Evan Wood

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. ncbi An external evaluation of a peer-run "unsanctioned" syringe exchange program
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada BC V6Z 1Y6
    J Urban Health 80:455-64. 2003
  2. ncbi Higher baseline levels of plasma human immunodeficiency virus type 1 RNA are associated with increased mortality after initiation of triple-drug antiretroviral therapy
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
    J Infect Dis 188:1421-5. 2003
  3. ncbi Requiring help injecting as a risk factor for HIV infection in the Vancouver epidemic: implications for HIV prevention
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver
    Can J Public Health 94:355-9. 2003
  4. ncbi Sociodemographic disparities in access to addiction treatment among a cohort of Vancouver injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
    Subst Use Misuse 40:1153-67. 2005
  5. ncbi Adherence and plasma HIV RNA responses to highly active antiretroviral therapy among HIV-1 infected injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC
    CMAJ 169:656-61. 2003
  6. ncbi Prevalence and correlates of untreated human immunodeficiency virus type 1 infection among persons who have died in the era of modern antiretroviral therapy
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    J Infect Dis 188:1164-70. 2003
  7. ncbi Inability to access addiction treatment and risk of HIV infection among injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver and Department of Health Care and Epidemiology Faculty of Medicine, University of British Columbia, Canada
    J Acquir Immune Defic Syndr 36:750-4. 2004
  8. ncbi Adherence to antiretroviral therapy and CD4 T-cell count responses among HIV-infected injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Antivir Ther 9:229-35. 2004
  9. ncbi Smoking of crack cocaine as a risk factor for HIV infection among people who use injection drugs
    Kora deBeck
    British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Vancouver, BC
    CMAJ 181:585-9. 2009
  10. ncbi Structural factors associated with an increased risk of HIV and sexually transmitted infection transmission among street-involved youth
    Brandon D L Marshall
    British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    BMC Public Health 9:7. 2009

Detail Information

Publications97

  1. ncbi An external evaluation of a peer-run "unsanctioned" syringe exchange program
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada BC V6Z 1Y6
    J Urban Health 80:455-64. 2003
    ..The findings also suggest that other forms of syringe-exchange programs should consider the benefits of offering fixed site nighttime service...
  2. ncbi Higher baseline levels of plasma human immunodeficiency virus type 1 RNA are associated with increased mortality after initiation of triple-drug antiretroviral therapy
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
    J Infect Dis 188:1421-5. 2003
    ..71; 95% confidence interval, 1.08-2.70; P=.023). If appropriately confirmed, these findings have important implications for the development of therapeutic guidelines...
  3. ncbi Requiring help injecting as a risk factor for HIV infection in the Vancouver epidemic: implications for HIV prevention
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver
    Can J Public Health 94:355-9. 2003
    ..This risk factor remains poorly understood. The present study investigates this risk factor among Vancouver IDUs...
  4. ncbi Sociodemographic disparities in access to addiction treatment among a cohort of Vancouver injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
    Subst Use Misuse 40:1153-67. 2005
    ..These findings demonstrate low levels of addiction treatment among Vancouver IDUs and suggest that programs may need to be targeted towards specific populations with poor access...
  5. ncbi Adherence and plasma HIV RNA responses to highly active antiretroviral therapy among HIV-1 infected injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC
    CMAJ 169:656-61. 2003
    ..We evaluated virological responses to HAART among HIV-1 infected patients who were injection drug users (IDUs) in a population-based setting where HIV/AIDS care is delivered free of charge...
  6. ncbi Prevalence and correlates of untreated human immunodeficiency virus type 1 infection among persons who have died in the era of modern antiretroviral therapy
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    J Infect Dis 188:1164-70. 2003
    ..5%) received antiretroviral medication >or=75% of the time during their first year receiving therapy. The data demonstrate the need for novel interventions to expand HIV care to specific populations...
  7. ncbi Inability to access addiction treatment and risk of HIV infection among injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver and Department of Health Care and Epidemiology Faculty of Medicine, University of British Columbia, Canada
    J Acquir Immune Defic Syndr 36:750-4. 2004
    ....
