Research Topics
| Evan WoodSummaryAffiliation: British Columbia Country: Canada Publications
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Publications
Public crack cocaine smoking and willingness to use a supervised inhalation facility: implications for street disorderKora deBeck
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
Subst Abuse Treat Prev Policy 6:4. 2011....
Social structural factors that shape assisted injecting practices among injection drug users in Vancouver, Canada: a qualitative studyNadia Fairbairn
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, University of British Columbia, 608 1081 Burrard Street, Vancouver, B, C, V6Z 1Y6, Canada
Harm Reduct J 7:20. 2010..We investigated the social structural factors that shape risks related to assisted injection and the harms that may result...
Burden of HIV infection among aboriginal injection drug users in Vancouver, British ColumbiaEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Am J Public Health 98:515-9. 2008..We sought to examine whether there were differential rates of HIV incidence among Aboriginal and non-Aboriginal injection drug users in a Canadian setting...
The role of safer injection facilities in the response to HIV/AIDS among injection drug usersThomas Kerr
BC Centre for Excellence in HIV AIDS, University of British Columbia, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada
Curr HIV/AIDS Rep 4:158-64. 2007....
Circumstances of first crystal methamphetamine use and initiation of injection drug use among high-risk youthEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC V6Z 1Y6, Canada
Drug Alcohol Rev 27:270-6. 2008..Despite the widely noted increase in crystal methamphetamine (CM) use, there are few studies on circumstances of first CM use or correlates of use among high-risk populations (e.g. street-involved youth)...
Police and public health partnerships: evidence from the evaluation of Vancouver's supervised injection facilityKora deBeck
British Columbia Centre for Excellence in HIV AIDS, 608 1081 Burrard Street, Vancouver, B, C, V6Z 1Y6, Canada
Subst Abuse Treat Prev Policy 3:11. 2008..Our study suggests that the SIF provides an opportunity to coordinate policing and public health efforts and thereby resolve some of the existing tensions between public order and health initiatives...
Poor adherence to HIV monitoring and treatment guidelines for HIV-infected injection drug usersE Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
HIV Med 9:503-7. 2008..There is growing concern about access to HIV/AIDS care among injection drug users (IDUs). We examined rates of CD4 cell count monitoring and correlates among HIV-infected IDUs...
Validity of self-reported adherence among injection drug usersThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
J Int Assoc Physicians AIDS Care (Chic) 7:157-9. 2008....
Supervised injecting facilities: time for scale-up?Thomas Kerr
British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital; Vancouver, BC, Canada
Lancet 372:354-5. 2008
Characteristics of injection drug users who participate in drug dealing: implications for drug policyThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
J Psychoactive Drugs 40:147-52. 2008..These findings suggest that elements of "balanced" drug policies may undermine each other and indicate the need for alternative interventions...
Harm reduction in hospitals: is it time?Beth S Rachlis
BC Centre for Excellence in HIV AIDS, St, Paul s Hospital Vancouver, Canada
Harm Reduct J 6:19. 2009..This article describes harm reduction activities within hospitals and areas for future investigation...
Syringe sharing and HIV incidence among injection drug users and increased access to sterile syringesThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, Department of Medicine, University of British Columbia, Vancouver, Canada
Am J Public Health 100:1449-53. 2010..We assessed the effects of syringe exchange program (SEP) policy on rates of HIV risk behavior and HIV incidence among injection drug users...
The Canadian government's treatment of scientific process and evidence: inside the evaluation of North America's first supervised injecting facilityEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
Int J Drug Policy 19:220-5. 2008....
Smoking of crack cocaine as a risk factor for HIV infection among people who use injection drugsKora deBeck
British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Vancouver, BC
CMAJ 181:585-9. 2009..Given the increasing use of crack cocaine, we sought to examine whether use of this illicit drug has become a risk factor for HIV infection...
Incarceration experiences in a cohort of active injection drug usersM J Milloy
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
Drug Alcohol Rev 27:693-9. 2008..Incarceration has been associated with a number of health-related harms among injection drug users (IDU). However, little is known about the prevalence and correlates of incarceration among community-based samples of IDU...
Structural factors associated with an increased risk of HIV and sexually transmitted infection transmission among street-involved youthBrandon D L Marshall
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
BMC Public Health 9:7. 2009....
