H Malonne

Summary

Country: Belgium

Publications

  1. ncbi Preparation of poly(N-isopropylacrylamide) copolymers and preliminary assessment of their acute and subacute toxicity in mice
    Hugues Malonne
    Laboratoire de Physiologie et de Pharmacologie Fondamentales, Institut de Pharmacie, Universite Libre de Bruxelles, Belgium
    Eur J Pharm Biopharm 61:188-94. 2005
  2. ncbi Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain
    H Malonne
    Laboratoire de Physiologie et de Pharmacologie, Institut de Pharmacie, Unversité Libre de Bruxelles, Brussels, Belgium
    J Clin Pharm Ther 30:113-20. 2005
  3. ncbi Impact of montelukast on symptoms in mild-to-moderate persistent asthma and exercise-induced asthma: results of the ASTHMA survey. Adding Singulair Treatment to Handle symptoms in Mild to moderate Asthmatics
    Hugues Malonne
    Department of Physiology and Pharmacology, Free University of Brussels, Boulevard du Triomphe, 1050 Brussels, Belgium
    Curr Med Res Opin 18:512-9. 2002
  4. ncbi Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol
    H Malonne
    Laboratoire de Physiologie et de Pharmacologie, Campus Plaine CP 206 3, Institut de Pharmacie, Universite Libre de Bruxelles, 1050 Bruxelles, Belgium
    Br J Clin Pharmacol 57:270-8. 2004
  5. ncbi Efficacy and tolerability of sustained-release tramadol in the treatment of symptomatic osteoarthritis of the hip or knee: a multicenter, randomized, double-blind, placebo-controlled study
    Hugues Malonne
    Laboratoire de Physiologie et de Phannacologie, CP206 3, Institut de Pharmacie, Universite Libre de Bruxelles, 1050 Bruxelles, Belgium
    Clin Ther 26:1774-82. 2004
  6. ncbi Mechanisms of tumor angiogenesis and therapeutic implications: angiogenesis inhibitors
    H Malonne
    Laboratoire de Pharmacologie, Institut de Pharmacie, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Exp Metastasis 17:1-14. 1999
  7. ncbi Cytotoxic constituents from Plumbago zeylanica
    A T Nguyen
    Laboratoire de Physiologie et de Pharmacologie Fondamentales, Institut de Pharmacie CP 205 7, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Fitoterapia 75:500-4. 2004
  8. ncbi A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    J Gusman
    Laboratoire de Pharmacognosie et Bromatologie CP205 4, Institut de Pharmacie, Universite Libre de Bruxelles, Campus Plaine, Boulevard du Triomphe, 1050 Brussels, Belgium
    Carcinogenesis 22:1111-7. 2001
  9. ncbi A sugar ester and an iridoid glycoside from Scrophularia ningpoensis
    Anh Tho Nguyen
    Laboratory of Pharmacognosy, Bromatology and Human Nutrition, Institute of Pharmacy CP 205 9, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Phytochemistry 66:1186-91. 2005
  10. ncbi Homoisoflavanones from Disporopsis aspera
    Anh Tho Nguyen
    Laboratory of Pharmacognosy, Bromatology and Human Nutrition, Institute of Pharmacy CP 205 9, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Phytochemistry 67:2159-63. 2006

