A Gupta

Summary

Affiliation: Division of Dermatology
Country: Canada

Publications

  1. ncbi Ciclopirox (Loprox) gel for superficial fungal infections
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens College Health Sciences Centre (Sunnybrook site, University of Toronto, Toronto, ON, Canada
    Skin Therapy Lett 9:4-5, 9. 2004
  2. ncbi Rosacea and its management: an overview
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook Site, Toronto, Canada
    J Eur Acad Dermatol Venereol 19:273-85. 2005
  3. ncbi Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment
    Aditya K Gupta
    University of Toronto, Toronto, Ontario, Canada
    J Am Acad Dermatol 66:494-502. 2012
  4. ncbi Variation in restriction fragment length polymorphisms among serial isolates from patients with Trichophyton rubrum infection
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center, Women s College Hospital, Sunnybrook Site, and University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 39:3260-6. 2001
  5. ncbi Ciclopirox for the treatment of superficial fungal infections: a review
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    Int J Dermatol 42:3-9. 2003
  6. ncbi Arthroconidial formation in Trichophyton raubitschekii
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Ontario, Canada N6K 1L6
    Mycoses 46:322-8. 2003
  7. ncbi Tinea corporis, tinea cruris, tinea nigra, and piedra
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:395-400, v. 2003
  8. ncbi Seborrheic dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
    Dermatol Clin 21:401-12. 2003
  9. ncbi Pityriasis versicolor
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:413-29, v-vi. 2003
  10. ncbi Treatments of tinea pedis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:431-62. 2003

Detail Information

Publications121 found, 100 shown here

  1. ncbi Ciclopirox (Loprox) gel for superficial fungal infections
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens College Health Sciences Centre (Sunnybrook site, University of Toronto, Toronto, ON, Canada
    Skin Therapy Lett 9:4-5, 9. 2004
    ..Ciclopirox is indicated in the US for the treatment of tinea pedis, tinea corporis, pityriasis versicolor, seborrheic dermatitis, and cutaneous candidiasis...
  2. ncbi Rosacea and its management: an overview
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook Site, Toronto, Canada
    J Eur Acad Dermatol Venereol 19:273-85. 2005
    ..Since a cure for rosacea does not yet exist, management and treatment regimens are designed to suppress the inflammatory lesions, erythema, and to a lesser extent, the telangiectasia involved with rosacea...
  3. ncbi Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment
    Aditya K Gupta
    University of Toronto, Toronto, Ontario, Canada
    J Am Acad Dermatol 66:494-502. 2012
    ..When evaluating different treatments, we suggest that authors clearly define their efficacy outcomes...
  4. ncbi Variation in restriction fragment length polymorphisms among serial isolates from patients with Trichophyton rubrum infection
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center, Women s College Hospital, Sunnybrook Site, and University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 39:3260-6. 2001
    ..The recovery of multiple strains during the course of sequential sampling of uncured patients further suggests that the typing system is not able to distinguish between relapse or reinfection, ongoing infection, and de novo infection...
  5. ncbi Ciclopirox for the treatment of superficial fungal infections: a review
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    Int J Dermatol 42:3-9. 2003
    ..The new ciclopirox gel 0.77% formulation is also indicated for the treatment of seborrheic dermatitis of the scalp, interdigital tinea pedis and tinea corporis...
  6. ncbi Arthroconidial formation in Trichophyton raubitschekii
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Ontario, Canada N6K 1L6
    Mycoses 46:322-8. 2003
    ..The availability of arthroconidia in T. raubitschekii cultures appears to offer a practical means of characterizing infective cells in T. rubrum...
  7. ncbi Tinea corporis, tinea cruris, tinea nigra, and piedra
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:395-400, v. 2003
    ..Preventative measures of tinea infections include practicing good personal hygiene; keeping the skin dry and cool at all times; and avoiding sharing towels, clothing, or hair accessories with infected individuals...
