Research Topics
Genomes and GenesSpecies | Keith JarviSummaryAffiliation: Mount Sinai Hospital Country: Canada Publications
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Detail Information
Publications
Characterization of the seminal plasma proteome in men with prostatitis by mass spectrometryDaniel Kagedan
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada
Clin Proteomics 9:2. 2012..abstract:..- Mini-incision microsurgical vasectomy reversal using no-scalpel vasectomy principles and instrumentsKeith Jarvi
Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Urology 72:913-5. 2008..To reduce the morbidity of a vasectomy reversal, we have developed techniques to perform a microsurgical vasectomy reversal through a mini-incision in the scrotum... - The genetics you never knew: a genetics primerKeith Jarvi
Division of Urology, Department of Surgery, Murray Koffler Urologic Wellness Centre, Mount Sinai Hospital, University of Toronto, Joseph and Wolf Lebovic Building, 60 Murray Street, 6th Floor, Toronto, Ontario, M5T 3L9
Urol Clin North Am 35:243-56, ix. 2008..In this article we review the structure and function of the genes, how genes are packaged, gene replication, gene mutations, and the different modes of inheritance... - Daily vardenafil for 6 months has no detrimental effects on semen characteristics or reproductive hormones in men with normal baseline levelsKeith Jarvi
Mount Sinai Hospital, Toronto, Ontario, Canada
J Urol 179:1060-5. 2008.... - Microsurgical varicocelectomy for infertile men with oligospermia: differential effect of bilateral and unilateral varicocele on pregnancy outcomesAbdulaziz Baazeem
Division of Urology, Department of Surgery, McGill University, Montreal, Quebec, Canada
BJU Int 104:524-8. 2009.... - Potential adverse effect of sperm DNA damage on embryo quality after ICSIArmand Zini
Division of Urology, Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada
Hum Reprod 20:3476-80. 2005..The objective of this study was to examine further the relationship between sperm DNA denaturation (DD) and reproductive outcomes after ICSI... - Natural history of varicocele management in the era of intracytoplasmic sperm injectionArmand Zini
Department of Surgery, Division of Urology, McGill University, Montreal, Quebec, Canada
Fertil Steril 90:2251-6. 2008..To evaluate the outcomes of infertile couples with varicocele... - Cause-specific treatment in patients with high sperm DNA damage resulted in significant DNA improvementSergey I Moskovtsev
Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Syst Biol Reprod Med 55:109-15. 2009..7%+/-12.8 vs. 28.4%+/-9.5, p < .03). The majority of the patients 13/14 (93%) with bacteriospermia had improvement in sperm DFI results after antibiotic treatment (50.4%+/-19.1 vs. 38.6%+/-18.7, p < .001)... - Frequency and severity of sperm DNA damage in patients with confirmed cases of male infertility of different aetiologiesSergey I Moskovtsev
Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Reprod Biomed Online 20:759-63. 2010..The data support the importance of proper physical and laboratory investigations of the fertility status in men to correctly diagnose and treat male infertility... - Testicular spermatozoa have statistically significantly lower DNA damage compared with ejaculated spermatozoa in patients with unsuccessful oral antioxidant treatmentSergey I Moskovtsev
Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Fertil Steril 93:1142-6. 2010..To compare DNA damage in ejaculated and testicular spermatozoa in patients with previously unsuccessful oral antioxidant treatment... - Microsurgical varicocelectomy for infertile couples with advanced female age: natural history in the era of ARTBen Bowles
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Androl 25:939-43. 2004..Overall, these data suggest that varicocelectomy is an acceptable option for couples with advanced female age, but other female factors must be considered in the decision-making process... - Beneficial effect of microsurgical varicocelectomy is superior for men with bilateral versus unilateral repairJamie Libman
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Urol 176:2602-5; discussion 2605. 2006..Little is known about the differential effect of bilateral, compared to unilateral varicocelectomy, on male fertility potential... - High levels of sperm DNA denaturation as the sole semen abnormality in a patient after chemotherapy for testis cancerLeslie Deane
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Androl 25:23-4. 2004 - Varicocelectomy may benefit men with a sertoli cell-only pattern on microsurgical testicular sperm extraction: a case reportJason Lee