  8. ncbi Adherence to antiretroviral therapy and CD4 T-cell count responses among HIV-infected injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Antivir Ther 9:229-35. 2004
    ....
  9. ncbi Smoking of crack cocaine as a risk factor for HIV infection among people who use injection drugs
    Kora deBeck
    British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Vancouver, BC
    CMAJ 181:585-9. 2009
    ..Given the increasing use of crack cocaine, we sought to examine whether use of this illicit drug has become a risk factor for HIV infection...
  10. ncbi Structural factors associated with an increased risk of HIV and sexually transmitted infection transmission among street-involved youth
    Brandon D L Marshall
    British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    BMC Public Health 9:7. 2009
    ....
  11. ncbi Incarceration experiences in a cohort of active injection drug users
    M J Milloy
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    Drug Alcohol Rev 27:693-9. 2008
    ..Incarceration has been associated with a number of health-related harms among injection drug users (IDU). However, little is known about the prevalence and correlates of incarceration among community-based samples of IDU...
  12. ncbi Syringe sharing and HIV incidence among injection drug users and increased access to sterile syringes
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, Department of Medicine, University of British Columbia, Vancouver, Canada
    Am J Public Health 100:1449-53. 2010
    ..We assessed the effects of syringe exchange program (SEP) policy on rates of HIV risk behavior and HIV incidence among injection drug users...
  13. ncbi Changes in injecting practices associated with the use of a medically supervised safer injection facility
    Jo Anne Stoltz
    Clinical Activities, British Columbia Centre of Excellence in HIV AIDS, University of British Columbia, Vancouver, Canada
    J Public Health (Oxf) 29:35-9. 2007
    ....
  14. ncbi Potential uptake and correlates of willingness to use a supervised smoking facility for noninjection illicit drug use
    Courtney L C Collins
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada V6Z 1Y6
    J Urban Health 82:276-84. 2005
    ..Although the impact of SSFs in North America can only be quantified by scientific evaluation, these data indicate a potential for public health and community benefits if SSFs were to become available...
  15. ncbi Risk factors for developing a cutaneous injection-related infection among injection drug users: a cohort study
    Elisa Lloyd-Smith
    BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    BMC Public Health 8:405. 2008
    ..However, risk factors for CIRI have not been well described in the literature. We sought to characterize the risk factors for current CIRI among individuals who use North America's first supervised injection facility (SIF)...
  16. ncbi Antiretroviral adherence and HIV treatment outcomes among HIV/HCV co-infected injection drug users: the role of methadone maintenance therapy
    Anita Palepu
    Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, University of British Columbia, BC, Canada
    Drug Alcohol Depend 84:188-94. 2006
    ..We examined the association of methadone maintenance therapy (MMT) with highly active antiretroviral therapy (HAART) adherence and HIV treatment outcomes among a cohort of HIV/HCV co-infected injection drug users (IDUs)...
  17. ncbi Characteristics of injection drug users who participate in drug dealing: implications for drug policy
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
    J Psychoactive Drugs 40:147-52. 2008
    ..These findings suggest that elements of "balanced" drug policies may undermine each other and indicate the need for alternative interventions...
  18. ncbi Effects of police confiscation of illicit drugs and syringes among injection drug users in Vancouver
    Daniel Werb
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    Int J Drug Policy 19:332-8. 2008
    ..Drug market policing has been associated with various harms among injection drug users (IDU). However, little is known about instances in which drugs and injecting equipment are confiscated from IDU in the absence of a formal arrest...
  19. ncbi Total lymphocyte count as a possible surrogate of CD4 cell count to prioritize eligibility for antiretroviral therapy among HIV-infected individuals in resource-limited settings
    Richard Bedell
    Centre for Excellence in HIV/AIDS, University of British Columbia, Vancouver, British Columbia, Canada
    Antivir Ther 8:379-84. 2003
    ..Our results suggest that, if appropriately validated, judicious application of total lymphocyte counts could overcome one of the practical obstacles to more widespread provision of antiretroviral therapy in resource-poor settings...
  20. ncbi Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy
    Viviane D Lima
    BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    AIDS 21:685-92. 2007
    ..To characterize the temporal changes in mortality and life expectancy among HIV-positive individuals initiating antiretroviral therapy in British Columbia, Canada, from 1993 to 2004...
