Research Topics
| D A AlterSummaryAffiliation: Institute for Clinical Evaluative Sciences Country: Canada Publications
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Detail Information
Publications
Influence of socioeconomic status on lifestyle behavior modifications among survivors of acute myocardial infarctionRaymond H M Chan
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
Am J Cardiol 102:1583-8. 2008..In conclusion, socioeconomically disadvantaged patients were sicker at baseline and less behaviorally responsive to embarking on healthy lifestyle changes after AMI than were those of higher socioeconomic status...
Impact of clinical urgency, physician supply and procedural capacity on regional variations in wait times for coronary angiographyHarindra C Wijeysundera
Sunnybrook Health Sciences Center, 2075 Bayview Avenue, Toronto, Ontario, Canada
BMC Health Serv Res 10:5. 2010..Our objective was to evaluate the extent to which demand-side factors such as clinical urgency/need, and supply-side factors, as reflected by differences in physician and procedural supply account for these inequalities...
The relationship between depressive symptoms, health service consumption, and prognosis after acute myocardial infarction: a prospective cohort studyPaul A Kurdyak
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, Canada
BMC Health Serv Res 8:200. 2008..This paper explores the relationship between depressive symptoms, health service cardiovascular consumption, and prognosis following acute myocardial infarction (AMI)...
Triage for coronary artery bypass graft surgery in Canada: do patients agree on who should come first?Katy Shufelt
Schulich Heart Program of Sunnybrook Health Sciences Centre, Toronto, Canada
BMC Health Serv Res 7:118. 2007....
Community factors, hospital characteristics and inter-regional outcome variations following acute myocardial infarction in CanadaDavid A Alter
University of Toronto, Toronto, Canada
Can J Cardiol 21:247-55. 2005....
The relationship between the supply of fast-food chains and cardiovascular outcomesDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, ON
Can J Public Health 96:173-7. 2005..To examine the extent to which inter-regional differences in fast-food concentrations account for variations in all-cause mortality and acute coronary syndromes throughout Ontario, Canada...
The evaluation of a formalized queue management system for coronary angiography waiting listsD A Alter
Institute for Clinical Evaluative Sciences, Toronto, Canada
Can J Cardiol 21:1203-9. 2005..The extent to which formal queue management systems may improve the prioritization and survival of patients in the angiography queue is unknown...
Socioeconomic status and mortality after acute myocardial infarctionDavid A Alter
Institute for Clinical Evaluative Sciences, Sunnybrook, Women s College Health Sciences Centre, York University, Institute for Work and Health, and University of Toronto, Toronto, Ontario, Canada
Ann Intern Med 144:82-93. 2006..The intermediary causes of such gradients remain poorly elucidated...
Proliferation of cardiac technology in Canada: a challenge to the sustainability of MedicareDavid A Alter
Institute for Clinical Evaluative Sciences, The University of Toronto Clinical Epidemiology and Health Care Research Program, Toronto, Canada
Circulation 113:380-7. 2006..The objective of this study was to examine the temporal trends in the utilization and costs of cardiovascular technologies for the evaluation and/or management of patients with ischemic heart disease in Canada...
Relationship between cardiac rehabilitation and survival after acute cardiac hospitalization within a universal health care systemDavid A Alter
Institute for Clinical Evaluative Sciences, Sunnybrook Health Science Centre, Toronto, Ontario, Canada
Eur J Cardiovasc Prev Rehabil 16:102-13. 2009..The magnitude and mechanisms of survival benefit associated with cardiac rehabilitation services among real-world populations within a universal health care system remain unclear...
Factors explaining the under-use of reperfusion therapy among ideal patients with ST-segment elevation myocardial infarctionDavid A Alter
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
Eur Heart J 27:1539-49. 2006....
