Research Topics
| M L S MelloSummaryAffiliation: Universidade Estadual de Campinas Country: Brazil Publications
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Detail Information
Publications
Restriction enzyme analysis of DNA methylation in "condensed" chromatin of Ha-ras-transformed NIH 3T3 cellsM L Mello
Department of Cell Biology, Institute of Biology, UNICAMP, Campinas, SP, Brazil
Anal Cell Pathol 20:163-71. 2000..DNA CpG methylation status is thus suggested not to be involved with the higher order chromatin condensation induced by ras transformation in the mentioned NIH 3T3 cell lines...
Nucleus image properties and cell death in MCF-10F cells grown on slide substrates differing in nature and sizeMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13083 863 Campinas, Sao Paulo, Brazil
In Vitro Cell Dev Biol Anim 41:92-6. 2005....
DNA content and chromatin texture of human breast epithelial cells transformed with 17-beta-estradiol and the estrogen antagonist ICI 182,780 as assessed by image analysisMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13083 863 Campinas, SP, Brazil
Mutat Res 617:1-7. 2007..The changes produced by ICI 182,780 alone were attributed to effects other than its well-known anti-estrogenic activity...
17-beta-estradiol affects nuclear image properties in MCF-10F human breast epithelial cells with tumorigenesisMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13083 863 Campinas SP, Brazil
Oncol Rep 18:1475-81. 2007..Studies on epigenetic mechanisms involving DNA methylation and/or the histone code would contribute to a better interpretation of the chromatin supraorganization changes reported herein...
Image analysis of the AgNOR response in ras-transformed human breast epithelial cellsMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, State University of Campinas UNICAMP, 13083 863 Campinas, Brazil
Acta Histochem 110:210-6. 2008..Based on data in the literature, it is also hypothesized that a decreased wild-type p53 level, possibly promoted by the ras transformation, may be associated with the increased AgNOR response...
Cell death evaluation in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17Maria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13084 971 Campinas SP, Brazil
Mutat Res 546:39-43. 2004....
Experimental tendon repair: glycosaminoglycan arrangement in newly synthesized collagen fibersM L S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13084 971 Campinas, SP, Brazil
Cell Mol Biol (Noisy-le-grand) 49:579-85. 2003..The changes in LD during Achilles tendon repair were attributed to gradual modifications in the composition and macromolecular orientation of GAGs relative to the long axis of the collagen fibers...
DNA content, chromatin supraorganization, nuclear glycoproteins and RNA amounts in hepatocytes of mice expressing insulin-dependent diabetesMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, University of Campinas UNICAMP, 13083 863 Campinas, SP, Brazil
Micron 40:577-85. 2009....
Entropy of Feulgen-stained 17-beta-estradiol-transformed human breast epithelial cells as assessed by restriction enzymes and image analysisMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13083 863 Campinas SP, Brazil
Oncol Rep 21:1483-7. 2009..Thus, we assume that a variable epigenetic modulation affecting the higher-order packing states of chromatin in the estrogen-transformed MCF-10F cell model could be evident with the chromatin entropy study by image analysis...
Extended chromatin fibers and chromatin organizationM L S Mello
Department of Anatomy, Cell Biology and Physiology, Institute of Biology, University of Campinas, Brazil
Biotech Histochem 86:213-25. 2011..We focus on light microscopy studies of ECF formation in mouse hepatocytes under different chromatin supraorganization and physiological conditions and in sperm cells with different DNA-protein complexes...
RNA relocation and persistence of nucleolus-like bodies at mitosis in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17M L Mello
Department of Cell Biology, Institute of Biology, UNICAMP, 13084 971 Campinas, SP, Brazil
Anal Cell Pathol 23:137-41. 2001..Some loci which were retained in the BP1-E cells which received a normal chromosome 11 are probably involved with the control of RNA transcript production. Figure 1 on http://www.esacp.org/acp/2001/23-3,4/mello.htm..
Cell death and survival alterations in Malpighian tubules of Triatoma infestans following heat shockM L Mello
Department of Cell Biology, Institute of Biology, State University of Campinas, SP, Brazil
Biochem Cell Biol 79:709-17. 2001..In cells with no induction or accumulation of heat-shock proteins, cell death and the forms of cell survival observed here were the probable consequence...