  21. ncbi Burden of HIV infection among aboriginal injection drug users in Vancouver, British Columbia
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
    Am J Public Health 98:515-9. 2008
    ..We sought to examine whether there were differential rates of HIV incidence among Aboriginal and non-Aboriginal injection drug users in a Canadian setting...
  22. ncbi Non-fatal overdose among a cohort of active injection drug users recruited from a supervised injection facility
    M J S Milloy
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Drug Alcohol Abuse 34:499-509. 2008
    ..Our findings indicate that a sub-population of IDU might benefit from overdose prevention interventions. Our findings refute the suggestion that the SIF may increase the likelihood of overdose...
  23. ncbi Emergence of drug resistance is associated with an increased risk of death among patients first starting HAART
    Robert S Hogg
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    PLoS Med 3:e356. 2006
    ..The objective of this study was to determine the impact of the emergence of drug-resistance mutations on survival among persons initiating HAART...
  24. ncbi Rationale to evaluate medically supervised safer smoking facilities for non-injection illicit drug users
    Courtney L C Collins
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC
    Can J Public Health 96:344-7. 2005
    ..Also relevant to this topic are interventions to prevent transition into injection drug use, and SSFs may also be evaluated as a potential strategy to address this concern...
  25. ncbi Recent incarceration independently associated with syringe sharing by injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Public Health Rep 120:150-6. 2005
    ..Few prospective studies are available on the relationship between incarceration and HIV risk among injection drug users (IDUs). The authors evaluated self-reported rates of syringe sharing and incarceration among a cohort of IDUs...
  26. ncbi Incidence and determinants of initiation into cocaine injection and correlates of frequent cocaine injectors
    Elisa Lloyd-Smith
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital 608 1081, Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    Drug Alcohol Depend 99:176-82. 2009
    ..To investigate the incidence and correlates of cocaine injection initiation and the impacts of daily cocaine injection among a cohort of injection drug users...
  27. ncbi Factors associated with willingness to participate in a heroin prescription program among injection drug users
    Cari L Miller
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
    J Opioid Manag 1:201-3. 2005
    ..These findings indicate that a clinical trial of prescribed heroin should be able to enroll an appropriate sample of drug users and properly assess the treatment potential of prescribed opiate pharmacotherapy...
  28. ncbi Factors associated with buying and selling syringes among injection drug users in a setting of one of North America's largest syringe exchange programs
    Laura M Kuyper
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
    Subst Use Misuse 41:883-99. 2006
    ..Syringe buyers were more likely to need help injecting, have difficulty finding new syringes, have binged on drugs, and have visited the SEP at least once weekly. Syringe buying most frequently occurred when the SEP was closed...
  29. ncbi Differential impact of adherence on long-term treatment response among naive HIV-infected individuals
    Viviane D Lima
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    AIDS 22:2371-80. 2008
    ....
  30. ncbi Injection drug use among street-involved youth in a Canadian setting
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, British Columbia, Canada
    BMC Public Health 9:171. 2009
    ..We undertook this study to examine the prevalence of injection drug use and associated risks among street-involved youth in Vancouver, Canada...
  31. ncbi Risks surrounding drug trade involvement among street-involved youth
    Daniel Werb
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Drug Alcohol Abuse 34:810-20. 2008
    ..The present study was therefore conducted to investigate factors associated with the street-level drug trade involvement among street-based youth...
  32. ncbi HIV risks associated with incarceration among injection drug users: implications for prison-based public health strategies
    Daniel Werb
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    J Public Health (Oxf) 30:126-32. 2008
    ..We sought to evaluate the potential impact of incarceration on HIV risk behaviour among the IDU enrolled in a prospective cohort study...
  33. ncbi Predictors of non-fatal overdose among a cohort of polysubstance-using injection drug users
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada
    Drug Alcohol Depend 87:39-45. 2007
    ..Non-fatal overdose is a major determinant of morbidity among injection drug users (IDU). We sought to evaluate factors associated with non-fatal overdose among IDU in Vancouver...
  34. ncbi Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
    BMJ 338:b1649. 2009
    ..To examine the relation between plasma HIV-1 RNA concentrations in the community and HIV incidence among injecting drug users...