Therapeutic lifestyle and disease-management interventions: pushing the scientific envelopeDavid A Alter
Institute for Clinical Evaluative Sciences, St. Michael's Hospital, University of Toronto, Toronto, Ont
CMAJ 177:887-9. 2007
The relationship between physician supply, cardiovascular health service use and cardiac disease burden in Ontario: supply-need mismatchDavid A Alter
Institute for Clinical Evaluative Sciences, University of Toronto, Ontario
Can J Cardiol 24:187-93. 2008..The objective of the present study was to examine the relationship among cardiovascular evaluation and management intensity, physician supply and cardiovascular disease burden in the Canadian population...
Lesson from Canada's Universal Care: socially disadvantaged patients use more health services, still have poorer healthDavid A Alter
Institute for Clinical Evaluative Sciences and the research director of theCardiac Rehabilitation and Secondary Prevention Program of the Toronto Rehabilitation Institute, inToronto, Ontario, Canada
Health Aff (Millwood) 30:274-83. 2011..Universal access can only reduce these disparities. Our findings suggest the need to introduce large-scale preventive strategies early in patients' lives to help change unhealthy behavior...
Age, risk-benefit trade-offs, and the projected effects of evidence-based therapiesDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am J Med 116:540-5. 2004..We compared the estimated effects of age and efficacy of treatment on survival among patients with acute coronary syndromes...
Socioeconomic status, service patterns, and perceptions of care among survivors of acute myocardial infarction in CanadaDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
JAMA 291:1100-7. 2004..The extent to which this theory is a valid representation of Canadian health care is unknown...
Influence of education and income on atherogenic risk factor profiles among patients hospitalized with acute myocardial infarctionDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Can J Cardiol 20:1219-28. 2004..It is unknown whether these differences can be attributed, in part, to variations in the prevalence of atherogenic risk factors preceding the index AMI event...
Factoring socioeconomic status into cardiac performance profiling for hospitals: does it matter?David A Alter
Division of Cardiology, Schulich Heart Centre, University of Toronto, Ontario
Med Care 40:60-7. 2002....
Waiting times, revascularization modality, and outcomes after acute myocardial infarction at hospitals with and without on-site revascularization facilities in CanadaDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Coll Cardiol 42:410-9. 2003..This study was designed to determine whether admission to a Canadian hospital with on-site revascularization (invasive hospital) affected revascularization choice, timing, and outcome compared with community (non-invasive) hospitals...
Biology or bias: practice patterns and long-term outcomes for men and women with acute myocardial infarctionD A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Coll Cardiol 39:1909-16. 2002..Another objective was to evaluate the association of age, gender and treatment intensity with five-year survival after AMI...
Geography and service supply do not explain socioeconomic gradients in angiography use after acute myocardial infarctionDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ont, Canada
CMAJ 168:261-4. 2003..This study was conducted to determine whether the impact of socioeconomic status on angiography use would be lessened by considering variations in the supply of services...
Processes and outcomes of care for diabetic acute myocardial infarction patients in Ontario: do physicians undertreat?David A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Diabetes Care 26:1427-34. 2003..To compare the health service utilization and long-term outcomes of acute myocardial infarction (AMI) patients with and without diabetes in Ontario...
Long-term MI outcomes at hospitals with or without on-site revascularizationD A Alter
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
JAMA 285:2101-8. 2001..Whether such differences are due to invasive procedure rates alone or to other patient, physician, and hospital characteristics is unknown...
Evaluating the performance of the Global Registry of Acute Coronary Events risk-adjustment index across socioeconomic strata among patients discharged from the hospital after acute myocardial infarctionDavid A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 151:323-31. 2006....
Comparing hierarchical modeling with traditional logistic regression analysis among patients hospitalized with acute myocardial infarction: should we be analyzing cardiovascular outcomes data differently?Peter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 145:27-35. 2003..Conventional logistic regression tended to increase the statistical significance for the effects of variables measured at the hospital-level compared to the level of significance indicated by the multilevel model...
Clinical prognosis, pre-existing conditions and the use of reperfusion therapy for patients with ST segment elevation acute myocardial infarctionAndrea B Parker
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Can J Cardiol 22:131-9. 2006..These findings are consistent with the view that these clinical decisions are more likely to be attributable to concerns about patient frailty or side effects than to a misunderstanding of treatment benefits...