Potential uptake and correlates of willingness to use a supervised smoking facility for noninjection illicit drug useCourtney L C Collins
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada V6Z 1Y6
J Urban Health 82:276-84. 2005..Although the impact of SSFs in North America can only be quantified by scientific evaluation, these data indicate a potential for public health and community benefits if SSFs were to become available...
Antiretroviral adherence and HIV treatment outcomes among HIV/HCV co-infected injection drug users: the role of methadone maintenance therapyAnita Palepu
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, University of British Columbia, BC, Canada
Drug Alcohol Depend 84:188-94. 2006..We examined the association of methadone maintenance therapy (MMT) with highly active antiretroviral therapy (HAART) adherence and HIV treatment outcomes among a cohort of HIV/HCV co-infected injection drug users (IDUs)...
Changes in injecting practices associated with the use of a medically supervised safer injection facilityJo Anne Stoltz
Clinical Activities, British Columbia Centre of Excellence in HIV AIDS, University of British Columbia, Vancouver, Canada
J Public Health (Oxf) 29:35-9. 2007....
Risk factors for developing a cutaneous injection-related infection among injection drug users: a cohort studyElisa Lloyd-Smith
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
BMC Public Health 8:405. 2008..However, risk factors for CIRI have not been well described in the literature. We sought to characterize the risk factors for current CIRI among individuals who use North America's first supervised injection facility (SIF)...
Effects of police confiscation of illicit drugs and syringes among injection drug users in VancouverDaniel Werb
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
Int J Drug Policy 19:332-8. 2008..Drug market policing has been associated with various harms among injection drug users (IDU). However, little is known about instances in which drugs and injecting equipment are confiscated from IDU in the absence of a formal arrest...
Rationale to evaluate medically supervised safer smoking facilities for non-injection illicit drug usersCourtney L C Collins
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC
Can J Public Health 96:344-7. 2005..Also relevant to this topic are interventions to prevent transition into injection drug use, and SSFs may also be evaluated as a potential strategy to address this concern...
Non-fatal overdose among a cohort of active injection drug users recruited from a supervised injection facilityM J S Milloy
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
Am J Drug Alcohol Abuse 34:499-509. 2008..Our findings indicate that a sub-population of IDU might benefit from overdose prevention interventions. Our findings refute the suggestion that the SIF may increase the likelihood of overdose...
Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapyViviane D Lima
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
AIDS 21:685-92. 2007..To characterize the temporal changes in mortality and life expectancy among HIV-positive individuals initiating antiretroviral therapy in British Columbia, Canada, from 1993 to 2004...
Total lymphocyte count as a possible surrogate of CD4 cell count to prioritize eligibility for antiretroviral therapy among HIV-infected individuals in resource-limited settingsRichard Bedell
Centre for Excellence in HIV/AIDS, University of British Columbia, Vancouver, British Columbia, Canada
Antivir Ther 8:379-84. 2003..Our results suggest that, if appropriately validated, judicious application of total lymphocyte counts could overcome one of the practical obstacles to more widespread provision of antiretroviral therapy in resource-poor settings...
Recent incarceration independently associated with syringe sharing by injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
Public Health Rep 120:150-6. 2005..Few prospective studies are available on the relationship between incarceration and HIV risk among injection drug users (IDUs). The authors evaluated self-reported rates of syringe sharing and incarceration among a cohort of IDUs...
Sociodemographic disparities in access to addiction treatment among a cohort of Vancouver injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
Subst Use Misuse 40:1153-67. 2005..These findings demonstrate low levels of addiction treatment among Vancouver IDUs and suggest that programs may need to be targeted towards specific populations with poor access...
Requiring help injecting independently predicts incident HIV infection among injection drug usersThomas Kerr
British Columbia Centre for Excellence in HIV/AIDS, University of British Columbia, St. Paul's Hospital, Vancouver, Canada
J Acquir Immune Defic Syndr 40:83-8. 2005..79, 95% CI: 1.23-2.62) remained independent predictors of HIV seroconversion. CONCLUSIONS: These data demonstrate the need for interventions to reduce the risk of HIV infection among IDUs who require help injecting...
