Research Topics
| Jo NijsSummaryAffiliation: University College of Antwerp Country: Belgium Publications
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Detail Information
Publications
Clinical assessment of scapular positioning in patients with shoulder pain: state of the artJo Nijs
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, University College Antwerp, Belgium
J Manipulative Physiol Ther 30:69-75. 2007
From acute musculoskeletal pain to chronic widespread pain and fibromyalgia: application of pain neurophysiology in manual therapy practiceJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussels, Belgium
Man Ther 14:3-12. 2009..III) However, manual therapists ignoring the processes involved in the development and maintenance of chronic widespread pain/FM may cause more harm then benefit to the patient by triggering or sustaining central sensitisation...
Can exercise limits prevent post-exertional malaise in chronic fatigue syndrome? An uncontrolled clinical trialJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Clin Rehabil 22:426-35. 2008..It was hypothesized that the use of exercise limits prevents symptom increases and worsening of their health status following a walking exercise in people with chronic fatigue syndrome...
Chronic fatigue syndrome: an approach combining self-management with graded exercise to avoid exacerbationsJo Nijs
Division of Musculoskeletal Physiotherapy, Department of Health Care Sciences, University College Antwerp, Vrije Universiteit Brussel, Belgium
J Rehabil Med 40:241-7. 2008....
Recruitment bias in chronic pain research: whiplash as a modelJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
Clin Rheumatol 30:1481-9. 2011..In order to enhance the external validity of study findings, chronic WAD studies should combine a variety of recruitment procedures...
Pain neurophysiology education improves cognitions, pain thresholds, and movement performance in people with chronic whiplash: a pilot studyJessica Van Oosterwijck
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
J Rehabil Res Dev 48:43-58. 2011....
Exercise performance and chronic pain in chronic fatigue syndrome: the role of pain catastrophizingJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit, Brussels, Belgium
Pain Med 9:1164-72. 2008....
Unravelling intracellular immune dysfunctions in chronic fatigue syndrome: interactions between protein kinase R activity, RNase L cleavage and elastase activity, and their clinical relevanceMira Meeus
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
In Vivo 22:115-21. 2008..RNase L and elastase activity are related to daily functioning, thus evidence supporting the clinical importance of these immune dysfunctions in CFS patients was provided...
In the mind or in the brain? Scientific evidence for central sensitisation in chronic fatigue syndromeJo Nijs
Department of Human Physiology, Vrije Universiteit Brussel VUB, Brussels, Belgium
Eur J Clin Invest 42:203-12. 2012..e. central sensitisation). Since then, several studies have examined central sensitisation in patients with CFS. This study provides an overview of such studies...
Altered breathing patterns during lumbopelvic motor control tests in chronic low back pain: a case-control studyNathalie Roussel
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College of Antwerp, 2170, Merksem, Belgium
Eur Spine J 18:1066-73. 2009..01). Changes in breathing pattern during motor control tests were not related to pain severity (P > 0.01), but were related to motor control dysfunction (P = 0.01)...
Chronic fatigue syndrome: exercise performance related to immune dysfunctionJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
Med Sci Sports Exerc 37:1647-54. 2005..To establish a causal relationship, further study of these interactions using a prospective longitudinal design is required...
Altered lumbopelvic movement control but not generalized joint hypermobility is associated with increased injury in dancers. A prospective studyNathalie Anne Roussel
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College of Antwerp, Belgium
Man Ther 14:630-5. 2009..Neither generalized joint hypermobility, evaluated with the Beighton score, nor a history of LBP was predictive of injuries. Further study of these interactions is required...
Reliability of the assessment of lumbar range of motion and maximal isometric strength in patients with chronic low back painNathalie A Roussel
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, University College of Antwerp, Belgium
Arch Phys Med Rehabil 89:788-91. 2008..To examine the interobserver reliability of the assessment of lumbar range of motion (ROM) and maximal isometric strength in patients with chronic low back pain (CLBP) using commercially available equipment...
Kinesiophobia in chronic fatigue syndrome: assessment and associations with disabilityJo Nijs
Department of Human Physiology, Vrije Universiteit Brussel, Brussel, Belgium
Arch Phys Med Rehabil 85:1586-92. 2004....
Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental studyMira Meeus
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College Antwerp, Merksem, Belgium
J Rehabil Med 42:884-90. 2010....
Pain physiology education improves pain beliefs in patients with chronic fatigue syndrome compared with pacing and self-management education: a double-blind randomized controlled trialMira Meeus
Department of Health Sciences, Artesis University College, Antwerp, Belgium
Arch Phys Med Rehabil 91:1153-9. 2010..To examine whether pain physiology education was capable of changing pain cognitions and pain thresholds in patients with chronic fatigue syndrome (CFS) and chronic widespread pain...
Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practiceJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Man Ther 15:135-41. 2010..The clinical examination used to recognize central sensitization entails the distinction between primary and secondary hyperalgesia...
Can submaximal exercise variables predict peak exercise performance in women with chronic fatigue syndrome?Jo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit, Brussels, Belgium
Arch Med Res 38:350-3. 2007..6+/-11.2% (range 0.1-63.7%). It is concluded that the prediction of VO2PEAK based on VO2SUBMAX might be useful for analyzing group differences or treatment effects but not for individual (clinical) purposes...
Kinesiophobia and symptomatology in chronic fatigue syndrome: a psychometric study of two questionnairesJo Nijs
Department of Human Physiology, Vrije Universiteit Brussel, Brussel, Belgium
Psychol Psychother 81:273-83. 2008....
Scapular positioning and motor control in children and adults: a laboratory study using clinical measuresFilip Struyf
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College Antwerp, Antwerp, Belgium
Man Ther 16:155-60. 2011..In addition, strength and muscular endurance develops from childhood through adolescence. It is not known whether differences in scapular positioning and motor control between adults and children may exist...
Psychometric properties of the Dutch Chronic Fatigue Syndrome--Activities and Participation Questionnaire (CFS-APQ)Jo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Belgium
Phys Ther 83:444-54. 2003..In this study, the convergent validity, content validity, and test-retest reliability of data obtained with the Dutch-language version of the questionnaire were examined...
Can pacing self-management alter physical behavior and symptom severity in chronic fatigue syndrome? A case seriesJo Nijs
Vrije Universiteit Brussel, Building L Mfys, Pleinlaan 2, BE 1050, Brussels, Belgium
J Rehabil Res Dev 46:985-96. 2009..The outcome of the present study calls for a randomized controlled clinical trial to examine the effectiveness of pacing self-management for people with CFS...
Comparison of two exercise testing protocols in patients with chronic fatigue syndromeJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
J Rehabil Res Dev 44:553-9. 2007..Further study is warranted...
Long-term functioning following whiplash injury: the role of social support and personality traitsJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Building L Mfys, Pleinlaan 2, BE 1050, Brussels, Belgium
Clin Rheumatol 30:927-35. 2011..For such studies, a broad view of long-term functioning within the biopsychological model should be applied...
Chronic musculoskeletal pain in patients with the chronic fatigue syndrome: a systematic reviewMira Meeus
Division of Musculoskeletal Physiotherapy, Higher Institute of Physiotherapy, Department of Health Care Sciences, Hogeschool Antwerpen HA, Van Aertselaerstraat 31, 2170 Merksem, Belgium
Eur J Pain 11:377-86. 2007..In addition to debilitating fatigue the majority of patients with chronic fatigue syndrome (CFS) experience chronic widespread pain...
Sensorimotor incongruence triggers sensory disturbances in professional violinists: an experimental studyLiesbeth Daenen
Division of Musculoskeletal Physiotherapy, Faculty of Medicine, University of Antwerp, Antwerp, Belgium
Rheumatology (Oxford) 49:1281-9. 2010....
Scapular positioning in patients with shoulder pain: a study examining the reliability and clinical importance of 3 clinical testsJo Nijs
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Hogeschool, Antwerpen, Antwerp, Belgium
Arch Phys Med Rehabil 86:1349-55. 2005..To examine the interobserver reliability, internal consistency, and clinical importance of 3 clinical tests for the assessment of scapular positioning in patients with shoulder pain...