  35. ncbi Incarceration and drug use patterns among a cohort of injection drug users
    Kora deBeck
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada
    Addiction 104:69-76. 2009
    ..However, the impact of incarceration on deterring drug use remains under-evaluated. We sought to explore the relationship between incarceration and patterns of drug use among people who inject drugs (IDU)...
  36. ncbi Expanding the reach of harm reduction in Thailand: experiences with a drug user-run drop-in centre
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver BC, V6Z 1Y6 Canada
    Int J Drug Policy 21:255-8. 2010
    ..In response, a drug user-led harm reduction centre opened in 2004 in an effort to expand reduction programming in Thailand...
  37. ncbi Crystal methamphetamine use associated with non-fatal overdose among a cohort of injection drug users in Vancouver
    Nadia Fairbairn
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC Canada, V6Z 146
    Public Health 122:70-8. 2008
    ..To evaluate the prevalence and correlates of non-fatal overdose among a polysubstance-using cohort of injection drug users (IDU) in Vancouver...
  38. ncbi Prevalence and correlates of cervical cancer screening among injection drug users
    Bruce McKnight
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    J Obstet Gynaecol Can 28:695-9. 2006
    ..This is reassuring, given the elevated risk of cervical cancer among this population. Interventions may be required to improve uptake of screening among older injection drug users and drug users infected with hepatitis C...
  39. ncbi Injection drug users' perceptions regarding use of a medically supervised safer injecting facility
    Steven Petrar
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver BC, Canada V6Z 1Y6
    Addict Behav 32:1088-93. 2007
    ..This study was undertaken to explore injection drug users' experiences and opinions regarding North America's first SIF in Vancouver, Canada...
  40. ncbi Frequent needle exchange use and HIV incidence in Vancouver, Canada
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Am J Med 120:172-9. 2007
    ..Opposition to needle exchange programs has been fueled by a Vancouver study showing an association between frequent program use and elevated rates of human immunodeficiency virus (HIV) infection among injection drug users...
  41. ncbi Impact of baseline viral load and adherence on survival of HIV-infected adults with baseline CD4 cell counts > or = 200 cells/microl
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 667-1081 Burrard Street, Vancouver, BC, Canada
    AIDS 20:1117-23. 2006
    ..89-1.65; P = 0.232). CONCLUSION: HIV RNA > or = 100 000 copies/ml was only associated with mortality among HIV-infected patients initiating HAART with CD4 cell counts > or= 200 cells/microl if the patients were non-adherent...
  42. ncbi Prevalence and correlates of jugular injections among injection drug users
    Zia Hoda
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Drug Alcohol Rev 27:442-6. 2008
    ..We evaluated factors associated with jugular injection among a cohort of injection drug users (IDU) in Vancouver, Canada...
  43. ncbi Difficulty accessing syringes and syringe borrowing among injection drug users in Bangkok, Thailand
    Thomas Kerr
    Urban Health Research Initiative, British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Drug Alcohol Rev 29:157-61. 2010
    ..This study was undertaken to examine risk factors for syringe borrowing among a community-recruited sample of Thai IDU...
  44. ncbi Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study
    Julio S G Montaner
    British Columbia Centre for Excellence in HIV AIDS, Providence Health Care, Vancouver, BC, Canada
    Lancet 376:532-9. 2010
    ..We aimed to estimate the association between plasma HIV-1 viral load, HAART coverage, and number of new cases of HIV in the population of a Canadian province...
  45. ncbi Social and structural barriers to housing among street-involved youth who use illicit drugs
    Andrea Krusi
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada V6Z1Y6
    Health Soc Care Community 18:282-8. 2010
    ..Our findings point to the need for housing strategies that include safe, low threshold, harm reduction focused housing options for youth who engage in illicit substance use...
  46. ncbi Elevated HIV risk behaviour among recently incarcerated injection drug users in a Canadian setting: a longitudinal analysis
    M J S Milloy
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    BMC Public Health 9:156. 2009
    ..We sought to assess the impact of incarceration on risk factors for HIV infection after release from prison in a sample of active IDU in Vancouver, Canada...
