Research Topics
| Gord BlackhouseSummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Canadian cost-utility analysis of initiation and maintenance treatment with anti-TNF-? drugs for refractory Crohn's diseaseGord Blackhouse
Programs for Assessment of Technology in Health Research Institute, McMaster University, Hamilton, ON, Canada
J Crohns Colitis 6:77-85. 2012..However, these medications are quite expensive. The objective of this study is to evaluate the cost-utility of two anti-TNF-? drugs (infliximab, adalimumab) for refractory CD...- A note on the estimation of confidence intervals for cost-effectiveness when costs and effects are censoredGordon Blackhouse
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Med Decis Making 22:173-7. 2002..The authors address the joint problem of estimating ICER precision in the presence of censoring... - Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in CanadaGord Blackhouse
PATH Research Institute, McMaster University, Hamilton, Ontario, Canada
Cost Eff Resour Alloc 8:14. 2010..The objective of the paper is to evaluate, from a Canadian perspective, the cost-effectiveness of IVIG compared to corticosteroid treatment of CIDP... - A cost-effectiveness model comparing endovascular repair to open surgical repair of abdominal aortic aneurysms in CanadaGord Blackhouse
Program for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Ontario, Canada
Value Health 12:245-52. 2009..EVAR is less invasive than OR, and therefore may have less surgical risk than OR. However, the graft used for EVAR is much more expensive then the graft used for OR... - Effects of study design and trends for EVAR versus OSRRobert Hopkins
Program for the Assessment of Technology in Health PATH Research Institute, Department of Clinical Epidemiology and Biostatistics, London Health Sciences Center, London, Ontario, Canada
Vasc Health Risk Manag 4:1011-22. 2008..Finally, we investigate trends over time in EVAR versus OSR outcomes... - Illustrating economic evaluation of diagnostic technologies: comparing Helicobacter pylori screening strategies in prevention of gastric cancer in CanadaFeng Xie
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
J Am Coll Radiol 6:317-23. 2009..The aim of this paper is to present an economic evaluation of diagnostic technologies using Helicobacter pylori screening strategies for the prevention of gastric cancer as an illustration... - Health technology assessment and primary data collection for reducing uncertainty in decision makingRon Goeree
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
J Am Coll Radiol 6:332-42. 2009..An illustrative example is used to show how the Ontario HTA process works and the role value of information analyses plays in addressing decision uncertainty, determining research feasibility, and determining study data collection needs... - Results of a model analysis to estimate cost utility and value of information for intravenous immunoglobulin in Canadian adults with chronic immune thrombocytopenic purpuraFeng Xie
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Clin Ther 31:1082-91; discussion 1066-8. 2009..The aim of this work was to estimate the cost-effectiveness of intravenous immunoglobulin (IVIg) compared with oral prednisone as a treatment for Canadian adults with persistent chronic immune thrombocytopenic purpura (ITP)... - Cost-effectiveness analysis of elective endovascular repair compared with open surgical repair of abdominal aortic aneurysms for patients at a high surgical risk: A 1-year patient-level analysis conducted in Ontario, CanadaJean Eric Tarride
Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare, Hamilton, Ontario, Canada
J Vasc Surg 48:779-87. 2008..The objective of this study was to estimate the cost-effectiveness and cost-utility of elective endovascular aneurysm repair (EVAR) compared with open surgical repair (OSR) in patients at a high risk of surgical complications... - Universal or targeted screening for fetal alcohol exposure: a cost-effectiveness analysisRobert B Hopkins
Program for Assessment of Technology in Health, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, 25 Main Street West, Suite 2000, Hamilton, Ontario, L8P 2A1, Canada
J Stud Alcohol Drugs 69:510-9. 2008..In this article, we compared the costs of testing meconium for alcohol exposure in newborns with the lifetime benefits of early detection and intervention... - Patient outcomes after anti TNF-alpha drugs for Crohn's diseaseNazila Assasi
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare, Hamilton, 25 Main Street West, Suite 2000 ON, Canada
Expert Rev Pharmacoecon Outcomes Res 10:163-75. 2010..The review further considers the evidence for the harms and benefits associated with switching from one anti-TNF-alpha agent to another and strategies to optimize the timing of therapy... - Conditionally funded field evaluations and practical trial design within a health technology assessment frameworkJames M Bowen
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
J Am Coll Radiol 6:324-31. 2009.... - In search of the evidentiary foundation of published Canadian economic evaluations (2001-06)Jean Eric Tarride
Department of Clinical Epidemiology and Biostatistics, McMaster University, Programs for Assessment of Technology in Health PATH Research Institute, 25 Main Street West, Suite 2000, Hamilton, Ontario L8P 1H1, Canada
