ottawa, Canada
BMJ 339:b4146. 2009..To evaluate the effectiveness of an active strategy to implement the validated Canadian C-Spine Rule into multiple emergency departments...
Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 2: rationale and methodology for "Analyze Later vs. Analyze Early" protocolIan G Stiell
Ottawa, Ontario, Canada
Resuscitation 78:186-95. 2008....
Health-related quality of life is better for cardiac arrest survivors who received citizen cardiopulmonary resuscitationIan Stiell
Clinical Epidemiology Unit, Office F657, Ottawa Health Research Institute, 1053 Carling Ave, Ottawa, Ontario K1Y 4E9, Canada
Circulation 108:1939-44. 2003..This study evaluated the prehospital factors associated with better health-related quality of life for survivors of out-of-hospital cardiac arrest...
Advanced cardiac life support in out-of-hospital cardiac arrestIan G Stiell
Department of Emergency Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa Ont, Canada
N Engl J Med 351:647-56. 2004..The Ontario Prehospital Advanced Life Support (OPALS) Study tested the incremental effect on the rate of survival after out-of-hospital cardiac arrest of adding a program of advanced life support to a program of rapid defibrillation...
Comparison of the Cerebral Performance Category score and the Health Utilities Index for survivors of cardiac arrestIan G Stiell
Department of Emergency Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 53:241-248. 2009..We evaluate the comparability of results from the Cerebral Performance Category scale versus those of the validated but more complex Health Utilities Index scale for health-related quality of life...
Emergency department use of intravenous procainamide for patients with acute atrial fibrillation or flutterIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ontario, Canada
Acad Emerg Med 14:1158-64. 2007..The objective of this study was to examine the efficacy and safety of intravenous (IV) procainamide for acute atrial fibrillation or flutter...
Implementation of clinical decision rules in the emergency departmentIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 14:955-9. 2007..Well-developed and validated CDRs can be successfully implemented into practice, efficiently standardizing ED care. However, further research is needed to identify barriers to implementation in order to achieve improved uptake in the ED...
The Canadian C-spine rule for radiography in alert and stable trauma patientsI G Stiell
Clinical Epidemiology Unit, F6, Ottawa Health Research Institute, 1053 Carling Ave, Ottawa, Ontario, Canada K1Y 4E9
JAMA 286:1841-8. 2001..High levels of variation and inefficiency exist in current clinical practice regarding use of cervical spine (C-spine) radiography in alert and stable trauma patients...
Association of the Ottawa Aggressive Protocol with rapid discharge of emergency department patients with recent-onset atrial fibrillation or flutterIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ont
CJEM 12:181-91. 2010..We sought to examine the effectiveness and safety of the Ottawa Aggressive Protocol to perform rapid cardioversion and discharge patients with these arrhythmias...
A prospective cluster-randomized trial to implement the Canadian CT Head Rule in emergency departmentsIan G Stiell
Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont
CMAJ 182:1527-32. 2010..We sought to evaluate the effectiveness of implementing this validated decision rule at multiple emergency departments...
The Canadian CT Head Rule for patients with minor head injuryI G Stiell
Divisions of Emergency Medicine, University of British Columbia, Vancouver, Canada
Lancet 357:1391-6. 2001..There is much controversy about the use of computed tomography (CT) for patients with minor head injury. We aimed to develop a highly sensitive clinical decision rule for use of CT in patients with minor head injuries...
Vernakalant hydrochloride: A novel atrial-selective agent for the cardioversion of recent-onset atrial fibrillation in the emergency departmentIan G Stiell
Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Canada
Acad Emerg Med 17:1175-82. 2010..This study sought to evaluate the efficacy and safety of vernakalant for patients with recent-onset AF...
Vasopressin versus epinephrine for inhospital cardiac arrest: a randomised controlled trialI G Stiell
Division of Emergency Medicine, University of Ottawa, Ottawa, Canada
Lancet 358:105-9. 2001..Our aim was to compare the effectiveness and safety of these drugs for the treatment of in-patient cardiac arrest...
Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departmentsIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 57:13-21. 2011..We seek to evaluate variation in ED management practices for recent-onset atrial fibrillation and flutter patients at multiple Canadian sites and to determine whether hospital site was an independent predictor of attempted cardioversion...
Canadian Cardiovascular Society atrial fibrillation guidelines 2010: management of recent-onset atrial fibrillation and flutter in the emergency departmentIan G Stiell
Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Can J Cardiol 27:38-46. 2011..Adequate follow-up of patients with recent-onset AF/AFL is recommended to identify structural heart disease and evaluate the need for long-term antithrombotic or antiarrhythmic therapy...
Multicentre prospective validation of use of the Canadian C-Spine Rule by triage nurses in the emergency departmentIan G Stiell
Department of Emergency Medicine, University of Ottawa, and the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Department of Nursing, Ottawa Hospital, Ottawa, Ontario
CMAJ 182:1173-9. 2010..We believe that nurses in the emergency department could use this rule to clinically clear the cervical spine. We prospectively evaluated the accuracy, reliability and acceptability of the Canadian C-Spine Rule when used by nurses...
Early versus later rhythm analysis in patients with out-of-hospital cardiac arrestIan G Stiell
Department of Emergency Medicine and Ottawa Hospital Research Institute, University of Ottawa, Ottawa
N Engl J Med 365:787-97. 2011..We compared the strategy of a brief period of CPR with early analysis of rhythm with the strategy of a longer period of CPR with delayed analysis of rhythm...
A multicenter, open-label study of vernakalant for the conversion of atrial fibrillation to sinus rhythmIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
Am Heart J 159:1095-101. 2010..nct00281554)...
The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation)I G Stiell
Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, Ontario, Canada K1Y 4E9
Ann Emerg Med 38:160-9. 2001..The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med. August 2001;38:160-169.]..
CPR-only survivors of out-of-hospital cardiac arrest: implications for out-of-hospital care and cardiac arrest research methodologyV J De Maio
Ottawa Hospital Ontario Health Research Institute, Ottawa, Ontario, Canada
Ann Emerg Med 37:602-8. 2001..The objective of this study was to identify out-of-hospital cardiac arrest survivors resuscitated without defibrillation or advanced cardiac life support...
Association of drug therapy with survival in cardiac arrest: limited role of advanced cardiac life support drugsI G Stiell
University of Ottawa Faculty of Medicine, Ontario, Canada
Acad Emerg Med 2:264-73. 1995..To generate hypotheses regarding the association of standard Advanced Cardiac Life Support (ACLS) drugs with human cardiac arrest survival...
Canadian CT head rule study for patients with minor head injury: methodology for phase II (validation and economic analysis)I G Stiell
Ottawa Health Research Institute, Ottawa, Ontario, Canada
Ann Emerg Med 38:317-22. 2001..This will determine the clinical utility of the rule and is essential if such a rule is to be widely adopted into clinical practice...
Emergency physicians' attitudes toward and use of clinical decision rules for radiographyI D Graham
Ottawa Civic Hospital, Ontario, Canada
Acad Emerg Med 5:134-40. 1998....
What is the quality of life for survivors of cardiac arrest? A prospective studyG Nichol
Clinical Epidemiology Unit, Loeb Research Institute, University of Ottawa, Ontario, Canada
Acad Emerg Med 6:95-102. 1999..To evaluate the quality of life of survivors of in-hospital and out-of-hospital cardiac arrest, and to correlate quality of life with clinically important parameters...
Cardioversion of paroxysmal atrial fibrillation in the emergency departmentJ A Michael
Division of Emergency Medicine, University of Ottawa, University of Ottawa Emergency Medicine Residency Programme, Ottawa, Ontario, Canada
Ann Emerg Med 33:379-87. 1999..The objective of this study was to review the success and safety of ED cardioversion and discharge of patients with acute atrial fibrillation...
A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrestG Nichol
Clinical Epidemiology Unit, Loeb Health Research Institute, Division of General Internal Medicine, Ottawa, Ontario, Canada
Ann Emerg Med 34:517-25. 1999....
