Research Topics
| S J LupienSummaryCountry: Canada Publications
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Publications
Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivityS J Lupien
Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
J Clin Endocrinol Metab 82:2070-5. 1997..They also suggest that an altered cortisol responsivity to acute and/or chronic stress, with its detrimental effects on memory, could be an important factor explaining the genesis of memory deficits in aged populations...
The acute effects of corticosteroids on cognition: integration of animal and human model studiesS J Lupien
Research Center, Douglas Hospital Research Center, McGill University, Montreal, Quebec, Canada
Brain Res Brain Res Rev 24:1-27. 1997....
Stress, memory, and the hippocampus: can't live with it, can't live without itS J Lupien
Research Center, Douglas Hospital Research Center, Department of Psychiatry, McGill University, Verdun, Quebec, Canada H4H 1R3
Behav Brain Res 127:137-58. 2001....
Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humansS J Lupien
Research Center, Douglas Hospital McGill University and Montreal Geriatric Institute, Quebec, Canada
Behav Neurosci 113:420-30. 1999....
The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognitionS J Lupien
Center for Studies on Human Stress, Douglas Hospital Research Center, McGill University, Montreal, QC, Canada
Brain Cogn 65:209-37. 2007....
Multiparity reveals the blunting effect of breastfeeding on physiological reactivity to psychological stressM T Tu
Department of Neurology and Neurosurgery, Department of Psychiatry, McGill University, Douglas Hospital Research Centre, Montreal, Canada
J Neuroendocrinol 18:494-503. 2006..This would serve to 'desensitise' stress circuits and reduce the overall stress-induced cortisol secretion after multiple births...
Depressive symptoms, cortisol, and cognition during human aging: the role of negative aging perceptionsS Sindi
Centre for Studies on Human Stress, Mental Health Research Centre Fernand Seguin, Hospital Louis H Lafontaine, Montreal, Quebec, Canada
Stress 15:130-7. 2012..These results indicate that the mechanism underlying the association between internalized negative aging stereotypes and cognitive impairments may not be related to dysregulations of cortisol secretion among older adults...
Acute modulation of aged human memory by pharmacological manipulation of glucocorticoidsS J Lupien
Laboratory of Human Psychoneuroendocrine Research, Douglas Hospital Research Center, Department of Psychiatry, McGill University, LaSalle, Verdun, Quebec H4H 1R3, Canada
J Clin Endocrinol Metab 87:3798-807. 2002..These results suggest that memory function in elderly humans can be intensely modulated by pharmacological manipulation of glucocorticoids, although the direction of these effects depends on the cortisol history of each individual...
Successful ageing: from cell to selfS J Lupien
Laboratory of Human Stress Research, Douglas Hospital Research Center, Department of Psychiatry, McGill University, 6875 Boulevard LaSalle, Montreal, Quebec H4H 1R3, Canada
Philos Trans R Soc Lond B Biol Sci 359:1413-26. 2004..This ageism view has been observed in each sphere of science, from genetics to social sciences. Perspectives from each domain are described, and new integrative views of successful ageing are summarized...
Hippocampal volume is as variable in young as in older adults: implications for the notion of hippocampal atrophy in humansS J Lupien
Center for Studies on Human Stress, Douglas Hospital Research Center, McGill University, 6875 Blvd LaSalle, Montreal, Quebec, Canada H4H 1R3
Neuroimage 34:479-85. 2007....