Int J Technol Assess Health Care 25:214-21. 2009.... - Economic evaluations conducted by Canadian health technology assessment agencies: where do we stand?Jean Eric Tarride
Department of Clinical Epidemiology and Biostatistics, McMaster University St Joseph s Healthcare Hamilton, 25 Main Street West, Hamilton, Ontario, Canada
Int J Technol Assess Health Care 24:437-44. 2008..To examine the production of Health Technology Assessments (HTAs) with economic evaluations (EEs) conducted by Canadian HTA agencies... - A review of methods used in long-term cost-effectiveness models of diabetes mellitus treatmentJean Eric Tarride
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, 25 Main Street West, Hamilton, Ontario, Canada
Pharmacoeconomics 28:255-77. 2010..Future research should continue to compare economic models for diabetes treatment in terms of clinical outcomes, costs and QALYs when applicable... - Cost-effectiveness of reducing wait times for cataract surgery in OntarioRobert B Hopkins
Department of Clinical Epidemiology and Biostatistics, McMaster University, and the Programs for Assessment of Technology in Health Research Institute, St Joseph s Hospital, Hamilton, ON, Canada
Can J Ophthalmol 43:213-7. 2008..The objective of the study was to use queuing models to determine the cost-effectiveness of reducing, to target levels, wait times for cataract surgery at the provincial level within 1 to 10 years by increasing treatment volumes... - Impact of the 1997 Canadian guidelines on the conduct of Canadian-based economic evaluations in the published literatureMorgan E Lim
Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, ON, Canada
Value Health 13:328-34. 2010..To assess the impact of the 1997 Canadian guidelines on the methods and presentation of economic evaluations conducted from a Canadian perspective in the published literature... - Economic evaluation of drug-eluting stents compared to bare metal stents using a large prospective study in OntarioRon Goeree
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Int J Technol Assess Health Care 25:196-207. 2009.... - Using health technology assessment to support evidence-based decision-making in Canada: an academic perspectiveFeng Xie
Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
Expert Rev Pharmacoecon Outcomes Res 11:513-21. 2011..Some issues and challenges are also highlighted that will hopefully stimulate a broader discussion among HTA stakeholders to move HTA forward... - Should endovascular repair be reimbursed for low risk abdominal aortic aneurysm patients? Evidence from ontario, CanadaJean Eric Tarride
Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton and Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada L8P 1H1
Int J Vasc Med 2011:308685. 2011..Conclusions. Despite a similar clinical effectiveness, these results suggest that, at the current price, EVAR is more expensive than open repair for low risk patients... - Transferability of economic evaluations: approaches and factors to consider when using results from one geographic area for anotherRon Goeree
St Joseph s Hospital, Hamilton, ON, Canada
Curr Med Res Opin 23:671-82. 2007..However, inappropriate transferability of economic data can provide misleading results and lead to an inefficient use of scarce health care resources... - Approaches for economic evaluations of health care technologiesJean Eric Tarride
Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
J Am Coll Radiol 6:307-16. 2009..This review improves upon the previous educational papers published in radiologic journals, as it covers recent methodologic advances regarding the treatment of uncertainty... - Triple therapy for the management of COPD: a reviewKathryn Gaebel
Programs for Assessment of Technology in Health PATH Research Institute, McMaster University, Hamilton, Ontario L8P 1H1
COPD 8:206-43. 2011..There is insufficient evidence to determine if triple therapy is superior to dual bronchodilator therapy... - Cost-effectiveness analysis of Helicobacter pylori screening in prevention of gastric cancer in ChineseFeng Xie
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Int J Technol Assess Health Care 24:87-95. 2008..The aim of this study was to evaluate the costs and effectiveness associated with no screening, Helicobacter pylori serology screening, and the 13C-urea breath test (UBT) for gastric cancer in the Chinese population... - Cost-utility analysis of infliximab and adalimumab for refractory ulcerative colitisFeng Xie
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Cost Eff Resour Alloc 7:20. 2009..Future research could be aimed at the long-term clinical benefits of these drugs, especially adalimumab for patients intolerant or unresponsive to infliximab treatment... - A view from the bridge: agreement between the SF-6D utility algorithm and the Health Utilities IndexBernie J O'Brien
Department of Clinical Epidemiology and Biostatistics, McMaster University, Canada
Health Econ 12:975-81. 2003..The Health Utilities Index, mark 3 (HUI3) is a valid and reliable multi-attribute health utility scale that is widely used. We assessed within-subject agreement between SF-6D utilities and those from HUI3... - Cost-effectiveness of rhythm versus rate control in atrial fibrillationDeborah A Marshall
