K F T Copeland

Summary

Affiliation: Ottawa Health Research Institute
Country: Canada

Publications

  1. ncbi The role of CD8+ T cell soluble factors in human immunodeficiency virus infection
    K F T Copeland
    Centre for Molecular Medicine, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    Curr Med Chem 9:1781-90. 2002
  2. ncbi Identification of mutations in proviral long terminal repeats of HIV type 1-infected subjects naive to drug therapy
    Karen F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada K1H 8L6
    AIDS Res Hum Retroviruses 20:1019-21. 2004
  3. ncbi Modulation of HIV-1 transcription by cytokines and chemokines
    K F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Mini Rev Med Chem 5:1093-101. 2005
  4. ncbi Inhibition of HIV-1 entry into cells
    Karen F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa ON K1H 8L6, Canada
    Recent Pat Antiinfect Drug Discov 1:107-12. 2006
  5. ncbi Properties of HTLV-I transformed CD8+ T-cells in response to HIV-1 infection
    N Gulzar
    National HIV and Retrovirology Laboratories, Public Health Agency of Canada, Ottawa, Canada
    Virology 406:302-11. 2010
  6. ncbi Production of CD8+ T cell nonlytic suppressive factors by CD28, CD38, and HLA-DR subpopulations
    Janina Q Jiang
    Center for Molecular Medicine, Ottawa Health Research Institute, Ottawa, Ontario K1H 8L6, Canada
    AIDS Res Hum Retroviruses 19:497-502. 2003
  7. ncbi CD8+ T-cells: function and response to HIV infection
    Naveed Gulzar
    Ottawa Health Research Institute, Ottawa, Ontario, Canada
    Curr HIV Res 2:23-37. 2004
  8. ncbi Effects of highly active antiretroviral therapy and immune recovery on CD8+ T-cell-mediated inhibition of HIV-1 transcription
    Greg Beaudoin
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada
    J Acquir Immune Defic Syndr 43:393-400. 2006

Collaborators

  • John E Kim
  • N Gulzar
  • Greg Beaudoin
  • Naveed Gulzar
  • Janina Q Jiang
  • A Shroff
  • D Klonowska
  • B Buberoglu
  • Bilge Diker
  • Jonathan B Angel
  • Kenneth L Rosenthal
  • Andrew D Badley
  • Nanci C Hawley-Foss
  • Sowmya Balasubramanian

Detail Information

Publications8

  1. ncbi The role of CD8+ T cell soluble factors in human immunodeficiency virus infection
    K F T Copeland
    Centre for Molecular Medicine, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    Curr Med Chem 9:1781-90. 2002
    ..An understanding of the mechanisms involved in the CD8-mediated control of transcription may identify other factors with potential value in the treatment of HIV infection...
  2. ncbi Identification of mutations in proviral long terminal repeats of HIV type 1-infected subjects naive to drug therapy
    Karen F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada K1H 8L6
    AIDS Res Hum Retroviruses 20:1019-21. 2004
    ..A higher overall frequency of mutations within the LTR occurred within NFAT-1 and Sp-1 sequences. Importantly, a novel 16-bp deletion was found in the distal NFAT-1 site...
  3. ncbi Modulation of HIV-1 transcription by cytokines and chemokines
    K F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Mini Rev Med Chem 5:1093-101. 2005
    ..This review will examine the complexities of the positive and negative control of HIV transcription by cytokines and chemokines...
  4. ncbi Inhibition of HIV-1 entry into cells
    Karen F T Copeland
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa ON K1H 8L6, Canada
    Recent Pat Antiinfect Drug Discov 1:107-12. 2006
    ..In this review, the entry blocking drugs that have recently been patented, their mode of action in inhibiting HIV-1 and their efficacy in clinical trials will be discussed...
  5. ncbi Properties of HTLV-I transformed CD8+ T-cells in response to HIV-1 infection
    N Gulzar
    National HIV and Retrovirology Laboratories, Public Health Agency of Canada, Ottawa, Canada
    Virology 406:302-11. 2010
    ..These transformed cells provide an important tool in the study of CD8(+) T-cells and may provide important insights into the mechanism(s) behind HIV-1 induced CD8(+) T-cell dysfunction...
  6. ncbi Production of CD8+ T cell nonlytic suppressive factors by CD28, CD38, and HLA-DR subpopulations
    Janina Q Jiang
    Center for Molecular Medicine, Ottawa Health Research Institute, Ottawa, Ontario K1H 8L6, Canada
    AIDS Res Hum Retroviruses 19:497-502. 2003
    ..These findings shed light on CD8(+) T cell noncytotoxic antiviral factor production during HIV infection...
  7. ncbi CD8+ T-cells: function and response to HIV infection
    Naveed Gulzar
    Ottawa Health Research Institute, Ottawa, Ontario, Canada
    Curr HIV Res 2:23-37. 2004
    ..The end result is the aberration of CD8+ T-cell function...
  8. ncbi Effects of highly active antiretroviral therapy and immune recovery on CD8+ T-cell-mediated inhibition of HIV-1 transcription
    Greg Beaudoin
    Molecular Medicine Program, Ottawa Health Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada
    J Acquir Immune Defic Syndr 43:393-400. 2006
    ..Furthermore, we have distinguished between CD8 T-cell-mediated suppression of HIV-1 replication and gene transcription...