  8. ncbi Seborrheic dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
    Dermatol Clin 21:401-12. 2003
    ..The wide range of antifungal formulations available (creams, shampoos, or oral) provides safe, effective, and flexible treatment options for seborrheic dermatitis...
  9. ncbi Pityriasis versicolor
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:413-29, v-vi. 2003
    ..Antifungal preparations have been used to treat the initial presentation effectively, although in a proportion of patients the disease tends to reoccur. They are available in a wide range of formulations and have been shown to be safe...
  10. ncbi Treatments of tinea pedis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:431-62. 2003
    ..In such instances, systemic antifungal therapy is required to ensure that adequate concentrations of the therapeutic agent are present at the site of infection...
  11. ncbi Photodynamic therapy and topical aminolevulinic acid: an overview
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center and the University of Toronto, Toronto, Ontario, Canada
    Am J Clin Dermatol 4:699-708. 2003
    ..Further experience in the use of photodynamic therapy will help define its utility in the management of actinic keratosis and other dermatoses...
  12. ncbi Dermatophytes: diagnosis and treatment
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center, University of Toronto, Canada
    J Am Acad Dermatol 54:1050-5. 2006
  13. ncbi Onychomycosis in children: an overview
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, University of Toronto, Toronto, Canada
    J Drugs Dermatol 2:31-4. 2003
    ..However, these agents appear to be effective and safe in this indication...
  14. ncbi Onychomycosis: strategies to improve efficacy and reduce recurrence
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 16:579-86. 2002
    ..Steps should be taken to reduce the possibility of recurrence once cure has been achieved...
  15. ncbi Comparative efficacies of commonly used disinfectants and antifungal pharmaceutical spray preparations against dermatophytic fungi
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, and the University of Toronto, Ontario, Canada
    Med Mycol 39:321-8. 2001
    ..mentagrophytes strains. Bifonazole (1%) was also fungistatic in its action against T. mentagrophytes. Sodium dodecyl sulphate (0.5%) was largely ineffective against Trichophyton arthroconidia...
  16. ncbi Ciclopirox gel: an update
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center (Sunnybrook site) and the University of Toronto, Toronto, Canada
    Int J Dermatol 42:1-2. 2003
  17. ncbi Itraconazole is effective in the treatment of tinea capitis caused by Microsporum canis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, Toronto, Canada
    Pediatr Dermatol 18:519-22. 2001
    ..Compliance was very good in the patient group. Itraconazole 5 mg/kg/day given either as a capsule or an oral suspension for 4-8 weeks is effective and safe in the treatment of tinea capitis caused by M. canis...
  18. ncbi Pityriasis versicolor
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Science Center, Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 16:19-33. 2002
    ....
  19. ncbi Tacrolimus: a review of its use for the management of dermatoses
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Science Center and University of Toronto, Canada
    J Eur Acad Dermatol Venereol 16:100-14. 2002
    ..This is generally transient and the patient is able to continue with therapy. The other dermatoses where tacrolimus has been used include contact dermatitis, psoriasis and pyoderma gangrenosum...
  20. ncbi Imiquimod: a review
    Aditya K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 6:554-60. 2002
    ....
  21. ncbi Management of toe onychomycosis: what is the potential for improving efficacy of treatment?
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center, Toronto, Ontario, Canada
    Clin Dermatol 20:607-9. 2002
  22. ncbi Alternate week and combination itraconazole and terbinafine therapy for chromoblastomycosis caused by Fonsecaea pedrosoi in Brazil
    A K Gupta
    Division of Dermatology, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
    Med Mycol 40:529-34. 2002
    ..Some success with alternative week therapy was also noted in one patient. The favorable response and lack of significant adverse effects suggests that these regimens may be an option for some patients with chromoblastomycosis...
  23. ncbi Seborrheic dermatitis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Eur Acad Dermatol Venereol 18:13-26; quiz 19-20. 2004
    ..In addition, s/he will be aware of the role of Malassezia yeasts in seborrheic dermatitis and the way in which knowledge of the importance of these yeasts has altered the treatment of this disorder...