Factors associated with willingness to participate in a heroin prescription program among injection drug usersCari L Miller
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
J Opioid Manag 1:201-3. 2005..These findings indicate that a clinical trial of prescribed heroin should be able to enroll an appropriate sample of drug users and properly assess the treatment potential of prescribed opiate pharmacotherapy...
Attendance, drug use patterns, and referrals made from North America's first supervised injection facilityMark W Tyndall
Department of Medicine, and BC Centre for Excellence in HIV AIDS, University of British Columbia, St Paul s Hospital, 1081 Burrard Street, Vancouver, BC, Canada
Drug Alcohol Depend 83:193-8. 2006..This analysis was conducted to describe the attendance, demographic characteristics, drug use patterns, and referrals made during the first 18 months of operation...
Incidence and determinants of initiation into cocaine injection and correlates of frequent cocaine injectorsElisa Lloyd-Smith
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital 608 1081, Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
Drug Alcohol Depend 99:176-82. 2009..To investigate the incidence and correlates of cocaine injection initiation and the impacts of daily cocaine injection among a cohort of injection drug users...
Emergence of drug resistance is associated with an increased risk of death among patients first starting HAARTRobert S Hogg
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
PLoS Med 3:e356. 2006..The objective of this study was to determine the impact of the emergence of drug-resistance mutations on survival among persons initiating HAART...
Higher baseline levels of plasma human immunodeficiency virus type 1 RNA are associated with increased mortality after initiation of triple-drug antiretroviral therapyEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
J Infect Dis 188:1421-5. 2003..71; 95% confidence interval, 1.08-2.70; P=.023). If appropriately confirmed, these findings have important implications for the development of therapeutic guidelines...
Crystal methamphetamine use associated with non-fatal overdose among a cohort of injection drug users in VancouverNadia Fairbairn
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC Canada, V6Z 146
Public Health 122:70-8. 2008..To evaluate the prevalence and correlates of non-fatal overdose among a polysubstance-using cohort of injection drug users (IDU) in Vancouver...
HIV risks associated with incarceration among injection drug users: implications for prison-based public health strategiesDaniel Werb
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
J Public Health (Oxf) 30:126-32. 2008..We sought to evaluate the potential impact of incarceration on HIV risk behaviour among the IDU enrolled in a prospective cohort study...
Expanding the reach of harm reduction in Thailand: experiences with a drug user-run drop-in centreThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver BC, V6Z 1Y6 Canada
Int J Drug Policy 21:255-8. 2010..In response, a drug user-led harm reduction centre opened in 2004 in an effort to expand reduction programming in Thailand...
Injection drug use among street-involved youth in a Canadian settingThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, British Columbia, Canada
BMC Public Health 9:171. 2009..We undertook this study to examine the prevalence of injection drug use and associated risks among street-involved youth in Vancouver, Canada...
Requiring help injecting as a risk factor for HIV infection in the Vancouver epidemic: implications for HIV preventionEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver
Can J Public Health 94:355-9. 2003..This risk factor remains poorly understood. The present study investigates this risk factor among Vancouver IDUs...
Nonfatal overdose among a cohort of street-involved youthDaniel Werb
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
J Adolesc Health 42:303-6. 2008..Our findings indicate that nonfatal overdose was common among street-involved youth in our setting, and was associated with various forms of drug use, including methamphetamine use...
The potential public health and community impacts of safer injecting facilities: evidence from a cohort of injection drug usersEvan Wood
British Columbia Center for Excellence in HIV/AIDS, St. Paul's Hospital, British Columbia, Canada
J Acquir Immune Defic Syndr 32:2-8. 2003..Although the impact of SIFs in North America can only be quantified by scientific evaluation, these data indicate a high potential for immediate community and public health benefits if SIFs were presently available...
Prevalence and correlates of untreated human immunodeficiency virus type 1 infection among persons who have died in the era of modern antiretroviral therapyEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
J Infect Dis 188:1164-70. 2003..5%) received antiretroviral medication >or=75% of the time during their first year receiving therapy. The data demonstrate the need for novel interventions to expand HIV care to specific populations...
A description of a peer-run supervised injection site for injection drug usersThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada V6Z 1Y6
J Urban Health 82:267-75. 2005..The SIS provided a sterile environment for injection drug use without measured negative consequences and demonstrated the feasibility of a peer-driven low-threshold SIS...
Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort studyEvan Wood
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
BMJ 338:b1649. 2009..To examine the relation between plasma HIV-1 RNA concentrations in the community and HIV incidence among injecting drug users...
Factors associated with buying and selling syringes among injection drug users in a setting of one of North America's largest syringe exchange programsLaura M Kuyper
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
Subst Use Misuse 41:883-99. 2006..Syringe buyers were more likely to need help injecting, have difficulty finding new syringes, have binged on drugs, and have visited the SEP at least once weekly. Syringe buying most frequently occurred when the SEP was closed...
Incarceration and drug use patterns among a cohort of injection drug usersKora deBeck
British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada
Addiction 104:69-76. 2009..However, the impact of incarceration on deterring drug use remains under-evaluated. We sought to explore the relationship between incarceration and patterns of drug use among people who inject drugs (IDU)...
Predictors of non-fatal overdose among a cohort of polysubstance-using injection drug usersThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada
Drug Alcohol Depend 87:39-45. 2007..Non-fatal overdose is a major determinant of morbidity among injection drug users (IDU). We sought to evaluate factors associated with non-fatal overdose among IDU in Vancouver...
Risks surrounding drug trade involvement among street-involved youthDaniel Werb
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
Am J Drug Alcohol Abuse 34:810-20. 2008..The present study was therefore conducted to investigate factors associated with the street-level drug trade involvement among street-based youth...
Differential impact of adherence on long-term treatment response among naive HIV-infected individualsViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
AIDS 22:2371-80. 2008....
Adherence and plasma HIV RNA responses to highly active antiretroviral therapy among HIV-1 infected injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC
CMAJ 169:656-61. 2003..We evaluated virological responses to HAART among HIV-1 infected patients who were injection drug users (IDUs) in a population-based setting where HIV/AIDS care is delivered free of charge...
Nonadherence increases the risk of hospitalization among HIV-infected antiretroviral naive patients started on HAARTSarah J Fielden
B C Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada, Department of Interdisciplinary Studies, University of British Columbia, Vancouver, British Columbia, Canada
J Int Assoc Physicians AIDS Care (Chic) 7:238-44. 2008..Methods: Analysis was based on a cohort of individuals initiating HAART between 1996 and 2001. The primary outcome was hospitalization for one or more days. Survival methods were used to assess the impact of adherence on hospitalization...
Prevalence and correlates of jugular injections among injection drug usersZia Hoda
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
Drug Alcohol Rev 27:442-6. 2008..We evaluated factors associated with jugular injection among a cohort of injection drug users (IDU) in Vancouver, Canada...
Prevalence and correlates of cervical cancer screening among injection drug usersBruce McKnight
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
J Obstet Gynaecol Can 28:695-9. 2006..This is reassuring, given the elevated risk of cervical cancer among this population. Interventions may be required to improve uptake of screening among older injection drug users and drug users infected with hepatitis C...
Displacement of Canada's largest public illicit drug market in response to a police crackdownEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital and the Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC
CMAJ 170:1551-6. 2004..A large-scale police "crackdown" to control illicit drug use in Vancouver's Downtown Eastside provided us with an opportunity to evaluate the effect...
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based studyJulio S G Montaner
British Columbia Centre for Excellence in HIV AIDS, Providence Health Care, Vancouver, BC, Canada
Lancet 376:532-9. 2010..We aimed to estimate the association between plasma HIV-1 viral load, HAART coverage, and number of new cases of HIV in the population of a Canadian province...
Factors associated with methadone maintenance therapy use among a cohort of polysubstance using injection drug users in VancouverThomas Kerr
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Drug Alcohol Depend 80:329-35. 2005..While the use of MMT was associated with reductions in heroin use and HIV risk behavior, barriers to Aboriginal IDUs were evident, and the association with increased crack cocaine use deserves further study...
Social and structural barriers to housing among street-involved youth who use illicit drugsAndrea Krusi
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada V6Z1Y6
Health Soc Care Community 18:282-8. 2010..Our findings point to the need for housing strategies that include safe, low threshold, harm reduction focused housing options for youth who engage in illicit substance use...
Ongoing drug use and outcomes from highly active antiretroviral therapy among injection drug users in a Canadian settingAndrea Krusi
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
Antivir Ther 15:789-96. 2010..We sought to investigate the influence of drug use patterns on adherence to antiretroviral therapy and virological suppression among IDUs...