Socioeconomic status influences bystander CPR and survival rates for out-of-hospital cardiac arrest victimsC Vaillancourt
Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Resuscitation 79:417-23. 2008..We used residential property values as a proxy for socioeconomic status to determine if there was an association with: (1) bystander CPR rates and (2) survival to hospital discharge for out-of-hospital cardiac arrest...
An economic analysis of the Ottawa knee ruleG Nichol
Clinical Epidemiology Unit, Loeb Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 34:438-47. 1999..To conduct an economic analysis of the implementation of the Ottawa Knee Rule...
Awareness and use of the Ottawa ankle and knee rules in 5 countries: can publication alone be enough to change practice?I D Graham
Department of Medicine, Faculty of Medicine, University of Ottawa, Canada
Ann Emerg Med 37:259-66. 2001..We evaluate the international diffusion of the Ottawa Ankle and Knee Rules and determine emergency physicians' attitudes toward clinical decision rules in general...
Feasibility of a structured 3-minute walk test as a clinical decision tool for patients presenting to the emergency department with acute dyspnoeaA M Pan
Clinical Epidemiology Unit, Ottawa Health Research Institute, The Ottawa Hospital, Ottawa, Canada
Emerg Med J 26:278-82. 2009..It also aimed to gather evidence and directions for the design of a multicentre study to derive clinical guidelines...
Adverse events following an emergency department visitAlan J Forster
Ottawa Health Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada
Qual Saf Health Care 16:17-22. 2007..Many studies demonstrate a high rate of treatment-related adverse outcomes or adverse events. No studies have prospectively evaluated adverse events in patients discharged home from the emergency department (ED)...
The interobserver reliability of pretest probability assessment in patients with suspected pulmonary embolismMarc A Rodger
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Thromb Res 116:101-7. 2005..We sought to determine (for patients with suspected PE) the interobserver reliability of pretest probability assessment (by overall impression (gestalt) versus an explicit clinical model)...
The effect of hospital occupancy on emergency department length of stay and patient dispositionAlan J Forster
Departments of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 10:127-33. 2003..Emergency department (ED) overcrowding is a common problem. Despite a widespread belief that low hospital bed availability contributes to ED overcrowding, there are few data demonstrating this effect...
Comparison of termination-of-resuscitation guidelines for basic life support: defibrillator providers in out-of-hospital cardiac arrestMarcus E H Ong
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 47:337-43. 2006..We compare the performance of 3 termination-of-resuscitation guidelines for basic life support-defibrillator (BLS) providers when applied to cardiac arrest patients in the Ontario Prehospital Advanced Life Support study...
Adverse events among patients registered in high-acuity areas of the emergency department: a prospective cohort studyLisa Anne Calder
Department of Emergency Medicine, University of Ottawa, Ontario, Canada
CJEM 12:421-30. 2010..We performed this study to describe the types and risk of adverse events in high-acuity areas of the emergency department (ED)...
Adverse outcomes and opioid analgesic administration in acute abdominal painJ S Lee
Clinical Epidemiology Unit, Ottawa Hospital Loeb Health Research Institute, Ottawa, Ontario
Acad Emerg Med 7:980-7. 2000..To the authors' knowledge, no outcome-based, randomized clinical trial of the safety of opioid analgesics in acute abdominal pain exists...
The bedside investigation of pulmonary embolism diagnosis study: a double-blind randomized controlled trial comparing combinations of 3 bedside tests vs ventilation-perfusion scan for the initial investigation of suspected pulmonary embolismMarc A Rodger
University of Ottawa, Ottawa Health Research Institute, and Department of Medicine, Ottawa Hospital, Ottawa, Ontario, Canada
Arch Intern Med 166:181-7. 2006..CONCLUSION: Excluding PE with at least 2 negative results on 3 bedside tests safely eliminates the need for diagnostic imaging in 34% of patients with suspected PE...
Etiology of pediatric out-of-hospital cardiac arrest by coroner's diagnosisMarcus E H Ong
Department of Emergency Medicine, University of Ottawa, Canada
Resuscitation 68:335-42. 2006..To determine etiology of pediatric OHCA in a population-based sample from autopsy and coroner's diagnosis...
