Research Topics
| J LachaineSummaryCountry: Canada Publications
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Publications
Study protocol of the YOU CALL--WE CALL TRIAL: impact of a multimodal support intervention after a "mild" strokeAnnie Rochette
Montreal University, Montreal, Quebec, Canada
BMC Neurol 10:3. 2010....
Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapyJean Lachaine
Faculty of Pharmacy, University of Montreal, P O Box 6128, Succursale Centre Ville, Montreal, Quebec, Canada
Am J Health Syst Pharm 59:1837-46. 2002..The analysis supported the concomitant use of a corticosteroid, twice-daily administration of ondansetron, and limitation of ondansetron administration to a period not exceeding four days...
Use, tolerability and compliance of spironolactone in the treatment of heart failureJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
BMC Clin Pharmacol 11:4. 2011..The aim of this study was to estimate use of spironolactone by patients with HF, incidence of key adverse events, and patient compliance...
Clinical and economic characteristics of patients with fibromyalgia syndromeJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Canada
Clin J Pain 26:284-90. 2010..The objectives of this study were to estimate prevalence of comorbidities, healthcare resources utilization, and costs associated with FMS...
Choices, persistence and adherence to antihypertensive agents: evidence from RAMQ dataJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec
Can J Cardiol 24:269-73. 2008..Given the need for long-term use of antihypertensive agents, treatment compliance should also be taken into consideration in the selection process...
Painful neuropathic disorders: an analysis of the Régie de l'Assurance Maladie du Québec databaseJ Lachaine
University of Montreal, Montreal, Quebec, Canada
Pain Res Manag 12:31-7. 2007..In most cases, PNDs involve the peripheral nerves. Treatment of PNDs is likely to use large health care resources. However, little is known about the economic burden of PNDs in Canada...
Economic evaluation of the impact of memantine on time to nursing home admission in the treatment of Alzheimer diseaseJean Lachaine
University of Montreal, Quebec
Can J Psychiatry 56:596-604. 2011..Our study aimed to evaluate the economic impact of the concomitant use of memantine and a ChEI, compared with a ChEI alone, in a Canadian population of patients with AD...
Defining monetary values for quality of life improvements: an exploratory studyJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Pharmacoeconomics 21:865-74. 2003..Objective: To explore the feasibility of assessing the monetary value of an intervention by translating the improvement in QOL it produces into willingness to pay (WTP) amounts...
Therapeutic options for the prevention and treatment of postoperative nausea and vomiting: a pharmacoeconomic reviewJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Pharmacoeconomics 24:955-70. 2006..Many questions remain unanswered about the cost effectiveness of existing antiemetics and their regimens, and little is known about the impact of new agents, such as the neurokinin-1 receptor antagonists, in the control of PONV...
Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec dataJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Am Heart J 152:164-9. 2006..There is a concern that poor compliance to cholesterol lowering agents (CLA) may compromise their potential benefits. The objective of this study was to estimate compliance to CLAs, in the context of clinical practice in Quebec...
Systematic review of pharmacoeconomic studies of pharmacogenomic testsMathieu Beaulieu
Faculte de Pharmacie, Universite de Montreal, PO Box 6128, Succ Centre Ville, Montreal, Quebec, H3C 3J7, Canada
Pharmacogenomics 11:1573-90. 2010..In order to fully assess all aspects of pharmacogenomic testing, future pharmacoeconomic assessments should include every specific component that has an impact on the incremental cost-effectiveness ratio...
Economic impact of the advent of posterior lamellar keratoplasty in Montreal, QuebecCatherine Beauchemin
Faculty of Pharmacy, University of Montreal, Montreal, Que
Can J Ophthalmol 45:243-51. 2010....
A model for assessing the cost-effectiveness of atorvastatin and simvastatin in achieving Canadian low-density lipoprotein cholesterol targetsJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Clin Ther 29:519-28. 2007..Statins differ in their LDL-C-lowering effects and acquisition costs. Atorvastatin and simvastatin are the 2 most commonly used statins in Canada...
Cost of corneal transplantation for the Quebec health care systemJean Pascal F Roussy
Faculty of Pharmacy, University of Montreal, Montreal, Que
Can J Ophthalmol 44:36-41. 2009..The purpose of this study was to estimate resource use and costs associated with corneal transplantation according to a public third-party perspective...
Do proton-pump inhibitors increase the risk for nosocomial pneumonia in a medical intensive care unit?Mathieu Beaulieu
Faculty of Pharmacy, Universite de Montreal, Hopital du Sacre Coeur de Montreal, Quebec, Canada
J Crit Care 23:513-8. 2008..The aim of this study was to determine whether the use of gastric acid-suppressive agents increases the risk of nosocomial pneumonia (NP) in a medical intensive care unit population...
Risk of Clostridium difficile-associated disease among patients receiving proton-pump inhibitors in a Quebec medical intensive care unitMathieu Beaulieu
Faculty of Pharmacy, Universite de Montreal, Montreal, QC, H3C 3J7, Canada
Infect Control Hosp Epidemiol 28:1305-7. 2007..Our findings suggest that efforts to determine risk factors for CDAD should focus on other areas, such as older age and antibiotic use...
Economic impact of Tibolone compared with Continuous-Combined Hormone Replacement Therapy in the management of climacteric symptoms in postmenopausal womenVakaramoko Diaby
Faculty of Pharmacy, University of Montreal, Centre Ville, Montreal, QC H3C 3J7, Canada
Maturitas 58:138-49. 2007..It has been used in Europe, in the same indication as CCHRT, for approximately 20 years but is not yet available in Canada...
Prostaglandin analogues for ophthalmic use: a cost-effectiveness analysisJean Lachaine
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Quebec, Canada
Can J Ophthalmol 43:33-41. 2008..An important policy decision is whether to support continued open listing of these agents or to restrict them to limited use status...
Determinants of adherence to glaucoma medical therapy in a long-term patient populationFawzia Djafari
Department of Ophthalmology, University of Montreal, Quebec, Canada
J Glaucoma 18:238-43. 2009..Estimate patient adherence to glaucoma medications and identify potential determinants of nonadherence...
Interprofessional health care teams: attitudes and environmental factors associated with participation by community pharmacistsRoy T Dobson
College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Interprof Care 20:119-32. 2006....