Optical anisotropy of alcian blue-stained acid glycosaminoglycansMaria Luiza S Mello
Department of Cell Biology, Institute of Biology, State University of Campinas UNICAMP, 13083 863 Campinas, Brazil
Acta Histochem 109:78-85. 2007..The profiles of the anomalous DB curves for the AB-stained sulfoglycoconjugate differed from those of the other materials, probably due to different organization of its dye-binding sites...
Nucleus image properties assessed by video image analysis in mouse hepatocytes under a short lysis for extended chromatin fiber formationBenedicto C Vidal
Department of Cell Biology, Institute of Biology, State University of Campinas (UNICAMP, Campinas, , Brazil
Cytometry A 69:1106-13. 2006....
Apoptotic ratios and mitotic abnormalities in 17-?-estradiol-transformed human breast epithelial MCF-10F cellsL M S Cruz
Departamento de Anatomia, Biologia Celular e Fisiologia e Biofísica, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, SP, Brazil, 13083 863
Braz J Biol 71:487-90. 2011..Present findings are in agreement with the nuclear instability and enrichment of dysregulated genes in the apoptotic process promoted by transformation and tumorigenesis in 17-?-estradiol-treated MCF-10F cells...
Optical anisotropy of collagen fibers of rat calcaneal tendons: An approach to spatially resolved supramolecular organizationBenedicto de Campos Vidal
Department of Cell Biology, Institute of Biology, University of Campinas, SP, Brazil
Acta Histochem 112:53-61. 2010....
Collagen type I amide I band infrared spectroscopyBenedicto de Campos Vidal
Department of Anatomy, Cell Biology, and Physiology and Biophysics, Institute of Biology, University of Campinas UNICAMP, 13083 863 Campinas SP, Brazil
Micron 42:283-9. 2011..This conclusion is additionally supported by differences in collagen solubility and biochemical/biomechanical properties of the tendons...
Structural organization of collagen fibers in chordae tendineae as assessed by optical anisotropic properties and Fast Fourier transformBenedicto de Campos Vidal
Department of Cell Biology, Institute of Biology, UNICAMP, Campinas SP, Brazil
J Struct Biol 167:166-75. 2009..A statistically helical structure is assumed for the supraorganization of the collagen fibers in the chordae tendineae, which is suggested here to be a chiral body...
DNA content, chromatin texture and nuclear morphology in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17Maria Luiza S Mello
Department of Cell Biology, Institute of Biology, UNICAMP, Campinas, Sao Paolo, Brazil
Cytometry A 52:70-6. 2003....
Prevalence and intensity of infection, metacyclogenesis and nuclear phenotypes in Panstrongylus megistus (Burmeister, 1835) after ingestion of Trypanosoma cruzi (Chagas, 1909) II and subjection to heat shockS L Garcia
Departamento de Anatomia, Biologia Celular e Fisiologia e Biofísica, Universidade Estadual de Campinas, Campinas, SP, Brazil, 13083 863
Braz J Biol 71:491-500. 2011..cruzi, and the observed resistance to heat shock developed by P. megistus nymphs are suggestive that they should be considered when adequate conditions for rearing these infected insects in the laboratory are pursued...
Feulgen-DNA response and chromatin condensation in Malpighian tubules of Melipona rufiventris and Melipona quadrifasciata (Hymenoptera, Apoidea)André Roberto Mampumbu
Department of Cell Biology, Institute of Biology, University of Campinas UNICAMP, C P 6109, 13083 863 Campinas, SP, Brazil
Cell Biol Int 32:935-9. 2008..The depurination kinetics studied here with the Feulgen reaction were revealed to be more pertinent than the C-banding technique in establishing differences in levels of chromatin condensation for these cell nuclei...
Supramolecular order following binding of the dichroic birefringent sulfonic dye Ponceau SS to collagen fibersB C Vidal
Department of Cell Biology, Institute of Biology, State University of Campinas UNICAMP, P O Box 6109, 13083 863 Campinas, SP, Brazil
Biopolymers 78:121-8. 2005..The presence of LD in the Ponceau SS-collagen complex even in unpolarized light indicated that this complex can act as a polarizer...
Eye pigments of the blood-sucking insect, Triatoma infestans Klug (Hemiptera, Reduviidae)A S Moraes
Departamento de Biologia Celular, Instituto de Biologia, UNICAMP, Campinas, SP, 13083-863, Brazil
Braz J Biol 65:477-81. 2005..These data support other findings regarding the similarities between black- and red-eyed specimens of T. infestans for other characteristics...