  24. ncbi Pityriasis versicolor: quality of studies
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Ontario, Canada
    J Dermatolog Treat 15:40-5. 2004
    ..To evaluate the quality of the published literature on the treatment of pityriasis versicolor and to compare this evaluation with the number of times the work has been cited...
  25. ncbi Dermatophytosis: the management of fungal infections
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Windermere Road, Toronto, Ontario, Canada NSX 2P1
    Skinmed 4:305-10. 2005
    ..Terbinafine, itraconazole, and fluconazole are oral antimycotics that are effective in the treatment of superficial mycoses, although, depending on the severity of the infection, a topical antifungal may be sufficient...
  26. ncbi Diagnosing onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre Sunnybrook Site, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Dermatol Clin 24:365-9. 2006
    ..This article discusses the efficacy of the various methods used for the diagnosis of onychomycosis...
  27. ncbi Onychomycosis therapies: strategies to improve efficacy
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Sunnybrook Site, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Dermatol Clin 24:381-6. 2006
    ..These involve the combination of available therapies and/or a modification of treatment regimens...
  28. ncbi Pulse itraconazole vs. continuous terbinafine for the treatment of dermatophyte toenail onychomycosis in patients with diabetes mellitus
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, University of Toronto and Toronto General Hospital, Canada
    J Eur Acad Dermatol Venereol 20:1188-93. 2006
    ....
  29. ncbi Efalizumab in the treatment of psoriasis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre Sunnybrook Site and the University of Toronto, ON
    J Cutan Med Surg 10:57-68. 2006
    ..Efalizumab has recently been approved in Canada for this indication...
  30. ncbi Position statement for isotretinoin
    Aditya K Gupta
    J Cutan Med Surg 11:123-4. 2007
  31. ncbi Naftifine: a review
    Aditya K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, ON
    J Cutan Med Surg 12:51-8. 2008
    ..Naftifine is fungicidal in vitro against a broad spectrum of dermatophyte fungi and provides good activity against Candida and Aspergillus species. It is also effective against gram-negative and gram-positive bacteria...
  32. ncbi Psoriatic nail disease: quality of life and treatment
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, ON
    J Cutan Med Surg 13:S102-6. 2009
    ..Large-scale, long-term trials using standardized outcome measures are needed to further evaluate biologic therapies for the treatment of nail psoriasis...
  33. ncbi Prednicarbate (Dermatop): profile of a corticosteroid
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook site and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 8:244-7. 2004
    ....
  34. ncbi Ciclopirox topical solution, 8% combined with oral terbinafine to treat onychomycosis: a randomized, evaluator-blinded study
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, Canada
    J Drugs Dermatol 4:481-5. 2005
    ..The data suggest that combination therapy (PL8) may be an alternative regimen to continuous terbinafine (L12) in the treatment of moderate to severe dermatophyte toenail onychomycosis...
  35. ncbi Onychomycosis in children: a brief overview with treatment strategies
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center and University of Toronto, Toronto, Ontario, Canada
    Pediatr Dermatol 21:74-9. 2004
    ..More data are needed on the use of these antifungal agents for the treatment of onychomycosis in children...
  36. ncbi Onychomycosis: classification and diagnosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, and the University of Toronto, Toronto, Canada
    J Drugs Dermatol 3:51-6. 2004
    ..Prior to treatment an accurate diagnosis can provide guidance about the choice of antifungal agent, especially since the causative organism may vary in its response to the antifungal therapies available...
  37. ncbi Seborrhoeic dermatitis: current treatment practices
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    Expert Opin Pharmacother 5:1755-65. 2004
    ..Since the discovery of ketoconazole, a considerable amount of research has been focused on determining the efficacy of various antifungal agents. This article reviews clinical trial data on treatment options available for SD...