  47. ncbi Ongoing drug use and outcomes from highly active antiretroviral therapy among injection drug users in a Canadian setting
    Andrea Krusi
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Antivir Ther 15:789-96. 2010
    ..We sought to investigate the influence of drug use patterns on adherence to antiretroviral therapy and virological suppression among IDUs...
  48. ncbi Survival sex work involvement as a primary risk factor for hepatitis C virus acquisition in drug-using youths in a canadian setting
    Kate Shannon
    British Columbia Centre for Excellence in HIV AIDS, Division of AIDS, Department of Medicine, University of British Columbia, St Paul s Hospital, 608 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
    Arch Pediatr Adolesc Med 164:61-5. 2010
    ..To examine whether there were differential rates of hepatitis C virus (HCV) incidence in injecting drug-using youths who did and did not report involvement in survival sex work...
  49. ncbi Slower uptake of HIV antiretroviral therapy among Aboriginal injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    J Infect 52:233-6. 2006
    ..We examined the time to antiretroviral therapy (ART) use among antiretroviral naïve HIV infected injection drug users participating in a prospective cohort study in Vancouver, Canada...
  50. ncbi Directly observed therapy programmes for anti-retroviral treatment amongst injection drug users in Vancouver: access, adherence and outcomes
    Mark W Tyndall
    Department of Medicine, University of British Columbia, Canada
    Int J Drug Policy 18:281-7. 2007
    ..The programmes initiated in Vancouver demonstrate the positive impact that a comprehensive DOT programme can have on ARV adherence, as well as highlight the challenges that remain...
  51. ncbi Attendance, drug use patterns, and referrals made from North America's first supervised injection facility
    Mark W Tyndall
    Department of Medicine, and BC Centre for Excellence in HIV AIDS, University of British Columbia, St Paul s Hospital, 1081 Burrard Street, Vancouver, BC, Canada
    Drug Alcohol Depend 83:193-8. 2006
    ..This analysis was conducted to describe the attendance, demographic characteristics, drug use patterns, and referrals made during the first 18 months of operation...
  52. ncbi Nonadherence increases the risk of hospitalization among HIV-infected antiretroviral naive patients started on HAART
    Sarah J Fielden
    B C Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada, Department of Interdisciplinary Studies, University of British Columbia, Vancouver, British Columbia, Canada
    J Int Assoc Physicians AIDS Care (Chic) 7:238-44. 2008
    ..Methods: Analysis was based on a cohort of individuals initiating HAART between 1996 and 2001. The primary outcome was hospitalization for one or more days. Survival methods were used to assess the impact of adherence on hospitalization...
  53. ncbi Requiring help injecting independently predicts incident HIV infection among injection drug users
    Thomas Kerr
    British Columbia Centre for Excellence in HIV/AIDS, University of British Columbia, St. Paul's Hospital, Vancouver, Canada
    J Acquir Immune Defic Syndr 40:83-8. 2005
    ..79, 95% CI: 1.23-2.62) remained independent predictors of HIV seroconversion. CONCLUSIONS: These data demonstrate the need for interventions to reduce the risk of HIV infection among IDUs who require help injecting...
  54. ncbi Nonfatal overdose among a cohort of street-involved youth
    Daniel Werb
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    J Adolesc Health 42:303-6. 2008
    ..Our findings indicate that nonfatal overdose was common among street-involved youth in our setting, and was associated with various forms of drug use, including methamphetamine use...
  55. ncbi A micro-environmental intervention to reduce the harms associated with drug-related overdose: evidence from the evaluation of Vancouver's safer injection facility
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    Int J Drug Policy 18:37-45. 2007
    ..Safer injection facilities (SIFs) constitute one such intervention, although little is known about the impact of such facilities on factors that mediate risk for overdose...
  56. ncbi Changes in Canadian heroin supply coinciding with the Australian heroin shortage
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Canada
    Addiction 101:689-95. 2006
    ....
  57. ncbi Police and public health partnerships: evidence from the evaluation of Vancouver's supervised injection facility
    Kora deBeck
    British Columbia Centre for Excellence in HIV AIDS, 608 1081 Burrard Street, Vancouver, B, C, V6Z 1Y6, Canada
    Subst Abuse Treat Prev Policy 3:11. 2008
    ..Our study suggests that the SIF provides an opportunity to coordinate policing and public health efforts and thereby resolve some of the existing tensions between public order and health initiatives...
