Research Topics
| N MassagerSummaryCountry: Belgium Publications
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Detail Information
Publications
Gamma knife radiosurgery for brainstem arteriovenous malformations: preliminary resultsN Massager
Gamma Knife Center, H pital Erasme, Brussels, Belgium
J Neurosurg 93:102-3. 2000..This study was undertaken to assess the efficacy and safety of gamma knife radiosurgery (GKS) for the treatment of arteriovenous malformations (AVMs) located within the brainstem...
Experimental analysis of radiation dose distribution in radiosurgery: I. Dose hot spot inside target volumeNicolas Massager
Gamma Knife Center, Department of Neurosurgery, University Hospital Erasme, Brussels, Belgium
Stereotact Funct Neurosurg 87:82-7. 2009..Here, we aimed to study histological consequences of different dose distributions inside the target area in an experimental model of Gamma Knife irradiation in the rat striatum...
[Surgical treatment of movement disorders]N Massager
Clinique de Neurochirurgie Stéréotaxique et Fonctionnelle, Service de Neurochirurgie, Hopital Erasme, Bruxelles
Rev Med Brux 29:248-51. 2008..The major indications of these surgical techniques are Parkinson's disease, essential tremor, dystonia, Huntington's disease and tremor in multiple sclerosis...
Influence of nerve radiation dose in the incidence of trigeminal dysfunction after trigeminal neuralgia radiosurgeryNicolas Massager
Gamma Knife Center, Universite Libre de Bruxelles, Brussels, Belgium
Neurosurgery 60:681-7; discussion 687-8. 2007....
Irradiation of cochlear structures during vestibular schwannoma radiosurgery and associated hearing outcomeNicolas Massager
Gamma Knife Center, University Hospital Erasme, Brussels, Belgium
J Neurosurg 107:733-9. 2007....
Role of intracanalicular volumetric and dosimetric parameters on hearing preservation after vestibular schwannoma radiosurgeryNicolas Massager
Gamma Knife Center, Erasme Hospital, Université Libre de Brixelles, Brussels, Belgium
Int J Radiat Oncol Biol Phys 64:1331-40. 2006..To analyze the relationship between hearing preservation after gamma knife radiosurgery (GKR) for vestibular schwannoma (VS) and some volumetric and dosimetric parameters of the intracanalicular components of VS...
Clinical evaluation of targeting accuracy of gamma knife radiosurgery in trigeminal neuralgiaNicolas Massager
Gamma Knife Center and Department of Neurosurgery, University Hospital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
Int J Radiat Oncol Biol Phys 69:1514-20. 2007..We also studied the applied radiation dose within the area of focal contrast enhancement on the trigeminal nerve root following radiosurgery...
Effect of beam channel plugging on the outcome of gamma knife radiosurgery for trigeminal neuralgiaNicolas Massager
Gamma Knife Center, Universite Libre de Bruxelles, Brussels, Belgium
Int J Radiat Oncol Biol Phys 65:1200-5. 2006....
Radiosurgery for trigeminal neuralgiaNicolas Massager
Gamma Knife Center, Erasme Hospital and Jules Bordet Institute, Brussels, Belgium
Prog Neurol Surg 20:235-43. 2007..e. the dose and the target. We found that the irradiation dose delivered to the brainstem, the distance between the target and the brainstem, and the occurrence of facial numbness after radiosurgery are related to a better pain outcome...
Experimental analysis of radiation dose distribution in radiosurgery. II. Dose fall-off outside the target volumeNicolas Massager
Gamma Knife Center, Erasme University Hospital, Brussels, Belgium
Stereotact Funct Neurosurg 87:137-42. 2009..We study histopathological effects of dose fall-offs outside the target using an experimental model of trigeminal nerve irradiation in the rat...
Gamma knife surgery for idiopathic trigeminal neuralgia performed using a far-anterior cisternal target and a high dose of radiationNicolas Massager
Gamma Knife Center, Department of Neurosurgery, Erasme Hospital, Brussels, Belgium
J Neurosurg 100:597-605. 2004..The authors analyzed the results of GKS in which a high dose of radiation and a distal target was used, to determine the best parameters for this treatment...
Dosimetric and clinical analysis of spatial distribution of the radiation dose in gamma knife radiosurgery for vestibular schwannomaNicolas Massager
Gamma Knife Center, Hospital Erasme, Brussels, Belgium
Int J Radiat Oncol Biol Phys 81:e511-8. 2011..We analyzed the relationship between some parameters of dose distribution and the clinical and radiological outcome of patients...