Breathing retraining in patients with chronic fatigue syndrome: a pilot studyJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit, Brussel, Belgium
Physiother Theory Pract 24:83-94. 2008....
Evidence for generalized hyperalgesia in chronic fatigue syndrome: a case control studyMira Meeus
Department of Health Sciences, Division of Musculoskeletal Physiotherapy, Artesis Hogeschool Antwerpen AHA, Merksem, Belgium
Clin Rheumatol 29:393-8. 2010..These findings provide evidence for the existence of hyperalgesia even in asymptomatic areas (generalized secondary hyperalgesia). The generalized hyperalgesia may represent the involvement of a sensitized central nervous system...
Nociception affects motor output: a review on sensory-motor interaction with focus on clinical implicationsJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Clin J Pain 28:175-81. 2012..Hence, in many cases neither patients nor clinicians are aware of the interaction. It is aimed at reviewing the scientific literature on nociception-motor interaction, with emphasis on clinical implications...
Associations between bronchial hyperresponsiveness and immune cell parameters in patients with chronic fatigue syndromeJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy, Academic Hospital, Vrije Universiteit Brussel, Belgium
Chest 123:998-1007. 2003..To examine whether bronchial hyperresponsiveness (BHR) in patients with chronic fatigue syndrome (CFS) is caused by immune system abnormalities...
Clinical assessment of scapular positioning in musicians: an intertester reliability studyFilip Struyf
University College Antwerp, Antwerp, Belgium
J Athl Train 44:519-26. 2009..Overall, the reliability of the clinical tools used to assess scapular positioning has not been studied in musicians...
Impairments of the 2-5A synthetase/RNase L pathway in chronic fatigue syndromeJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
In Vivo 19:1013-21. 2005..Studies addressing the treatment of the deregulation of the 2-5A synthetase/RNase L pathway in CFS are warranted...
Chronic fatigue syndrome: lack of association between pain-related fear of movement and exercise capacity and disabilityJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy Science, Vrije Universiteit Brussel, Brussels, Belgium
Phys Ther 84:696-705. 2004..The purpose of this study was to examine whether pain-related fear of movement is associated with exercise capacity, activity limitations, or participation restrictions in patients with CFS who experience widespread pain...
Diffuse noxious inhibitory control is delayed in chronic fatigue syndrome: an experimental studyMira Meeus
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, University College Antwerp HA, Belgium
Pain 139:439-48. 2008..In conclusion, delayed pain inhibition may play a role in chronic widespread pain in CFS but further research is required...
Tired of being inactive: a systematic literature review of physical activity, physiological exercise capacity and muscle strength in patients with chronic fatigue syndromeJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Disabil Rehabil 33:1493-500. 2011..Future studies should use a wash-out period for medication use, blinded assessments, a priori power calculation and a sedentary control group comparable for age, gender, body weight, body length and current physical activity level...
Employment status in chronic fatigue syndrome. A cross-sectional study examining the value of exercise testing and self-reported measures for the assessment of employment statusJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Clin Rehabil 19:895-9. 2005..To examine the value of exercise testing and self-reported disability for the assessment of employment status in patients with chronic fatigue syndrome...
Central sensitization in patients with rheumatoid arthritis: a systematic literature reviewMira Meeus
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
Semin Arthritis Rheum 41:556-67. 2012..The goal of the present study is to systematically review the scientific literature addressing central sensitization and central nociceptive processing in patients with rheumatoid arthritis (RA)...
Serotonergic descending inhibition in chronic pain: design, preliminary results and early cessation of a randomized controlled trialMira Meeus
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Building L Mfys, Pleinlaan 2, 1050 Brussels, Belgium
In Vivo 25:1019-25. 2011....
Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control studyMira Meeus
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College Antwerp, Belgium
Arch Phys Med Rehabil 92:1820-6. 2011....