  58. ncbi Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users
    Sasha Uhlmann
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    Addiction 105:907-13. 2010
    ..We examined whether methadone maintenance therapy (MMT) increased initiation and adherence to ART among an IDU population with free health care...
  59. ncbi Severe food insecurity is associated with elevated unprotected sex among HIV-seropositive injection drug users independent of HAART use
    Kate Shannon
    BC Centre for Excellence in HIV AIDS, Department of Medicine, University of British Columbia, Vancouver, Canada
    AIDS 25:2037-42. 2011
    ..To our knowledge, this study is the first to longitudinally evaluate the relationship between food insecurity and unprotected sex among HIV-seropositive people who inject drugs [injection drug users (IDUs)] both on and not on HAART...
  60. ncbi HIV and hepatitis C outbreaks among high-risk youth in Vancouver demands a public health response
    Cari L Miller
    British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC
    Can J Public Health 96:107-8. 2005
    ..Without focussing such resources, further HIV and HCV infections and subsequent higher health care costs appear imminent...
  61. ncbi Factors associated with methadone maintenance therapy use among a cohort of polysubstance using injection drug users in Vancouver
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
    Drug Alcohol Depend 80:329-35. 2005
    ..While the use of MMT was associated with reductions in heroin use and HIV risk behavior, barriers to Aboriginal IDUs were evident, and the association with increased crack cocaine use deserves further study...
  62. ncbi Impact of neighborhood-level socioeconomic status on HIV disease progression in a universal health care setting
    Ruth Joy
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    J Acquir Immune Defic Syndr 47:500-5. 2008
    ....
  63. ncbi Is there a baseline CD4 cell count that precludes a survival response to modern antiretroviral therapy?
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
    AIDS 17:711-20. 2003
    ..Our results indicate that the current emphasis of therapeutic guidelines on initiating therapy at CD4 cell counts above 200 x 106 cells/l should be re-examined...
  64. ncbi "Discordant" increases in CD4 cell count relative to plasma viral load in a closely followed cohort of patients initiating antiretroviral therapy
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
    J Acquir Immune Defic Syndr 30:159-66. 2002
    ..Similarities between transient and full virologic responders also appear to be time limited and are often associated with greater cumulative use of antiretroviral therapy by transient virologic responders...
  65. ncbi Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active antiretroviral therapy and HIV treatment outcomes in observational studies
    Evan Wood
    BC Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, Canada
    AIDS 17:2629-34. 2003
    ..As such, it is likely that similar selection factors may explain why our findings contrast with several non-randomized studies showing worse clinical outcomes of patients prescribed nevirapine...
  66. ncbi Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy
    David M Moore
    British Columbia Centre for Excellence in HIV AIDS, 608 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6
    J Acquir Immune Defic Syndr 40:288-93. 2005
    ..To examine the independent association of discordant virologic and immunologic responses to highly active antiretroviral therapy (HAART) with mortality...
  67. ncbi Gender differences in HIV-1 RNA rebound attributed to incomplete antiretroviral adherence among HIV-Infected patients in a population-based cohort
    Laura M Kuyper
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada
    J Acquir Immune Defic Syndr 37:1470-6. 2004
    ....
  68. ncbi When to initiate antiretroviral therapy in HIV-1-infected adults: a review for clinicians and patients
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada
    Lancet Infect Dis 5:407-14. 2005
    ....
  69. ncbi A description of a peer-run supervised injection site for injection drug users
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada V6Z 1Y6
    J Urban Health 82:267-75. 2005
    ..The SIS provided a sterile environment for injection drug use without measured negative consequences and demonstrated the feasibility of a peer-driven low-threshold SIS...
  70. ncbi Impact of accessing methadone on the time to initiating HIV treatment among antiretroviral-naive HIV-infected injection drug users
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, BC, Canada
    AIDS 19:837-9. 2005
    ..7% among those who were on MMT at baseline and 44.4% among those not on MMT (log-rank P = 0.001). In a Cox model, the use of MMT was independently associated with an elevated rate of ART use...