Utilisation of coronary angiography after acute myocardial infarction in Ontario over time: have referral patterns changed?Y Khaykin
Division of Cardiology, Schulich Heart Centre, Sunnybrook and Women's College Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada
Heart 88:460-6. 2002..Wider implementation of data monitoring and explicit management systems may be required to ensure that appropriate utilisation of cardiac services is allocated to patients who are most in need...
Age-social stratification designs had a negligible impact on income-mortality associationsH C Wijeysundera
Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada
J Clin Epidemiol 60:579-84. 2007..This study was to evaluate whether age-income stratification designs generate comparable income-mortality associations as those whose income rankings are based on absolute thresholds...
Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarctionJeppe N Rasmussen
Institute of Clinical Evaluative Sciences, Toronto, Ontario, Canada
JAMA 297:177-86. 2007..The extent to which drug adherence may affect survival remains unclear, in part because mortality differences may be attributable to "healthy adherer" behavioral attributes more so than to pharmacological benefits...
Temporal trends in the use of percutaneous coronary intervention and coronary artery bypass surgery in New York State and OntarioDennis T Ko
Institute for Clinical Evaluative Sciences, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Ontario, Canada
Circulation 121:2635-44. 2010..Although New York State (NYS) historically has had twice as many coronary revascularizations performed as Ontario, the relative evolution of coronary revascularization patterns in both jurisdictions over time is unknown...
Risk-treatment mismatch in the pharmacotherapy of heart failureDouglas S Lee
Institute for Clinical Evaluative Sciences, Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada
JAMA 294:1240-7. 2005..Understanding the reasons underlying this mismatch may facilitate improvements in care and outcomes for patients with heart failure...
Lipid-lowering therapy with statins in high-risk elderly patients: the treatment-risk paradoxDennis T Ko
Division of Cardiology, Schulich Heart Centre, and Department of Medicine, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario
JAMA 291:1864-70. 2004..Since the benefits of a therapy are dependent on the baseline risk, the maximum benefits of statins may not be fully realized until implementation of therapy includes patients at highest risk...
Patient satisfaction and its relationship with quality and outcomes of care after acute myocardial infarctionDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Circulation 118:1938-45. 2008....
Cardiologists' charting varied by risk factor, and was often discordant with patient reportShannon Gravely-Witte
University Health Network Women s Health Program, 200 Elizabeth St, Toronto, Ontario, Canada
J Clin Epidemiol 61:1073-9. 2008..To assess the completeness of cardiac risk factor documentation by cardiologists, and agreement with patient report...
Early deaths in patients with heart failure discharged from the emergency department: a population-based analysisDouglas S Lee
Division of Cardiology, Institute for Clinical Evaluative Sciences, Toronto General Hospital, Toronto, Ontario, Canada
Circ Heart Fail 3:228-35. 2010..Although approximately one third of patients with heart failure (HF) visiting the emergency department (ED) are discharged home, little is known about their care and outcomes...
Effect of widespread restrictions on the use of hospital services during an outbreak of severe acute respiratory syndromeMichael J Schull
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 176:1827-32. 2007..We describe the impact of these restrictions on health care utilization and suggest lessons for future epidemics...
Factors associated with the use of evidence-based therapies after discharge among elderly patients with myocardial infarctionPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 179:901-8. 2008..Our objective was to identify the characteristics of patients, physicians, hospitals and communities associated with differences in the use of these medications after discharge...
Effect of cardiac and noncardiac conditions on survival after defibrillator implantationDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Coll Cardiol 49:2408-15. 2007..We sought to examine outcomes in recipients of implantable cardioverter-defibrillators (ICDs) and the effect of age, gender, and comorbidities on survival...