Nitric oxide concentrations are normal and unrelated to activity level in chronic fatigue syndrome: a case-control studyMira Meeus
Division of Musculoskeletal Physiotherapy, Artesis University College AHA, Department of Health Sciences, Van Aertselaerstraat 31, 2170 Merksem, Belgium
In Vivo 24:865-9. 2010..since patients with chronic fatigue syndrome (CFS) often present elevated levels of nitric oxide (NO) and low levels of physical activity, this study aimed at revealing possible correlations between NO concentration and physical activity...
Chronic musculoskeletal pain in chronic fatigue syndrome: recent developments and therapeutic implicationsJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Man Ther 11:187-91. 2006..Studies examining the effectiveness of these strategies for CFS patients are warranted...
The Chronic Fatigue Syndrome Activities and Participation Questionnaire (CFS-APQ): an overviewJo Nijs
Department of Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel VUB, Brussels, Belgium
Occup Ther Int 12:107-21. 2005..50; n = 47). It is concluded that the CFS-APQ generates reliable and valid data, and can be used as a clinical measure of disease severity in patients with CFS. Future studies should aim at examining the sensitivity of the CFS-APQ...
Validity of cross-friction algometry procedure in referred muscle pain syndromes: preliminary results of a new referred pain provocation technique with the aid of a Fischer pressure algometer in patients with nonspecific low back painAndre D Farasyn
Vrije Universiteit Brussel, Brussels, Belgium
Clin J Pain 24:456-62. 2008..The new clinical examination method measures the provoked RP threshold resulting in an outcome, expressed in kg/cm2...
Is the International Physical Activity Questionnaire-short form (IPAQ-SF) valid for assessing physical activity in Chronic Fatigue Syndrome?Mira Meeus
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College Antwerp AHA, Antwerp, Belgium
Disabil Rehabil 33:9-16. 2011..To evaluate the criterion validity and internal consistency of the International Physical Activity Questionnaire-short form (IPAQ-sf) in Chronic Fatigue Syndrome (CFS) patients...
Diagnostic value of five clinical tests in patellofemoral pain syndromeJo Nijs
Division Musculoskeletal Physiotherapy, Department of Health Sciences, Hogeschool Antwerpen, Belgium
Man Ther 11:69-77. 2006..The negative likelihood ratios for all tests exceeded the threshold value of 0.5, suggestive of clinically irrelevant information. These data question the validity of clinical tests for the diagnosis of PFPS...
Low back pain: clinimetric properties of the Trendelenburg test, active straight leg raise test, and breathing pattern during active straight leg raisingNathalie A Roussel
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, University College Antwerp, Belgium
J Manipulative Physiol Ther 30:270-8. 2007..The purpose of this study is to examine the reliability, internal consistency, and clinical importance of 3 clinical tests that analyze motor control mechanisms of the lumbopelvic region in patients with nonspecific LBP...
Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndromeMira Meeus
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel VUB, Brussel, Belgium
Clin Rheumatol 26:465-73. 2007..Further investigations could use similar protocols to those already used in studies on pain in FM like, for example, studies on temporal summation, spatial summation, the role of psychosocial aspects in chronic pain, etc...
Pain in patients with chronic fatigue syndrome: does nitric oxide trigger central sensitisation?Jo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel VUB, Belgium
Med Hypotheses 64:558-62. 2005....
Reliability of the assessment of lumbar range of motion and maximal isometric strengthNathalie Roussel
Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Hogeschool Antwerpen, Merksem, Belgium
Arch Phys Med Rehabil 87:576-82. 2006..To examine the interobserver reliability and intrasubject variability of the assessment of lumbar range of motion (ROM) and maximal isometric strength in asymptomatic subjects by using commercially available equipment...
Lack of endogenous pain inhibition during exercise in people with chronic whiplash associated disorders: an experimental studyJessica Van Oosterwijck
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
J Pain 13:242-54. 2012..This finding highlights the fact that one should be cautious when evaluating and recommending exercise in people with chronic WAD, and that the use of more individual, targeted exercise therapies is recommended...
Primary care physical therapy in people with fibromyalgia: opportunities and boundaries within a monodisciplinary settingJo Nijs
Vrije Universiteit Brussel, Building L Mfys, Pleinlaan 2, BE 1050 Brussels, Belgium
Phys Ther 90:1815-22. 2010..Superior results are to be expected when various treatment components are combined...