  71. ncbi Elevated syringe borrowing among men who have sex with men: a prospective study
    Brandon D L Marshall
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    J Acquir Immune Defic Syndr 46:248-52. 2007
    ..Given that few prospective studies have considered the relationship between sexual activity and syringe sharing, we sought to evaluate syringe sharing among male injection drug users (IDUs) who have sex with men (MSM) in Vancouver...
  72. ncbi The impact of incarceration upon adherence to HIV treatment among HIV-positive injection drug users: a qualitative study
    Will Small
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    AIDS Care 21:708-14. 2009
    ..We sought to qualitatively evaluate experiences with HAART among HIV-positive IDU who had been recently incarcerated within provincial prisons in British Columbia in order to identify factors influencing adherence to treatment...
  73. ncbi The impact of adherence on CD4 cell count responses among HIV-infected patients
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC, Canada
    J Acquir Immune Defic Syndr 35:261-8. 2004
    ..85, 95% CI: 3.15-7.47). CONCLUSIONS: These data demonstrate that substantial CD4 gains are possible among highly advanced adherent patients and should contribute to the ongoing debate over the optimal time to initiate HAART...
  74. ncbi Intensive injection cocaine use as the primary risk factor in the Vancouver HIV-1 epidemic
    Mark W Tyndall
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
    AIDS 17:887-93. 2003
    ..Injection cocaine users remain particularly vulnerable to HIV infection and treatment options for cocaine dependency remain woefully inadequate...
  75. ncbi Risk factors for elevated HIV incidence among Aboriginal injection drug users in Vancouver
    Kevin J P Craib
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, and the Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, USA
    CMAJ 168:19-24. 2003
    ....
  76. ncbi Do supervised injecting facilities attract higher-risk injection drug users?
    Evan Wood
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Prev Med 29:126-30. 2005
    ..We examined whether North America's first SIF was attracting IDUs who were at greatest risk of overdose and blood-borne disease infection...
  77. ncbi Unstable housing, associated risk behaviour, and increased risk for HIV infection among injection drug users
    Trevor A Corneil
    Division of Epidemiology and Population Health, British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
    Health Place 12:79-85. 2006
    ..Implications for policy including more comprehensive housing interventions (e.g. 'floating support') are discussed...
  78. ncbi Unstable housing and hepatitis C incidence among injection drug users in a Canadian setting
    Christina Kim
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    BMC Public Health 9:270. 2009
    ....
  79. ncbi Impact of HAART and injection drug use on life expectancy of two HIV-positive cohorts in British Columbia
    Elisa Lloyd-Smith
    Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
    AIDS 20:445-50. 2006
    ..Members of the injection drug community, particularly those who are not taking HAART, experience elevated mortality in comparison with those without a history of drug use...
  80. ncbi Validity of self-reported adherence among injection drug users
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    J Int Assoc Physicians AIDS Care (Chic) 7:157-9. 2008
    ....
  81. ncbi Factors associated with public injecting among users of Vancouver's supervised injection facility
    Ian McKnight
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Drug Alcohol Abuse 33:319-25. 2007
    ..We evaluated factors associated with public drug injection among a cohort of injection drug users (SEOSI) originally recruited from within Vancouver's supervised injecting facility (SIF)...
  82. ncbi Socioeconomic status, access to triple therapy, and survival from HIV-disease since 1996
    Evan Wood
    Population Health, Division of Epidemiology and Population Health, British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, BC, Canada
    AIDS 16:2065-72. 2002
    ..Our findings highlight the need for the monitoring of therapeutic guidelines to ensure equitable access, as treatment strategies are updated...
  83. ncbi Addiction treatment and stable housing among a cohort of injection drug users
    Anita Palepu
    Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, and Department of Medicine, University of British Columbia, Vancouver, Canada
    PLoS ONE 5:e11697. 2010
    ..Unstable housing and homelessness is prevalent among injection drug users (IDU). We sought to examine whether accessing addiction treatment was associated with attaining stable housing in a prospective cohort of IDU in Vancouver, Canada...
  84. ncbi A longitudinal investigation into excess risk for blood-borne infection among young injection drug users (IUDs)
    Cari L Miller
    University of California at San Diego, School of Medicine, La Jolla, California 92093, USA
    Am J Drug Alcohol Abuse 33:527-36. 2007
    ..These factors underscore the need to target this age group and develop youth friendly interventions to minimize drug-related harms...
