Research Topics
Genomes and GenesSpecies | S SaussezSummaryAffiliation: University of Mons-Hainaut Country: Belgium Publications
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Detail Information
Publications
Toward functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamsterSven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Avenue du Champ de Mars, 6 Pentagone 1B, 7000 Mons, Belgium
Histochem Cell Biol 123:29-41. 2005..Our data document the presence and differential regulation of galectins in the course of renal tumorigenesis in the model of DES-induced SHKT...- Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomasS Saussez
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Histopathology 52:483-93. 2008..To examine the level of expression of the pleiotropic regulators galectins-1 and -7 in relation to neoplastic progression of hypopharyngeal (HSCCs) and laryngeal (LSCCs) squamous cell carcinomas... - Importance of clinical and radiological follow-up in head and neck cancersS Saussez
Department of Otolaryngology, Head and Neck Surgery, CHU Saint Pierre, Brussels, Belgium
B-ENT 3:179-84. 2007.... - Serum galectin-1 and galectin-3 levels in benign and malignant nodular thyroid diseaseSven Saussez
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Thyroid 18:705-12. 2008..The goal of this study was to determine if a difference in galectin serum levels could be detected between benign and malignant nodular thyroid diseases... - Galectin-3 upregulation during tumor progression in head and neck cancerSven Saussez
Laboratory of Anatomy, University of Mons Hainaut, Mons, Belgium
Laryngoscope 118:1583-90. 2008..To examine the level of expression of galectin-3 in relation to neoplastic progression of hypopharyngeal squamous cell carcinomas (HSCCs) and laryngeal squamous cell carcinomas (LSCCs)... - The determination of the levels of circulating galectin-1 and -3 in HNSCC patients could be used to monitor tumor progression and/or responses to therapySven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Oral Oncol 44:86-93. 2008..01) higher than in sera from the patients with localized tumors. The determination of circulating levels of galectin-1 and -3 could be used to monitor the progression of their disease or their response to therapy... - Second branchial cyst in the parapharyngealspace: a case reportS Saussez
Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint Pierre, 322 rue Haute, 1000 Brussels, Belgium
Auris Nasus Larynx 36:376-9. 2009..We report the clinical findings and management of a large retro- and parapharyngeal branchial cyst in a 54-year-old man whose only complaint was a 12-month history of snoring... - [Bisphosphonates and osteonecrosis of the jaw]S Saussez
Service d anatomie, Faculte de Medecine et de Pharmacie, Universite de Mons Hainaut, Mons, Belgique
Rev Stomatol Chir Maxillofac 109:367-73. 2008..The pathogenesis, predisposing factors, symptoms, and clinical evaluation of this particular necrosis are described. Preventive and therapeutic managements are suggested... - Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7Sven Saussez
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, B 7000 Mons, Belgium
Int J Oncol 34:433-9. 2009..Moreover, it indicated associations between MMP-9 and multifunctional galectins-1 and -7 in situ... - Bisphosphonate-related osteonecrosis of the jaw and its associated risk factors: a Belgian case seriesSven Saussez
Department of Oto Rhino Laryngology, Universite Libre de Bruxelles, Brussel, Belgium
Laryngoscope 119:323-9. 2009..Our purpose is to describe the clinical presentation of 34 cases of BROJ and to identify potential risk factors... - Aggressive pilomatrixoma of the infra-auricular area: a case reportSven Saussez
Department of Otolaryngology Head and Neck Surgery, CHU Saint Pierre, Universite Libre de Bruxelles, Brussels, Belgium
Auris Nasus Larynx 32:407-10. 2005..We report the case of a 15-year-old Turkish boy suffering from an aggressive pilomatrixoma of the infra-auricular region and review the literature about this unclear entity... - Towards functional glycomics by localization of binding sites for tissue lectins: lectin histochemical reactivity for galectins during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamsterSven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Avenue du Champ de Mars, 6 Pentagone 1B, 7000, Mons, Belgium
Histochem Cell Biol 126:57-69. 2006.... - Adhesion/growth-regulatory tissue lectin galectin-1 in relation to angiogenesis/lymphocyte infiltration and prognostic relevance of stromal up-regulation in laryngeal carcinomasSven Saussez
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Anticancer Res 29:59-65. 2009..Galectin-1 has been found to modulate lymphocyte invasion in inflammation and to be involved in angiogenesis in models, thus prompting examination of its clinical relevance in laryngeal cancer... - Galectin fingerprinting in Warthin's tumors: lectin-based approach to trace its origin?Sven Saussez
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Histol Histopathol 25:541-50. 2010..Besides defining the galectin histochemical parameters in Warthin's tumors this study adds support to the hypothesis of heterotopia... - Non-traumatic myositis ossificans in the paraspinal musclesSven Saussez
