Research Topics
| Raphael LeplaeSummaryCountry: Belgium Publications
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Detail Information
Publications
ACLAME: a CLAssification of Mobile genetic ElementsRaphael Leplae
Service de Conformation de Macromolécules Biologiques et de Bioinformatique, Universite Libre de Bruxelles, Belgium
Nucleic Acids Res 32:D45-9. 2004....
A first global analysis of plasmid encoded proteins in the ACLAME databaseRaphael Leplae
SCMBB, Universite Libre de Bruxelles, Bvd du Triomphe, Bruxelles, Belgium
FEMS Microbiol Rev 30:980-94. 2006....
ACLAME: a CLAssification of Mobile genetic Elements, update 2010Raphael Leplae
Bioinformatique des Génomes et des Réseaux, Universite Libre de Bruxelles, Boulevard du Triomphe, 1050 Bruxelles, Belgium
Nucleic Acids Res 38:D57-61. 2010..ulb.ac.be). The BLAST interface for querying the database has been extended and numerous tools for in-depth analysis of the results have been added...
Prophinder: a computational tool for prophage prediction in prokaryotic genomesGipsi Lima-Mendez
Laboratoire de Bioinformatique des Génomes et des Réseaux BiGRe, Universite Libre de Bruxelles, 1050 Bruxelles, Belgium
Bioinformatics 24:863-5. 2008..AVAILABILITY: Softare is available at http://aclame.ulb.ac.be/prophinder..
PhiGO, a phage ontology associated with the ACLAME databaseAriane Toussaint
Service de Conformation de Macromolécules Biologiques et de Bioinformatique, Universite Libre de Bruxelles, ULB, Bvd du Triomphe, Campus Plaine CP 263, B1050 Bruxelles, Belgium
Res Microbiol 158:567-71. 2007..PhiGO uses the Gene Ontology schema, the de facto standard for describing knowledge about gene products across many databases...
Analysis of the phage sequence space: the benefit of structured informationGipsi Lima-Mendez
Service de Conformation de Macromolécules Biologiques et de Bioinformatique, Universite Libre de Bruxelles, CP 263, Boulevard du Triomphe, 1050, Bruxelles, Belgium
Virology 365:241-9. 2007....
Reticulate representation of evolutionary and functional relationships between phage genomesGipsi Lima-Mendez
Service de Bioinformatique des Génomes et des Réseaux BiGRe, Universite Libre de Bruxelles, Bruxelles, Belgium
Mol Biol Evol 25:762-77. 2008..These 2 classification schemes provide an automatic and dynamic way of representing the relationships within the phage population and can be extended to include newly sequenced phage genomes, as well as other types of genetic elements...
Evidence for copper homeostasis function of metallothionein (MT3) in the hyperaccumulator Thlaspi caerulescensNancy H Roosens
Laboratoire de Physiologie et Génétique Moléculaire des Plantes, Universite Libre de Bruxelles, Campus Plaine CP 242 Bld du triomphe, B 1050 Brussels, Belgium
FEBS Lett 577:9-16. 2004..thaliana than for T. caerulescens. Functional testing in yeast and Northern blot analysis added further evidence for adaptative variations of MT3 for the maintenance of Cu homeostasis in a metal hyperaccumulator...
Variations in plant metallothioneins: the heavy metal hyperaccumulator Thlaspi caerulescens as a study caseNancy H Roosens
Laboratoire de Physiologie et Génétique Moléculaire des Plantes, Universite Libre de Bruxelles, Campus Plaine CP 242 Bd du triomphe, 1050, Brussels, Belgium
Planta 222:716-29. 2005..caerulescens than in A. thaliana. Moreover, their differential expression patterns in organs and in response to metal exposure, suggest that the two types of MTs may have diverse roles and functions in T. caerulescens...
The biphenyl- and 4-chlorobiphenyl-catabolic transposon Tn4371, a member of a new family of genomic islands related to IncP and Ti plasmidsAriane Toussaint
SCMBB, Universite Libre de Bruxelles, Brussels, Belgium
Appl Environ Microbiol 69:4837-45. 2003..Tn4371 thus appears to represent a new family of potentially mobile genomic islands with a broad host range since they reside in a wide range of soil proteobacteria, including plant pathogens...
Diversity of bacterial type II toxin-antitoxin systems: a comprehensive search and functional analysis of novel familiesRaphael Leplae
Laboratoire de Bioinformatique des Génomes et des Réseaux BiGRe, Faculte des Sciences, Universite Libre de Bruxelles, Bld du Triomphe, 1050 Bruxelles, Belgium
Nucleic Acids Res 39:5513-25. 2011..Therefore, addiction might play a major role in the evolutionary success of TA systems both on mobile genetic elements and in bacterial chromosomes...
Genetic diversity of Group A Streptococcus M protein: implications for typing and vaccine developmentPierre R Smeesters
Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium
Vaccine 26:5835-42. 2008....