Stratified, urgent care for transient ischemic attack results in low stroke ratesJason Wasserman
Division of Neurology, Ottawa Hospital, Ottawa, Ontario, Canada
Stroke 41:2601-5. 2010..We hypothesized that an ABCD2-based ED triaging tool for TIA with outpatient management would be associated with lower 90-day stroke rate than that predicted by ABCD2...
In-hospital mortality in 13,263 survivors of out-of-hospital cardiac arrest in CanadaCalum Redpath
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Am Heart J 159:577-583.e1. 2010..The secondary objective was to examine predictors of in-hospital survival in these patients...
Comparing pre-hospital clinical diagnosis of pediatric out-of-hospital cardiac arrest with etiology by coroner's diagnosisMarcus E H Ong
Department of Emergency Medicine, University of Ottawa, Canada
Resuscitation 72:26-34. 2007..We aimed to compare the etiology of pediatric OHCA by pre-hospital clinical diagnosis with etiology by coroner's diagnosis and autopsy...
Measurement of driving patterns of older adults using data logging devices with and without global positioning system capabilityShawn C Marshall
Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
Traffic Inj Prev 8:260-6. 2007..Electronic data logging devices may offer a reliable, alternative method of measuring driving exposure, and global positioning system (GPS) technology may be able to provide further information about driving patterns...
Diagnostic performance of venous lactate on arrival at the emergency department for myocardial infarctionMathieu Gatien
Emergency Department, The Ottawa Hospital, General Campus, 501 Smyth Road, Ottawa, Ontario, Canada
Acad Emerg Med 12:106-13. 2005..To determine the sensitivity of the venous lactate level at presentation for acute myocardial infarction (AMI) in emergency department (ED) patients with chest pain...
Clinically important change in the visual analog scale after adequate pain controlJacques Simon Lee
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Acad Emerg Med 10:1128-30. 2003..To define the minimum clinically important difference (MCID) for the visual analog scale (VAS) of pain severity by measuring the change in VAS associated with adequate pain control...
The Resuscitation Outcomes Consortium Epistry-Trauma: design, development, and implementation of a North American epidemiologic prehospital trauma registryCraig D Newgard
Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, OR 97239 3098, United States
Resuscitation 78:170-8. 2008..This data registry samples patients from 264 EMS agencies transporting to 287 acute care hospitals in both the United States and Canada...
Prevalence of information gaps in the emergency department and the effect on patient outcomesAndrew Stiell
Clinical Epidemiology Unit, Ottawa Health Research Institute, ON
CMAJ 169:1023-8. 2003..INTERPRETATION: Information gaps were present in almost one-third of the visits to our emergency department. They were more common in sicker patients and were independently associated with a prolonged stay in the emergency department...
Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 1: rationale and methodology for the impedance threshold device (ITD) protocolTom P Aufderheide
Milwaukee, WI, USA
Resuscitation 78:179-85. 2008..Secondary aims are to compare functional status and depression at discharge and at 3 and 6 months post-discharge in survivors...
The Canadian C-spine rule versus the NEXUS low-risk criteria in patients with traumaIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ont, Canada
N Engl J Med 349:2510-8. 2003..CONCLUSIONS: For alert patients with trauma who are in stable condition, the CCR is superior to the NLC with respect to sensitivity and specificity for cervical-spine injury, and its use would result in reduced rates of radiography...
The OPALS Major Trauma Study: impact of advanced life-support on survival and morbidityIan G Stiell
The Department of Emergency Medicine, University of Ottawa, and the Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ont
CMAJ 178:1141-52. 2008..To date, the benefit of prehospital advanced life-support programs on trauma-related mortality and morbidity has not been established..
Information exchange among physicians caring for the same patient in the communityCarl van Walraven
Clinical Epidemiology Program, Ottawa Health Research Institute, ASB1 003, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ONK1Y4E9
CMAJ 179:1013-8. 2008..This study determined the probability that patient information from previous visits with other physicians was available for a current physician visit...
The Canadian C-spine rule performs better than unstructured physician judgmentGlen Bandiera
Division of Emergency Medicine, University of Toronto, Toronto, Ontario, Canada
Ann Emerg Med 42:395-402. 2003..The Canadian C-Spine rule was better at detecting clinically important injuries with a sensitivity of 100%. Prospective validation has recently been completed and should permit widespread use of the Canadian C-Spine rule...
