Research Topics
| Vera Luiza CapelozziSummaryCountry: Brazil Publications
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Detail Information
Publications
Collagen V-induced nasal tolerance downregulates pulmonary collagen mRNA gene and TGF-beta expression in experimental systemic sclerosisAna Paula P Velosa
Rheumatology Division of the School of Medicine of the University of São Paulo, Sao Paulo, Brazil
Respir Res 11:1. 2010..The purpose of this study was to evaluate collagen deposition, mRNA collagen synthesis and TGF-beta expression in the lung tissue in an experimental model of scleroderma after collagen V-induced nasal tolerance...
Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injuryPedro L Silva
Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Av Carlos Chagas Filho, Rio de Janeiro 21949 902, Brazil
Crit Care 14:R114. 2010....
Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsisGisele P Oliveira
Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro 21949 902, Brazil
Crit Care 13:R74. 2009....
Role of immunohistochemistry in the diagnosis of lung cancerVera Luiza Capelozzi
Departamento de Patologia, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
J Bras Pneumol 35:375-82. 2009..Immunohistochemistry can be used in the routine diagnosis of lung cancer, in order to identify biological markers (diagnostic and prognostic). The essential immunohistochemistry panels will be discussed in this review...
What have anatomic and pathologic studies taught us about acute lung injury and acute respiratory distress syndrome?Vera Luiza Capelozzi
Departament of Pathology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
Curr Opin Crit Care 14:56-63. 2008..This review addresses anatomic/pathologic differences between acute lung injury and acute respiratory distress syndrome lungs...
Refractory remodeling of the microenvironment by abnormal type V collagen, apoptosis, and immune response in non-small cell lung cancerPaola Souza
Departament of Pathology, Faculdade de Medicina da Universidade de São Paulo 01246 903, Brazil
Hum Pathol 41:239-48. 2010....
Pulmonary histopathological alterations in patients with acute respiratory failure: an autopsy studyAlexandre de Matos Soeiro
Faculdade de Medicina da Universidade de Sao Paulo FMUSP, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
J Bras Pneumol 34:67-73. 2008....
Collagen V and vascular injury promote lung architectural changes in systemic sclerosisEdwin Roger Parra
Departament of Pathology, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Clin Respir J 3:135-42. 2009....
Histomorphometric analysis of cutaneous remodeling in the early stage of the scleroderma modelCristiane Carla de Oliveira
Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil
Clinics (Sao Paulo) 64:577-83. 2009..In the present study, our aim was to assess the skin alterations in animals with scleroderma during the first stages of disease induction...
Biopsy-proven pulmonary determinants of heart diseaseFelipe Muniz de Castro Zampieri
Department of Pathology, Faculdade de Medicina, Universidade de Sao Paulo, Av Dr Arnaldo 455, Sao Paulo, SP, CEP 01246 903, Brazil
Lung 188:63-70. 2010....
Abnormal collagen deposition in synovia after collagen type V immunization in rabbitsLuciana Tsuzuki Ichicawa Ogido
Discipline of Rheumatology, Faculty of Medicine, University of Sao Paulo, Brazil
Histol Histopathol 23:263-9. 2008..Certainly, this experimental model induced by collagen V immunization will bring new insights in to pathogenic mechanisms and allow the testing of new therapeutic strategies to ameliorate the prognosis for scleroderma patients...
Association between decreases in type V collagen and apoptosis in mouse lung chemical carcinogenesis: a preliminary model to study cancer cell behaviorEdwin Roger Parra
Departament of Pathology, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
Clinics (Sao Paulo) 65:425-32. 2010..The importance of type V collagen and its relationships with other types of collagen and with vascular and epithelial apoptosis were studied in a model of chemical carcinogenesis in the mouse lung...
Morphometric evaluation of NB84, synaptophysin and AgNOR is useful for the histological diagnosis and prognosis in peripheral neuroblastic tumors (pNTs)Aparecida de Cássia Carvalho
Department of Pathology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
Clinics (Sao Paulo) 62:731-40. 2007....
Post-mortem histological pulmonary analysis in patients with HIV/AIDSAlexandre de Matos Soeiro
Pathology, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 63:497-502. 2008..This study considers 250 autopsies of HIV/AIDS patients who died of acute respiratory failure and describes the demographic data, etiology, and histological pulmonary findings of the various pathologies...
Autopsy-proven causes of death in lungs of patients immunocompromised by secondary interstitial pneumoniaAlberto Antonio Terrabuio Junior
Department of Pathology, Sao Paulo University Medical School, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 62:69-76. 2007....
Semiquantitative assessment of surgical lung biopsy: predictive value and impact on survival of patients with diffuse pulmonary infiltrateMauro Canzian
Division of Respiratory Diseases, Heart Institute, Medical School, Sao Paulo University, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 62:23-30. 2007..The present study was designed to investigate the prognostic contribution provided by detailed tissue analysis in diffuse infiltrates...
