Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label studyZahit Bolaman
Department of Internal Medicine, Division of Hematology, Adnan Menderes University Medical School, Aydin, Turkey
Clin Ther 25:3124-34. 2003
..It has been suggested by some investigators that oral (p.o.) cobalamin treatment may be as effective in the treatment of this condition, with the advantages of ease of administration and lower cost...
Effects of atorvastatin on coagulation parameters and homocysteine in patients with primary hypercholesterolemiaZahit Bolaman
Division of Hematology, Department of Internal Medicine, Adnan Menderes University Medical School, 09100 Aydin, Turkey
J Natl Med Assoc 98:1273-7. 2006
..The mechanism of the antithrombotic action of statins is unclear. We evaluated the effects of atorvastatin on the coagulation parameters and homocysteine levels of patients with primary hypercholesterolemia...
Type I Gaucher's disease with homozygous R463C mutation without neurological involvementZahit Bolaman
Adnan Menderes University Medical School, Division of Haematology Oncology, Bilim Dali, 09100 Aydin, Turkey
Haematologia (Budap) 32:487-93. 2002
..R463C (i.e., 1504C-->T) mutation may predict neurological involvement in Gaucher's disease. We report a 36-year-old Turkish man with type I Gaucher's disease with homozygous R463C mutation without neurological involvement...
Granulocytic sarcoma of the ovotestis: an association of myelodysplastic syndrome and hermaphroditismZahit Bolaman
Department of Hematology, Faculty of Medicine, Adnan Menderes University, Aydin 09100, Turkey
Leuk Lymphoma 45:1285-7. 2004
..Here we report a rare patient with myelodysplastic syndrome, EMD and hermaphroditism. To our knowledge this is the first case of MDS, EMD and hermaphroditism...
Migratory nodules in the lung: lymphomatoid granulomatosisZahit Bolaman
Division of Haematology, Department of Internal Medicine, Adnan Menderes University Medical School, Aydin, Turkey
Leuk Lymphoma 44:197-200. 2003
..LG is a rare disease and a difficult diagnosis in the routine clinical practice. This report emphasises that, LG should be considered especially when there are migratory nodules of varying sizes in lungs...
Treatment of blastic phase chronic myeloid leukemia with mitoxantrone, cytosine arabinoside and high dose methylprednisoloneZahit Bolaman
Adnan Menderes University Medical School, Department of Internal Medicine, Aydin, Turkey
Haematologia (Budap) 32:49-57. 2002
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The protective effects of amifostine on adriamycin-induced acute cardiotoxicity in ratsZahit Bolaman
Department of Internal Medicine, Division of Hematology, Adnan Menderes University Medical School, Aydin, Turkey
Tohoku J Exp Med 207:249-53. 2005
..Therefore, amifostine may ameliorate the adriamycin-induced acute cardiotoxicity...
Thrombotic thrombocytopenic purpura as the first manifestation of metastatic adenocarcinoma in a young womanGurhan Kadikoylu
Adnan Menderes University Medical Faculty, Division of Hematology, 09100 Aydin, Turkey
Transfus Apher Sci 42:39-42. 2010
..In conclusion, malignancy and bone marrow involvement should be considered when associated with leukoerythroblastic picture and TTP...
Emergent therapy with therapeutic plasma exchange in acute recurrent pancreatitis due to severe hypertriglyceridemiaGurhan Kadikoylu
Medical Faculty, Division of Hematology, Adnan Menderes University, Aydin, Turkey
Transfus Apher Sci 43:285-9. 2010
..Although there is no definitive evidence for early application of TPE in severe hypertriglyceridemia-induced acute pancreatitis yet, therapy with TPE may be of benefit, improving the clinical course...
The development of gastric cancer in a patient with polycythemia Vera, 3P deletion, and JAK2 V617F mutationOzlem Ayvaz
Division of Hematology, Adnan Menderes University Medical Faculty, 09100 Aydin, Turkey
J Gastrointest Cancer 41:254-6. 2010
..In conclusion, cytogenetic examination may be important in both the development and the diagnosis of hematological malignancies and solitary tumors. So the patients should be followed closely...
Therapeutic apheresis: results from a single center in TurkeyIrfan Yavasoglu
Adnan Menderes University Medical Faculty, Divisions of Hematology, 09100 Aydin, Turkey
Transfus Apher Sci 36:249-53. 2007
..Therapeutic apheresis (TA) is carried out for a broad spectrum of diseases and syndromes...