Injection drug users' perceptions regarding use of a medically supervised safer injecting facilitySteven Petrar
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver BC, Canada V6Z 1Y6
Addict Behav 32:1088-93. 2007..This study was undertaken to explore injection drug users' experiences and opinions regarding North America's first SIF in Vancouver, Canada...
The impact of adherence on CD4 cell count responses among HIV-infected patientsEvan Wood
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC, Canada
J Acquir Immune Defic Syndr 35:261-8. 2004..85, 95% CI: 3.15-7.47). CONCLUSIONS: These data demonstrate that substantial CD4 gains are possible among highly advanced adherent patients and should contribute to the ongoing debate over the optimal time to initiate HAART...
Frequent needle exchange use and HIV incidence in Vancouver, CanadaEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
Am J Med 120:172-9. 2007..Opposition to needle exchange programs has been fueled by a Vancouver study showing an association between frequent program use and elevated rates of human immunodeficiency virus (HIV) infection among injection drug users...
Slower uptake of HIV antiretroviral therapy among Aboriginal injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
J Infect 52:233-6. 2006..We examined the time to antiretroviral therapy (ART) use among antiretroviral naïve HIV infected injection drug users participating in a prospective cohort study in Vancouver, Canada...
Rate of methadone use among Aboriginal opioid injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC
CMAJ 177:37-40. 2007..We assessed the rate of methadone use in a cohort of opioid injection drug users in Vancouver and investigated whether methadone use was associated with Aboriginal ethnic background...
Directly observed therapy programmes for anti-retroviral treatment amongst injection drug users in Vancouver: access, adherence and outcomesMark W Tyndall
Department of Medicine, University of British Columbia, Canada
Int J Drug Policy 18:281-7. 2007..The programmes initiated in Vancouver demonstrate the positive impact that a comprehensive DOT programme can have on ARV adherence, as well as highlight the challenges that remain...
Impact of baseline viral load and adherence on survival of HIV-infected adults with baseline CD4 cell counts > or = 200 cells/microlEvan Wood
British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 667-1081 Burrard Street, Vancouver, BC, Canada
AIDS 20:1117-23. 2006..89-1.65; P = 0.232). CONCLUSION: HIV RNA > or = 100 000 copies/ml was only associated with mortality among HIV-infected patients initiating HAART with CD4 cell counts > or= 200 cells/microl if the patients were non-adherent...
Harmful microinjecting practices among a cohort of injection drug users in vancouver CanadaBeth Rachlis
BC Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada
Subst Use Misuse 45:1351-66. 2010..We sought to identify factors associated with harmful microinjecting practices in a longitudinal cohort of IDU...
Offer of financial incentives for unprotected sex in the context of sex workCaitlin L Johnston
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
Drug Alcohol Rev 29:144-9. 2010..Commercial sex workers (CSW) are often portrayed as vectors of disease transmission. However, the role clients play in sexual risk taking and related decision making has not been thoroughly characterised...
Drug-related risks among street youth in two neighborhoods in a Canadian settingDan Werb
British Columbia Centre for Excellence in HIV AIDS, 608 1081 Burrard Avenue, Vancouver, BC, Canada V6Z 1Y6
Health Place 16:1061-7. 2010..These results demonstrate the importance of considering neighborhood variation when developing interventions aimed at reducing drug-related harms among street-involved youth at various levels of street entrenchment...
Risk factors for elevated HIV incidence rates among female injection drug users in VancouverPatricia M Spittal
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver
CMAJ 166:894-9. 2002..Different risk factors for seroconversion for women as opposed to men suggest that sex-specific prevention initiatives are urgently required...
An external evaluation of a peer-run "unsanctioned" syringe exchange programEvan Wood
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada BC V6Z 1Y6
J Urban Health 80:455-64. 2003..The findings also suggest that other forms of syringe-exchange programs should consider the benefits of offering fixed site nighttime service...
Gender differences in HIV-1 RNA rebound attributed to incomplete antiretroviral adherence among HIV-Infected patients in a population-based cohortLaura M Kuyper
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada
J Acquir Immune Defic Syndr 37:1470-6. 2004....