Chromatin supraorganization, DNA fragmentation, and cell death in snake erythrocytesMaristela Miyamoto
Department of Cell Biology, Institute of Biology, UNICAMP, 13084-971, Campinas, SP, Brazil
Biochem Cell Biol 83:15-27. 2005..The differences in erythrocyte cell biology reported here may be related to hemoglobin variants selected in the mentioned snake species and that would lead the cells to different resistances to unfavorable environmental conditions...
Chromatin supraorganization and extensibility in mouse hepatocytes following starvation and refeedingAlberto S Moraes
Department of Cell Biology, Institute of Biology, State University of Campinas (UNICAMP, 13083-863 Campinas, , Brazil
Cytometry A 63:94-107. 2005..These changes are suggested as favoring the silencing and reactivation of transcriptional activities, depending on the organism's nutritional state...
Effect of sequential heat and cold shocks on nuclear phenotypes of the blood-sucking insect, Panstrongylus megistus (Burmeister) (Hemiptera, Reduviidae)Simone L Garcia
Departamento de Parasitologia, Instituto de Biologia, UNICAMP, 13084-971Campinas, SP, Brasil
Mem Inst Oswaldo Cruz 97:1111-6. 2002..It is concluded that different sequential thermal shocks can trigger different mechanisms of cellular protection against stress in P. megistus, favoring the insect to adapt to various ecotopes...
Age-related association of rDNA and telomeres with the nuclear matrix in mouse hepatocytesAlberto S Moraes
Department of Cell Biology, Institute of Biology, State University of Campinas, 13083 863 Campinas, Sao Paulo, Brazil
Cell Biol Int 34:925-31. 2010..We assume that active rRNA genes associate with the nuclear matrix, while DNA loops contain silent sequences. Transcription of each 45S rDNA repeat unit is suggested to be dependent on its interaction with the nuclear matrix...
Standardization of bulb and root sample sizes for the Allium cepa testA Barberio
Department of Anatomy, Cell Biology, Physiology and Biophysics, Institute of Biology, University of Campinas, Campinas, SP, 13083 863, Brazil
Ecotoxicology 20:927-35. 2011..cepa test...
Chromatin supraorganization, DNA fragmentation, and cell death in erythrocytes of the rattlesnake, Crotalus durissus terrificus (Serpentes, Viperidae), infected with the protozoan, Hepatozoon spp. (Apicomplexa, Hepatozoidae)Maristela Miyamoto
Department of Cell Biology, Institute of Biology, State University of Campinas UNICAMP, C P 6109, 13083 863 Campinas, SP, Brazil
Cell Biol Int 31:494-9. 2007..The Hepatozoon infection is thus suggested to accelerate destruction of erythrocytes in the rattlesnake, not only affecting cells harbouring the parasite, but also in those without it...
Chromatin supraorganization and extensibility in mouse hepatocytes with development and agingAlberto S Moraes
Department of Cell Biology, Institute of Biology, State University of Campinas UNICAMP, Campinas, Sao Paulo, Brazil
Cytometry A 71:28-37. 2007..It is expected that they could also change with mouse development and aging...
The Con-A-peroxidase method for tissue localization of glucosyl and mannosyl groups applied to mouse hepatocytes and chicken erythrocytesAlberto S Moraes
Department of Cell Biology, Institute of Biology, State University of Campinas (UNICAMP, P.O. Box 6019, 13083-863, Campinas, , Brazil
Acta Histochem 108:475-9. 2006..These conditions may alter the Con-A conformation, enabling the lectin molecule to enter the cell nucleus and bind to nuclear glycoproteins, thus allowing their localization and quantification...
Changes in nuclear phenotype frequencies following sequential cold shocks in Triatoma infestans (Hemiptera, Reduviidae)Silvana G P Campos
Departamento de Biologia Celular, Instituto de Biologia, Universidade Estadual de Campinas, SP, Brasil
Mem Inst Oswaldo Cruz 97:857-64. 2002..infestans. The decreased frequency of apoptosis and necrosis following sequential cold shocks including under fasting conditions, indicated that tolerance to sequential cold shocks occurred in T. infestans of the mentioned origin...