Idiopathic and collagen vascular disease nonspecific interstitial pneumonia: clinical significance of remodeling processCarlos Henrique Chirnev Felício
Department of Pathology, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil
Lung 185:39-46. 2007..Patients with greater than 1.5% of elastic fibers comprise a subset with a high risk for dying due to NSIP and may be an appropriate target for prospective studies...
Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosisDaniel Reis Waisberg
Departament of Pathology, Faculdade de Medicina da Universidade de Sao Paulo, Brasil
Hum Pathol 41:385-91. 2010..We conclude that abnormal type 2 alveolar epithelial cells telomerase/apoptosis balance may reduce alveolar epithelial regenerative capacity, thus contributing to the early remodeling response in usual interstitial pneumonia...
Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failureVera Luiza Capelozzi
Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 65:1229-37. 2010..Cases of H1N1 and other pulmonary infections evolve to acute respiratory failure and death when co-infections or lung injury predominate over the immune response, thus requiring early diagnosis to improve treatment...
Individual risk prediction of nodal and distant metastasis for patients with typical bronchial carcinoid tumorsJoão Carlos Das-Neves-Pereira
Thoracic Surgery Department of Sao Paulo University Medical School, Sao Paulo, SP, Brazil
Eur J Cardiothorac Surg 34:473-7; discussion 477-8. 2008..Our objective was to screen for predictive criteria of bronchial typical carcinoid tumor aggressiveness based on a logistic regression model using clinical, pathological and biomolecular data...
Effects of inducible nitric oxide synthase inhibition in bronchial vascular remodeling-induced by chronic allergic pulmonary inflammationCarla Máximo Prado
Department of Medicine, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
Exp Lung Res 37:259-68. 2011..It reveals new therapeutic strategies and some possible mechanism related to specific iNOS inhibition to control vascular remodeling...
Changes in histoanatomical distribution of types I, III and V collagen promote adaptative remodeling in posterior tibial tendon ruptureErika Satomi
Department of Rheumatology, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 63:9-14. 2008..Posterior tibial tendon dysfunction is a common cause of adult flat foot deformity, and its etiology is unknown...
Using electron microscopy and multivariate cluster analysis to determine diagnosis and prognosis in cases of neuroendocrine lung carcinomaCecília Aparecida Vaiano Farhat
Pontifical Catholic University, Sao Paulo, Brazil
J Bras Pneumol 34:804-11. 2008..To establish reproducible electron microscopic criteria for identifying the four major types of neuroendocrine tumors of the lung: carcinoid; atypical carcinoid; large cell neuroendocrine carcinoma; and small cell carcinoma...
Abnormal deposition of collagen/elastic vascular fibres and prognostic significance in idiopathic interstitial pneumoniasEdwin Roger Parra
Department of Pathology, Sao Paulo Medical School, University of Sao Paulo, Dr Arnaldo Avenue 455, Sao Paulo 01246 903, Brazil
Thorax 62:428-37. 2007..Vascular remodelling has recently been shown to be a promising pathogenetic indicator in idiopathic interstitial pneumonias (IIPs)...
Systemic sclerosis and idiopathic interstitial pneumonia: histomorphometric differences in lung biopsiesEdwin Roger Parra
University of Sao Paulo School of Medicine, CEP 01246 903, Sao Paulo, Brazil
J Bras Pneumol 35:529-40. 2009....
Predictive models for diagnosis of pleural effusions secondary to tuberculosis or cancerRoberta K B Sales
Pulmonary and Clinical Laboratory ICHC Divisions, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
Respirology 14:1128-33. 2009..This study aimed to identify diagnostic models based on clinical and laboratory variables to differentiate tuberculous from malignant pleural effusions...
Thrombosis in small and medium-sized pulmonary arteries in Wegener's granulomatosis: a confocal laser scanning microscopy studyAlfredo Nicodemos Cruz Santana
Faculdade de Medicina da Universidade de Sao Paulo, University of Sao Paulo School of Medicine, Hospital das Clinicas, Sao Paulo, Brazil
J Bras Pneumol 36:724-30. 2010..The objective of this study was to quantify fibrin thrombi in the SMSPA of patients with WG...
Adenocarcinoma of the esophagogastric junction: relationship between clinicopathological data and p53, cyclin D1 and Bcl-2 immunoexpressionsDárcio Matenhauer Lehrbach
Department of Gastroenterology, University of Sao Paulo School of Medicine, Sao Paulo, SP, Brazil
Arq Gastroenterol 46:315-20. 2009..Esophagogastric junction adenocarcinoma has an aggressive behavior, and TNM (UICC) staging is not always accurate enough to categorize patient's outcome...