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Ontario, Canada
Urology 71:1226.e17-8. 2008..This case demonstrates that patients with a failed TESE may gain some benefit from a varicocelectomy and that this procedure may be offered as an alternative to donor insemination or adoption... - Varicocelectomy for infertile couples with advanced paternal ageArmand Zini
Division of Urology, Department of Surgery, McGill University, Montreal, Quebec, Canada
Urology 72:109-13. 2008..To evaluate the reproductive outcomes of infertile couples with a clinical varicocele and advanced paternal age... - The effect of radiation on semen quality and fertility in men treated with brachytherapy for early stage prostate cancerDilpreet K Singh
Division of Urology, Princess Margaret Hospital and Mount Sinai Hospital, Toronto, Ontario, Canada
J Urol 187:987-9. 2012..We determined the effects of prostatic brachytherapy on semen parameters and sperm DNA integrity, and the potential impact on fertility... - Does the gonadotropin-releasing hormone stimulation test predict clinical outcomes after microsurgical varicocelectomy?Ben Bowles
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Urology 63:1143-7. 2004..The study was the largest of its type and sufficiently powered to validate these findings. The results indicate that the bolus GnRH stimulation test is of no clinical value in the treatment of infertile men with varicoceles... - Comparison of sperm quality and DNA integrity in mouse sperm exposed to various cooling velocities and osmotic stressCengiz Yildiz
Physiology and Experimental Medicine Research Program, The Hospital for Sick Children, Toronto, Ontario, Canada
Theriogenology 74:1420-30. 2010..Additionally, osmotically-driven volume changes in mouse sperm increased DNA fragmentation, with susceptibility affected by background strain... - Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assayAndrei P Drabovich
Samuel Lunenfeld Research Institute, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Mol Cell Proteomics 10:M110.004127. 2011.... - The utility and cost of Chlamydia trachomatis and Neisseria gonorrhoeae screening of a male infertility populationTrustin Domes
Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 97:299-305. 2012..To determine the utility and cost of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) screening in infertile males... - Vasectomy reversal provides long-term pain relief for men with the post-vasectomy pain syndromeDavid Horovitz
Division of Urology, Mount Sinai Hospital, Toronto, Ontario, Canada
J Urol 187:613-7. 2012..However, there is a paucity of data in the literature defining its therapeutic efficacy. In this study we better define the role and effect of vasectomy reversal in the treatment of men with the post-vasectomy pain syndrome... - Mini-incision vasectomy reversal using no-scalpel vasectomy principles: efficacy and postoperative pain compared with traditional approaches to vasectomy reversalEthan D Grober
Division of Urology, Mount Sinai and Women s College Hospital, University of Toronto, Toronto, Ontario, Canada
Urology 77:602-6. 2011..To evaluate the efficacy and postoperative morbidity of a mini-incision vasectomy reversal (MIVR) using no-scalpel vasectomy principles compared with traditional incisional approaches to vasectomy reversal (VR)... - Small incidentally discovered testicular masses in infertile men--is active surveillance the new standard of care?Paul J Toren
Division of Urology, Department of Surgery, Mount Sinai Hospital and New Women s College Hospital, University of Toronto, Toronto, Ontario, Canada
J Urol 183:1373-7. 2010..Although these neoplasms are classically treated with surgical excision, ultrasound surveillance has been proposed as an alternative to surgery... - Use of the aromatase inhibitor letrozole to treat male infertilityGeneviève Patry
Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 92:829.e1-2. 2009..Report the case of induction of spermatogenesis with the aromatase inhibitor letrozole... - The role of cross-sectional imaging in male infertility: a pictorial reviewKartik S Jhaveri
Abdominal Imaging, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada
Can Assoc Radiol J 61:144-55. 2010.... - Use of alternative and hormonal therapies in male infertilityArmand Zini
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Urology 63:141-3. 2004..It is important to inquire about the use of these therapies because some of these treatments may be toxic to the gonads... - Identification of potentially damaging amino acid substitutions leading to human male infertilityAnastasia Kuzmin
Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada
Biol Reprod 81:319-26. 2009..All of the novel mutations were in a heterozygous configuration, suggesting that they may be de novo mutations with dominant negative properties... - Varicoceles: the diagnostic dilemmaJason Lee
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Canada
J Androl 29:143-6. 2008..The dilemma is that there are no widely accepted or used criteria to diagnose a varicocele based on imaging. This paper reviews the different imaging techniques used and the accuracy of each in diagnosing a varicocele... - Time for improvement in semen parameters after varicocelectomyAyman Al Bakri
Division of Urology, Mount Sinai Hospital, University of Toronto, Toronto, Canada
J Urol 187:227-31. 2012..Therefore, in this study we identified the changes with time in semen parameters after varicocelectomy... - CUA Guideline: The workup of azoospermic malesKeith Jarvi
Keith Jarvi, Director, Murray Koffler Urologic Wellness Centre, Head of Urology, Mount Sinai Hospital, Professor of Surgery, University of Toronto, Director, Male Infertility Program, Toronto, ON
Can Urol Assoc J 4:163-7. 2010..The members represent different practices in different communities... - Postmortem sperm retrieval: the Canadian perspectiveBryce Weber
Divisions of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Androl 30:407-9. 2009.... - Epididymal P34H protein deficiency in men evaluated for infertilitySergey I Moskovtsev
Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Fertil Steril 88:1455-7. 2007..Our results suggest that a significant proportion of men investigated for male infertility may be epididymal protein P34H deficient... - Should all urologists performing vasectomy reversals be able to perform vasoepididymostomies if required?Ashis Chawla
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Urol 172:1048-50. 2004..We recommend that all surgeons offering vasectomy reversals be able to offer VE if required based on intraoperative findings to serve the patient adequately as well as his partner and their future fertility... - Molecular alterations during progression of prostate cancer to androgen independencePunit Saraon
Samuel Lunenfeld Research Institute and Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada
Clin Chem 57:1366-75. 2011..However, over time, most tumors become androgen independent and no longer respond to hormonal therapies. Several mechanisms have been implicated in the progression of prostate cancer to androgen independence... - Prevalence of abnormal sperm DNA denaturation in fertile and infertile menArmand Zini
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Urology 60:1069-72. 2002..Additional studies are needed to support the notion that isolated abnormalities of sperm DNA integrity may represent a new diagnosis for men with unexplained infertility... - Renal colic and torsion: case report and reviewStephen Lazarou
Division of Urology, University of Toronto, Toronto, Ontario, Canada
Can J Urol 9:1702-3. 2002..Acute ureteric colic and acute scrotum are among the most commonly seen urological emergencies. We present a case in which a male patient presented with simultaneous right flank pain and ipsilateral scrotal pain... - Characterization of organic cation/carnitine transporter family in human spermWanli Xuan
Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, Ont, M5G 1X8, Toronto, Canada
Biochem Biophys Res Commun 306:121-8. 2003..7+/-20.5 pmol/min/mg protein; n=18). Identification of individuals with defective sperm carnitine transport may provide potentially treatable etiologies of male infertility, responsive to L-carnitine supplementation... - Propecia-induced spermatogenic failure: a report of two casesKimberly E Liu
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Toronto, Reproductive Biology Unit, Mount Sinai Hospital, Toronto, ON, Canada
Fertil Steril 90:849.e17-9. 2008..To describe the results of two cases of azoospermia and severe oligospermia in men during and after cessation of finasteride 1 mg... - Testicular block using intra-testicular lidocaine: a new anaesthetic technique for percutaneous testis biopsyKhaled Kamal
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Can J Urol 9:1568-70; discussion 1571. 2002..Only 1/45 men had a post-procedure testicular hematoma (this resolved in 4 weeks). CONCLUSIONS: Intra-testicular lidocaine appears to be a simple, rapid and safe method to provide anaesthesia for a percutaneous testis biopsy...