Department of Otolaryngology and Head and Neck Surgery, Hôpital Saint Pierre, Universite Libre de Bruxelles, 1000, Brussels, Belgium
Eur Arch Otorhinolaryngol 263:331-5. 2006..The diagnosis could only be established after surgery and histological examination. We present a review of the literature on this subject and discuss some related features (radiological and histological)... - Clinically unsuspected tonsillar sarcoidosis in a child revealed by routine histologic examinationSven Saussez
Department of Otolaryngology Head and Neck Surgery, Hôpital Saint Pierre, Universite Libre de Bruxelles, Rue Haute 322, 1000 Bruxelles, Belgium
Int J Pediatr Otorhinolaryngol 70:155-8. 2006..Our observation illustrates the benefit of histological analysis in every tonsillectomy and adenoïdectomy specimen... - Galectin-8 up-regulation during hypopharyngeal and laryngeal tumor progression and comparison with galectin-1, -3 and -7Stéphanie Cludts
Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Pentagone 1B Avenue du Champ de Mars, 6, B 7000 Mons, Belgium
Anticancer Res 29:4933-40. 2009.... - Acromegaly presented as a cause of laryngeal dyspneaS Saussez
Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint Pierre, Brussels, Belgium
Auris Nasus Larynx 34:541-3. 2007..Vocal cord fixation is probably due to hypopharyngeal and laryngeal soft tissue swelling and can be reversible after successful treatment of the adenoma... - Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancerSven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Avenue du Champ de Mars 6, Pentagone 1B, B 7000, Mons, Belgium
Ann Surg Oncol 13:999-1009. 2006.... - Mediastinal tracheostomy: unilateral resection of the anterior chest wallT Lequeux
ENT Department, CHU Saint Pierre, Brussels, Belgium
J Laryngol Otol 119:903-5. 2005..Nowadays, with the possibility of various pedicled flaps, bilateral resection no longer seems to be necessary. This unilateral resection leads to a reduction in post-operative sequelae... - Bisphosphonate-induced osteonecrosis of the jaw: a review of 2,400 patient casesO Filleul
Faculty of Medicine and Pharmacy, Department of Anatomy and Cellular Biology, University of Mons, Pentagone 2C Avenue du Champ de Mars, 6, B 7000, Mons, Belgium
J Cancer Res Clin Oncol 136:1117-24. 2010..Osteonecrosis of the jaw, however, can occur during treatment. This complication is poorly understood and is called "bisphosphonate-induced osteonecrosis of the jaw" (BIOJ)... - Increased expression of macrophage migration inhibitory factor during progression to hypopharyngeal squamous cell carcinomaStéphanie Cludts
Laboratory of Anatomy and Cellular Biology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Anticancer Res 30:3313-9. 2010..To examine the presence of macrophage migration inhibitory factor (MIF) quantitatively in relation to neoplastic progression of hypopharyngeal squamous cell carcinoma (HSCC)... - Galectins as modulators of tumor progression in head and neck squamous cell carcinomasSven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Belgium
Head Neck 29:874-84. 2007..The present review details the involvement of galectins in HNSCC biology and suggests a number of approaches to reduce the levels of expression of galectin-1 in HNSCCs, with the aim of improving the efficiency of HNSCC immunotherapy... - [Involvement of human papillomavirus in upper aero-digestive tracts cancers]P Ernoux Neufcoeur
Service d Anatomie et de Biologie Cellulaire, Universite de Mons Hainaut, 20 Place du Parc, B 7000 Mons, Belgique, Service d Anatomopathologie, Universite de Liege, Place du 20 Août 9, 4000 Liege, Belgique
Bull Cancer 96:941-50. 2009..New studies regarding HPV status in HNSCCs are warranted to provide a rationale for large scale HPV vaccination in young male populations... - Variable-field relaxometry of iron-containing human tissues: a preliminary studyAline Hocq
Biological Physics Department, University of Mons Hainaut, 7000 Mons, Belgium
Contrast Media Mol Imaging 4:157-64. 2009..The value of 1/T(2) at high field could be used to evaluate iron accumulation in vivo. In the future, confirmation of those features is expected to be achieved from measurements of fresh (not embalmed) human tissues... - The helicase-like transcription factor is a strong predictor of recurrence in hypopharyngeal but not in laryngeal squamous cell carcinomasAurelie Capouillez
Laboratories of Anatomy, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Histopathology 55:77-90. 2009.... - High level of galectin-1 expression is a negative prognostic predictor of recurrence in laryngeal squamous cell carcinomasSven Saussez
Laboratory of Histology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Mons, Belgium
Int J Oncol 30:1109-17. 2007..It has the potential to identify patients unlikely to benefit from T-cell-mediated immunotherapy, although the definitive effector function from its pro- and antitumoral activity profile has not been delineated... - [Cancer of the upper aero-digestive tract: elevated incidence in Belgium, new risk factors and therapeutic perspectives]S Saussez
Laboratoire d Anatomie et de Biologie cellulaire, Faculte de Medecine et de Pharmacie, Universite de Mons, Belgique