Detail Information

Publications11

  1. ncbi Preparation of poly(N-isopropylacrylamide) copolymers and preliminary assessment of their acute and subacute toxicity in mice
    Hugues Malonne
    Laboratoire de Physiologie et de Pharmacologie Fondamentales, Institut de Pharmacie, Universite Libre de Bruxelles, Belgium
    Eur J Pharm Biopharm 61:188-94. 2005
    ..In addition, the subacute study indicated the absence of cumulative toxicity and a no-observed-adverse-effect level (NOAEL) of 2000 mg/kg was identified for PNIPAAm and its two copolymers. Further studies are mandatory...
  2. ncbi Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain
    H Malonne
    Laboratoire de Physiologie et de Pharmacologie, Institut de Pharmacie, Unversité Libre de Bruxelles, Brussels, Belgium
    J Clin Pharm Ther 30:113-20. 2005
    ..The purpose of the study was to assess the long-term safety of a new sustained-release formulation of tramadol (tramadol LP) in patients with knee or hip osteoarthritis and in patients with refractory low back pain...
  3. ncbi Impact of montelukast on symptoms in mild-to-moderate persistent asthma and exercise-induced asthma: results of the ASTHMA survey. Adding Singulair Treatment to Handle symptoms in Mild to moderate Asthmatics
    Hugues Malonne
    Department of Physiology and Pharmacology, Free University of Brussels, Boulevard du Triomphe, 1050 Brussels, Belgium
    Curr Med Res Opin 18:512-9. 2002
    ....
  4. ncbi Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol
    H Malonne
    Laboratoire de Physiologie et de Pharmacologie, Campus Plaine CP 206 3, Institut de Pharmacie, Universite Libre de Bruxelles, 1050 Bruxelles, Belgium
    Br J Clin Pharmacol 57:270-8. 2004
    ....
  5. ncbi Efficacy and tolerability of sustained-release tramadol in the treatment of symptomatic osteoarthritis of the hip or knee: a multicenter, randomized, double-blind, placebo-controlled study
    Hugues Malonne
    Laboratoire de Physiologie et de Phannacologie, CP206 3, Institut de Pharmacie, Universite Libre de Bruxelles, 1050 Bruxelles, Belgium
    Clin Ther 26:1774-82. 2004
    ....
  6. ncbi Mechanisms of tumor angiogenesis and therapeutic implications: angiogenesis inhibitors
    H Malonne
    Laboratoire de Pharmacologie, Institut de Pharmacie, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Exp Metastasis 17:1-14. 1999
    ..This knowledge has permitted the design of receptor antagonists, adhesion molecule blockers and new targeted vascular approaches including gene therapy...
  7. ncbi Cytotoxic constituents from Plumbago zeylanica
    A T Nguyen
    Laboratoire de Physiologie et de Pharmacologie Fondamentales, Institut de Pharmacie CP 205 7, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Fitoterapia 75:500-4. 2004
    ..5 microM) and plumbagin was cytotoxic against MCF7 and Bowes cells (IC50 1.28 microM and 1.39 microM, respectively)...
  8. ncbi A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    J Gusman
    Laboratoire de Pharmacognosie et Bromatologie CP205 4, Institut de Pharmacie, Universite Libre de Bruxelles, Campus Plaine, Boulevard du Triomphe, 1050 Brussels, Belgium
    Carcinogenesis 22:1111-7. 2001
    ..These include cyclooxygenase, nitric oxide synthase and cytochrome P450 inhibition, as well as cell cycle effects, apoptosis modulation and hormonal activity...
  9. ncbi A sugar ester and an iridoid glycoside from Scrophularia ningpoensis
    Anh Tho Nguyen
    Laboratory of Pharmacognosy, Bromatology and Human Nutrition, Institute of Pharmacy CP 205 9, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Phytochemistry 66:1186-91. 2005
    ..9, 43.6 microM on T24S; 61.3, 151.5 microM on A549, respectively. Beta-sitosterol (8) inhibited Bowes cells growth at IC50=36.5 microM. Scrophuloside B4 (2) showed activity on K562 and Bowes cells at IC50=44.6, 90.2 microM, respectively...
  10. ncbi Homoisoflavanones from Disporopsis aspera
    Anh Tho Nguyen
    Laboratory of Pharmacognosy, Bromatology and Human Nutrition, Institute of Pharmacy CP 205 9, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Phytochemistry 67:2159-63. 2006
    ..Possible biosynthesis routes for homoisoflavonoids (1-4) are discussed...
  11. ncbi In vitro/in vivo characterization of a tramadol HCl depot system composed of monoolein and water
    H Malonne
    Laboratoire de Pharmacie Galénique et de Biopharmacie, Institut de Pharmacie, Universite Libre de Bruxelles, Belgium
    Biol Pharm Bull 23:627-31. 2000
    ..The sustained-release capabilities were evaluated by using a modified half value duration (HVD) ratio and all sustained-released formulations exhibited a HVD ratio equal or superior to 3.9...