  38. ncbi Ciclopirox: a broad-spectrum antifungal with antibacterial and anti-inflammatory properties
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Science Center, University of Toronto, Toronto, Canada
    Int J Dermatol 43:3-8. 2004
  39. ncbi Optimal management of fungal infections of the skin, hair, and nails
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Am J Clin Dermatol 5:225-37. 2004
    ..Terbinafine, itraconazole, and fluconazole are oral antifungals that are effective in the treatment of superficial mycoses...
  40. ncbi Pityriasis versicolor: a review of pharmacological treatment options
    Aditya K Gupta
    University of Toronto, and the Sunnybrook and Womens College Health Sciences Center Sunnybrook site, Toronto, Ontario, Canada
    Expert Opin Pharmacother 6:165-78. 2005
    ..A number of treatment options, both topical and systemic, have been shown to be effective. A critical evaluation of treatment options is presented...
  41. ncbi A phase I/II randomized, double-blind, placebo-controlled, dose-ranging study evaluating the efficacy, safety and pharmacokinetics of ravuconazole in the treatment of onychomycosis
    A K Gupta
    Division of Dermatology, Sunnybrook and Women s College Health Science Centre, University of Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 19:437-43. 2005
    ..To determine the effectiveness and safety of ravuconazole in the treatment of toenail onychomycosis...
  42. ncbi Onychomycosis therapy: past, present, future
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Canada
    J Drugs Dermatol 9:1109-13. 2010
    ..Research in these fields is preliminary, and the impact these methods may have on the future of onychomycosis remains to be seen...
  43. ncbi Tinea capitis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Canada
    Med Mycol 38:255-87. 2000
    ..Both griseofulvin and the newer antimycotics have a favorable adverse-effect profile and are associated with high compliance...
  44. ncbi Epidemiology and prevalence of onychomycosis in HIV-positive individuals
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Int J Dermatol 39:746-53. 2000
    ....
  45. ncbi Itraconazole pulse therapy is effective in the treatment of Majocchi's granuloma: a clinical and pharmacokinetic evaluation and implications for possible effectiveness in tinea capitis
    A K Gupta
    Department of Dermatology, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Clin Exp Dermatol 23:103-8. 1998
    ..These data suggest that itraconazole pulse therapy should be effective in the treatment of tinea capitis...
  46. ncbi Onychomycosis in children: prevalence and management
    A K Gupta
    Sunnybrook Health Science Center, Division of Dermatology, University of Toronto, Ontario, Canada
    Pediatr Dermatol 15:464-71. 1998
    ..The data suggest that the new oral antifungal agents have a role in the treatment of onychomycosis in children. Further experience will help us better position these drugs when evaluating the management of onychomycosis in children...
  47. ncbi Itraconazole oral solution for the treatment of onychomycosis
    A K Gupta
    Sunnybrook Health Science Center, Division of Dermatology, University of Toronto, Ontario, Canada
    Pediatr Dermatol 15:472-4. 1998
    ..Both patients were clinically and mycologically cured with no adverse effects. Itraconazole oral solution (3 mg/kg/day) given as pulse therapy may be a consideration in the treatment of onychomycosis in some children...
  48. ncbi Tinea capitis: an overview with emphasis on management
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada
    Pediatr Dermatol 16:171-89. 1999
    ..Adjunctive therapies may help decrease the risk of infection to other individuals. Appropriate measures should be taken to reduce the possibility of reinfection...
  49. ncbi The prevalence and management of onychomycosis in diabetic patients
    A K Gupta
    University of Toronto, Toronto, Canada
    Eur J Dermatol 10:379-84. 2000
    ..An ideal antifungal agent should combine a broad spectrum of activity with good efficacy and a favorable safety profile...
  50. ncbi Once weekly fluconazole is effective in children in the treatment of tinea capitis: a prospective, multicentre study
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens College Health Sciences Center Sunnybrook site, University of Toronto, Toronto, Canada
    Br J Dermatol 142:965-8. 2000
    ..9%) of 17 patients; this was asymptomatic, and reversible. No patient discontinued therapy. The data suggest that once weekly fluconazole dosing is effective, safe and associated with high compliance when used to treat tinea capitis...
