Research Topics
| Béatrice Assouline-ThomasSummaryAffiliation: McGill University Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Production and characterization of the recombinant Islet Neogenesis Associated Protein (rINGAP)Béatrice Assouline-Thomas
Department of Surgery, McGill University, Montreal, Que, Canada H3G1A4
Protein Expr Purif 69:1-8. 2010..Importantly, we show that rINGAP exhibits 100x the bioactivity of INGAP peptide on a molar basis in an in vitro assay of human islet regeneration...
Epidermal growth factor induces adult human islet cell dedifferentiationStephen C Hanley
Department of Surgery, McGill University, Montreal, Quebec, Canada Centre for Pancreatic Diseases, McGill University Health Centre, Montreal, Quebec, Canada Jewish General Hospital, Montreal, Quebec, Canada
J Endocrinol 211:231-9. 2011..Thus, in our model, EGF is necessary for islet cell dedifferentiation, playing an important role in both the onset of DLS formation (through JNK) and in the proliferation of these dedifferentiated cells (through AKT and ERK)...