Chronic myeloid leukemia following the treatment of rectal adenocarcinomaGurhan Kadikoylu
Division of Hematology, Adnan Menderes University Medical Faculty, 09100, Aydin, Turkey
Med Oncol 25:467-70. 2008
..The possibility of a relationship between CML and the chemotherapeutic agents in colorectal carcinoma should be further evaluated...
A new perspective on cardiotoxicity of 5-fluorouracil. A novel research tool 'cardiac ultrasonic integrated backscatter analysis' indicates transient, subclinical myocardial dysfunction due to high-dose leucovorin and infusional 5-fluorouracil regimenSabri Barutca
Department of Medical Oncology, Adnan Menderes University Hospital, Aydin, Turkey
Chemotherapy 50:113-8. 2004
..The pathophysiology of 5-fluorouracil (5-FU) cardiotoxicity is still controversial. The objective of this study was to assess the influence of high-dose leucovorin and infusional 5-FU regimen (HDLV5FU) on cardiac tissues...
Hemostatic effects of atorvastatin versus simvastatinGurhan Kadikoylu
Department of Internal Medicine, Division of Haematology Oncology, Medical School, Adnan Menderes University, Aydin, Turkey
Ann Pharmacother 37:478-84. 2003
..To compare the effects of simvastatin and atorvastatin on hemostatic parameters...
Functional and morphological cardiac changes in myeloproliferative disorders (clinical study)Gurhan Kadikoylu
Department of Hematology, Medical Faculty, Adnan Menderes University, Aydin, Turkey
Int J Cardiol 97:213-20. 2004
..Cardiac involvement is not well defined in myeloproliferative disorders (MPD). The purpose of this study was to evaluate the cardiac involvement by transthoracic echocardiography in MPD...
Gastrointestinal lesions and Helicobacter pylori in patients with myeloproliferative disordersAli O Karaoglu
Gastroenterology Department, Adnan Menderes University Faculty of Medicine, 09100, Aydin, Turkey
Saudi Med J 25:1913-6. 2004
..The aim of this study is to investigate the endoscopic lesions, and Helicobacter pylori (H. pylori) positivity in patients with myeloproliferative disorders (MPD)...
Fludarabine as a second-line treatment of advanced stage chronic lymphocytic leukemiaOrhan Ayyildiz
Department of Hematology-Oncology, Dicle University, Faculty of Medicine, 21100, Diyarbakir, Turkey
Saudi Med J 25:2054-6. 2004
Platelet parameters in women with iron deficiency anemiaGurhan Kadikoylu
Adnan Menderes University Medical Faculty, Division of Hematology, Aydin, Turkey
J Natl Med Assoc 98:398-402. 2006
..Therefore, a relationship between iron metabolism and thrombopoiesis should be considered. The aim of this study was to evaluate the platelet parameters in women with IDA...
Successful treatment of early relapse of ocular myeloma with bortezomib and steroid after autologous stem cell transplantationIrfan Yavasoglu
Adnan Menderes University Medical Faculty, Division of Hematology, Aydin, Turkey
Bratisl Lek Listy 111:670-2. 2010
..Eye findings were recovered after one month. Ocular relapse should be considered if there are ocular findings after ASCT for MM. Bortezomib and steroid may be useful for ocular extramedullary relapse of MM (Fig. 2, Ref. 8)...
Cholesterol levels in patients with multiple myelomaIrfan Yavasoglu
Division of Hematology, Adnan Menderes University Faculty of Medicine, 09100, Aydin, Turkey
Ann Hematol 87:223-8. 2008
..001). Hypocholesterolemia are seen in the patients with MM. Hypocholesterolemia may be due to increased LDL clearance and utilization of cholesterol by myeloma cells...
Is Blastocystis hominis a new etiologic factor or a coincidence in iron deficiency anemia?Irfan Yavasoglu
Division of Hematology, Adnan Menderes University Medical Faculty, Aydin, Turkey
Eur J Haematol 81:47-50. 2008
..Blastocystis hominis may play a role in the development of IDA either on its own or in conjunction with some other agent...