Use of evidence-based therapies after discharge among elderly patients with acute myocardial infarctionPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 179:895-900. 2008..We examined trends in the use of evidence-based drug therapies after discharge among elderly patients with myocardial infarction...
Health impact of hospital restrictions on seriously ill hospitalized patients: lessons from the Toronto SARS outbreakTherese A Stukel
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Med Care 46:991-7. 2008..Restrictions on non-urgent hospital care imposed to control the 2003 Toronto severe acute respiratory syndrome outbreak led to substantial disruptions in hospital clinical practice, admission, and transfer patterns...
Improved outcomes with early collaborative care of ambulatory heart failure patients discharged from the emergency departmentDouglas S Lee
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, ON, M4N 3M5, Canada
Circulation 122:1806-14. 2010..The type of outpatient physician care after an emergency department visit for heart failure may affect patients' outcomes. Methods and..
Thiazolidinediones and cardiovascular outcomes in older patients with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
JAMA 298:2634-43. 2007..However, the association between TZD use and cardiovascular events has not been adequately evaluated on a population level...
"Dose-dependent" impact of recurrent cardiac events on mortality in patients with heart failureDouglas S Lee
Institute for Clinical Evaluative Sciences, Ont, Canada
Am J Med 122:162-169.e1. 2009..We determined if a "dose-dependent" relationship exists between heart failure events and death, accounting for temporal changes in age, comorbidities, and disease severity...
Effectiveness of public report cards for improving the quality of cardiac care: the EFFECT study: a randomized trialJack V Tu
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
JAMA 302:2330-7. 2009..Publicly released report cards on hospital performance are increasingly common, but whether they are an effective method for improving quality of care remains uncertain...
Influence of socioeconomic status on drug selection for the elderly in CanadaMuhammad M Mamdani
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G215, Toronto, Ontario M4N 3M5, Canada
Ann Pharmacother 36:804-8. 2002....
Secular trends in acute coronary syndrome hospitalization from 1994 to 2005Dennis T Ko
Institute for Clinical Evaluative Sciences, Toronto, Ontario
Can J Cardiol 26:129-34. 2010..Although substantial advances have been made in the prevention and treatment of coronary artery disease, their impact on the rates of ACS hospitalization is unclear...
Association between hospital cardiac management and outcomes for acute myocardial infarction patientsTherese A Stukel
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
Med Care 48:157-65. 2010..Randomized trials have shown that medical and interventional therapies improve outcomes for acute myocardial infarction (AMI) patients. The extent to which hospital quality improvement translates into better patient outcomes is unclear...
Regional variation in cardiac catheterization appropriateness and baseline risk after acute myocardial infarctionDennis T Ko
Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Am Coll Cardiol 51:716-23. 2008....
Impact of the choice of benchmark on the conclusions of hospital report cardsPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 148:1041-6. 2004..The objective of the current study was to determine whether the number of hospitals identified as mortality outliers depended upon the benchmark against which hospitals are compared...
Coronary angiography following acute myocardial infarction in Ontario, CanadaSheldon M Singh
Departments of Medicine, University of Toronto, Toronto, Ontario, Canada
Arch Intern Med 167:808-13. 2007..The role of scientific evidence in shaping recommendations on capacity targets and cardiovascular technology utilization is unclear...
The use of fixed- and random-effects models for classifying hospitals as mortality outliers: a Monte Carlo assessmentPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Med Decis Making 23:526-39. 2003..There is an increasing movement towards the release of hospital "report-cards. "However, there is a paucity of research into the abilities of the different methods to correctly classify hospitals as performance outliers...
Association between lipid testing and statin therapy in acute myocardial infarction patientsDennis T Ko
Division of Cardiology, Schulich Heart Centre, Toronto, Ontario, Canada
Am Heart J 150:419-25. 2005..We sought to examine rates of inhospital lipid testing and its association with statin therapy at hospital discharge...
The impact of under coding of cardiac severity and comorbid diseases on the accuracy of hospital report cardsPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Med Care 43:801-9. 2005..Hospital report cards usually are based on administrative discharge abstracts. However, cardiac severity and comorbidities generally are under-reported in administrative data...