Chronic fatigue syndrome: intracellular immune deregulations as a possible etiology for abnormal exercise responseJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy Science, Vrije Universiteit Brussel, Brussel 1090, Belgium
Med Hypotheses 62:759-65. 2004..Finally, it is explored how several types of infections, frequently identified in CFS patients, fit into these hypothetical pathophysiological interactions...
Chronic fatigue syndrome: a risk factor for osteopenia?Jo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussel, Belgium
Med Hypotheses 60:65-8. 2003..IGF-I is critical to the proliferation of osteoblasts. Consequently, depleted levels of IGF-I may shift the balance between osteoclastic and osteoblastic activity towards bone resorption...
Immunological similarities between cancer and chronic fatigue syndrome: the common link to fatigue?Mira Meeus
Department of Health Sciences, Van Aertselaerstraat 31, 2170 Merksem, Belgium
Anticancer Res 29:4717-26. 2009..These anomalies may be part of the physiopathology of some of the common complaints, such as fatigue. Further studies to confirm the hypotheses given here are warranted...
Prediction of peak oxygen uptake in patients fulfilling the 1994 CDC criteria for chronic fatigue syndromeJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physical Therapy and Chronic Fatigue Clinic, Vrije Universiteit Brussel, Belgium
Clin Rehabil 18:785-92. 2004..To establish an inexpensive, simple method of predicting peak oxygen uptake (VO2peak) in patients fulfilling the 1994 Centers for Disease Control and Prevention (CDC) criteria for chronic fatigue syndrome (CFS)...
How to explain central sensitization to patients with 'unexplained' chronic musculoskeletal pain: practice guidelinesJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
Man Ther 16:413-8. 2011..Pain physiology education is a continuous process initiated during the educational sessions and continued within both the active treatment and during the longer term rehabilitation program...
Rehabilitation of chronic whiplash: treatment of cervical dysfunctions or chronic pain syndrome?Jo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Building L Mfys, Pleinlaan 2, 1050 Brussels, Belgium
Clin Rheumatol 28:243-51. 2009..It is recommended to prevent sensorimotor incongruence, target cognitive-emotional sensitization, and apply a cognitive behavioral therapy-guided exercise program...
Intracellular immune dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome: state of the art and therapeutic implicationsJo Nijs
Vrije Universiteit Brussel, Faculty of Physical Education and Physiotherapy, Department of Human Physiology, Building L, Pleinlaan 2, 1050 Brussels, Belgium
Expert Opin Ther Targets 12:281-9. 2008..Evidence in support of intracellular immune dysfunctions in people with myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is accumulating, but few studies have addressed intracellular immunity as a potential therapeutic target...
High prevalence of Mycoplasma infections among European chronic fatigue syndrome patients. Examination of four Mycoplasma species in blood of chronic fatigue syndrome patientsJo Nijs
Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, KRO Gebouw 1, Laarbeeklaan 101, 1090 Brussel, Belgium
FEMS Immunol Med Microbiol 34:209-14. 2002..2%). Compared to American CFS patients (M. pneumoniae>M. hominis>M. penetrans), a slightly different pattern of mycoplasmal infections was found in European CFS patients (M. hominis>M. pneumoniae, M. fermentansz.Gt;M. penetrans)...
Nitric oxide and chronic fatigue syndrome: Are we caring for our patients or are we practicing selfcare?Jo Nijs
Med Hypotheses 66:449-50. 2006
Oxidative stress might reduce essential fatty acids in erythrocyte membranes of chronic fatigue syndrome patientsJo Nijs
Nutr Neurosci 7:251-3. 2004
Generalized joint hypermobility is more common in chronic fatigue syndrome than in healthy control subjectsJo Nijs
Department of Human Physiology Faculty of Physical Education and Physiotherapy Vrije Universiteit Brussel VUB, Belgium
J Manipulative Physiol Ther 29:32-9. 2006....
Statistics and pain-related fear measures in acute low back painJo Nijs
Man Ther 9:45-6; author reply 47-8. 2004
