Alexandre Prehn Zavascki

Summary

Country: Brazil

Publications

  1. ncbi Risk factors for nosocomial infections due to Pseudomonas aeruginosa producing metallo-beta-lactamase in two tertiary-care teaching hospitals
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Antimicrob Chemother 58:882-5. 2006
  2. ncbi First case report of Neisseria lactamica causing cavitary lung disease in an adult organ transplant recipient
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, 6690 Ipiranga Avenue, 90610 000 Porto Alegre RS, Brazil
    J Clin Microbiol 44:2666-8. 2006
  3. ncbi High prevalence of metallo-beta-lactamase-mediated resistance challenging antimicrobial therapy against Pseudomonas aeruginosa in a Brazilian teaching hospital
    A P Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    Epidemiol Infect 135:343-5. 2007
  4. ncbi The influence of metallo-beta-lactamase production on mortality in nosocomial Pseudomonas aeruginosa infections
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul Porto Alegre, Brazil
    J Antimicrob Chemother 58:387-92. 2006
  5. ncbi Outbreak of carbapenem-resistant Pseudomonas aeruginosa producing SPM-1 metallo-{beta}-lactamase in a teaching hospital in southern Brazil
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Antimicrob Chemother 56:1148-51. 2005
  6. ncbi Severe acute hepatitis due to retroviral rebound syndrome after discontinuation of highly active antiretroviral therapy
    Alexandre Prehn Zavascki
    Infectious Diseases Unit, Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre RS, Brazil
    J Infect 52:e93-4. 2006
  7. ncbi Risk factors for imipenem-resistant Pseudomonas aeruginosa: a comparative analysis of two case-control studies in hospitalized patients
    A P Zavascki
    Infectious Diseases Unit, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Hosp Infect 59:96-101. 2005
  8. ncbi The need for reappraisal of AIDS score weight of Charlson comorbidity index
    Alexandre Prehn Zavascki
    Medical Sciences Post graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    J Clin Epidemiol 60:867-8. 2007
  9. ncbi Reappraisal of Pseudomonas aeruginosa hospital-acquired pneumonia mortality in the era of metallo-beta-lactamase-mediated multidrug resistance: a prospective observational study
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre RS, Brazil
    Crit Care 10:R114. 2006
  10. ncbi Dissemination of Pseudomonas aeruginosa producing SPM-1-like and IMP-1-like metallo-beta-lactamases in hospitals from southern Brazil
    A F Martins
    Pharmaceutical Sciences Post graduate Program, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
    Infection 35:457-60. 2007