  51. ncbi Drug interactions with itraconazole, fluconazole, and terbinafine and their management
    A K Gupta
    Division of Dermatology, Department of Medicine, University of Toronto, London, Ontario, N6K 1L6, Canada
    J Am Acad Dermatol 41:237-49. 1999
    ..In the case of contraindicated drugs, it may be possible to use an alternative agent...
  52. ncbi Combined distal and lateral subungual and white superficial onychomycosis in the toenails
    A K Gupta
    Department of Medicine, Sunnybrook Health Sciences Center and the University of Toronto, and the Ontario Ministry of Health, Laboratory Services Branch and Department of Laboratory Medicine and Pathology, University of Toronto
    J Am Acad Dermatol 41:938-44. 1999
    ..In the literature there is infrequent discussion about 2 types of onychomycosis present in the toenails of the same individual...
  53. ncbi Intermittent short duration therapy with fluconazole is effective for tinea capitis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto N6K 1L6, Canada
    Br J Dermatol 141:304-6. 1999
    ..This regimen appears to be effective and safe, and is associated with high compliance. The preliminary results of the investigation need to be evaluated in a larger sample of patients, and in tinea capitis caused by zoophilic species...
  54. ncbi Management of onychomycosis in children
    A K Gupta
    Division of Dermatology, University of Toronto Faculty of Medicine, Ontario, Canada
    Postgrad Med . 1999
    ..Terbinafine (continuous) or fluconazole (intermittent) regimens are other treatment options. It is important to take steps to reduce the risk of reinfection and to treat tinea pedis at an early stage...
  55. ncbi The new oral antifungal agents for onychomycosis of the toenails
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Canada
    J Eur Acad Dermatol Venereol 13:1-13. 1999
    ..To review the use of the new oral antifungal agents, itraconazole, terbinafine and fluconazole for the treatment of onychomycosis of the toenails...
  56. ncbi Ciclopirox 8% nail lacquer in the treatment of onychomycosis of the toenails in the United States
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, Toronto, Ontario, Canada
    J Am Podiatr Med Assoc 90:495-501. 2000
    ..Ciclopirox nail lacquer may also have potential for use in combination or adjunctive therapy. Further studies will help to better position this agent for the treatment of this widespread podiatric condition...
  57. ncbi Ciclopirox nail lacquer and podiatric practice
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, Toronto, Ontario, Canada
    J Am Podiatr Med Assoc 90:502-7. 2000
    ....
  58. ncbi An overview of topical antifungal therapy in dermatomycoses. A North American perspective
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Drugs 55:645-74. 1998
    ..For tinea pedis the most common treatment duration is 4 to 6 weeks...
  59. ncbi A questionnaire study on the management of onychomycosis: a Canadian perspective
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada
    Int J Dermatol 37:457-60. 1998
    ..Onychomycosis of the toenails is a condition that responds poorly to griseofulvin. The introduction of terbinafine in Canada in May 1993 resulted in a marked shift in the choice of treatment for pedal onychomycosis...
  60. ncbi Efficacy of itraconazole, terbinafine, fluconazole, griseofulvin and ketoconazole in the treatment of Scopulariopsis brevicaulis causing onychomycosis of the toes
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, and University of Toronto, Ont, Canada
    Dermatology 202:235-8. 2001
    ..Scopulariopsis brevicaulis is a common non-dermatophyte mould that can cause onychomycosis...
  61. ncbi Utility of inoculum counting (Walshe and English criteria) in clinical diagnosis of onychomycosis caused by nondermatophytic filamentous fungi
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens College Health Sciences Center, Sunnybrook, Ontario, Canada
    J Clin Microbiol 39:2115-21. 2001
    ..It may, nonetheless, provide useful information both to the physician and to the laboratory, and it may be especially valuable when the patient does not present for follow-up sampling...
  62. ncbi Single-blind, randomized, prospective study of sequential itraconazole and terbinafine pulse compared with terbinafine pulse for the treatment of toenail onychomycosis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    J Am Acad Dermatol 44:485-91. 2001
    ..Efficacy and safety of sequential pulse therapy with itraconazole and terbinafine were compared with pulse terbinafine alone in the treatment of toenail onychomycosis...