Socioeconomic status influences care of patients with acne in Ontario, CanadaAamir Haider
Division of Dermatology, University of Toronto, Toronto, Ontario, Canada
J Am Acad Dermatol 54:331-5. 2006..CONCLUSION: Within Canada's universal health care system, those likely to be in lower socioeconomic groups are significantly less likely to visit a dermatologist for specialist consultation...
Outcomes of acute myocardial infarction in CanadaJack V Tu
Sunnybrook and Women s College Health Sciences Centre, Toronto, Canada
Can J Cardiol 19:893-901. 2003..Little information is available on recent population-based trends in the outcomes of patients who have had an acute myocardial infarction (AMI) in Canada...
Revisiting Rose: strategies for reducing coronary heart diseaseDouglas G Manuel
Institute for Clinical Evaluative Sciences, G106-2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5
BMJ 332:659-62. 2006
The use of quantile regression in health care research: a case study examining gender differences in the timeliness of thrombolytic therapyPeter C Austin
Institute for Clinical Evaluative Sciences, Canada
Stat Med 24:791-816. 2005..Investigators who want to determine how a distribution of delays in treatment or of waiting times changes with patient or system characteristics should consider complementing their analyses with the use of quantile regression...
Missed opportunities in the secondary prevention of myocardial infarction: an assessment of the effects of statin underprescribing on mortalityPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 151:969-75. 2006..We explored the potential reduction in mortality at the population level that could result from improving statin prescribing among patients least likely to be prescribed a statin after acute myocardial infarction (AMI)...
The 2003 Canadian recommendations for dyslipidemia management: revisions are neededDouglas G Manuel
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 172:1027-31. 2005
Effectiveness and efficiency of different guidelines on statin treatment for preventing deaths from coronary heart disease: modelling studyDouglas G Manuel
Institute for Clinical Evaluative Sciences G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5
BMJ 332:1419. 2006..To examine the potential effectiveness and efficiency of different guidelines for statin treatment to reduce deaths from coronary heart disease in the Canadian population...
Life expectancy after an index hospitalization for patients with heart failure: a population-based studyDennis T Ko
Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Am Heart J 155:324-31. 2008..However, previous studies have focused on predicting shorter-term mortality and limited data currently exist to predict expected survival among hospitalized patients with HF...
Regional differences in process of care and outcomes for older acute myocardial infarction patients in the United States and Ontario, CanadaDennis T Ko
Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Circulation 115:196-203. 2007....
Analysis of observational studies in the presence of treatment selection bias: effects of invasive cardiac management on AMI survival using propensity score and instrumental variable methodsTherese A Stukel
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
JAMA 297:278-85. 2007..Comparisons of outcomes between patients treated and untreated in observational studies may be biased due to differences in patient prognosis between groups, often because of unobserved treatment selection biases...
The relationship between unprovoked venous thromboembolism, age, and acute myocardial infarctionF A Spencer
Department of Medicine, McMaster University Medical Center, Hamilton, ON, Canada
J Thromb Haemost 6:1507-13. 2008..However, the nature and clinical significance of this association remain unclear, particularly as it relates to age of presentation...
Design and implementation of a population-based registry of Implantable Cardioverter Defibrillators (ICDs) in OntarioDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Ontario, M4N 3M5 Canada
Heart Rhythm 5:1250-6. 2008..There are scarce population-based data on the use, complication rates, and outcomes of patients receiving implantable cardioverter defibrillators (ICDs)...
The economic burden of obesity worldwide: a systematic review of the direct costs of obesityD Withrow
Department of Life Sciences, Queen s University, Toronto, ON, Canada
Obes Rev 12:131-41. 2011..Accordingly, future studies must better explore how costs accrue among obese populations, in order to best facilitate health and social policy interventions...