Optimal defibrillation response intervals for maximum out-of-hospital cardiac arrest survival ratesValerie J De Maio
Ottawa Health Research Institute, Ottawa, Ontario, Canada
Ann Emerg Med 42:242-50. 2003..The objective of this study was to analyze survival as a function of time to test the evidence for this standard...
Outpatient oral prednisone after emergency treatment of chronic obstructive pulmonary diseaseShawn D Aaron
Department of Medicine, University of Ottawa, Ottawa, Ont, Canada
N Engl J Med 348:2618-25. 2003..In this randomized, double-blind, placebo-controlled trial, we studied the effectiveness of prednisone in reducing the risk of relapse after outpatient exacerbations of chronic obstructive pulmonary disease (COPD)...
A clinical decision rule for cranial computed tomography in minor pediatric head traumaShireen M Atabaki
Division of Emergency Medicine, Children s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC 20010 2970, USA
Arch Pediatr Adolesc Med 162:439-45. 2008....
Effect of arthroscopic débridement for osteoarthritis of the knee on health-related quality of lifeGeoffrey F Dervin
Department of Surgery, University of Ottawa, Ottawa Hospital, Ontario, Canada
J Bone Joint Surg Am 85:10-9. 2003....
Emergency Medical Services Outcomes Project (EMSOP) IV: pain measurement in out-of-hospital outcomes researchRonald F Maio
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Ann Emerg Med 40:172-9. 2002..Future research in out-of-hospital care should be conducted to determine the utility and feasibility of these measures, as well as the effectiveness of interventions for pain relief...
Emergency Medical Services Outcomes Project III (EMSOP III): the role of risk adjustment in out-of-hospital outcomes researchHerbert G Garrison
Department of Emergency Medicine, The Brody School of Medicine at East Carolina University, Greenville, NC 27858 4354, USA
Ann Emerg Med 40:79-88. 2002..We recommend that these potential core RAMs be systematically evaluated for use in risk adjustment of out-of-hospital patient groups that might be used for outcomes research..
Comparison of the Canadian CT Head Rule and the New Orleans Criteria in patients with minor head injuryIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
JAMA 294:1511-8. 2005....
Vernakalant hydrochloride for rapid conversion of atrial fibrillation: a phase 3, randomized, placebo-controlled trialDenis Roy
Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
Circulation 117:1518-25. 2008..The present study assessed the efficacy and safety of vernakalant hydrochloride (RSD1235), a novel compound, for the conversion of atrial fibrillation (AF)...
International survey of emergency physicians' priorities for clinical decision rulesDebra Eagles
Department of Emergency Medicine, Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Acad Emerg Med 15:177-82. 2008..This study examined the clinical priorities of emergency physicians (EPs) working in Australasia, Canada, the United Kingdom, and the United States for the development of future CDRs...
Nontraumatic out-of-hospital hypotension predicts inhospital mortalityAlan E Jones
Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC, USA
Ann Emerg Med 43:106-13. 2004..Future research should focus on ED clinical protocols to ensure appropriate resuscitation and investigation of etiology of out-of-hospital hypotension...
Clinical features of head injury patients presenting with a Glasgow Coma Scale score of 15 and who require neurosurgical interventionCatherine M Clement
Clinical Epidemiology Program, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 48:245-51. 2006..Our objectives are to determine the accuracy of the Canadian CT Head Rule (CCHR) in this important subset, the prevalence of patients requiring urgent intervention, and their clinical course and possible warning signs...
Clinical sensibility and barriers to knowledge translationJamie C Brehaut
Ann Intern Med 145:77-8. 2006
Cardiac arrest care and emergency medical services in CanadaChristian Vaillancourt
Ottawa Health Research Institute, Department of Emergency Medicine, University of Ottawa, Ontario
Can J Cardiol 20:1081-90. 2004..Heart disease is the primary cause of mortality in Canada and survival to hospital discharge from out-of-hospital cardiac arrest is low...