Center for Evaluation of Medicine, McMaster University and St Joseph s Hospital, Hamilton, Ontario, Canada
Ann Intern Med 141:653-61. 2004..Consequently, economic factors often play a role in guiding treatment selection... - Oseltamivir for treatment of influenza in healthy adults: pooled trial evidence and cost-effectiveness model for CanadaBernie J O'Brien
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Value Health 6:116-25. 2003..Oseltamivir (Tamiflu) is a neuraminidase inhibitor-a new class of antiviral treatment for influenza where efficacy and safety has been established but cost-effectiveness is unknown... - Cost-effectiveness and cost-utility of long-term management strategies for heartburnRon Goeree
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 1G6, Canada
Value Health 5:312-28. 2002..To compare the expected costs and outcomes of seven alternative long-term primary care strategies for the management of patients with moderate-to-severe heartburn over a 1-year period... - General population versus disease-specific event rate and cost estimates: potential bias for economic appraisalsRon Goeree
Programs for the Assessment of Technology in Health Research Institute, 25 Main St W, Suite 2000, Hamilton, ON L8P 1H1, Canada
Expert Rev Pharmacoecon Outcomes Res 10:379-84. 2010.... - Cost-effectiveness of alternative treatments for women with osteoporosis in CanadaRon Goeree
Program for Assessment of Technology in Health PATH, McMaster University, Ontario, Canada
Curr Med Res Opin 22:1425-36. 2006..During the years following menopause, estrogen levels decline leading to accelerated bone loss and an increased risk of osteoporosis and osteoporosis-related fractures... - Photodynamic therapy for Barrett's esophagus with high-grade dysplasia: a cost-effectiveness analysisDan Comay
Department of Medicine, Divison of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
Can J Gastroenterol 21:217-22. 2007..To assess the cost-effectiveness of photodynamic therapy (PDT) and esophagectomy (ESO) relative to surveillance (SURV) for patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD)... - Cost-effectiveness of physiologic pacing: results of the Canadian Health Economic Assessment of Physiologic PacingGordon Blackhouse
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Heart Rhythm 2:270-5. 2005..The selective use of these devices in patients likely to be pacemaker dependent appears to be cost-effective. Further studies with longer follow-up and which consider the benefit of reducing nonfatal cardiac events would be valuable... - Cost analysis of multiplex PCR testing for diagnosing respiratory virus infectionsJames B Mahony
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
J Clin Microbiol 47:2812-7. 2009..We conclude that the use of the xTAG RVP test is the least costly strategy for the diagnosis of respiratory virus infections in children and would generate a significant savings for hospitals... - Managing multiple projects: a literature review of setting priorities and a pilot survey of healthcare researchers in an academic settingRobert Borden Hopkins
Program for the Assessment of Technology in Health, McMaster University, Hamilton, Ontario, Canada
Perspect Health Inf Manag 4:4. 2007..To summarize and then assess with a pilot study the use of published best practice recommendations for priority setting during management of multiple healthcare research projects, in a resource-constrained environment... - Economic evaluation of rivastigmine in patients with Parkinson's disease dementiaAndrew R Willan
SickKids Research Institute and Department of Public Health Sciences, Programme in Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
Pharmacoeconomics 24:93-106. 2006..Patient-level healthcare utilisation data were also collected, and this report is the economic evaluation based on these data... - Methods for patient-level costing in the VA system: are they applicable to Canada?Gordon Blackhouse
McMaster University, St. Joseph's Hospital
Med Care Res Rev 60:142S-145S. 2003 - Assessing the impact of censoring of costs and effects on health-care decision-making: an example using the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) studyElisabeth Fenwick
University of Glasgow, Glasgow, UK
Value Health 11:365-75. 2008.... - Economics methods in the Clinical Outcomes Utilizing percutaneous coronary Revascularization and Aggressive Guideline-driven drug Evaluation (COURAGE) trialWilliam S Weintraub
Atlanta VA Medical Center, Decatur, GA, USA
Am Heart J 151:1180-5. 2006..A multilevel regression model will assess cost-effectiveness from a net benefit perspective. These approaches should provide the most detailed assessment available of the cost-effectiveness of PCI for coronary artery disease... - Thinking outside the box: recent advances in the analysis and presentation of uncertainty in cost-effectiveness studiesAndrew H Briggs
Health Economics Research Centre, Department of Public Health, University of Oxford, Oxford OX3 7LF, United Kingdom
Annu Rev Public Health 23:377-401. 2002..Finally, we outline some of the challenges for future research in this area-particularly in relation to the appropriate use of Bayesian methods and methods for analyzing costs that are typically skewed and often incomplete...