Abedelnasser Abulrob

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. ncbi Nanoscale imaging of epidermal growth factor receptor clustering: effects of inhibitors
    Abedelnasser Abulrob
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R5, Canada
    J Biol Chem 285:3145-56. 2010
  2. ncbi In vivo optical imaging of ischemic blood-brain barrier disruption
    Abedelnasser Abulrob
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Methods Mol Biol 763:423-39. 2011
  3. ncbi In vivo time domain optical imaging of renal ischemia-reperfusion injury: discrimination based on fluorescence lifetime
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON
    Mol Imaging 6:304-14. 2007
  4. ncbi Dynamic analysis of the blood-brain barrier disruption in experimental stroke using time domain in vivo fluorescence imaging
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON
    Mol Imaging 7:248-62. 2008
  5. ncbi Evaluation of brain tumor vessels specific contrast agents for glioblastoma imaging
    Boguslaw Tomanek
    Institute for Biodiagnostics West, National Research Council of Canada, Calgary, Alberta, Canada
    Neuro Oncol 14:53-63. 2012
  6. ncbi Small unilamellar vesicles: a platform technology for molecular imaging of brain tumors
    Umar Iqbal
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Nanotechnology 22:195102. 2011
  7. ncbi In vitro and in vivo methods for assessing FcRn-mediated reverse transcytosis across the blood-brain barrier
    Nadia Caram-Salas
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Methods Mol Biol 763:383-401. 2011
  8. ncbi The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    J Neurochem 95:1201-14. 2005
  9. ncbi Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, 1200 Montreal Road, Ottawa, Ontario, K!A 0R6, Canada
    J Neurochem 92:1477-86. 2005
  10. ncbi Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada K1A0R6
    Oncogene 23:6967-79. 2004

Collaborators

Detail Information

Publications11

  1. ncbi Nanoscale imaging of epidermal growth factor receptor clustering: effects of inhibitors
    Abedelnasser Abulrob
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R5, Canada
    J Biol Chem 285:3145-56. 2010
    ..Changes in receptor clustering provide one mechanism for regulating EGFR signaling and are relevant to the design of strategies for therapeutic interventions based on modulating EGFR signaling...
  2. ncbi In vivo optical imaging of ischemic blood-brain barrier disruption
    Abedelnasser Abulrob
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Methods Mol Biol 763:423-39. 2011
    ..5 was 40% greater. The volume differential between areas of BBB disruption for small and large-size molecules could be useful for determining the size of peri-infarct tissues (penumbra) that can respond to neuroprotective therapies...
  3. ncbi In vivo time domain optical imaging of renal ischemia-reperfusion injury: discrimination based on fluorescence lifetime
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON
    Mol Imaging 6:304-14. 2007
    ..The study suggests that fluorescence lifetime analysis of endogenous tissue fluorophores could be used to discriminate ischemic or necrotic tissues by noninvasive in vivo or ex vivo organ imaging...
  4. ncbi Dynamic analysis of the blood-brain barrier disruption in experimental stroke using time domain in vivo fluorescence imaging
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON
    Mol Imaging 7:248-62. 2008
    ....
  5. ncbi Evaluation of brain tumor vessels specific contrast agents for glioblastoma imaging
    Boguslaw Tomanek
    Institute for Biodiagnostics West, National Research Council of Canada, Calgary, Alberta, Canada
    Neuro Oncol 14:53-63. 2012
    ..T(2)-weighted MRI and near infrared imaging are able to detect the targeting effects in brain tumors...
  6. ncbi Small unilamellar vesicles: a platform technology for molecular imaging of brain tumors
    Umar Iqbal
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Nanotechnology 22:195102. 2011
    ..The unique features of these targeted sULVs make them promising molecular MRI contrast agents...
  7. ncbi In vitro and in vivo methods for assessing FcRn-mediated reverse transcytosis across the blood-brain barrier
    Nadia Caram-Salas
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Methods Mol Biol 763:383-401. 2011
    ..In vivo models use Prospective optical imaging to measure the clearance rate of intracerebrally injected FcRn-transported molecules tagged with near-infrared fluorescent probes...
  8. ncbi The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    J Neurochem 95:1201-14. 2005
    ..This putative receptor may be a new target for developing brain-targeting drug delivery vectors...
  9. ncbi Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, 1200 Montreal Road, Ottawa, Ontario, K!A 0R6, Canada
    J Neurochem 92:1477-86. 2005
    ....
  10. ncbi Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae
    Abedelnasser Abulrob
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada K1A0R6
    Oncogene 23:6967-79. 2004
    ..The evidence suggests that the phosphorylation-regulated sequestration of EGFR in caveolae may be involved in arresting constitutive or ligand-induced signaling through EGFR responsible for glial cell transformation...
  11. ncbi Integrated platform for brain imaging and drug delivery across the blood-brain barrier
    Umar Iqbal
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    Methods Mol Biol 686:465-81. 2011
    ..This method allows for a prospective, noninvasive estimation of drug delivery, accumulation, and elimination from the brain...