Is there a baseline CD4 cell count that precludes a survival response to modern antiretroviral therapy?Evan Wood
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
AIDS 17:711-20. 2003..Our results indicate that the current emphasis of therapeutic guidelines on initiating therapy at CD4 cell counts above 200 x 106 cells/l should be re-examined...
Elevated syringe borrowing among men who have sex with men: a prospective studyBrandon D L Marshall
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
J Acquir Immune Defic Syndr 46:248-52. 2007..Given that few prospective studies have considered the relationship between sexual activity and syringe sharing, we sought to evaluate syringe sharing among male injection drug users (IDUs) who have sex with men (MSM) in Vancouver...
The impact of incarceration upon adherence to HIV treatment among HIV-positive injection drug users: a qualitative studyWill Small
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
AIDS Care 21:708-14. 2009..We sought to qualitatively evaluate experiences with HAART among HIV-positive IDU who had been recently incarcerated within provincial prisons in British Columbia in order to identify factors influencing adherence to treatment...
Public injecting and HIV risk behaviour among street-involved youthBrandon D L Marshall
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada
Drug Alcohol Depend 110:254-8. 2010....
Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active antiretroviral therapy and HIV treatment outcomes in observational studiesEvan Wood
BC Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, Canada
AIDS 17:2629-34. 2003..As such, it is likely that similar selection factors may explain why our findings contrast with several non-randomized studies showing worse clinical outcomes of patients prescribed nevirapine...
"Discordant" increases in CD4 cell count relative to plasma viral load in a closely followed cohort of patients initiating antiretroviral therapyEvan Wood
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
J Acquir Immune Defic Syndr 30:159-66. 2002..Similarities between transient and full virologic responders also appear to be time limited and are often associated with greater cumulative use of antiretroviral therapy by transient virologic responders...
HIV and hepatitis C outbreaks among high-risk youth in Vancouver demands a public health responseCari L Miller
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC
Can J Public Health 96:107-8. 2005..Without focussing such resources, further HIV and HCV infections and subsequent higher health care costs appear imminent...
Nurse-delivered safer injection education among a cohort of injection drug users: evidence from the evaluation of Vancouver's supervised injection facilityR Alan Wood
University of British Columbia School of Nursing, T201 2211 Wesbrook Mall, Vancouver, BC, V6T 2B5 Canada
Int J Drug Policy 19:183-8. 2008..We sought to characterize the state of nursing SIE practice in Vancouver and prospectively examine SIE among SIF users...
Methamphetamine injection independently predicts hepatitis C infection among street-involved youth in a Canadian settingCari L Miller
Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada
J Adolesc Health 44:302-4. 2009..Implementing injection drug use prevention, evidence-based opioid substitution and crystal methamphetamine treatment programs for street-involved youth is critical...
Effect of methadone treatment on incarceration rates among injection drug usersDaniel Werb
British Columbia Centre for Excellence in HIV AIDS, St Pauls Hospital, Vancouver, B C, Canada
Eur Addict Res 14:143-9. 2008..However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect of MMT on rates of incarceration...
The future face of coinfection: prevalence and incidence of HIV and hepatitis C virus coinfection among young injection drug usersCari L Miller
British Columbia Centre for Excellence in HIV AIDS, Vancouver, and Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
J Acquir Immune Defic Syndr 36:743-9. 2004..The median number of years injecting for youth seroconverting to a secondary infection was 3 years, suggesting that appropriate public health interventions should be implemented immediately...
Impact of accessing methadone on the time to initiating HIV treatment among antiretroviral-naive HIV-infected injection drug usersEvan Wood
British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, BC, Canada
AIDS 19:837-9. 2005..7% among those who were on MMT at baseline and 44.4% among those not on MMT (log-rank P = 0.001). In a Cox model, the use of MMT was independently associated with an elevated rate of ART use...
Initiating highly active antiretroviral therapy and continuity of HIV care: the impact of incarceration and prison release on adherence and HIV treatment outcomesAnita Palepu
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, University of British Columbia, BC, Canada
Antivir Ther 9:713-9. 2004..To examine the effect of incarceration within 12 months of initiating highly active antiretroviral therapy (HAART) on non-adherence and HIV-1 RNA suppression...