[Immunophenotyping and gene rearrangement analysis in lymphoid/lymphoproliferative disorders of the lungs]Camila Cristina Ishikawa
Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
J Bras Pneumol 33:625-34. 2007..To determine the usefulness, in routine practice, of using polymerase chain reaction to analyze B and T lymphocyte clonality in pulmonary tissue as a tool for the diagnosis of pulmonary lymphoproliferative disorders...
Parenchymal and vascular interactions in the pathogenesis of nonspecific interstitial pneumonia in systemic sclerosis and idiopathic interstitial pneumoniaErika Franco de Carvalho
Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil
Respiration 76:146-53. 2008....
Temporal evolution of epithelial, vascular and interstitial lung injury in an experimental model of idiopathic pulmonary fibrosis induced by butyl-hydroxytolueneEdwin Roger Parra
Departamento de Patologia, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Int J Exp Pathol 89:350-7. 2008..This feature is important in the identification of animal models of idiopathic pulmonary fibrosis that can accurately reflect the pathogenesis and progression of the human disease...
Preservation of alpha-3 neuronal nicotinic acetylcholine receptor expression in sympathetic Ganglia after brain deathNabor Bezerra de Moura Júnior
Division of Thoracic Surgery, Heart Institute, University of Sao Paulo, Av Dr Eneas de Carvalho Aguiar, 44, 2 andar, 05403 900, Sao Paulo, Sao Paulo, Brazil
Mol Neurobiol 45:362-5. 2012..47% of brain-dead subjects and in 7.23% of control subjects (p?=?0.31). Brain death did not affect the results of the immunohistochemical analysis of sympathetic ganglia, and its use as study group is feasible...
Protective effects of ascorbic acid pretreatment in a rat model of intestinal ischemia-reperfusion injury: a histomorphometric studyOscar Haruo Higa
Department of Pathology, Sao Paulo University Medical School, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 62:315-20. 2007..Ascorbic acid has shown promise in attenuation of intestinal ischemia-reperfusion (I/R) injury. The aim of this study was to determine the protective effects of ascorbic acid on intestinal morphology during IR injury in rats...
Collagen V nasal tolerance in experimental model of systemic sclerosisAna Paula Pereira Velosa
Discipline of Reumatology, Faculty of Medicine, University of Sao Paulo, Av Dr Arnaldo 455 cep 01246 903, Sao Paulo, SP, Brazil
Arch Dermatol Res 299:177-89. 2007..Collagen V nasal tolerance promotes regression of skin remodeling process in an experimental model of SSc. We suggest that nasal tolerance with type V collagen can be a promising therapeutic option to treat scleroderma patients...
Evaluation of the use of transbronchial biopsy in patients with clinical suspicion of interstitial lung diseaseCristiano Claudino Oliveira
Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil
J Bras Pneumol 37:168-75. 2011....
Hyaluronidase splice variants are associated with histology and outcome in adenocarcinoma and squamous cell carcinoma of the lungVanessa Karen de Sá
Department of Pathology, Faculdade de Medicina, Universidade de Sao Paulo, 01246903 São Paulo, Brasil
Hum Pathol 43:675-83. 2012..HYAL splice variants are associated with histology and outcome, suggesting that strategies aimed at modulating their levels may be effective for lung cancer treatment...
Inflammatory cell phenotyping of the pulmonary interstitium in idiopathic interstitial pneumoniaEdwin Roger Parra
Department of Pathology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
Respiration 74:159-69. 2007..Investigations of inflammatory cells in IIP have show that eosinophils, neutrophils and T cells may be associated with a poorer prognosis...
Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinomaFlávio Henrique Ferreira Galvão
Department of Gastroenterology, University of Sao Paulo Medical School, Sao Paulo, Brazil
Cancer Chemother Pharmacol 65:607-10. 2010..Gemcitabine-induced pulmonary toxicity is usually a dramatic condition. Physicians should suspect pulmonary toxicity in patients with respiratory distress after gemcitabine chemotherapy, mainly in elderly patients...
Correlation between surgical lung biopsy and autopsy findings and clinical data in patients with diffuse pulmonary infiltrates and acute respiratory failureMauro Canzian
Division of Respiratory Diseases, Heart Institute, , , SP, Brazil
Clinics 61:425-32. 2006..Surgical lung biopsy may reveal a specific diagnosis that requires distinct treatment, and it would probably have an impact in lowering the mortality of these patients...
Morphological aspects as prognostic factors in malignant mesothelioma: a study of 58 casesAlexandre Bottrel Motta
Department of Pathology School of Medicine, , SP, Brazil
J Bras Pneumol 32:322-32. 2006..Therefore, histopathological analysis offers a powerful weapon with great potential to inform decisions regarding the use of adjuvant chemotherapy after surgical excision of a mesothelioma...
