Research Topics
| Johan RobbensSummaryAffiliation: University of Antwerp Country: Belgium Publications
| Collaborators
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Detail Information
Publications
Ecotoxicological risk assessment using DNA chips and cellular reportersJohan Robbens
Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171 B 2020, Antwerp, Belgium
Trends Biotechnol 25:460-6. 2007..Some important technical and interpretative hurdles still need to be overcome before a full implementation of ecotoxicogenomics in regulatory settings will occur...- Performance of the flow cytometric E-screen assay in screening estrogenicity of pure compounds and environmental samplesCaroline Vanparys
Laboratory of Ecophysiology, Biochemistry and Toxicology, University of Antwerp, Antwerp, Belgium
Sci Total Environ 408:4451-60. 2010..Therefore, this study, among other E-screen studies, supports the use of MCF-7 cell proliferation as estrogenicity screen for pure compounds and complex samples... - cDNA phage display as a novel tool to screen for cellular targets of chemical compoundsBieke Van Dorst
Department of Biology, Laboratory for Ecophysiology, University Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Toxicol In Vitro 24:1435-40. 2010.... - In vitro selection and characterization of DNA aptamers recognizing chloramphenicolJaytry Mehta
University of Antwerp, Department of Biology, Laboratory for Ecophysiology, Biochemistry and Toxicology, Groenenborgerlaan, Antwerp, Belgium
J Biotechnol 155:361-9. 2011..8 and 1?M respectively). These aptamers open up possibilities to allow easy detection of Cam via aptamer-based biosensors... - Selection and characterization of PCB-binding DNA aptamersJaytry Mehta
Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Anal Chem 84:1669-76. 2012..This study therefore advances aptamer technology by targeting one of the highly sought-after POPs, for the first time ever recorded... - Phage display as a novel screening tool for primary toxicological targetsBieke Van Dorst
Department of Biology, Laboratory for Ecophysiology, Biochemistry and Toxicology, University Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Environ Toxicol Chem 29:250-5. 2010..This shows that phage display, which is already widely used in other research fields, also has potential in ecotoxicology, as a novel screening tool with which to determine primary toxicological targets of chemical compounds... - Recent advances in recognition elements of food and environmental biosensors: a reviewBieke Van Dorst
University of Antwerp, Department of Biology, Laboratory of Ecophysiology, Biochemistry and Toxicology, Groenenborgerlaan 171, 2020 Antwerp, Belgium
Biosens Bioelectron 26:1178-94. 2010.... - Cadmium and zinc induction of ZnT-1 mRNA in an established carp cell lineFrederik Muylle
Department of Biology, Laboratory for Ecophysiology, Biochemistry and Toxicology, University of Antwerp, Belgium
Comp Biochem Physiol C Toxicol Pharmacol 143:242-51. 2006..Our results clearly show that although Zn and Cd can both regulate Zn export in EPC cells, the effects on the cellular Zn pools are quite different... - Effect of copper exposure on gene expression profiles in Chlamydomonas reinhardtii based on microarray analysisAn Jamers
Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
Aquat Toxicol 80:249-60. 2006.... - Expression characteristics of potential biomarker genes in Tra catfish, Pangasianodon hypophthalmus, exposed to trichlorfonAmit Kumar Sinha
Laboratory for Ecophysiology, Biochemistry and Toxicology, University of Antwerp, 2020 Antwerp, Belgium
Comp Biochem Physiol Part D Genomics Proteomics 5:207-16. 2010..These results could permit to develop a "molecular biomarker system" which can be applied as a first-tier method of identifying contaminant exposure before effects at population level occur... - The identification of cellular targets of 17? estradiol using a lytic (T7) cDNA phage display approachBieke Van Dorst
University Antwerp, Department of Biology, Antwerp, Belgium
Toxicol In Vitro 25:388-93. 2011..This illustrates the potential of lytic (T7) cDNA phage display in toxicology, to provide important information about cellular targets of chemical compounds... - Ecological impact assessment of metallurgic effluents using in situ biomarker assaysWim De Coen
Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Environ Pollut 141:283-94. 2006..In addition, we found clear genotoxic effects caused by the industrial discharges that might correlate with a reduction in (long-term) survival... - Folding properties of the hepatitis B core as a carrier protein for vaccination researchMichiel Etienne Janssens
Department of Animal Health, Institute for Tropical Medicine, 155 Nationalestraat, 2000, Antwerp, Belgium
Amino Acids 38:1617-26. 2010..In this study, we also propose a new high-yield purification protocol for fusion proteins to be used in vaccination experiments with the carrier protein or in comparative studies of particulate or non-particulate HBc fusion proteins... - Estrogen-like properties of fluorotelomer alcohols as revealed by mcf-7 breast cancer cell proliferationMarleen Maras
Laboratory for Ecophysiology, Biochemistry, and Toxicology, University of Antwerp, Antwerp, Belgium
Environ Health Perspect 114:100-5. 2006..The latter finding suggests an alternative mode of action of the fluorotelomer alcohols compared with that of E2. This study clearly underlines the need for future in vivo testing for specific endocrine-related end points... - Expression, purification and characterization of full-length RNA-free hepatitis B core particlesKatleen Broos
Laboratory of Plant Physiology, Department of Biology, 171 Groenenborgerlaan, Building U, 6th Floor, CGB University of Antwerp, 2020 Antwerpen, Belgium
Protein Expr Purif 54:30-7. 2007..In this report, we detail a novel method for the synthesis and purification of full-length core particles essentially free of RNA from Escherichia coli... - Conventional and (eco) toxicological assessment of batch partial ozone oxidation and subsequent biological treatment of a tank truck cleaning generated concentrateWim De Schepper
University of Antwerp UA, Department of Biology, Ecophysiology, Biochemistry and Toxicology Group EBT, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Water Res 43:4037-49. 2009..subcapitata algal 72h growth inhibition test. The 500 mg O(3)/l optimal ozone dosage, as determined from P. subcapitata algal 72h growth inhibition and S(COD) removal, could be retrieved using short-term methods... - Response of DNA fragments to potentiometric sensors studied using HPLCLuc J Nagels
Antwerp University, Chemistry Department, Groenenborgerlaan 171, B 2020, Antwerp, Belgium
Comb Chem High Throughput Screen 10:555-9. 2007..The slopes of the calibration graphs were at least 23 mV/decade (dT(10)), which was much higher than expected. The results are discussed in view of the potential use of this sensor type in high throughput microarrays... - Toxicity ranking and toxic mode of action evaluation of commonly used agricultural adjuvants on the basis of bacterial gene expression profilesIngrid Nobels
Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Antwerp, Belgium
PLoS ONE 6:e24139. 2011..Although the number of compounds that were evaluated is rather limited (13), the results show that the used reporter assay is a promising tool to rank commonly used agricultural adjuvants based on toxicity and toxic mode of action data...