  63. ncbi Increased incidence of Trichophyton tonsurans tinea capitis in Ontario, Canada between 1985 and 1996
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Toronto, Ontario, Canada
    Med Mycol 36:55-60. 1998
    ..This should provide guidance regarding where to concentrate health resources and deliver patient/parent education to combat this epidemic of tinea capitis...
  64. ncbi Factors that may affect the response of onychomycosis to oral antifungal therapy
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada
    Australas J Dermatol 39:222-4. 1998
    ..Possible explanations for this may be grouped into categories, including: (i) patient characteristics; (ii) organisms causing or associated with the nail infection; (iii) nail characteristics; and (iv) local diseases involving the nail...
  65. ncbi In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook Site, and the University of Toronto, Toronto, ON, Canada
    Br J Dermatol 149:296-305. 2003
    ....
  66. ncbi The implications and management of drug interactions with itraconazole, fluconazole and terbinafine
    N Shear
    Departments of Medicine and Pharmacology, University of Toronto, Canada
    Dermatology 201:196-203. 2000
    ..An improved understanding of the drug interaction processes and appropriate control measures mean that the high benefit-to-risk ratio of these medications can be maintained...
  67. ncbi Fast and sensitive detection of Trichophyton rubrum DNA from the nail samples of patients with onychomycosis by a double-round polymerase chain reaction-based assay
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and the University of Toronto, Toronto, Ontario, Canada
    Br J Dermatol 157:698-703. 2007
    ..Trichophyton rubrum is one of the most frequently isolated pathogens in onychomycosis. Isolation of T. rubrum from nail samples by traditional methods is time-consuming and has a high false-negative rate of detection...
  68. ncbi Hypersensitivity syndrome reaction to oral terbinafine
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada
    Australas J Dermatol 39:171-2. 1998
    ..Prompt recognition and determination of the extent of systemic involvement is important for the proper management of the patient...
  69. ncbi Update on the safety of itraconazole pulse therapy in onychomycosis and dermatomycoses
    A Gupta
    Department of Medicine, University of Toronto, Toronto, Canada
    Eur J Dermatol 11:6-10. 2001
    ..Adverse events are generally mild and transient. Furthermore, a dose increase to 400 mg in the pulse regimen has had no adverse impact on safety...
  70. ncbi Cumulative meta-analysis of systemic antifungal agents for the treatment of onychomycosis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Br J Dermatol 150:537-44. 2004
    ..Onychomycosis is a common nail disease that is often chronic, difficult to eradicate, and has a tendency to recur. The most common oral therapies for dermatophyte toenail onychomycosis include terbinafine, itraconazole and fluconazole...
  71. ncbi Itraconazole oral solution for the treatment of tinea capitis using the pulse regimen
    A K Gupta
    Department of Dermatology, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Cutis 64:192-4. 1999
    ..The availability of the oral solution will enable more young children to be considered for treatment of tinea capitis with itraconazole than was possible when only tablets or capsules were available...
  72. ncbi Itraconazole and terbinafine treatment of some nondermatophyte molds causing onychomycosis of the toes and a review of the literature
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 5:206-10. 2001
    ..Onychomycosis may be caused by dermatophytes (which form the majority of organisms), Candida species, and nondermatophyte molds...
  73. ncbi Ciclopirox shampoo for treating seborrheic dermatitis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Science Centre (Sunnbrook site) and University of Toronto, Toronto, Canada
    Skin Therapy Lett 9:4-5. 2004
    ..This agent has been shown to be an effective and safe treatment for seborrheic dermatitis of the scalp...
  74. ncbi Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Toronto, Canada
    Br J Dermatol 139:665-71. 1998
    ..Predisposing factors include increasing age, male gender, family history of onychomycosis, concurrent intake of immunosuppressive agents and peripheral vascular disease...
