S M Dursun

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. ncbi High-dose vitamin E plus vitamin B6 treatment of risperidone-related neuroleptic malignant syndrome
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 12:220-1. 1998
  2. ncbi The 'dalhousie serotonin cocktail' for treatment-resistant major depressive disorder
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 15:136-8. 2001
  3. ncbi Nefazodone treatment of dysthymic disorder an open, long-term, prospective pilot study
    Serdar M Dursun
    Psychopharmacology Research Unit, Department of Psychiatry, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 26:671-6. 2002
  4. ncbi An exploratory approach to the serotonergic hypothesis of depression: bridging the synaptic gap
    S M Dursun
    Psychopharmacology Unit, Department of Psychiatry, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Abbie J Lane Building, 4th Floor Suite 4083, Halifax, Nova Scotia B3H 2E2, Canada
    Med Hypotheses 56:235-43. 2001
  5. ncbi The effects of antipsychotic medication on saccadic eye movement abnormalities in Huntington's disease
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    Prog Neuropsychopharmacol Biol Psychiatry 24:889-96. 2000
  6. ncbi Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, England
    J Psychiatry Neurosci 25:347-52. 2000
  7. ncbi Antisaccade eye movement abnormalities in Tourette syndrome: evidence for cortico-striatal network dysfunction?
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    J Psychopharmacol 14:37-9. 2000
  8. ncbi The effects of clozapine on levels of total cholesterol and related lipids in serum of patients with schizophrenia: a prospective study
    S M Dursun
    Department of Psychiatry, University of Leicester, UK
    J Psychiatry Neurosci 24:453-5. 1999
  9. ncbi Effects of typical antipsychotic drugs and risperidone on the quality of sleep in patients with schizophrenia: a pilot study
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    J Psychiatry Neurosci 24:333-7. 1999
  10. ncbi Effects of amphetamine on saccadic eye movements in man: possible relevance to schizophrenia?
    S M Dursun
    Department of Psychiatry, University of Leicester, UK
    J Psychopharmacol 13:245-7. 1999

Collaborators

Detail Information

Publications16

  1. ncbi High-dose vitamin E plus vitamin B6 treatment of risperidone-related neuroleptic malignant syndrome
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 12:220-1. 1998
    ..We present a case of a 74-year-old patient with schizoaffective disorder, who developed risperidone-related neuroleptic malignant syndrome. This patient responded satisfactorily to the supportive management and vit E plus vit B6...
  2. ncbi The 'dalhousie serotonin cocktail' for treatment-resistant major depressive disorder
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 15:136-8. 2001
    ..Due to limited sample size, an open design and an 'unusually' high successful efficacy rate of this preliminary study, controlled studies are required to confirm the efficacy of this treatment strategy...
  3. ncbi Nefazodone treatment of dysthymic disorder an open, long-term, prospective pilot study
    Serdar M Dursun
    Psychopharmacology Research Unit, Department of Psychiatry, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 26:671-6. 2002
    ....
  4. ncbi An exploratory approach to the serotonergic hypothesis of depression: bridging the synaptic gap
    S M Dursun
    Psychopharmacology Unit, Department of Psychiatry, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Abbie J Lane Building, 4th Floor Suite 4083, Halifax, Nova Scotia B3H 2E2, Canada
    Med Hypotheses 56:235-43. 2001
    ..e. pre and post synaptic serotonergic symptoms are affected. Furthermore, we will also be providing the implications of this approach for normal treatments for depressive disorder...
  5. ncbi The effects of antipsychotic medication on saccadic eye movement abnormalities in Huntington's disease
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    Prog Neuropsychopharmacol Biol Psychiatry 24:889-96. 2000
    ....
  6. ncbi Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, England
    J Psychiatry Neurosci 25:347-52. 2000
    ....
  7. ncbi Antisaccade eye movement abnormalities in Tourette syndrome: evidence for cortico-striatal network dysfunction?
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    J Psychopharmacol 14:37-9. 2000
    ..3 for the Tourette syndrome group and 11.9+/-6.4 for controls, respectively. These significant results may further support dysfunction of the frontocortico-striatal network in Tourette syndrome...
  8. ncbi The effects of clozapine on levels of total cholesterol and related lipids in serum of patients with schizophrenia: a prospective study
    S M Dursun
    Department of Psychiatry, University of Leicester, UK
    J Psychiatry Neurosci 24:453-5. 1999
    ..To investigate the effects of 12 weeks of clozapine treatment on levels of cholesterol and related lipids in patients with schizophrenia...
  9. ncbi Effects of typical antipsychotic drugs and risperidone on the quality of sleep in patients with schizophrenia: a pilot study
    S M Dursun
    Department of Psychiatry, Faculty of Medicine, University of Leicester, UK
    J Psychiatry Neurosci 24:333-7. 1999
    ..To investigate the effects of a newer antipsychotic drug, risperidone (a potent serotonin 5-HT2A/2C and dopamine D2-receptor blocker), on the quantity and quality of sleep in patients with schizophrenia...
  10. ncbi Effects of amphetamine on saccadic eye movements in man: possible relevance to schizophrenia?
    S M Dursun
    Department of Psychiatry, University of Leicester, UK
    J Psychopharmacol 13:245-7. 1999
    ..These results may suggest that increased error rates and latencies during antisaccade tasks may be due to increased dopamine transmission, which is similar to the findings in schizophrenia...
  11. ncbi Olanzapine for patients with treatment-resistant schizophrenia: a naturalistic case-series outcome study
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia
    Can J Psychiatry 44:701-4. 1999
    ..This prospective, consecutive case-series outcome investigation evaluates the effectiveness of olanzapine in 16 patients with treatment-resistant schizophrenia...
  12. ncbi Augmenting antipsychotic treatment with lamotrigine or topiramate in patients with treatment-resistant schizophrenia: a naturalistic case-series outcome study
    S M Dursun
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 15:297-301. 2001
    ....
  13. ncbi Maintained improvement with minocycline of a patient with advanced Huntington's disease
    E M Denovan-Wright
    Department of Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Psychopharmacol 16:393-4. 2002
    ..By contrast, this present result suggests that minocycline may benefit those with advanced Huntington's disease and can be used safely in these patients...
  14. ncbi Lack of phencyclidine-induced effects in mice with reduced neuronal nitric oxide synthase
    D C Bird
    Dalhousie University, Department of Pharmacology, Halifax, Nova Scotia, Canada
    Psychopharmacology (Berl) 155:299-309. 2001
    ..Furthermore, we show that an intact nNOS system is necessary to obtain PCP-induced effects. This may implicate nNOS as a viable drug target in the treatment of schizophrenia...
  15. ncbi Effects of antidepressant treatments on first-ECT seizure duration in depression
    S M Dursun
    Department of Psychiatry, University of Leicester, UK
    Prog Neuropsychopharmacol Biol Psychiatry 25:437-43. 2001
    ..4. There was no significant difference between electrical charge applied to either group. Between the TCA and SSRI group the seizure duration was not significantly different: 33.2 seconds and 31.4 seconds respectively...
  16. ncbi A Canadian multicenter trial assessing memory and executive functions in patients with schizophrenia spectrum disorders treated with olanzapine
    Emmanuel Stip
    Centre de Recherche Fernand Seguin, 7331 rue Hochelaga, Montreal, Quebec, Canada H1N 3V2
    J Clin Psychopharmacol 23:400-4. 2003
    ..After switching to olanzapine, there was a statistically significant improvement of cognitive function in the 3 main domains tested and no significant worsening of any memory or executive function measure...