Bull Mem Acad R Med Belg 165:453-61; discussion 462-3. 2010..New studies regarding HPV status in HNSCCs are warranted to provide a rationale for large scale HPV vaccination in young male populations... - Maxillary sinusitis caused by the migration of a silastic implant used for an orbital floor reconstruction: a case reportS Saussez
Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint Pierre, 322 rue Haute, 1000 Brussels, Belgium
B-ENT 6:299-301. 2010..The authors report on a patient whose unilateral chronic maxillary sinusitis was caused by the migration of a silastic implant used for orbital floor repair... - Helicase-like transcription factor exhibits increased expression and altered intracellular distribution during tumor progression in hypopharyngeal and laryngeal squamous cell carcinomasAurelie Capouillez
Faculty of Medicine and Pharmacy, University of Mons Hainaut, Pentagone 1B Avenue du Champ de Mars, 6, 7000, Mons, Belgium
Virchows Arch 453:491-9. 2008..0007). Our data reveal an association between the presence of HLTF and neoplastic progression of hypopharyngeal and laryngeal SCCs... - [Hard palate B cell lymphoma with spontaneous regression]P Brachet
Service d Oto Rhino Laryngologie et de Chirurgie Cervico faciale, CHU Saint Pierre, Brussels, Belgium
Rev Stomatol Chir Maxillofac 112:180-2. 2011..Non-Hodgkin lymphomas are common cancers that can develop in the upper aero-digestive tract. We describe a case of a large B-cell palatine lymphoma with spontaneous clinical regression... - A comparison of survival lifetime of the Provox and the Provox2 voice prosthesisT Lequeux
Department of ENT, CHU Saint Pierre, Brussels, Belgium
J Laryngol Otol 117:875-8. 2003..This could be due to the difference in elasticity of these valves that could lead to a different level of colonization and invasion of the valves by micro-organisms... - Different presentations of ophthalmic aspergillosisF Willermain
Ophthalmology, CHU Saint Pierre, Universite Libre de Bruxelles, Bruxelles Belgium
Eur J Ophthalmol 18:827-30. 2008..However, when the immune system is compromised, it can invade many organs and be responsible for severe disease. The authors present cases with both classical and atypical features of ophthalmic aspergillosis... - The helicase-like transcription factor and its implication in cancer progressionG Debauve
Laboratory of Molecular Biology, Faculty of Medicine and Pharmacy, University of Mons Hainaut, Pentagone 3A Avenue du Champ de Mars, 6, B 7000, Mons, Belgium
Cell Mol Life Sci 65:591-604. 2008..Those apparently contradictory observations suggest that HLTF might play various roles in cancer. In this review, we will try to reconcile all these data in order to specify the role of HLTF in cancer progression... - Galectin-7S Saussez
Laboratory of Histology, and Laboratory of Anatomy, Faculty of Medicine and Pharmacy, University of Mons-Hainaut, UMH, Mons, Belgium
Cell Mol Life Sci 63:686-97. 2006..Defects in apoptosis constitute one of the major hallmarks of human cancers, and galectin-7 can act as either a positive or a negative regulatory factor in tumour development, depending on the histological type of the tumour... - High incidence of sensitization to ornamental plants in allergic rhinitisV Mahillon
Clinic of ENT, Saint-Pierre University Hospital, Free University of Brussels, Brussels, Belgium
Allergy 61:1138-40. 2006..CONCLUSION: In allergic rhinitis, indoor plants should be considered as potential allergens... - Schwannoma of the accessory phrenic nerveGersende De Bie
Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint Pierre, Brussels, Belgium
Am J Otolaryngol 28:357-9. 2007..We describe the first case of a cervical schwannoma involving the accessory phrenic nerve. The anatomy and function of the accessory phrenic nerve are reviewed... - Reconstruction of circumferential oro- and hypopharyngeal defects with U-shaped pectoralis major myocutaneous flapSven Saussez
Department of Otorhinolaryngology Head and Neck Surgery, CHU Saint Pierre, Bruxelles, Belgium
Otolaryngol Head Neck Surg 134:823-9. 2006..The purpose of the study was to evaluate the effectiveness of a U-shaped pectoralis major myocutaneous flap (PMMF) to reconstruct a large circumferential defect involving the oro- and hypopharynx... - In vivo assessment of temozolomide local delivery for lung cancer inhalation therapyNathalie Wauthoz
Laboratoire de Pharmacie Galénique et de Biopharmacie, Institut de Pharmacie, Universite Libre de Bruxelles, Boulevard du Triomphe, CP207, 1050 Brussels, Belgium
Eur J Pharm Sci 39:402-11. 2010..This inhalation delivery could be used to deliver other types of anticancer drugs... - Congenital transsphenoidal meningocele: case report and review of the literatureCatherine Blaivie
Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint-Pierre, Brussels, Belgium
Am J Otolaryngol 27:422-4. 2006..We report a case of sphenoidal meningocele treated using an endoscopic procedure and review the literature regarding its congenital origin... - In reference to quantitative analysis of syndecan-1 expression in dysplasia and squamous cell carcinoma of the oral cavitySven Saussez
Laryngoscope 118:944-5; author reply 945. 2008