  75. ncbi Onychomycosis associated with Onychocola canadensis: ten case reports and a review of the literature
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Ontario, Canada
    J Am Acad Dermatol 39:410-7. 1998
    ..The slow growth rate of O canadensis and lack of resemblance to any other known nail-infecting fungus may have delayed its discovery. We are aware of 23 mycologically confirmed cases of O canadensis in the literature...
  76. ncbi Onychomycosis: strategies to reduce failure and recurrence
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Ontario, Canada
    Cutis 62:189-91. 1998
    ..We review here some instances in which this is appropriate, as well as strategies to reduce recurrence of onychomycosis...
  77. ncbi Prescribing practices for seborrheic dermatitis vary with the physician's specialty: implications for clinical practice
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook Site, University of Toronto, Canada
    J Dermatolog Treat 15:208-13. 2004
    ....
  78. ncbi In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species
    A K Gupta
    Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Canada
    Med Mycol 43:179-85. 2005
    ....
  79. ncbi Pharmacoeconomic analysis of oral antifungal therapies used to treat dermatophyte onychomycosis of the toenails. A US analysis
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Pharmacoeconomics 13:243-56. 1998
    ..62. In conclusion, in this analysis, itraconazole (pulse) and terbinafine were the most cost-effective therapies for dermatophyte onychomycosis of the toenails, both being substantially more cost effective than griseofulvin...
  80. ncbi Molecular differentiation of seven Malassezia species
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 38:1869-75. 2000
    ..pachydermatis. This specific amplification may facilitate the rapid identification of this organism...
  81. ncbi The efficacy and safety of terbinafine in children
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Eur Acad Dermatol Venereol 17:627-40. 2003
    ..The adverse events profile for children is similar to that in adults with few adverse effects associated with its use. The evidence favours the use of terbinafine in the treatment of superficial infections in children...
  82. ncbi The use of itraconazole to treat cutaneous fungal infections in children
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Canada
    Dermatology 199:248-52. 1999
    ..There is relatively limited data regarding the use of the newer oral antifungal agents, e.g. itraconazole, in the treatment of these mycoses in children...
  83. ncbi Itraconazole pulse therapy for the treatment of Candida onychomycosis
    A K Gupta
    Department of Medicine, Sunnybrook and Womens' College Health Sciences Center, University of Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 15:112-5. 2001
    ..In conclusion, itraconazole pulse therapy is an effective and safe treatment for both finger and toe onychomycosis associated with Candida...
  84. ncbi Therapeutic options for the treatment of tinea capitis caused by Trichophyton species: griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazole
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, Toronto, Canada
    Pediatr Dermatol 18:433-8. 2001
    ..Each of the agents has a favorable adverse-effects profile...
  85. ncbi Single-blind, randomized, prospective study on terbinafine and itraconazole for treatment of dermatophyte toenail onychomycosis in the elderly
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    J Am Acad Dermatol 44:479-84. 2001
    ..Although comparative studies have been performed evaluating the efficacy of these 2 agents in adults, no such studies have been reported specifically in the elderly subset...
  86. ncbi Fungicidal activities of commonly used disinfectants and antifungal pharmaceutical spray preparations against clinical strains of Aspergillus and Candida species
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Med Mycol 40:201-8. 2002
    ..ochraceus conidia and an onset of fungicidal effect on C. parapsilosis yeast cells. Terbinafine was only moderately effective against C. albicans and was completely ineffective against C. krusei...
  87. ncbi Quantitative culture of Malassezia species from different body sites of individuals with or without dermatoses
    A K Gupta
    Department of Medicine, Women s College Hospital, University of Toronto, Canada
    Med Mycol 39:243-51. 2001
    ..Among normal individuals and for patients with AD and PV, M. sympodialis was significantly more likely to affect the forehead than the legs...
  88. ncbi Pimecrolimus: a review
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Eur Acad Dermatol Venereol 17:493-503. 2003
    ..It has been shown to be effective in atopic and allergic contact dermatitis, with a favorable adverse-effects profile, which includes little effect on the systemic immune response...