Collaborators

Detail Information

Publications23

  1. ncbi Risk factors for nosocomial infections due to Pseudomonas aeruginosa producing metallo-beta-lactamase in two tertiary-care teaching hospitals
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Antimicrob Chemother 58:882-5. 2006
    ..To assess risk factors for nosocomial infections due to Pseudomonas aeruginosa producing metallo-beta-lactamase (MBL-PA) in two teaching hospitals where horizontal dissemination has been demonstrated...
  2. ncbi First case report of Neisseria lactamica causing cavitary lung disease in an adult organ transplant recipient
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, 6690 Ipiranga Avenue, 90610 000 Porto Alegre RS, Brazil
    J Clin Microbiol 44:2666-8. 2006
    ..To our knowledge, this is the first report of pulmonary disease caused by this organism and the second case of N. lactamica infection in an adult patient...
  3. ncbi High prevalence of metallo-beta-lactamase-mediated resistance challenging antimicrobial therapy against Pseudomonas aeruginosa in a Brazilian teaching hospital
    A P Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    Epidemiol Infect 135:343-5. 2007
    ..The extremely high prevalence of MBL production found challenges the choice of therapeutics for P. aeruginosa, and measures to control horizontal dissemination of MBL producers are urgently required...
  4. ncbi The influence of metallo-beta-lactamase production on mortality in nosocomial Pseudomonas aeruginosa infections
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul Porto Alegre, Brazil
    J Antimicrob Chemother 58:387-92. 2006
    ..To assess the effect of metallo-beta-lactamase (MBL) production on Pseudomonas aeruginosa nosocomial infection mortality and to identify the determinants of such effect...
  5. ncbi Outbreak of carbapenem-resistant Pseudomonas aeruginosa producing SPM-1 metallo-{beta}-lactamase in a teaching hospital in southern Brazil
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Antimicrob Chemother 56:1148-51. 2005
    ..To describe the first nosocomial outbreak of Pseudomonas aeruginosa producing SPM-1 metallo-beta-lactamase (MBL) in southern Brazil...
  6. ncbi Severe acute hepatitis due to retroviral rebound syndrome after discontinuation of highly active antiretroviral therapy
    Alexandre Prehn Zavascki
    Infectious Diseases Unit, Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre RS, Brazil
    J Infect 52:e93-4. 2006
    ..Retroviral rebound syndrome is a relatively novel syndrome possible to occur after the discontinuation of antiretroviral therapy. This is the first case reported in the literature of severe acute hepatitis associated with this syndrome...
  7. ncbi Risk factors for imipenem-resistant Pseudomonas aeruginosa: a comparative analysis of two case-control studies in hospitalized patients
    A P Zavascki
    Infectious Diseases Unit, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Hosp Infect 59:96-101. 2005
    ..82) and renal failure (OR 5.00) were associated with IRPA. Our study confirmed that carbapenem exposure is the main risk factor for IRPA, and found that the use of both carbapenem and vancomycin can increase this effect...
  8. ncbi The need for reappraisal of AIDS score weight of Charlson comorbidity index
    Alexandre Prehn Zavascki
    Medical Sciences Post graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    J Clin Epidemiol 60:867-8. 2007
    ..To discuss the need for reappraisal of AIDS score weight of the Charlson comorbidity index...
  9. ncbi Reappraisal of Pseudomonas aeruginosa hospital-acquired pneumonia mortality in the era of metallo-beta-lactamase-mediated multidrug resistance: a prospective observational study
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre RS, Brazil
    Crit Care 10:R114. 2006
    ..The metallo-beta-lactamases (MBLs) are emerging enzymes that hydrolyze virtually all beta-lactams. We aimed to assess P. aeruginosa HAP mortality in a setting of high-rate MBL production..
  10. ncbi Dissemination of Pseudomonas aeruginosa producing SPM-1-like and IMP-1-like metallo-beta-lactamases in hospitals from southern Brazil
    A F Martins
    Pharmaceutical Sciences Post graduate Program, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
    Infection 35:457-60. 2007
    ..We aimed to describe the prevalence and molecular characteristics of SPM-1-like, IMP-1-like and VIM type MBLs among ceftazidime and/or imipenem-resistant nosocomial P. aeruginosa isolates...
  11. ncbi Risk factors for and mortality of extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli nosocomial bloodstream infections
    Silvana Vargas Superti
    Laboratory of Microbiology, Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Rev Inst Med Trop Sao Paulo 51:211-6. 2009
    ..The finding that piperacillin-tazobactam use is a risk factor for ESBL-production in KP or EC BSIs requires attention, since this drug can be recommended to limit the use of third-generation cephalosporins...
  12. ncbi Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA
    Ana Maria Sandri
    Infection Control Department, , 6690 Ipiranga Avenue, Porto Alegre, RS 90610-000, Brazil
    Infect Control Hosp Epidemiol 27:185-7. 2006
    ..aureus infection during the later years of follow-up. Decolonization of nasal carriers of methicillin-resistant S. aureus is probably associated with such findings...
  13. ncbi Indications of carbapenem resistance evolution through heteroresistance as an intermediate stage in Acinetobacter baumannii after carbapenem administration
    Silvana Vargas Superti
    Laboratory of Microbiology, Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Rev Inst Med Trop Sao Paulo 51:111-3. 2009
    ..baumannii warrant further investigations. This is the first description of such phenomenon in vivo and the second report of heteroresistance to carbapenems in A. baumannii...
  14. ncbi Cystic fibrosis patient with Burkholderia pseudomallei infection acquired in Brazil
    Afonso Luis Barth
    Unidade de Microbiologia e Biologia Molecular, Serviço de Patologia Clínica, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
    J Clin Microbiol 45:4077-80. 2007
    ..We report the recovery of B. pseudomallei from the sputum of a cystic fibrosis patient who lives in Brazil. We highlight the importance of careful attention to unusual nonfermentative gram-negative rods in cystic fibrosis patients...
  15. ncbi Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review
    Alexandre Prehn Zavascki
    Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
    J Antimicrob Chemother 60:1206-15. 2007
    ..Since polymyxins will be increasingly used for the treatment of infections caused by MDR bacteria, clinical pharmacokinetic, pharmacodynamic and toxicodynamic studies underpinning the optimal use of these drugs are urgently required...
  16. ncbi Paracoccidioidomycosis in organ transplant recipient: case report
    Alexandre Prehn Zavascki
    , , Porto Alegre, RS, Brazil
    Rev Inst Med Trop Sao Paulo 46:279-81. 2004
    ..Unusual clinical and radiological manifestations of Paracoccidioides brasiliensis infection can occur in immunocompromised patients...
  17. ncbi Mycobacterium tuberculosis resistance in HIV-infected patients from a tertiary care teaching hospital in Porto Alegre, southern Brazil
    M Wolfart
    Microbiology and Molecular Biology Unit, Clinical Pathology Service, Hospital de Clinicas de Porto Alegre, 2350 Ramiro Barcelos St, Porto Alegre, CEP 90 035 903, Rio Grande do Sul, Brazil
    Trans R Soc Trop Med Hyg 102:421-5. 2008
    ..Our findings indicate the need to reappraise regional TB treatment policies and support the recommendation for routine performance of in vitro TB susceptibility tests in all previously treated patients...
  18. ncbi High rate of antimicrobial resistance in Pseudomonas aeruginosa at a tertiary-care teaching hospital in southern Brazil
    Alexandre Prehn Zavascki
    Infect Control Hosp Epidemiol 25:805-7. 2004
  19. ncbi Nosocomial bloodstream infections due to metallo-beta-lactamase-producing Pseudomonas aeruginosa
    Alexandre Prehn Zavascki
    J Antimicrob Chemother 61:1183-5. 2008
  20. ncbi Caution when reconsidering empiric antimicrobial therapy for methicillin-resistant Staphylococcus aureus skin and soft-tissue infections
    Leticia Vale Scribel da Silva
    Am J Surg 196:618-9. 2008
  21. ncbi Determining risk factors for infection with influenza A (H5N1)
    Janice Luisa Lukrafka
    Emerg Infect Dis 13:955-6; author reply 956-. 2007
  22. ncbi Comment on: immune reconstitution inflammatory syndrome: more answers, more questions
    Alexandre Prehn Zavascki
    J Antimicrob Chemother 58:1094; author reply 1094-5. 2006
  23. ncbi Assessing risk factors for acquiring antimicrobial-resistant pathogens: a time for a comparative approach
    Alexandre Prehn Zavascki
    Clin Infect Dis 39:871-2; author reply 872-3. 2004