Adaptive changes in neonatal hormonal and metabolic profiles induced by fetal growth restrictionJacques Beltrand
Institut National de la Santé et de la Recherché Médicale Unit 690, 48 Boulevard Serurier, 75019 Paris, France
J Clin Endocrinol Metab 93:4027-32. 2008
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Resistance to leptin-replacement therapy in Berardinelli-Seip congenital lipodystrophy: an immunological originJacques Beltrand
Unité INSERM U690, Hopital Robert Debre, 48 Boulevard Serurier, Paris, France
Eur J Endocrinol 162:1083-91. 2010
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Catch-up growth following fetal growth restriction promotes rapid restoration of fat mass but without metabolic consequences at one year of ageJacques Beltrand
INSERM, U690, Paris, France
PLoS ONE 4:e5343. 2009
..However, the link between fetal and early postnatal growth and the associated anthropometric and metabolic changes have been poorly studied...
Bone mineral content at birth is determined both by birth weight and fetal growth patternJacques Beltrand
INSERM U690, Hopital Robert Debre, Paris, FR 75019, France
Pediatr Res 64:86-90. 2008
..05). In multivariate analysis, FGR and SGA were significant and independent predictors of low BMC. In conclusion, fetal growth pattern affects BMC not only in SGA infants but also when birth weight is maintained in the normal range...
Metabolic correction induced by leptin replacement treatment in young children with Berardinelli-Seip congenital lipoatrophyJacques Beltrand
Universite Paris 7, INSERM U690, Paris, France
Pediatrics 120:e291-6. 2007
..The objective of this study was to test safety and efficacy of recombinant-methionyl-human leptin replacement in children with Berardinelli-Seip syndrome before development of severe metabolic disease..
Pathophysiology of insulin resistance in subjects born small for gestational ageJacques Beltrand
INSERM, U690, Paris, FR 75019, France Université Paris 7, Paris, FR 75205 cedex 13, France
Best Pract Res Clin Endocrinol Metab 22:503-15. 2008
..The relative impact of early postnatal events in relation to fetal growth has to be considered for designing health policy strategies for early interventions aimed at decreasing disease risk throughout life...
Pathophysiology of insulin resistance in small for gestational age subjects: a role for adipose tissue?Jacques Beltrand
INSERM, U690 and Université Paris 7 Denis Diderot, Paris, France
Endocr Dev 19:73-83. 2010
..The relative impact of early postnatal events in relation to fetal growth has to be considered for designing health policy strategies for early interventions aimed at decreasing the diseases risk throughout life...
Lower insulin secretory response to glucose induced by artificial nutrition in children: prolonged and total parenteral nutritionJacques Beltrand
INSERM, U690, Paris, 75019, France
Pediatr Res 62:624-9. 2007
..These data emphasize that metabolic conditions induced by TPN can lead to lower insulin secretory response to glucose. Patients who remain dependent on TPN are at risk of developing glucose tolerance disorders...
Insulin allergy and extensive lipoatrophy in child with type 1 diabetesJacques Beltrand
Inserm U 690 Diabète de l enfant et développement, Robert Debre Hospital, Paris, France
Horm Res 65:253-60. 2006
..It is suggested that familial disorders of immune cell functions with abnormal and excessive cytokine production might explain these adverse effects triggered by insulin with severe allergic reactions and lipoatrophy...