High-dose methylprednisolone therapy in pure red cell aplasiaGurhan Kadikoylu
Department of Internal Medicine, Division of Haematology Oncology, Adnan Menderes University Medical School, Aydin, Turkey
Ann Pharmacother 36:55-8. 2002
..To report our experience using high-dose methylprednisolone (HDMP) treatment in a patient with primary acquired pure red cell aplasia (PRCA) who failed to respond to conventional prednisone therapy...
Spondylodiscitis and Streptoccus viridans endocarditisIrfan Yavasoglu
Adnan Menderes University Medical School, Department of Internal Medicine, Division of Hematology, Aydin, Turkey
J Natl Med Assoc 97:1722-4. 2005
..L4-5 spondylodiscitis was revealed on the lumbar magnetic resonance imaging. He responded to antibiotic treatment. Infective endocarditis should be considered in patients with fever and low-back pain due to spondylodiscitis...
Extravasation of paclitaxel into breast tissue from central catheter portSabri Barutca
Adnan Menderes University Hospital, Department of Haematology Oncology, Aydin, Turkey
Support Care Cancer 10:563-5. 2002
..Extravasation of vesicant drugs from CCP can cause tissue necrosis; it is therefore essential that ports be carefully assessed and used by experienced staff to lessen the likelihood of such an unpleasant complication...
Takayasu arteritis with intracranial involvement mimicking epilepsy: case report and review of the literatureZahit Bolaman
Division of Hematology, Adnan Menderes University Medical Faculty, Turkey
Intern Med 50:1345-8. 2011
..During the control period she had no convulsion. In young patients TA should be kept in mind as a rare cause in convulsion etiology. Intracranial involvement of TA must be evaluated especially if there is a headache and convulsion...
Treatment of solitary gastric carcinoid tumor by endoscopic polypectomy in a patient with pernicious anemiaGurhan Kadikoylu
Adnan Menderes University Medical Faculty, Division of Hematology, 09100 Aydin, Turkey
World J Gastroenterol 12:4267-9. 2006
..Type I gastric carcinoid tumors are only rarely solitary and patients with tumors < 1 cm in size may benefit from endoscopic polypectomy...
MPO-ANCA-associated small vessel vasculitis presenting as fever of unknown origin. Report of one caseHarun Akar
Department of Nephrology, Adnan Menderes University Medical School, Aydin, Turkey
Nephron 92:673-5. 2002
..In a patient presenting with fever of unknown origin, microscopic polyangiitis should also be considered in the differential diagnosis...
[Blastoschizomyces capitatus Fungemia: Three Case Reports and Review of the Literature]Berna Gultekin
Adnan Menderes University Medicine and Health Sciences Center Research and Practice Hospital, Department of Medical Microbiology, Aydin, Turkey
Mikrobiyol Bul 46:134-43. 2012
..capitatus should be considered as an important opportunistic pathogen especially in patients with hematologic malignancies. The data of this study demonstrated that the lowest MIC values for B.capitatus strains were with voriconazole...
Asymptomatic pericardial effusion in chronic myelogenous leukemiaGurhan Kadikoylu
Department of Haematology, Adnan Menderes University Medical Faculty, Aydin, Turkey
Leuk Lymphoma 44:723-5. 2003
..In our case the pericardial effusion was probably due to extramedullary haematopoiesis because it improved with chemotherapy. Follow-up with echocardiography was sufficient in this case...
Thrombocytosis in rheumatoid arthritis: JAK2V617F-positive essential thrombocythemiaOzlem Cırpan Ayvaz
Divisions of Hematology, Adnan Menderes University Medical Faculty, 09100 Aydin, Turkey
Rheumatol Int 32:269-71. 2012
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Plasma exchange in severe hypertriglyceridemia a clinical studyGurhan Kadikoylu
Adnan Menderes University Medical Faculty, Division of Hematology, Tip Fakultesi, Ic Hastaliklari AD, Aydin, Turkey
Transfus Apher Sci 34:253-7. 2006
..Hypercholesterolemia and hypertriglyceridemia are independent risk factors for atherosclerotic heart diseases. Moreover acute pancreatitis may occur in patients with severe hypertriglyceridemia...
Recovery of splenic infarction with anti-platelet treatments and platelet-apheresis in polycythemia veraIrfan Yavasoglu
Adnan Menderes University Medical Faculty, Division of Hematology, Aydin, Turkey
Transfus Apher Sci 34:199-202. 2006
..Splenic infarction may be the first evidence of thrombosis in PV. The reduction of platelet counts with platelet-apheresis, anti-platelet drugs, and careful clinical observation may be satisfactory in the treatment of splenic infarction...