Information on heavy equipments and facilities in Belgium: gamma-knifeP David
Clinique de Neuroradiologie, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
JBR-BTR 90:252-7. 2007..To explain the principles and indications of gamma knife radiosurgery and to illustrate the correlated neuroimaging features...
Integration of the metabolic data of positron emission tomography in the dosimetry planning of radiosurgery with the gamma knife: early experience with brain tumors. Technical noteM Levivier
Gamma Knife Center of the Université Libre de Bruxelles, Brussels, Belgium
J Neurosurg 93:233-8. 2000....
The Zeiss-MKM system for frameless image-guided approach in epidural motor cortex stimulation for central neuropathic painB Pirotte
Department of Neurosurgery, Erasme Hospital, University of Brussels, Belgium
Neurosurg Focus 11:E3. 2001....
Hearing outcome after gamma knife radiosurgery for vestibular schwannoma: a prospective Belgian clinical studyC Delbrouck
ENT Department, Erasmus University Hospital, Brussels, Belgium
B-ENT 7:77-84. 2011..The purpose of this study is to report our experience with LGK radiosurgery in the management of VS and to evaluate the hearing preservation rate after a minimum one-year follow-up...
11C-methionine PET for the diagnosis and management of recurrent pituitary adenomasB N T Tang
PET Biomedical Cyclotron Unit and Department of Nuclear Medicine, Universite Libre de Bruxelles, Erasme Hospital, Brussels, Belgium
Eur J Nucl Med Mol Imaging 33:169-78. 2006..We aimed to evaluate the contribution of PET with 11C-methionine (MET-PET) in the detection and management of recurrent pituitary adenoma...
Stereotactic comparison among cerebral blood volume, methionine uptake, and histopathology in brain gliomaN Sadeghi
Department of Radiology, Hopital Erasme, Brussels, Belgium
AJNR Am J Neuroradiol 28:455-61. 2007..We used image coregistration and stereotactic biopsies to regionally compare cerebral blood volume (CBV) and (11)C-methionine (MET) uptake measurements in brain gliomas and to assess their relationship by histopathologic examination...
Preservation of hearing in vestibular schwannomas treated by radiosurgery using Leksell Gamma Knife: preliminary report of a prospective Belgian clinical studyC Delbrouck
ENT Department, Hopital Academique Erasme, Brussels, Belgium
Acta Otorhinolaryngol Belg 57:197-204. 2003..The aim of this study is to report our experience with Leksell Gamma Knife (LGK) radiosurgery in the management of VS and to evaluate the serviceable hearing preservation rate after one-year follow-up...
[In vivo evaluation of tumor response to radiosurgery: application to vestibular schwannomas]M Levivier
Centre Gamma Knife, Hopital Erasme, Universite Libre de Bruxelles, Bruxelles, Belgique
Neurochirurgie 50:320-6. 2004....
[The neurosurgery department]J Brotchi
Rev Med Brux 23:123-6. 2002....
Tumors involving the base of the skull: diagnostic and therapeutic approachesOlivier De Witte
Department of Neurosurgery, Gamma Knife Unit, Hopital Erasme, ULB, Brussels, Belgium
Curr Opin Oncol 21:238-41. 2009..SUMMARY: The knowledge of the new technology and also the result of stereotactic radiosurgery must help the physician in the choice of the treatment of skull base lesions...
Combination of functional magnetic resonance imaging-guided neuronavigation and intraoperative cortical brain mapping improves targeting of motor cortex stimulation in neuropathic painBenoit Pirotte
Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
Neurosurgery 56:344-59; discussion 344-59. 2005....
Results of positron emission tomography guidance and reassessment of the utility of and indications for stereotactic biopsy in children with infiltrative brainstem tumorsBenoit J M Pirotte
Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
J Neurosurg 107:392-9. 2007..Their aim was to assess the benefit of the technique in terms of target selection and diagnostic yield...
Internal carotid occlusion following gamma knife radiosurgery for cavernous sinus meningiomaLaurence Abeloos
Departement of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
Stereotact Funct Neurosurg 85:303-6. 2007..Therefore, we recommend shifting the hot spot during the dosimetry planning in order to reduce the incidence of such vascular injury...
Clinical impact of integrating positron emission tomography during surgery in 85 children with brain tumorsBenoit J M Pirotte
Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
J Neurosurg Pediatr 5:486-99. 2010..In this paper, the authors' goal was to evaluate the impact of PET information on brain tumor surgery in children...