Impact of HAART and injection drug use on life expectancy of two HIV-positive cohorts in British ColumbiaElisa Lloyd-Smith
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
AIDS 20:445-50. 2006..Members of the injection drug community, particularly those who are not taking HAART, experience elevated mortality in comparison with those without a history of drug use...
Survival sex work and increased HIV risk among sexual minority street-involved youthBrandon D L Marshall
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
J Acquir Immune Defic Syndr 53:661-4. 2010..We sought to determine if street-involved drug-using sexual minority youth are at greater risk for survival sex work and are more likely to engage in risk behaviors with clients...
Intensive injection cocaine use as the primary risk factor in the Vancouver HIV-1 epidemicMark W Tyndall
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada
AIDS 17:887-93. 2003..Injection cocaine users remain particularly vulnerable to HIV infection and treatment options for cocaine dependency remain woefully inadequate...
Risk factors for elevated HIV incidence among Aboriginal injection drug users in VancouverKevin J P Craib
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, and the Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, USA
CMAJ 168:19-24. 2003....
Physical violence among a prospective cohort of injection drug users: a gender-focused approachBrandon D L Marshall
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, and Department of Health Care and Epidemiology, University of British Columbia, Mather Building 5804 Fairview Avenue, Vancouver, BC V6T 1Z3, Canada
Drug Alcohol Depend 97:237-46. 2008..These findings indicate an urgent need for the development of comprehensive programs and structural interventions that take a gender-focused approach to violence among IDU...
Predicting hospitalization among HIV-infected antiretroviral naïve patients starting HAART: determining clinical markers and exploring social pathwaysSarah J Fielden
BC Centre for Excellence in HIV AIDS, Vancouver, BC, US
AIDS Care 20:297-303. 2008..These findings highlight the importance of closely monitoring patients starting therapy with low CD4 cell counts in order to mediate or prevent outcomes requiring hospitalization...
Access to health and social services for IDU: the impact of a medically supervised injection facilityWill Small
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
Drug Alcohol Rev 28:341-6. 2009..This study sought to investigate IDU perspectives regarding the impact of supervised injection facility (SIF) use on access to health-care services...
Coming 'down here': young people's reflections on becoming entrenched in a local drug sceneDanya Fast
Urban Health Research Initiative, British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada V6Z 1Y6
Soc Sci Med 69:1204-10. 2009..Once initiation has occurred, the boundary between safety and risk quickly becomes difficult to navigate, and young people become highly vulnerable to numerous harms...
Drug and HIV-related risk behaviors after geographic migration among a cohort of injection drug usersBeth S Rachlis
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada, V6Z 1Y6
AIDS Behav 14:854-61. 2010..Our findings suggest that, in this setting, risk-taking among IDU declines following periods of migration out of Greater Vancouver...
Increasing use and associated harms of crystal methamphetamine injection in a Canadian settingNadia Fairbairn
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Drug Alcohol Depend 88:313-6. 2007..We evaluated the trends in crystal methamphetamine injection and factors associated with injection of the drug among a cohort of injection drug users (IDU) in Vancouver...
Determinants of cutaneous injection-related infection care at a supervised injecting facilityElisa Lloyd-Smith
British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Vancouver, Canada
Ann Epidemiol 19:404-9. 2009..To evaluate the factors associated with receiving cutaneous injection-related infection (CIRI) care among a representative cohort of supervised injecting facility (SIF) users...
Research Grants
- Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersEvan Wood; Fiscal Year: 2010..By helping to fill a critical information gap, this study has the potential to make a major contribution to public health policies for IDU. ..
- Initiation of injection drug use and HIV risks among street-involved youthEvan Wood; Fiscal Year: 2010....
- Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersEvan Wood; Fiscal Year: 2010..By helping to fill a critical information gap, this study has the potential to make a major contribution to public health policies for IDU. ..
- Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersEvan Wood; Fiscal Year: 2007..By helping to fill a critical information gap, this study has the potential to make a major contribution to public health policies for IDU. ..
- Evaluating the natural history of injection drug useEvan Wood; Fiscal Year: 2007..As such, this project will help inform prevention strategies and interventions throughout North America and elsewhere. ..
- Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersEvan Wood; Fiscal Year: 2010..By helping to fill a critical information gap, this study has the potential to make a major contribution to public health policies forIDU. ..