Will a new clinical decision rule be widely used? The case of the Canadian C-spine ruleJamie C Brehaut
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Acad Emerg Med 13:413-20. 2006..widespread use of a new, relatively complex CDR an attainable goal? 2) How do physician perceptions of the new CDR compare with those of a widely used rule? 3) To what extent do physician subgroups differ in likelihood to use a new rule?..
Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledgeAaron J Donoghue
Division of Critical Care Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Ann Emerg Med 46:512-22. 2005..We systematically summarize pediatric out-of-hospital cardiac arrest epidemiology and assess knowledge of effects of specific out-of-hospital interventions...
The San Francisco Syncope Rule vs physician judgment and decision makingJames V Quinn
Division of Emergency Medicine, Stanford University, Palo Alto, CA 94304, USA
Am J Emerg Med 23:782-6. 2005..To compare a clinical decision rule (San Francisco Syncope Rule [SFSR]) and physician decision making when predicting serious outcomes in patients with syncope...
Clinical decision rules "in the real world": how a widely disseminated rule is used in everyday practiceJamie C Brehaut
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Acad Emerg Med 12:948-56. 2005..Widespread, appropriate use of clinical decision rules would result in many benefits for health care. While it is known that clinicians report using these rules, little is known about how the rules are actually used in everyday practice...
Attitudes and judgment of emergency physicians in the management of patients with acute headacheJeffrey J Perry
Department of Emergency Medicine, University of Ottawa, Ontario, Canada
Acad Emerg Med 12:33-7. 2005....
A randomized, controlled trial of RSD1235, a novel anti-arrhythmic agent, in the treatment of recent onset atrial fibrillationDenis Roy
Montreal Heart Institute, University of Montreal, 5000 Belanger Street, Montreal, Quebec, Canada H1T 1C8
J Am Coll Cardiol 44:2355-61. 2004..The purpose of this study was to determine the efficacy and safety of intravenous RSD1235 in terminating recent onset atrial fibrillation (AF)...
Should spectrophotometry be used to identify xanthochromia in the cerebrospinal fluid of alert patients suspected of having subarachnoid hemorrhage?Jeffrey J Perry
Department of Emergency Medicine, University of Ottawa, ON, Canada
Stroke 37:2467-72. 2006..Authorities advocate spectrophotometry to measure xanthochromia, but most North American hospitals use visual inspection. We studied the diagnostic accuracy of spectrophotometry for SAH, and its potential impact on current practice...
Impact of clinical decision rules on clinical care of traumatic injuries to the foot and ankle, knee, cervical spine, and headJeffrey J Perry
Clinical Epidemiology Program, The Ottawa Hospital, University of Ottawa, Canada
Injury 37:1157-65. 2006..There has been much interest in the development of clinical decision rules to help guide the investigations of these patients in a standardised and cost-effective manner...
Comparison of early mortality of paramedic-diagnosed ST-segment elevation myocardial infarction with immediate transport to a designated primary percutaneous coronary intervention center to that of similar patients transported to the nearest hospitalMichel R Le May
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Am J Cardiol 98:1329-33. 2006..In conclusion, paramedic-referred primary PCI is a safe and feasible strategy for treating STEMI that is associated with rapid and effective reperfusion and very low in-hospital mortality...
Understanding and improving low bystander CPR rates: a systematic review of the literatureChristian Vaillancourt
Ottawa Health Research Institute, Ottawa, Ontario, Canada
CJEM 10:51-65. 2008..Cardiopulmonary resuscitation (CPR) is a crucial yet weak link in the chain of survival for out-of-hospital cardiac arrest. We sought to understand the determinants of bystander CPR and the factors associated with successful training...
Is the combination of negative computed tomography result and negative lumbar puncture result sufficient to rule out subarachnoid hemorrhage?Jeffrey J Perry
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 51:707-13. 2008..Our objective is to determine the sensitivity of a negative CT result combined with a negative lumbar puncture result to exclude subarachnoid hemorrhage...