Positron emission tomography-guided volumetric resection of supratentorial high-grade gliomas: a survival analysis in 66 consecutive patientsBenoit J M Pirotte
Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
Neurosurgery 64:471-81; discussion 481. 2009..The present study aims to evaluate whether PET-guided volumetric resection (VR) in supratentorial HGG might add benefit to the patient's outcome...
Clinical interest of integrating positron emission tomography imaging in the workup of 55 children with incidentally diagnosed brain lesionsBenoit J M Pirotte
Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
J Neurosurg Pediatr 5:479-85. 2010..In this paper, the authors' goal was to evaluate the impact of PET data on the clinical management of incidental brain lesions in children...
Ectopic choroid plexus associated with trigeminal neuralgia: case reportLaurence Abeloos
Departement of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 1070 Brussels, Belgium
Acta Neurochir (Wien) 152:717-9. 2010..A 55-year-old man underwent a microvascular decompression procedure for a pharmacoresistant trigeminal neuralgia. Preoperative MRI showed a neurovascular conflict between the Vth nerve root and the superior cerebellar artery...
Brain stem metastases treated with radiosurgery: prognostic factors of survival and life expectancy estimationJosé G Lorenzoni
Department of Neurosurgery, Hopital Erasme, Gamma Knife Center, Universite Libre de Bruxelles, 1000 Brussels, Belgium
Surg Neurol 71:188-95; discussion 195, 195-6. 2009..The objective of this study is to study prognostic factors of survival and 3 stratification systems for life expectancy estimation in patients with brain stem metastases treated with radiosurgery...
The integration of metabolic imaging in stereotactic procedures including radiosurgery: a reviewMarc Levivier
Centre Gamma Knife, Université Libre de Bruxelle, Départmente de Neurochirurgie, PET Cyclotron Biomedical, Hopital Erasme, Bruxelle, Belgique
J Neurosurg 97:542-50. 2002..The authors review their experience with the clinical development and routine use of positron emission tomography (PET) during stereotactic procedures, including the use of PET-guided gamma knife radiosurgery (GKS)...
Lateral positioning technique for the treatment of far-lateral targets with the Leksell gamma knife: technical noteNicolas Massager
Department of Neurosurgery and Gamma Knife Unit, Erasme Hospital, Brussels, Belgium
Neurosurgery 51:1512-7; discussion 1518-9. 2002..To describe a procedure for Leksell gamma knife (LGK) radiosurgery in a lateral position, for treatment of far-lateral intracranial lesions...
Comparison of 18F-FDG and 11C-methionine for PET-guided stereotactic brain biopsy of gliomasBenoit Pirotte
Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
J Nucl Med 45:1293-8. 2004..We compared the contributions of the labeled tracers (11)C-methionine (Met) and (18)F-FDG for PET-guided stereotactic biopsy of brain gliomas...
Use of the Leksell gamma knife C with automatic positioning system for the treatment of meningioma and vestibular schwannomaMarc Levivier
Centre Gamma Knife of the Universite Libre de Bruxelles, Brussels, Belgium
Neurosurg Focus 14:e8. 2003..The authors report their experience using the Leksell gamma knife C (GK-C) for the treatment of meningioma and vestibular schwannoma (VS)...
Synovial cysts of the lumbar spine: surgery-related results and outcomeBenoit Pirotte
Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
J Neurosurg 99:14-9. 2003..The authors conducted a study to determine the surgery-related results and outcomes in patients with synovial cysts of the lumbar spine. They emphasize several specific characteristics useful in clinical management...
Combined use of 18F-fluorodeoxyglucose and 11C-methionine in 45 positron emission tomography-guided stereotactic brain biopsiesBenoit Pirotte
Department of Neurosurgery, PET Biomedical Cyclotron Unit, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
J Neurosurg 101:476-83. 2004..The aim of this study was to compare the contribution of the tracers 11C-methionine (Met) and 18F-fluorodeoxy-glucose (FDG) in positron emission tomography (PET)-guided stereotactic brain biopsy...
Voxel-based assessment of spinal tap test-induced regional cerebral blood flow changes in normal pressure hydrocephalusNicolas E Dumarey
Department of Nuclear Medicine and PET Biomedical Cyclotron Unit, Hopital Erasme, Universite Libre de Bruxelles, 808 Route de Lennik, B 1070 Brussels, Belgium
Nucl Med Commun 26:757-63. 2005..The objective of this study was to evaluate, by SPM, spinal tap test-induced rCBF changes in patients with NPH syndrome...
