Research Topics
Genomes and GenesSpecies | Nadir ChabaneSummaryCountry: Canada Publications
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Detail Information
Publications
Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritisNadir Chabane
Osteoarthritis Research Unit, Research Centre of the University of Montreal Hospital Center, Notre Dame Hospital, Montreal, Quebec, Canada
Arthritis Res Ther 11:R44. 2009....
Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1Nadia Zayed
Osteoarthritis Research Unit, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, Montreal, Quebec, Canada
J Rheumatol 38:492-502. 2011..We examined the effects of valproic acid (VA), a histone deacetylase inhibitor, on interleukin 1ß (IL-1ß)-induced mPGES-1 expression in human chondrocytes, and evaluated the roles of Egr-1 and NAB1 in these effects...
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2Nadia Zayed
Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, and University of Montreal, Montreal, Quebec, Canada
Arthritis Rheum 58:3530-40. 2008..To investigate the effects of prostaglandin D2 (PGD2) on interleukin-1beta (IL-1beta)-induced matrix metalloproteinase 1 (MMP-1) and MMP-13 expression in human chondrocytes and the signaling pathways involved in these effects...
Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytesFatima Ezzahra El Mansouri
Research Centre of the University of Montreal Hospital Centre, Notre Dame Hospital, and University of Montreal, Montreal, Quebec, Canada
Arthritis Rheum 63:168-79. 2011..To investigate the role of histone H3 lysine 4 (H3K4) methylation in interleukin-1? (IL-1?)-induced cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS) expression in human osteoarthritic (OA) chondrocytes...
Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilageNadia Zayed
Osteoarthritis Research Unit, Research Centre of the University of Montreal Hospital Center, Notre Dame Hospital, Montreal, QC, Canada
Arthritis Res Ther 10:R146. 2008....
HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activityNadir Chabane
Osteoarthritis Research Unit, Centre Hospitalier de l Universite de Montreal CHUM, Department of Medicine, Notre Dame Hospital, University of Montreal, 1560 Sherbrooke Street East, Montreal, Quebec, Canada H2L 4M1
J Cell Biochem 106:453-63. 2009..Together these data indicate that HDAC4 contributes to transcriptional induction of mPGES-1 by IL-1 through a mechanism involving up-regulation of Egr-1 transcriptional activity...