Derivation of the San Francisco Syncope Rule to predict patients with short-term serious outcomesJames V Quinn
Division of Emergency Medicine, University of California San Francisco, San Francisco, CA 94304, USA
Ann Emerg Med 43:224-32. 2004..We derive a decision rule that would predict patients at risk for short-term serious outcomes and help guide admission decisions...
Retrospective application of the NEXUS low-risk criteria for cervical spine radiography in Canadian emergency departmentsGarth Dickinson
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 43:507-14. 2004..The NEXUS low-risk criteria should be further explicitly and prospectively evaluated for accuracy and reliability before widespread clinical use outside of the United States...
Evaluating the effectiveness of dispatch-assisted cardiopulmonary resuscitation instructionsChristian Vaillancourt
Ottawa Health Research Institute, Ottawa, Ontario, Canada
Acad Emerg Med 14:877-83. 2007....
Print format and sender recognition were related to survey completion rateJamie C Brehaut
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa Hospital, Civic Campus, ASB 2 004, Box 693, 1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada
J Clin Epidemiol 59:635-41. 2006..To assess whether print format (single-sided vs. double) and sender recognition (known vs. unknown) affect response and completion rates among physician survey respondents...
Initial emergency department trauma scores from the OPALS study: the case for the motor score in blunt traumaMajid A Al-Salamah
Department of Emergency Medicine, Department of Epidemiology and Community MedicineUniversity of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 11:834-42. 2004..CONCLUSIONS: The initial emergency department motor score showed the highest predictive validity among all of the other components. These results suggest its validity for blunt trauma triage when compared with the GCS or RTS...
Management and outcomes of pediatric patients transported by emergency medical services in a Canadian prehospital systemJulie Richard
Faculty of Medicine, University of Ottawa, Ottawa, ON
CJEM 8:6-12. 2006..Very few children receive prehospital airway management, ventilation or IV medications; consequently EMS personnel have little opportunity to maintain these pediatric skills in the field...
What are the etiology and epidemiology of out-of-hospital pediatric cardiopulmonary arrest in Ontario, Canada?Richard Bradley Gerein
Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
Acad Emerg Med 13:653-8. 2006..Pediatric cardiopulmonary arrest (CPA) outside of the hospital has a very high mortality rate...
CT scanning for minor head injuryIan G Stiell
JAMA 295:498. 2006
Advanced life support for out-of-hospital respiratory distressIan G Stiell
Department of Emergency Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa, ON, Canada
N Engl J Med 356:2156-64. 2007..Respiratory distress is a common symptom of patients transported to hospitals by emergency medical services (EMS) personnel. The benefit of advanced life support for such patients has not been established...
Establishing the scope and methodological approach to out-of-hospital outcomes and effectiveness researchSamuel M Keim
Arizona Emergency Medicine Research Center, Department of Emergency Medicine, University of Arizona, 1501 North Campbell, Tucson, AZ 85724, USA
Acad Emerg Med 11:1067-73. 2004..Illustrations of the specific applications of outcomes research and implications to existing methodologies are given, as well as suggestions for improved interdisciplinary research...
A clinical decision rule to identify which chest pain patients can safely be removed from cardiac monitoring in the emergency departmentMathieu Gatien
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
Ann Emerg Med 50:136-43. 2007....
Risk adjustment and outcome measures for out-of-hospital respiratory distressSamuel M Keim
Arizona Emergency Medicine Research Center, Department of Emergency Medicine, University of Arizona, 1501 North Campbell, Tucson, AZ 85724, USA
Acad Emerg Med 11:1074-81. 2004..Furthermore, using mortality as an outcome measure is also recommended. Future research is needed to alleviate the paucity of validated tools for out-of-hospital outcomes research...
Research Grants
- OPTIMAL PREHOSPITAL CARE OF CHILDHOOD CARDIAC ARRESTIan Stiell; Fiscal Year: 2004..The PIs propose to conduct a large feasibility review in five urban areas and to conduct four study planning workshops. ..
- PROPOSAL TO CREATE A CANADIAN COLLABORATIVE RCCIan Stiell; Fiscal Year: 2007..This trial will compare prehospital mandatory Rapid Sequence Intubation followed by controlled ventilation to Standard Airway management in trauma patients with head injury and decreased level of consciousness. ..
