Anneliese D Recklies

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes
    Douglas R Houston
    Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland
    J Biol Chem 278:30206-12. 2003
  2. ncbi Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells
    A D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, 1529 Cedar Avenue, Montreal, Quebec, H3G 1A6, Canada
    Biochem J 354:17-24. 2001
  3. ncbi The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways
    Anneliese D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, 1529 Cedar Avenue, Montreal, QC, Canada H3G 1A6
    Biochem J 365:119-26. 2002
  4. ncbi Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes
    Anneliese D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, McGill University, Montreal, Quebec, Canada
    J Biol Chem 280:41213-21. 2005
  5. ncbi Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage
    Lisbet Haglund
    Shriners Hospital for Children, 1529 Cedar Ave, Montreal, QC, Canada H3G 1A6
    Matrix Biol 27:107-18. 2008
  6. ncbi The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
    Hua Ling
    Joint Diseases Laboratory, Shriners Hospital for Children and Department of Surgery, McGill University, Montreal, , Canada
    Biochem J 380:651-9. 2004
  7. ncbi Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism
    Robert Sztrolovics
    Joint Diseases Laboratory, Shriners Hospital for Children, McGill University, Montreal, Quebec, Canada H3G 1A6
    Biochem J 362:473-9. 2002

Collaborators

Detail Information

Publications7

  1. ncbi Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes
    Douglas R Houston
    Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland
    J Biol Chem 278:30206-12. 2003
    ..Thus, HCGP39 could be a lectin that binds chitin-like oligosaccharide ligands and possibly plays a role in innate responses to chitinous pathogens, such as fungi and nematodes...
  2. ncbi Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells
    A D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, 1529 Cedar Avenue, Montreal, Quebec, H3G 1A6, Canada
    Biochem J 354:17-24. 2001
    ..In addition, regulation of HA biosynthesis appears to be multi-faceted, with control of HAS gene expression and mRNA levels being only one aspect of this process...
  3. ncbi The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways
    Anneliese D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, 1529 Cedar Avenue, Montreal, QC, Canada H3G 1A6
    Biochem J 365:119-26. 2002
    ..Thus HC-gp39 initiates a signalling cascade in connective-tissue cells which leads to increased cell proliferation, suggesting that this protein could play a major role in the pathological conditions leading to tissue fibrosis...
  4. ncbi Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes
    Anneliese D Recklies
    Joint Diseases Laboratory, Shriners Hospital for Children, McGill University, Montreal, Quebec, Canada
    J Biol Chem 280:41213-21. 2005
    ....
  5. ncbi Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage
    Lisbet Haglund
    Shriners Hospital for Children, 1529 Cedar Ave, Montreal, QC, Canada H3G 1A6
    Matrix Biol 27:107-18. 2008
    ..This could influence the erosive processes leading to cartilage degeneration as well as the repair of damaged matrix...
  6. ncbi The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
    Hua Ling
    Joint Diseases Laboratory, Shriners Hospital for Children and Department of Surgery, McGill University, Montreal, , Canada
    Biochem J 380:651-9. 2004
    ..This process could therefore be responsible for the down-regulation of cytokine signalling by HC-gp39. These results suggest a physiological role for HC-gp39 in limiting the catabolic effects of inflammatory cytokines...
  7. ncbi Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism
    Robert Sztrolovics
    Joint Diseases Laboratory, Shriners Hospital for Children, McGill University, Montreal, Quebec, Canada H3G 1A6
    Biochem J 362:473-9. 2002
    ..It is likely that both mechanisms contribute to cartilage metabolism in normal physiology and pathology...