Comparison of functional MR imaging guidance to electrical cortical mapping for targeting selective motor cortex areas in neuropathic pain: a study based on intraoperative stereotactic navigationBenoit Pirotte
Department of Neurosurgery, Erasme Hospital, University of Brussels, Brussels, Belgium
AJNR Am J Neuroradiol 26:2256-66. 2005..These data illustrate the functional accuracy of fMRI guidance for the operative targeting of selective motor cortex areas in neuropathic pain...
Integrated positron emission tomography and magnetic resonance imaging-guided resection of brain tumors: a report of 103 consecutive proceduresBenoit Pirotte
Department of Neurosurgery, PET Cyclotron Biomédical Unit, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
J Neurosurg 104:238-53. 2006..The aim of this study was to evaluate the integration of positron emission tomography (PET) scanning data into the image-guided resection of brain tumors...
Use of stereotactic PET images in dosimetry planning of radiosurgery for brain tumors: clinical experience and proposed classificationMarc Levivier
Department of Neurosurgery and Centre Gamma Knife, Hôpital Erasme and Université Libre de Bruxelles, Brussels, Belgium
J Nucl Med 45:1146-54. 2004..e., PET) and anatomic (i.e., MRI and CT) images for the radiosurgical treatment of brain tumors. We propose a classification describing the relative role of the information provided by PET in this multimodality image-guided approach...
Integration of functional imaging in radiosurgery: the example of PET scanMarc Levivier
Gamma Knife Center, Universite Libre de Bruxelles, Brussels, Belgium
Prog Neurol Surg 20:68-81. 2007..The use of a standardized classification allows to assess the relative role of PET. A similar approach could be useful and may serve as a template for the evaluation of the integration of other new imaging modalities in radiosurgery...
[Non-functioning pituitary adenoma: is there an interest to treat a residue after surgery?]O De Witte
Service de Neurochirurgie, Hopital Erasme, Bruxelles
Rev Med Brux 32:509-12. 2011..A complete surgery must be the aim of the neurosurgeon. And when a residue is present, a secondary treatment must be given for patient with an age below 60 years old like radiosurgery or radiation therapy...
Trigeminal neuralgia. Pathophysiology and treatmentA Joffroy
Dept. of Neurosurgery, Erasmus Hospital, University of Brussels (ULB, Brussels, Belgium
Acta Neurol Belg 101:20-5. 2001..Therapeutic options are reviewed: very efficient drugs are available but fail to provide a significant relief and/or have important side effects in many cases. Surgical alternatives are available, for which guidelines are proposed...
Modern multimodal neuroimaging for radiosurgery: the example of PET scan integrationM Levivier
Neurosurgery and Gamma Knife Center, ULB Hopital Erasme, Brussels, Belgium
Acta Neurochir Suppl 91:1-7. 2004..The use of a standardized classification allows to assess the relative role of PET. A similar approach could be useful and may serve as a template for the evaluation of the integration of other new imaging modalities in radiosurgery...
Three-dimensional Gaussian model to define brain metastasis limits on 11C-methionine PETBich Ngoc Thanh Tang
Department of Nuclear Medicine and PET Biomedical Cyclotron Unit, Brussels, Belgium
Radiother Oncol 89:270-7. 2008..We choose MET-PET and MRI data obtained in brain metastases to adjust the model. Indeed, MRI limits of these non-infiltrative hypermetabolic brain lesions are efficiently used for their curative treatment...
Neurovascular compression anatomy and pain outcome in patients with classic trigeminal neuralgia treated by radiosurgeryJosé G Lorenzoni
Department of Neurosurgery, School of Medicine, Pontifica Universidad Catolica de Chile, Santiago, Chile
Neurosurgery 62:368-75; discussion 375-6. 2008..To study the influence of the anatomy of neurovascular compression (NVC) on pain outcome in patients with classic trigeminal neuralgia treated by radiosurgery...
Pathological findings following trigeminal neuralgia radiosurgeryGyorgy T Szeifert
National Institute of Neurosurgery and Department of Neurological Surgery, Semmelweis University, Budapest, Hungary
Prog Neurol Surg 20:244-8. 2007..Autopsy revealed a neurovascular conflict close to the second radiosurgery shot. Histopathology demonstrated acute and chronic stage radiation-induced lesions in the trigeminal nerve...