  89. ncbi Onychomycosis in the elderly
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Ontario, Canada
    Drugs Aging 16:397-407. 2000
    ..Once cure has been achieved, it is important to counsel patients on the strategies of reducing recurrence of disease...
  90. ncbi Open-label study to evaluate the healing rate and safety of the Profore Extra Four-Layer Bandage System in patients with venous leg ulceration
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens Health Sciences Centre Sunnybrook Site and the University of Toronto Medical School, Toronto, Ontario, Canada
    J Cutan Med Surg 4:8-11. 2000
    ..Venous ulcers are increasing in prevalence, especially since these are observed more frequently in the elderly, and the number of individuals in this age group is becoming a larger portion of the population...
  91. ncbi A risk-benefit assessment of the newer oral antifungal agents used to treat onychomycosis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s Health Sciences Center, University of Toronto Medical School, Canada
    Drug Saf 22:33-52. 2000
    ..The newer antifungal agents are generally well tolerated with drug interactions that are usually predictable...
  92. ncbi Detection of xanthomegnin in epidermal materials infected with Trichophyton rubrum
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Ontario, Canada
    J Invest Dermatol 115:901-5. 2000
    ..Xanthomegnin was not detected in uninfected nails. These results show that patients with Trichophyton rubrum infections may be exposed to xanthomegnin, although the consequences of such an exposure are not currently known...
  93. ncbi Epidemiology of Malassezia yeasts associated with pityriasis versicolor in Ontario, Canada
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Ontario, Canada
    Med Mycol 39:199-206. 2001
    ....
  94. ncbi The use of an intermittent terbinafine regimen for the treatment of dermatophyte toenail onychomycosis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and the University of Toronto, Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 23:256-62. 2009
    ..To compare the efficacy and safety of intermittent terbinafine with standard courses of terbinafine and itraconazole for dermatophyte toenail onychomycosis...
  95. ncbi Itraconazole oral solution for the treatment of tinea capitis
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Br J Dermatol 139:104-6. 1998
    ..It remains to be seen whether itraconazole oral solution will become a practical alternative to the antifungal agents available in a liquid preparation for the treatment of tinea capitis...
  96. ncbi The epidemiology of onychomycosis: possible role of smoking and peripheral arterial disease
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, and University of Toronto, Canada
    J Eur Acad Dermatol Venereol 14:466-9. 2000
    ..In our clinical practice we have observed that smokers and individuals with peripheral arterial disease may have an increased prevalence of onychomycosis compared to normal individuals...
  97. ncbi In vitro susceptibility of the seven Malassezia species to ketoconazole, voriconazole, itraconazole and terbinafine
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Canada
    Br J Dermatol 142:758-65. 2000
    ..M. furfur strains tested with terbinafine ranged from highly susceptible to relatively resistant. Correct identification of Malassezia species could facilitate selection of appropriate antifungal therapy...
  98. ncbi Dabigatran versus warfarin in patients with atrial fibrillation
    Stuart J Connolly
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    N Engl J Med 361:1139-51. 2009
    ..Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases the risk of hemorrhage and is difficult to use. Dabigatran is a new oral direct thrombin inhibitor...
  99. ncbi Management of diaper dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center Sunnybrook site, London, Ontario, Canada
    Int J Dermatol 43:830-4. 2004
  100. ncbi Evaluation of in vitro resistance in patients with onychomycosis who fail antifungal therapy
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Dermatology 207:375-80. 2003
    ..However, relatively little research has been published concerning the resistance of dermatophyte species...
  101. ncbi Systematic review of rosacea treatments
    Esther J Van Zuuren
    Department of Dermatology B1 Q, Leiden University Medical Center, The Netherlands
    J Am Acad Dermatol 56:107-15. 2007
    ..Rosacea is a common chronic skin and ocular condition. It is unclear which treatments are most effective. We have conducted a Cochrane review of rosacea therapies. This article is a distillation of that work...