  85. ncbi Virologic and immunologic response, clinical progression, and highly active antiretroviral therapy adherence
    Natasha Press
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    J Acquir Immune Defic Syndr 31:S112-7. 2002
    ..Degree of adherence has also been shown to be associated with AIDS-related morbidity, mortality, and hospitalizations...
  86. ncbi A simple, dynamic measure of antiretroviral therapy adherence predicts failure to maintain HIV-1 suppression
    Robert Gross
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, Center for Education and Research in Therapeutics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    J Infect Dis 194:1108-14. 2006
    ....
  87. ncbi The potential public health and community impacts of safer injecting facilities: evidence from a cohort of injection drug users
    Evan Wood
    British Columbia Center for Excellence in HIV/AIDS, St. Paul's Hospital, British Columbia, Canada
    J Acquir Immune Defic Syndr 32:2-8. 2003
    ..Although the impact of SIFs in North America can only be quantified by scientific evaluation, these data indicate a high potential for immediate community and public health benefits if SIFs were presently available...
  88. ncbi Circumstances of first injection among illicit drug users accessing a medically supervised safer injection facility
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, Vancouver
    Am J Public Health 97:1228-30. 2007
    ..These findings indicate that the safer injecting facility's benefits have not been offset by a rise in initiation into injection drug use...
  89. ncbi A review of barriers and facilitators of HIV treatment among injection drug users
    Evan Wood
    AIDS 22:1247-56. 2008
    ..Scale-up of evidence-based HIV treatment and prevention to injection drug users, however, will require increasing political will among both national policy-makers and international public health agencies...
  90. ncbi The future face of coinfection: prevalence and incidence of HIV and hepatitis C virus coinfection among young injection drug users
    Cari L Miller
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
    J Acquir Immune Defic Syndr 36:743-9. 2004
    ..The median number of years injecting for youth seroconverting to a secondary infection was 3 years, suggesting that appropriate public health interventions should be implemented immediately...
  91. ncbi Psychosocial determinants of adherence to highly active antiretroviral therapy among injection drug users in Vancouver
    Thomas Kerr
    Canadian HIV AIDS Legal Network, Montreal, Que, Canada
    Antivir Ther 9:407-14. 2004
    ..As such, there is an urgent need to identify psychosocial determinants of adherence that can be incorporated into interventions designed to promote optimal adherence...
  92. ncbi CD4 cell count response to nonnucleoside reverse transcriptase inhibitor- or protease inhibitor-based highly active antiretroviral therapy in an observational cohort study
    Evan Wood
    J Acquir Immune Defic Syndr 34:347-8. 2003
  93. ncbi Barriers and facilitators to methadone maintenance therapy use among illicit opiate injection drug users in Vancouver
    Cody Callon
    British Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada
    J Opioid Manag 2:35-41. 2006
    ..These findings indicate the need for additional interventions aimed at maximizing coverage of MMT and other treatments for opiate-addicted individuals...
  94. ncbi Why are baseline HIV RNA levels 100,000 copies/mL or greater associated with mortality after the initiation of antiretroviral therapy?
    Evan Wood
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    J Acquir Immune Defic Syndr 38:289-95. 2005
    ..These findings likely explain the association between baseline HIV RNA levels and mortality and have important implications for the development of therapeutic guidelines...
  95. ncbi Risk factors for elevated HIV incidence rates among female injection drug users in Vancouver
    Patricia M Spittal
    British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver
    CMAJ 166:894-9. 2002
    ..Different risk factors for seroconversion for women as opposed to men suggest that sex-specific prevention initiatives are urgently required...
  96. ncbi Validity of self-reported antiretroviral therapy use among injection drug users
    Evan Wood
    J Acquir Immune Defic Syndr 41:530-1. 2006
  97. ncbi The impact of sex partners' HIV status on HIV seroconversion in a prospective cohort of injection drug users
    Thomas Kerr
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    J Acquir Immune Defic Syndr 41:119-23. 2006
    ..We evaluated the HIV status of the sex partners of injection drug users (IDUs) and rates of subsequent HIV seroconversion among a prospective cohort study of IDUs...