Both clinical epidemiology and population health perspectives can define the role of health care in reducing health disparitiesGeoffrey M Anderson
Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, McMurrich Building, 2nd Floor, 12 Queen s Park Crescent West, Toronto, Ontario M5S 1A8, Canada
J Clin Epidemiol 58:757-62. 2005..To compare and contrast clinical epidemiology and population health perspectives on the role of health care in reducing socioeconomic disparities in health...
Do case-generic measures of queue performance for bypass surgery accurately reflect the waiting-list experiences of those most urgent?Jason Burstein
University of Toronto, Toronto, Canada
J Eval Clin Pract 12:87-93. 2006..Our results reinforce the concept that urgency-specific waiting list monitoring systems are required to best evaluate and appropriately respond to fluctuations in queue performance...
Contribution of patient and physician factors to cardiac rehabilitation enrollment: a prospective multilevel studySherry L Grace
York University, 4700 Keele St, Toronto, Ontario M3J 1P3, Canada
Eur J Cardiovasc Prev Rehabil 15:548-56. 2008..This is due to both health system and patient-level factors; issues that have yet to be investigated concurrently. This study utilized a hierarchical design to examine physician and patient-level factors affecting verified CR enrollment...
Effectiveness of implantable defibrillators for preventing arrhythmic events and death: a meta-analysisDouglas S Lee
University of Toronto, Department of Health Policy, Management and Evaluation/Clinical Epidemiology, Toronto, Canada
J Am Coll Cardiol 41:1573-82. 2003..Given the cost of the device strategy, policies of targeted intervention based on the future risk of arrhythmia are warranted...
The impact of implantable cardiac defibrillators for primary prophylaxis in the community: baseline risk and clinically meaningful benefitsS Jolly
St. Michael's Hospital, University of Toronto, Ontario, Canada
J Eval Clin Pract 12:190-5. 2006..CONCLUSIONS: The survival impact and cost-effectiveness of prophylactic ICDs in the population will depend upon the ability to risk-stratify and identify patients whose baseline risk for sudden cardiac death exceed 3% per year...
The importance of echocardiography in physicians' support of endocarditis prophylaxisSheldon M Singh
Department of Medicine, University of Toronto, Ontario, Canada
Arch Intern Med 166:549-53. 2006..Further studies must evaluate the role of echocardiography in the assessment and management of antimicrobial endocarditis prophylaxis to assist in the development of clear clinical guidelines...
Is routine early invasive management of non-ST-segment elevation myocardial infarction beneficial in elderly patients?Sheldon M Singh
Department of Medicine, Sunnybrook and Women's College Health Sciences Centre, University of Toronto Toronto, Ont
CMAJ 171:1046-7. 2004
Are some patients in Canada treated more equally than others? The Orwell prophecyDavid A Alter
Am Heart J 146:938-40. 2003
Antihypertensive therapy and incidence of type 2 diabetes in an elderly cohortRaj Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Diabetes Care 27:2458-63. 2004..The aim of this study was to determine whether the incidence of type 2 diabetes differed among elderly users of four major antihypertensive drug classes...
Addressing the challenges of queuesDalia L Rotstein
CMAJ 166:299-300. 2002
Relation between cardiac troponin I and mortality in acute decompensated heart failureJohn J You
Institute for Clinical Evaluative Sciences, University of Toronto, Ontario, Canada
Am Heart J 153:462-70. 2007..Troponin level elevations are common in patients with acute decompensated heart failure (ADHF), yet their prognostic value above and beyond traditional predictors of outcomes in heart failure is uncertain...
The Smoking Regulatory Index: a new way to measure public health performanceDaniel Rosenfield
Canadian Cardiac Outcomes Research Team and Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 174:1403-4. 2006
Where does the waiting list begin? A short review of the dynamics and organization of modern waiting listsDalia L Rotstein
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Soc Sci Med 62:3157-60. 2006..Real-world examples are used to illustrate the infancy of funnel or demand-side reform initiatives targeting the queue, and the suggestion is made that policy needs to address the concept of 'waiting' much earlier in the treatment cycle...