[Histopathological diagnosis of pneumoconiosis]Vera Luiza Capelozzi
, Faculdade de Medicina, , , SP, Brasil
J Bras Pneumol 32:S99-112. 2006....
Nuclear markers (star volume, mitotic index, AgNOR and Ki-67) of the primary tumor and its metastasis in non-small cell lung carcinomasRoberto Storte Matheus
Department of Thoracic Surgery, University of Mogi das Cruzes, , Brazil
Pathol Res Pract 200:13-23. 2004..g., cyclin D1, p27, and cyclin E. These would influence clinical decisions or different therapeutic approaches in advanced stage disease of non-small cell lung cancer...
[Pre-operative sera levels of CEA and CA19-9 and tissular distribution of tumor marker CA19-9 in colorectal carcinoma: correlation with morphological features of neoplasia]José Roberto Martins de Souza
Serviço de Gastroenterologia Cirúrgica, Hospital do Servidor Publico Estadual, Sao Paulo, SP
Rev Col Bras Cir 37:106-13. 2010..To compare sera levels of CEA and CA19-9 and tissular expression of the CA19-9 and to correlate these with morphological features of the colorectal carcinoma...
Impact of open lung biopsy on refractory acute respiratory failureCarmen Silvia Valente Barbas
Intensive Care Unit, Hospital Israelita Albert Einstein, , Brazil
J Bras Pneumol 32:418-23. 2006....
Interstitial and vascular type V collagen morphologic disorganization in usual interstitial pneumoniaEdwin Roger Parra
Department of Pathology, , , Brazil
J Histochem Cytochem 54:1315-25. 2006..We concluded that in the different temporal stages of UIP, vascular/parenchyma collagen type V is increased, in disarray, and is the most important predictor of survival...
Immunohistochemistry quantification by a digital computer-assisted method compared to semiquantitative analysisLeandro Luongo de Matos
Biochemistry Department, Molecular Biology Laboratory, Faculty of Medicine, ABC Foundation, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 61:417-24. 2006..To compare immunostaining quantification obtained by a digital computer-assisted method with the well-established semiquantitative analysis...
Ultrastructural acute features of active remodeling after chemical pleurodesis induced by silver nitrate or talcEduardo H Genofre
Laboratory of Pleura, Pulmonary Division, Heart Institute (InCor, , , Brazil
Lung 183:197-207. 2005....
Autopsy-proven determinants of death in HIV-infected patients treated for pulmonary tuberculosis in Sao Paulo, BrazilEliana Battaggia Gutierrez
Division of Infectious Diseases, Hospital das Clinicas, School of Medicine, , Brazil
Pathol Res Pract 198:339-46. 2002..Early treatment for tuberculosis and associated diseases can improve survival and the quality of life even of highly immunosuppressed patients...
Pulmonary and mediastinal "sarcoidosis" following surgical resection of cancerEdwin Roger Parra
Department of Pathology, , Medical School, Av, Arnaldo 455, , Brazil
Pathol Res Pract 200:701-5. 2004....
Structural features of epithelial remodeling in usual interstitial pneumonia histologic patternAline Lourenso Baptista
Department of Pathology, , , Brazil
Lung 184:239-44. 2006....
Heterogeneous remodeling of lung vessels in idiopathic pulmonary fibrosisEdwin Roger Parra
Department of Pathology, , Av. Dr. Arnaldo 455, , Brazil
Lung 183:291-300. 2005..This vascular regression may be responsible for the impaired wound healing and progressive fibroproliferation found in patients with IPF. Further studies are needed to determine whether this relationship is causal or consequential...
Pulmonary morphofunctional effects of mechanical ventilation with high inspiratory air flowCristiane Sousa Nascimento Baez Garcia
Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Crit Care Med 36:232-9. 2008..We investigated whether mechanical ventilation with high air flow could yield lung mechanical stress even in normal animals...
Chronic eosinophilic pneumonia secondary to long-term use of nitrofurantoin: high-resolution computed tomography findingsRosane Rodrigues Martins
Armed Forces Hospital Brasília, Brazil
J Bras Pneumol 34:181-4. 2008..The patient had previously been submitted to an open lung biopsy. The diagnosis of chronic eosinophilic pneumonia was confirmed through a review of the biopsy...
Nonhomogeneous density of CD34 and VCAM-1 alveolar capillaries in major types of idiopathic interstitial pneumoniaEdwin Roger Parra
Division of Pathology, Heart Institute (InCor, , Brazil
Lung 183:363-73. 2005..These results indicate the presence of temporal nonhomogeneic vascular remodeling indiopathic interstitial pneumonia...