Polycystic ovary syndrome and prolactinoma associationIrfan Yavasoglu
Adnan Menderes University Medical Faculty, Aydin, Turkey
Intern Med 48:611-3. 2009
..After six months of bromocriptine treatment her prolactin level was normal and no adenoma was detected in pituitary MRI. PCOS and prolactinoma association should be taken into account in PCOS cases with mild hyperprolactinoma...
Hereditary thrombophilic factors in stroke due to cerebral infarctZahit Bolaman
Department of Hematology, Adnan Menderes University, Faculty of Medicine, Aydin, Turkey
Am J Med Sci 337:11-3. 2009
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Proinflammatory cytokine levels in hyperthyroidismTaskin Senturk
Department of Immunology, Medical School of Adnan Menderes University, Aydin, Turkey
Clin Invest Med 26:58-63. 2003
..We studied serum levels of osteotrophic cytokines including interlukin (IL)-1, IL-6, IL-8 and tumour necrosis factor alpha (TNF-alpha) in patients with various hyperthyroid states...
Evaluation of smoking as a risk factor for activated protein C resistance during pregnancySamet Kafkas
Department of Obstetrics and Gynecology, Adnan Menderes, University School of Medicine, Aydin, Turkey
Gynecol Obstet Invest 64:89-94. 2007
..The frequency of acquired APC resistance (APCR) in the smoking and non-smoking subjects with normal follow-up of pregnancy and the outcome observed in these two groups were documented...
The spectrum of diseases causing fever of unknown origin in Turkey: a multicenter studyYasar Kucukardali
Department of Internal Medicine, GATA Haydarpasa Hospital, Istanbul, Turkey
Int J Infect Dis 12:71-9. 2008
..The purpose of this trial was to determine the spectrum of diseases with fever of unknown origin (FUO) in Turkey...
Brucellar orchitis in Innerwest Anatolia Region of Turkey. A report of 12 casesGurhan Kadikoylu
Department of Internal Medicine, Adnan Menderes University Medical School, Aydin, Turkey
Urol Int 69:33-5. 2002
..Relapse did not occur again. Conclusively, brucellosis must be considered as a cause of orchitis in especially endemic regions where cattle dealing is widespread. The patients must be followed for relapse during at least 1 year...
Localized extramedullary relapse after autologous hematopoietic stem cell transplantation in multiple myelomaMuhan Erkus
Pathology Department, Medical Faculty, Adnan Menderes University, Aydin 09100, Turkey
Saudi Med J 26:989-91. 2005
..Aspiration smears of lymph node revealed a population of plasmacytoid cells at various stages of maturation. The patient was successfully treated with local radiotherapy and has remained progression-free for more than 20 months...
Non-Hodgkin's lymphoma presenting as a giant chest wall massSabri Barutca
Leuk Lymphoma 44:1635-6. 2003
Effects of simvastatin and atorvastatin in hypercholesterolemic patientsZahit Bolaman
Clin Ther 25:2631-3. 2003
Prothrombin G20210A gene mutation with LightCycler polymerase chain reaction in venous thrombosis and healthy population in the southeast of TurkeyOrhan Ayyildiz
Department of Hematology Oncology, University of Dicle, 21280, Diyarbakir, Turkey
Heart Vessels 19:164-6. 2004
..We showed that this method may be used safely for detection of the PT G20210A gene mutation, and the prevalence of PT G20210A mutation is significantly higher in patients with VT than in the healthy population in the southeast of Turkey...
Treating hypertriglyceridemiaIrfan Yavasoglu
CMAJ 177:603-4; author reply 604-5. 2007
Factor V Leiden G1691A, prothrombin G20210A, and MTHFR C677T mutations in Turkish inflammatory bowel disease patientsMehmet Hadi Yasa
Department of Gastroenterology, Medical School, Adnan Menderes University Aydin, Turkey
Hepatogastroenterology 54:1438-42. 2007
..We investigated the incidence of factor V Leiden G1691A, methylene tetrahydrofolate reductase (MTHFR) C677T, and prothrombin G20210A mutation in 27 Turkish IBD patients with no history of thromboembolic disease...